Become a Paid Subscriber: https://anchor.fm/dr-daniel-j-guerra/subscribe Become a Paid Subscriber: https://anchor.fm/dr-daniel-j-guerra/subscribe You have wisely landed upon Authentic Biochemistry, with Dr. Daniel J Guerra, where published biochemical, physiological, genetic and immunological research along with biomedical and pharmaceutical science are interrogated. Support this podcast: https://podcasters.spotify.com/pod/show/dr-daniel-j-guerra/support
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Immune Cell Biochemistry II.B lymphocyte VDJ recombination is controlled by multiple methyltransferase mechanisms. Dr Daniel J. Guerra. 01June2024.Authentic Biochemistry.
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References Guerra, DJ. 2024. ImmunoBiochemistry lectures. Commun Biol. 2022; 5: 1292. ACS Chem. Biol. 2017, 12, 4, 958–968Telemann, GP., 1750. Sonata in D major, TWV 44:1https://youtu.be/xx8ooc-s7OQ?si=1vAKmdcLroNISa-P Vivaldi, A., 1708. - Gloria (RV 589) https://youtu.be/2eWjQOdYzMQ?si=hYSOqRuXkYUA8ATl --- Send in a voice message: https://podcaste…
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Immune Cell Biochemistry. Bcell Electron transport control via calcium mobilization after BCR activation. DJGPhD. 14.6.24. Authentic biochemistry Podcast
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References Guerra, Daniel J. 2024. Electron transport chain lectures Nature Immunology 2018. volume 19: 871–884 Leach, D. (Allman Brothers Band) 1971. Live at Fillmore East https://youtu.be/w9ZubobGMLs?si=30X6auZQPzrhcB4O --- Send in a voice message: https://podcasters.spotify.com/pod/show/dr-daniel-j-guerra/messageSupport this podcast: https://pod…
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Immune Cell Biochemistry.c.10 Primer on Mitochondrial Bioenergetics I. DJGPhD.13.6.24
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References Guerra, Daniel J. 2024. Bioenergetics lectures Hunter, R. 1975. "Cruel White Water" https://youtu.be/T-oBD3F74Nk?si=_b3ksQfgbaUEqHA8 Beethoven, LV. 1808. Symphony No. 6 in F, Op. 68 https://youtu.be/xWDIwsfgQnE?si=-vFCnYfdtpivpLnt --- Send in a voice message: https://podcasters.spotify.com/pod/show/dr-daniel-j-guerra/messageSupport this …
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Immune Cell biochemistry. BCR activation results in mitochondrial alteration in ETC and OXPHOS. DJGPhD. 12June24 Authentic Biochemistry.
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References Biophys Res Commun. 2024 Mar 12:700:149598. Eur J Pharmacol.2002 May 17;443(1-3):189-96Nature Immunology2018 volume 19, 871–884 Mozart, WA 1785. C Major String Quartet 19. K 465 (The Dissonance" https://youtu.be/f3oK4XVMARs?si=xjTTKrC0OL-V1xkX --- Send in a voice message: https://podcasters.spotify.com/pod/show/dr-daniel-j-guerra/message…
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Immune Cell Biochemistry II. B cells. Two-component B cell activation requires Tfh and/or TLR9 signaling to mediate glucose metabolism for bioenergetic demands. DJGPhD. 10June24
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References Nature Immunology 2018. volume 19, pages:871–884 Jon Anderson, Chris Squire, and Bill Bruford 1971. "Heart of the Sunrise". Yes. https://youtu.be/0vNcgL9Fi4w?si=DkXqwHwIEuQcTiMt --- Send in a voice message: https://podcasters.spotify.com/pod/show/dr-daniel-j-guerra/messageSupport this podcast: https://podcasters.spotify.com/pod/show/dr-d…
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Immune Cell Biochemistry B lymphocyte c.7
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References MAbs. 2022; 14(1): 2107971Commun Biol. 2022; 5: 1292 --- Send in a voice message: https://podcasters.spotify.com/pod/show/dr-daniel-j-guerra/messageSupport this podcast: https://podcasters.spotify.com/pod/show/dr-daniel-j-guerra/support
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Immune Cell Biochemistry II. B cells The Methyltransferase regulation of RAG 2. Dr Daniel J. Guerra. 29May24. Authentic Biochemistry Podcast
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References Guerra, DJ. ImmunoBiochemistry lectures 2024. ACS Chem. Biol. 2017, 12, 4, 958–968 Genome Biol. 2005; 6(8): 227 Manfredini, FO. 1718. 12 Concerti Grossi | Op. 3 https://youtu.be/4t-E3wlMkDQ?si=GX0GCLUm48J4V8OY --- Send in a voice message: https://podcasters.spotify.com/pod/show/dr-daniel-j-guerra/messageSupport this podcast: https://podc…
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Immune Cell Biochemistry II. B Cell Event Ontology. 28May24. Authentic Biochemistry Podcast. Dr Daniel J. Guerra
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References ACS Chem. Biol. 2017, 12, 4, 958–968 Nat Rev Immunol. 2016 Apr; 16(4): 234–246 Guerra, DJ. 2024. Immuno-Biochemistry Lectures Vivaldi, A. 1705. Trio Sonata in D minor, RV 63 https://youtu.be/kPpaeW3DObU?si=nfJmUWlmiK8BZXxD Albinoni , T. 1708. Adagio in G Minor https://youtu.be/z6WOfH2kV00?si=Mf7_6JwuLETu7YEC Scarlotti, D. 1720. Fandango …
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Immune Cell Biochemistry II. Authentic Biochemistry Podcast. B cell Biochemistry c4. Dr Daniel J. Guerra 27.5.24.
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References Guerra, DJ. 2024. Immunology Lectures (archives). Pisendel, JG. 1720. : Concerto in E-flat major or Violin, Strings & B.c Jun P I.3 https://youtu.be/SZI2IgOOSPU?si=8xNIyvzxPnkV2zlK Biber, HI. 1676. Passacaglia. G- minor, C.105 https://youtu.be/sgcR183f8gA?si=vYnlxQJDq8LgG_B4 --- Send in a voice message: https://podcasters.spotify.com/pod…
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Authentic Biochemistry Podcast. B-Cell Membrane Biochemistry.c.3. Dr. Daniel J. Guerra. 26.5.24
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References Cancer Science June 2014. 105(9) Acc Chem Res. 2021 May 4;54(9):2110-2120. Nat Immunol. 2022 Jan; 23(1): 99–108. . Bach, JS. 1704.Toccata and Fugue in D minor BWV 565 https://youtu.be/erXG9vnN-GI?si=o6YlpjXM2dRLpyZQ Leach, D. 1965"Catch the Wind" https://youtu.be/J8hjEYTpwE8?si=XeWU1HSy6CGBlEeT --- Send in a voice message: https://podcas…
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Authentic Biochemistry Podcast. B Cell Membrane Biochemistry.c.2.Dr. Daniel J. Guerra. 25.5.24
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References Cellular & Molecular Immunology. 2018. volume 15, pages676–684. Stem Cells Int. 2020: 1047896. Published online Jul 8 Cancer Science. 2014. June.105(9) --- Send in a voice message: https://podcasters.spotify.com/pod/show/dr-daniel-j-guerra/messageSupport this podcast: https://podcasters.spotify.com/pod/show/dr-daniel-j-guerra/support…
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Immune Cell Biochemistry II. B Cell Membranes. Introductory Lecture. Dr Daniel J. Guerra. 22May24 Authentic Biochemistry.
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References Nat Commun. 2022; 13: 5371 Schubert, F. 1822.Symphony No. 8 in B Minor "Unfinished," D. 759 https://youtu.be/3tisvEpblig?si=WLsVj4R6gedi7-_a --- Send in a voice message: https://podcasters.spotify.com/pod/show/dr-daniel-j-guerra/messageSupport this podcast: https://podcasters.spotify.com/pod/show/dr-daniel-j-guerra/support…
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Authentic Biochemistry Podcast Philosophical Interlude. The Epistemological concurrence of biochemical research with dialectical event ontology. Dr Dan Guerra 20.5.24.
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References Guerra, DJ. 2019-2024. Previous public lectures and podcasts. Bach, JS. 1721 Brandenburg Concerto No. 2 in F major, BWV 1047 https://youtu.be/3HSRIDtwsfM?si=AA-KdJF2Hyq8RlrE --- Send in a voice message: https://podcasters.spotify.com/pod/show/dr-daniel-j-guerra/messageSupport this podcast: https://podcasters.spotify.com/pod/show/dr-danie…
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T cell Membrane Biochemistry. FINE c.25. 18 May 2024.Authentic Biochemistry Podcast.Dr Daniel J. Guerra
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References Nature 2024.volume 629, pages 417–425Front. Immunol., 26 April 2019 Sec. NK and Innate Lymphoid Cell Biology. Nature Communications 2020.volume 11. Article 2437 Scientific Reports 2018. volume 8.Article 8700 Int J Mol Sci. 2020 Sep; 21(18): 6497 Hunter-Garcia& Lesh,P. 1969. "Cumberland Blues" On [Workingman's Dead lp.] https://youtu.be/x…
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T Cell Membrane Biochemistry Fine C24. Endometrial Cancer NK cells:a biochemical pseudoparadox revealing event ontology dialectics. Dr Daniel J. Guerra. 17.5.24
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References Nature Communications 2020. volume 11, Article:2437 Scientific Reports. 2018. volume 8, Article 8700 Front. Immunol., 26 April 2019 Sec. NK and Innate Lymphoid Cell Biology --- Send in a voice message: https://podcasters.spotify.com/pod/show/dr-daniel-j-guerra/messageSupport this podcast: https://podcasters.spotify.com/pod/show/dr-daniel…
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Authentic Biochemistry Podcast. T cell Membrane Lipid Biochemistry c.23 Fine I. 15.5.24. Dr. Daniel J. Guerra
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References Biol Sex Diff. 2021.12:64 Nature 2024. volume 629, pages 417–425 Int. J. Mol. Sci. 2019, 20(3), 646 Front. Immunol.2109. 09 October Sec. Cancer Immunity and Immunotherapy. Volume 10Schubert, F. 1814-15. Symphonie 2. in B♭ major, D. 125https://youtu.be/-26Gt4rGaQA?si=_C7MXMG-0piT_4eV Donovan.1968 "Lalena" https://youtu.be/1kA3nZwGHHA?si=f…
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Immune Cell Biochemistry. T cell Membranes Coda VII. C.22 Dr Daniel J. Guerra. Authentic Biochemistry 13.5.24
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Cancers (Basel). 2023 Nov; 15(21): 5177 GUERRA, DANIEL J.(2022)CYTOEPIGENETICS: DIALECTICAL REVIEW OF A SUBCELLULAR ENDO-MEMBRANOUS COORDINATION OF GENE EXPRESSION AND CELLULAR FATE. Journal of Disease and Global Health, 15 (3). pp. 22-47. ISSN 2454-1842 McCartney-Lennon. 1968 "Martha My Dear." https://youtu.be/RXawa90YU2s?si=_CgaG0yOdbpcflYr --- S…
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Immune Cell Biochemistry. T cell Membranes. Coda VI. c.21 Methylation Specific Treg differentiation I. 11May24. DJGPhD Authentic Biochemistry Podcast
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References Acta Pharmacol Sin. 2019 Aug;40(8): 1076–1084 Nucleus. 2022; 13(1): 236–276. Cancers (Basel). 2023 Nov; 15(21): 5177 Dylan, R. 1965 "Like a Rolling Stone" https://youtu.be/IwOfCgkyEj0?si=1vnIW2vqfsg-9MGp Dvorak, A. 1893. Symphony 9 in E minor. Op.95.B178. "From the New World" https://youtu.be/jOofzffyDSA?si=LiM8g7l487jmD22J --- Send in a…
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Immune Cell Biochemistry.Tcell Membranes. Coda V. C.20
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References Cancers (Basel). 2023 Nov; 15(21): 5177Front Oncol. 2021; 11: 750789 --- Send in a voice message: https://podcasters.spotify.com/pod/show/dr-daniel-j-guerra/messageSupport this podcast: https://podcasters.spotify.com/pod/show/dr-daniel-j-guerra/support
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Immune Cell Biochemistry I. T cell Membrane Biochemistry. CODA-IV. C.19. Authentic Biochemistry Podcast. Dr. Daniel J. Guerra . 07May24
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References Cancers (Basel). 2023 Nov; 15(21): 5177. Cancer Discov. 2022 Mar 1; 12(3): 856–871 Gastroenterology. 2023 Feb;164(2): 256–271.e10. Jagger-Richards 1966. "Ruby Tuesday" [Between the Buttons, lp.) Rolling Stones. https://youtu.be/mAyj9q2quYc?si=fv07ARFvr0P2hEAs Schubert, F. 1816. Symphony No. 5 in B♭ major, D. 485. https://youtu.be/OHkot1T…
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Immune Cell Biochemistry I. T Cell Membranes CoDA3/C.18 Authentic Biochemistry Dr. Daniel J. Guerra 06MAY24
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References Gastroenterology. 2023 Feb; 164(2): 256–271.e10. Ada R. Habershon, and Charles H. Gabriel. 1907. "Will the Circle Be Unbroken" Performed by the Carter Family incl. Johnny Cash. https://youtu.be/JLFbUbmH7To?si=rLPSkV-mHYq3Aodf Mozart, WA. 1783. Mass in C Minor K. 427. https://youtu.be/KsiP4-mCnQ0?si=XoNwMiTO1JK5jPOK --- Send in a voice me…
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Immune Cell Biochemistry I. T Cell Membranes c.17 Authentic Biochemistry Dr. Daniel J. Guerra 05MAY24
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References The Journal of Biological Chemistry2018 293, 19001-19011 Cell Death & Disease volume 10, Article number: 315 Experimental & Molecular Medicine 2019. volume 51, Article number: 80. Trends in Immunology. 2017. REVIEW| VOL. 38,Issue 4, P287-297, April 01. Gastroenterology. 2023 Feb; 164(2): 256–271.e10 Squire/ Anderson. 1971. "The South Sid…
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Immune Cell Biochemistry I. T cell Membrane Biochemistry.CODA 1.Authentic biochemistry Podcast.Dr. Daniel J. Guerra
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References Gastroenterology. 2023 Feb;164(2): 256–271.e10. The Journal of Biological Chemistry 2018 293, 19001-19011 Leitch, D. 1965 "Catch the Wind" https://youtu.be/J8hjEYTpwE8?si=VfSaLDcP5JxzzP-p Hendrix, J. 1967. "The Wind Cries Mary" https://youtu.be/ARO2vbGFLJM?si=_IIEFN0BOEy6DfqW Bach, JS. 1717. Partita in D Minor, BWV 1004 https://youtu.be/…
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Immune Cell Biochemistry I. T Lymphocyte Membrane.C.15. Authentic Biochemistry Podcast.Dr Daniel J. Guerra.01May2024.
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References Trends in Immunology. 2017. REVIEW| VOLUME 38, ISSUE 4, P287-297. FASEB J. 2020 May;34(5):6185-6197. Couperin, F. 1714. Troisième Leçon De Ténèbres À 2 Voix https://youtu.be/UbREakKFTow?si=JqmA1GQQpTOItUSg Lennon-McCartney. 1970. "Let it Be" https://youtu.be/QDYfEBY9NM4?si=nH4LJs4gprJVvcR1 --- Send in a voice message: https://podcasters.…
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Immune Cell Biochemistry I. T Lymphocyte Membrane.C.14 Authentic Biochemistry Podcast. Dr Daniel J. Guerra. 30.4.24 .
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References Nutrition. 2021-11-01, Volume 91, Article 111388 Front Immunol. 2022 Jan 5:12:806529. Cells. 2019 Aug; 8(8): 939. Lennon-McCartney 1963."She Loves You" [Beatles Second Album; lp] https://youtu.be/oVCwDl-S09A?si=ZjD89e5pwvXf5864 Schmelzer, JH, 1664 " Violin Sonata, in A Minor. 'Cucù'" https://youtu.be/x1TsJFeB2x8?si=JiqwHG2GcOf2ddeT --- S…
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Immune Cell Biochemistry I. T Lymphocyte Membrane c.13. Authentic Biochemistry Podcast. Dr .Daniel J. Guerra.28.4.24 .
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References Int J Mol Sci. 2019 Oct; 20(20): 5028 Nutrition. 2021-11-01, Volume 91, Article 111388 Bach, JS. 1720. "Brandenburg Concerto No. 6" in B Flat Major. BMV. 1051. https://youtu.be/_tr_uYEQkrs?si=rXXWMBAnWGbEuAOk Hunter-Garcia. 1970. "Stella Blue". [Wake of the Flood;lp] https://youtu.be/VKsWDyvWaL4?si=DnHgzSEiiKeUOXbj --- Send in a voice me…
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Immune Cell Biochemistry I. T Lymphocyte Membrane Biochemistry c.12. Omega -3 fatty acids and mdiminished macrophage inflammatory gene expression. Dr. Daniel J. Guerra Authentic Biochemistry 26..4.24
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References Int J Mol Sci. 2019 Oct; 20(20): 5028. Lennon-McCartney. 1964. "Ill Be Back" https://youtu.be/fJSTBNTac6k?si=rr4rWE86TIs8EZcL Bruch, M. 1866. Violin Concerto 1. G minor https://youtu.be/9BeV9XDs64w?si=AvEAQch7T8TJrt05 --- Send in a voice message: https://podcasters.spotify.com/pod/show/dr-daniel-j-guerra/messageSupport this podcast: http…
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A brief introduction to an epistemological dialectic directed toward research science. Dr. Daniel J. Guerra. 25.4.2924. Authentic Biochemistry Podcast
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Kant, I. 1791 "Critique of Pure Reason" Augustinus, A. 397. "Confessiones" Book 11. Plotinus 253. "Ennead III" Beethoven,L. 1799. Septet Es-Dur op. 20 https://youtu.be/pXsj43qCcUA?si=lWoBhVSC4WhT8uUP Winwood-Capaldo. 1970. "Empty Pages " [Traffic: John Barleycorn Must Die,lp] https://youtu.be/5ycyIkcX7zU?si=jUJ6U2u31_SL1vNR --- Send in a voice mess…
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Immune Cell Biochemistry I. T Lymphocyte Membrane Biochemistry c.11. Dr. Daniel J. Guerra. Authentic Biochemistry. 24.4.24
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References Circulation. 2023.Oct 17;148(16):1231-1249. Int J Mol Sci . 2019. Oct 11;20(20):5028. Front Immunol. 2019; 10: 1706 Mastin, T. 1967 "How do you Feel" [Jefferson Airplane]. Surrealistic Pillow.lp. https://youtu.be/iWUa-rKT-oY?si=1M9496MbDUBGuj0A Hunter, Garcia, Kreutzman. 1975. "Franklin's Tower" [ Grateful Dead. Blues for Alah].lp. https…
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Immune Cell Biochemistry I. T Lymphocyte Membrane Biochemistry c.10. Immune cell membrane glycosphingolipids. Dr. Daniel J. Guerra Authentic Biochemistry 23.4.24.
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References Guerra, D. 2023-24 lipid lectures J Oleo Sci. 2011; 60(10): 537–544. Gregorian Chants: 1100 AD. Beata es Virgo Maria https://youtu.be/rMlWhAh2Zvc?si=B3XqzCsQYef_ee6t Schubert, F. 1822. Schubert | Mass No. 5 in A flat major D 678 https://youtu.be/Yl5YF3PeUeI?si=AP9U_WHULnv3ItWi --- Send in a voice message: https://podcasters.spotify.com/p…
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Immune Cell Biochemistry I. T lymphocyte Membrane Biochemistry. c.9. The involved CH2O sequence event ontology. DJGPhD.22.4.24
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References J Am Soc Mass Spectrom. 2023 Nov 1;34(11):2481-2490 J Oleo Sci. 2011; 60(10): 537–544. Trends Immunol. 2018 Jul; 39(7): 523–535. Blood. 2014 Dec 4; 124(24): 3656–3665. George, L. and B. Payne. 1970. "Truck Stop Girl". Byrds. [Untitled] lp. https://youtu.be/fdI83TNKdX4?si=JWPrSMCHEX5G1zi9 Georgia Dobbins, William Garrett, Freddie Gorman, …
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Immune Cell Biochemistry I. T lymphocyte Membrane Biochemistry c.8. 20April 2024.Authentic Biochemistry Podcast. Dr. Daniel J. Guerra.
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References Dev Cell. 2016 Jul 25; 38(2): 161–169. J Biol Chem. 2010 Jul 16; 285(29): 22328–22337 Landes Bioscience; 2000-2013.Madame Curie Bioscience Database [Internet]. https://www.ncbi.nlm.nih.gov/books/NBK6207/ Nat Med. 2003 Aug;9(8):1020-5 National Center for Biotechnology Information (2024). PubChem Compound Summary for CID 107970, Fingolimod…
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Immune Cell Biochemistry I. T lymphocyte Membrane Biochemistry. c.7. .18April 2024.Authentic Biochemistry Podcast. Dr. Daniel J. Guerra
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References Proc Natl Acad Sci U S A. 2015 Jul 14; 112(28): 8661–8666 J Exp Med. 2021 Nov 1; 218(11): e20210417 J Biol Chem. 2010 Jul 16; 285(29): 22328–22337. Brahms. J. 1879. Violin Concerto D. Major. OP 77. https://youtu.be/9L6a-JJCCzw?si=r7IAjxBC8ZBfDOaR McCartney/Lennon.1967. "She's Leaving Home" on [Beatles] SPLHCB lp. https://youtu.be/VaBPY78…
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Immune Cell Biochemistry I. T lymphocyte Membrane Biochemistry c.6. 17April 2024.Authentic Biochemistry Podcast.Dr. Daniel J. Guerra.
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References Cold Spring Harb Perspect Med. 2020 Jun; 10(6): a034819 Proc Natl Acad Sci U S A. 2015 Jul 14; 112(28): 8661–8666 Blood. 2010 Jul 22; 116(3): 485–494. Haydn, FJ. 1793. Symphony No 101 D major "Die Uhr“. https://youtu.be/jK9EPZ3qdgU?si=GiCVxNOchDW0fKsb Croce, J. 1970. "Time in a Bottle". https://youtu.be/9h1davKgBYM?si=YhyPwAtno04oYBks --…
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T lymphocyte Membrane Biochemistry I. Immune Cell Biochemistry I c.5 Authentic Biochemistry 16April2024 Dr Daniel J. Guerra
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References Front. Immunol., 2022 Sec. Microbial Immunology Volume 12 Blood 2010. Volume 115, Issue 18, 6 May: 3708-3717 Seeger, P. 1959 . Performed by The Byrds "Turn Turn Turn" https://youtu.be/W4ga_M5Zdn4?si=ODKk_snS-5XHZvWP Copland, A. 1944. "Appalachian Spring. https://youtu.be/CJYVH_kZkOk?si=UUBet58ETg0PVUrB --- Send in a voice message: https:…
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Immune Cell Biochemistry I. T lymphocyte Membrane Biochemistry c.4. 15April 2024. Chemokine gradients and the membrane lipid raft. Authentic Biochemistry Podcast Dr. Daniel J. Guerra
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References FEBS J. 2018 Aug; 285(16): 2944–2971. Nature Reviews Immunology 2023. volume 23, pages 236–250. Angiogenesis. 2021; 24(4): 719–753. Front. Immunol. 2022 Sec. Microbial Immunology Volume 12 Camp, H. 1964. "Pride of Man". performed by Quicksilver Messenger Service. https://youtu.be/fG6A6G9uzsQ?si=tKMdQMVbpTn2x85D --- Send in a voice messag…
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Immune Cell Biochemistry I. T lymphocyte Membrane Biochemistry c.3. 14 April 2024 .Authentic Biochemistry Podcast.Dr. Daniel J. Guerra
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References Nat Rev Gastroenterol Hepatol. 2022 Jun;19(6):351-366 Drugs. 2016 Jul;76(11):1067-79. Front Immunol. 2021; 12: 613591 J Appl Microbiol. 2009. Jun;106(6):1908-18 Exp Cell Res. 2015 May 1; 333(2): 195–200. Mediators Inflamm. 2017; 2017: 4806541. Parsons, G. McQuinn,R. 1971. Pale Blue [ Byrds] Byrdmaniax lp. https://youtu.be/Mh3J7GqrdzY?si=…
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Immune Cell Biochemistry I.T lymphocyte Membrane Biochemistry c.2 Lipid mespmorph and radius assymetry direct Tcell membrane sterol and protein interdigitation that is altered by pressure via PV=nRT.
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References and simple equations PV = nRT where P is pressure (in atm), V isvolume (in liters), n is number of moles and T is temperature (in K); R is a constant and is equal to 0.08206 L atm/moleK. Molecular Shape including thickness(radius) of membrane curvature is v/al where v=volume,a=area per headgroup, and l=thickness of the hydrocarbon monola…
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Immune Cell Biochemistry I.T lymphocyte Membrane Biochemistry c.1. DJGPhD.11April24.Authentic Biochemistry Podcast
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References Front Immunol . 2021 Mar 10:12:613591. Guerra, D. 2020's. Membrane Biochemistry Lectures Crosby, D., Kantner, P., and Stills, S. 1968. "Wooden Ships" [Jefferson Airplane ] from Volunteers lp. https://youtu.be/ROBaoiJK0wc?si=ABsxa4m4AjjAwoms Mendelsshon, F. 1830. "The Hebrides Overture"-Fingal's Cave.OP26. https://youtu.be/MdQyN7MYSN8?si=…
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Biochemical Mosaic III. Coda. DJGPhD .09April24.Authentic Biochemistry Podcast
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References Guerra, D. 2024. The Mosaics I-III. https://podcasts.apple.com/us/podcast/authentic-biochemistry/id1454408625 Beethoven, LV. 1806. Violin Concerto D Major. Op 61. https://youtu.be/cokCgWPRZPg?si=pKKUsINChgI14PH9 --- Send in a voice message: https://podcasters.spotify.com/pod/show/dr-daniel-j-guerra/messageSupport this podcast: https://po…
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Biochemical Mosaic III. c.14. From physical chemistry to the mechanisms of sphingomyelinase mediated inflammation: abrief dialectical accounting of research involving abiotic vs biological phenomena.
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References Guerra, D. 2024. Previous Lectures: Authentic Biochemistry. https://podcasts.apple.com/us/podcast/authentic-biochemistry/id1454408625 Waters, R.1973. "Eclipse" from [Dark Side of the Moon]; Pink Floyd lp. https://youtu.be/k0xGxnZFNYs?si=VrfYPQuXef41Drfm Holst, G. 1918. "The Planets" https://youtu.be/HP5xhyPn58U?si=IdN_iqJNvt_tjQKP --- Se…
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Biochemical Mosaic III.c.13. A priori intralocution of inflammasome genomic loci with stress phenomena immunoepigenetically resolves defensive inflammation. DJGPhD.6April24. Authentic Biochemistry.
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References Guerra, D. 2024 Previous Mosaic III lectures and content. https://podcasts.apple.com/us/podcast/authentic-biochemistry/id1454408625 Hayward, J. 1969. "Never Comes the Day" from Moody Blues lp. Threshold of a Dream. https://youtu.be/8u1zH11yqFQ?si=xtXp1SWm8rF1RdFS Mozart, WA.1785. String Quartet No. 19 in C Major, K. 465 https://youtu.be/…
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Biochemical Mosaic III. c12. A prolegomena to any future biochemical Instanence. Dr Daniel J. Guerra. 4April2024. Authentic Biochemistry Podcast
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Refernces Guerra, DJ. Inclusive non-extemporaneous reasoning on biochemical event ontologies. Jefferson, Blind Lemon 1927, Hunter-Garcia 1969 Jefferson's "I know You Rider" and "China Cat Sunflower" . Grateful Dead. Europe 72' LP. https://youtu.be/xCgZxrf8nrU?si=k7WGmY-fo_AjEip- Schmelzer, JH 1664. Violin Sonatas, "Romanesca". https://youtu.be/fB8G…
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Biochemical Mosaic III. Inflamasomes c.11 A Dialectical Event Ontological conciliantus contrarion perspective.DJGPhD.3April24.Authentic Biochemistry Podcast.
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REferences Guerra, DJ. 2024. Biochemical Mosaic III lectures. https://podcasts.apple.com/us/podcast/authentic-biochemistry/id1454408625 Dvorak, A. 1879. Romance in F minor, Op. 11, (B. 39). https://youtu.be/XZTeavJ9frA?si=18LFzAQ9FKfrQ_16 Dylan, R. 1975. "Tangled up in Blue" performed by Gerry Garcia Band (live;1977) https://youtu.be/8Aw7FW1Frjs?si…
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Biochemical Mosaic III.c.10 Atherogenesis and neointma formation are associated with sphingomyelinase membrane raft NOX aggregation during inflammasome activation.DJGPhD.2April24
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References J Lipid Res. 2022 Dec; 63(12): 100298. Mol Cells. 2020 Aug 31; 43(8): 749–762. Bach J.S. 1727. St Matthew Passion, BWV 244. https://www.youtube.com/live/3fP-rET0kFI?si=ZX-edMPg1wBA_5mh Squire, Chris. 1978. "You Can Be Saved" Yes. https://youtu.be/0TNzPHoVlz8?si=bFMp6w4T2SL6XxS4 --- Send in a voice message: https://podcasters.spotify.com/…
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Biochemical Mosaic III.c.9 Clinical associations of inflammasome mediated pathophysiology linked to epigenetic methylation patterning and DNA repair. DJGPhD.1April24.
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References Redox Biol. 2020 Apr; 31: 101482 Nat Rev Microbiol. 2009 Feb; 7(2): 99–109. J Neuroinflammation. 2019; 16: 236. Front Pharmacol. 2021; 12: 643254. Biber, H. 1676. "Passagalia" por solo violin https://youtu.be/sgcR183f8gA?si=ovfSbdg6WsfuIiTw McBroom, A. 1976. "The Rose" Conway Twitty https://youtu.be/cO59ITNCxzk?si=ueMmXtzMNH4YeQ_w Hunter…
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Biochemical Mosaic III.c.8. S. aureus clearance via dual pyroptosis and necroptosis salientsand the control over the hyperinflammatory axis of clinical disease. DJGPhD.31.3.24
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References Cell Reports 2016.Volume 16, Issue 8, 23 Pages 2219-2230 Front Immunol. 2020; 11: 621733 Proc Natl Acad Sci U S A. 2017 Feb 7;114(6):E961-E969 --- Send in a voice message: https://podcasters.spotify.com/pod/show/dr-daniel-j-guerra/messageSupport this podcast: https://podcasters.spotify.com/pod/show/dr-daniel-j-guerra/support…
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Biochemical Mosaic III.c.7 Convergence of Inflammasome molecular patterning obtains PRR-like sequalae that are hypo-modified epigenetically in multple Human pathophysiologies
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References Int J Mol Sci. 2021 Jul; 22(14): 7580. Trends Biochem Sci. 2023 Apr;48(4):331-344 Immunology. 2020;159:142–155 Curr. Opin. Immunol. 2020;62:39–44. Nat. Rev. Mol. Cell Biol. 2019;20:569–570. Lennon-McCartney. 1963. "This Boy" https://youtu.be/lW5D7HpYhBU?si=mHyiFng3rd3pukob Lennon-McCartney.1966. "And your Bird Can Sing" https://youtu.be/…
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Biochemical Mosaic III. c.6. S auereus induced inflammasome activating pyroptosis circumvents immune clearance and ARDS pulmonary chronic activation share similar hyperinflammatory presentation.DJGPhD
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References Front Immunol. 2019; 10: 1309 Immunity. 2018 Sep 18; 49(3):413–426.e5. Front Immunol. 2020; 11: 621733 Infect Immun. 2013 Dec; 81(12): 4478–4489. Immunity. 2023 Nov 14;56(11):2523-2541.e8. Harrison, G. 1969. "Here Comes the Sun" Abbey Road Lp. Beatles https://youtu.be/GKdl-GCsNJ0?si=xUqwi3Q7Ne694ruD Mozart, WA. 1775. Violin Concerto No.3…
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Biochemical Mosaic III. c.5. Gal3 and NRLP3 inflammasome coordinate inflammation via IL-1Beta convertase activation that is associated with NAFLD and NASH and inhibition of ABCA1 cholesterol efflux.
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References Infect Immun. 2013 Dec; 81(12): 4478–4489 Cell Cycle. 2022; 21(11): 1121–1139. The Journal of Nutritional Biochem.2023.Volume 112, 109217 Lightfoot, G. 1964. "Early Morning Rain" https://youtu.be/ZFJ5Bj_put0?si=m1Ue7rFfk_ggSLR3 Simon ,P. 1968. "Old Friends" SImon and Garfunkle Bookends LP. https://youtu.be/7A76lTte8qE?si=rfk3Q6wTA6Nsiok7…
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