Paradromics Founder and CEO Matt Angle hosts an informal salon with some of the most influential figures in neurotechnology.
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A Grey Matter is for anyone who has ever wondered how we think, feel, reason and move. The Queensland Brain Institute's neuroscience podcast unlocks the wonders of the brain – the complex and mysterious core of who we are. QBI, at The University of Queensland, works to understand the development, organisation and function of the brain. www.qbi.uq.edu.au
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Last year, neuroengineer Dr Clarissa Whitmore joined the Queensland Brain Institute as a senior research fellow and is the Institute’s newest group leader. Originally from the United States, Clarissa arrived at UQ following a postdoctoral appointment at the Max Dellbruck Center for Molecular Medicine in Berlin. In a joint appointment with UQ’s Scho…
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As a Research Fellow in Neuroeconomics, Dr Dragan Rangelov investigates human sensory perception, decision-making and memory. His work explores how the brain processes and stores information that leads us to make decisions in all aspects of life. He does this by using techniques designed to measure and record brain activity, such as electroencephal…
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Robyn Hilton and Allison Scifleet may never have become firm friends had it not been for their involvement in fundraising for dementia research. Both women understand what it is like to care for a loved one with dementia. With more than 421,000 Australians living with dementia and no cure (yet), Robyn and Allison are determined to raise awareness i…
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Reflecting on 20 years of brain research excellence
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What inspired the creation of the Queensland Brain Institute (QBI)? And how did QBI become one of the leading neuroscience research centres in the world? On our 20th anniversary, QBI’s inaugural Director, Emeritus Professor Perry Bartlett, and its current Executive Director, Professor Pankaj Sah, take us back to 2003, an exciting and optimistic tim…
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Hijacking the brain’s intrinsic recovery mechanisms to improve stroke therapies
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Stroke is one of Australia’s biggest killers, with more than 445,000 Australians living with its impacts. Stroke is common, is not always preventable and can happen to anyone at any age. QBI’s Dr Matilde Balbi and her team combine multiple approaches, including in vivo imaging, brain stimulation and AI-driven, individually tailored recovery paradig…
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Understanding epilepsy's electrical storm in the brain
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QBI researcher Dr Nela Durisic is fascinated with how the brain coordinates electrical activity and how faulty electrical communication can lead to brain disorders like epilepsy. By observing the architecture and function of single molecules and their intricate connections, the Durisic lab aims to discover what leads to genetic epilepsy and uncover…
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What we can see inside our brain cells with super-resolution microscopy
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QBI researcher Professor Frederic Meunier is passionate about using highly innovative technology to discover how our brain cells communicate. His lab uses advanced nanoscale imaging (super-resolution microscopy) to observe single molecules in living neurons as they perform their function. In collaboration with mathematicians, the Meunier lab is ana…
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In the fight to find a cure for motor neurone disease
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Boots, beanies and all, QBI researcher Dr Adam Walker is in the fight to find a cure for motor neurone disease (MND). His team uses genetic editing techniques and rapidly advancing technology to study what’s happening at the early onset of disease. By understanding the biological processes that cause MND, they hope to design new therapies that prev…
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How does a teenager’s brain assess risk in decision-making?
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How do we make choices? And what happens in our brain when we do? Cognitive Neuroscientist Professor Jason Mattingley and his team study human brain activity and structure and how people pay attention, prioritise information and decide. With adolescence being a time of great change, the team is fascinated with how young people assess risk and devel…
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What interneurons and their connections can teach us about autism
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Dr Nathalie Dehorter and her team study interneurons (the neurons controlling the excitation-inhibition balance in the central nervous system) during brain development and in disorders like autism, schizophrenia and Parkinson’s disease. Nathalie aims to identify early changes in neuronal activity and connectivity that give rise to impairment in the…
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The many factors that impact how our memory works
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Professor Peter Nestor is a clinician-researcher interested in memory and cognition. As a doctor, he diagnoses people living with neurodegenerative diseases, such as Alzheimer's. By studying patients, he hopes to enhance our understanding of the brain areas most vulnerable to neurodegeneration to improve diagnosis and therapies. In this fascinating…
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How you can build new brain cells even as you age
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Exercise has many benefits for our bodies, including our brains. So, can we replicate the positive effects of exercise to boost new neurons in the adult brain? Dr Tara Walker thinks so and has dedicated her research career to discovering how. Tara was one of the first researchers recruited to QBI when it opened in 2003. She swapped plant biotechnol…
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Perception is a balance between prediction and surprise
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QBI researcher Dr Margaret Moore discusses the fascinating and dynamic process of paying attention. Amidst the sensory overload around us, the brain takes as many shortcuts as possible to process information. To save energy, the brain efficiently chooses to process only what it expects is most helpful, most relevant, and most important to us. It al…
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Exploring new territory in RNA and neuroscience
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QBI researcher Professor Tim Bredy believes his team are on the verge of something big. They are studying the role of ribonucleic acid (RNA), which is present in all living things, including viruses. RNA is structurally like DNA but it is involved in multiple functions, including brain development, learning and memory. In this conversation, Tim exp…
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Your Future Self Will Thank You | Connectomics Part II
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We’re back with Part II of our two-part series on Connectomics! In part one we speculated on the legal and ethical implications of emerging technologies in the connectomics field. In part two, we don our lab coats and take a deep dive into the latest research tools, from fixation protocols for the preservation of neural tissue, to multimodal imagin…
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How sleep helps us learn and respond to the world
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Ever wondered what’s happening in your brain while you sleep and why you need sleep? QBI researchers Professor Bruno van Swinderen and Dr Sally Staton approach sleep from different ends of the scientific spectrum, but both are fascinated by how sleep helps us learn and respond to the world. In this conversation, they delve into thought-provoking t…
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We're in Heated Agreement Over Here | Connectomics Part I
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Welcome back to Neurotech Pub! In this first installment of two episodes on Connectomics, host and Paradromics CEO Matt Angle kicks off a lively discussion on the rapidly accelerating research in the mapping, preservation, and reconstruction of the human connectome. We explore the ethical and legal ramifications of disruptive technology, and some o…
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Looking back on 10 years with Sallyanne Atkinson AO and Professor Perry Bartlett AO
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This episode features an insightful conversation between Sallyanne Atkinson AO, former Lord Mayor of Brisbane and current member of the QBI advisory, and Professor Emeritus Perry Bartlett AO, founding Director of the Queensland Brain Institute (QBI) . You'll hear about the origins of the Clem Jones Centre for Ageing Dementia Research (CJCADR), the …
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Welcome back to Neurotech Pub! In this episode we’re talking about sleep–why we sleep, how sleep works on a neurophysiological level, and some of the emerging sleep technologies that are about to revolutionize this essential neural activity. Our guests are Amy Kruse, PhD, General Partner at Prime Movers Lab, Ram Gurumoorthy, PhD, Founder and CTO of…
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The Panel: Jan Scheuermann is an author and public speaker, and self-styled “professional lab rat.” She has spoken at DARPA, the Johns Hopkins Applied Physics Laboratory, and the National Convention of the ALS Association about her experience as a BCI trial participant at UPitt. She is the author of a fictional mystery novel, Sharp as a Cucumber, a…
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In this very special two part series in collaboration with Blackrock Neurotech, Paradromics CEO Matt Angle and Blackrock Creative Director Taryn Southern co-host a discussion with BCI research pioneers Jan Scheuermann, Ian Burkhart, and Nathan Copeland. In part one, we discuss their personal journeys to becoming BCI pioneers, implant experiences wi…
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Mind Control with Lasers: Optical Recording Part II
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Welcome back to Neurotech Pub! This episode is part two of a two part series on optical methods for recording and stimulating neural activity. Our guests on this episode are Elizabeth Hillman, PhD, Mark Schnitzer, PhD, and Jacob Robinson, PhD. Last time we talked about optical recording methods, but in this episode we focus on optical stimulation m…
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Podcast: Deep brain stimulation - a pacemaker for the brain?
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You probably have heard of a pacemaker – a small device which is implanted in the chest to help control the heartbeat for people living with heart conditions. But did you know similar technology is being used to treat several brain disorders? Today we are joined by Professor Peter Silburn AM, neurologist, researcher and pioneer in deep brain stimul…
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Let there be Light: Optical Recording Part I
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Welcome back to Neurotech Pub! This episode is one of a two part series on optical methods for recording and stimulating neural activity. Our guests on this episode are Elizabeth Hillman, PhD, Mark Schnitzer, PhD, and Jacob Robinson, PhD. So far, our technical dives have focused mainly on direct electrical recording and stimulation of neural activi…
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In recent years, we’ve seen a growing number of sportspeople speak out about their experiences of head injuries, and concussions are forcing more and more athletes to take a break from or cut short their sporting careers. And research on the brains of former athletes is raising awareness of the long-term neurological damage that can be caused by re…
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The link between sleep apnoea and dementia
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People living with dementia often have disturbed sleep – even years prior to experiencing any other symptoms. Unfortunately, as is the case with many risk factors, we don’t know whether this is a cause or a symptom, and it could in fact be both. Professor Elizabeth Coulson specialises in dementia research here at the Queensland Brain Institute and …
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Welcome back to the Season 2 premiere of Neurotech Pub! In this episode, host and Paradromics CEO Matt Angle sits down with fellow Founder/CEOs Carolina Aguilar, Brian Pepin, and Kunal Ghosh to talk shop about building cutting edge neurotech companies from the ground up. We dive deep into business strategies, the neurotech fundraising landscape, em…
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The development of the brain is a fascinating process, with complex brain connections being made rapidly as a foetus grows inside its mother’s womb.Darryl Eyles, Professor of neurobiology, is studying how known risk factors for certain mental disorders can change the way the brain develops.In this episode we explore how the developing brain can ada…
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Mini brains and the potential of organoids
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How can you study the human brain at the cell level, when you can't get inside to see these tiny processes in action? Well, you build your own brain in a dish of course! Organoids, or mini brains, are an exciting new area of neuroscience an have many applications, including personalised medicine. We talk to Professor Enrst Wolvetang, who's using th…
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In this episode, we examine consciousness – what is it, when does it begin, and how might sleep and dreams be the key to answering these questions. Professor Bruno van Swinderen sheds more light on this fascinating topic.By Professor Bruno van Swinderen
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When neuroscience meets conservation science
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Queensland Chief Scientist, Professor Hugh Possingham and Queensland Brain Institute Director, Professor Pankaj Sah talk about the lessons we can learn from conservation science and neuroscience, how to influence decision-makers, and why maths is so important! CREDITS Produced, hosted and edited by Carolyn Barry…
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Pay attention! How your brain decides what to focus on
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When we pay attention to something, our minds are selectively concentrating on a discrete piece of information, while choosing to ignore other perceivable elements. Dr Anthony Harris is an ARC Discovery Early Career Researcher Award Fellow at the Queensland Brain Institute and an expert on human attention. He discusses what goes on in the brain whe…
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Almost 500,000 Australians have some kind of dementia, the most common form of which is Alzheimer’s disease. Currently, there is no cure, and only one drug was recently approved for treatment. Researchers here at the Queensland Brain Institute are working on an ultrasound treatment that may offer the best chance to hit the damaged neurons and slow …
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Building (and Funding) Neurotech Companies
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Welcome to the Season 1 finale of Neurotech Pub! In this episode, host and Paradromics CEO, Matt Angle, speaks with fellow Neurotech CEOs, Konstantinos Alataris, Frank Fischer, and Marcus Gerhardt. "We cover a lot in this discussion, but one of the big themes is how challenging it can be to raise money, to build neuro devices. This episode was orig…
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The Drinks Bring Back All The Memories
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Welcome back to Neurotech Pub! In this episode, host and Paradromics CEO, Matt Angle, brings together memory-researchers Nanthia Suthana (Assist. Prof. of Neurosurgery and Bioengineering, UCLA School of Medicine) and Gyorgy Buzsaki (Biggs Professor of Neuroscience, NYU School of Medicine), and scientist-entrepreneurs Dan Rizzuto (CEO of Nia Therape…
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Artist Sam Leach’s work focuses on a connection between science and art, in a more modern twist. He uses AI to compose art that he then paints. It’s a blending of two fields in a similar way that researchers are blending machine learning and neuroscience, to push the limits of AI. We talk also talk to neuroscientist Emeritus Professor Srini Sriniva…
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Where psychology and neuroscience collide
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How do you make sure clinical treatment of people with brain injury, diseases and disorders is best informed by neuroscience? This is where the worlds of neuroscience and psychology collide. In this episode, we talk to Professor Gail Robinson, clinical neurospsychologist at the Queensland Brain Institute.…
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Neurotechnology Startups and the E Word
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Welcome back to Neurotech Pub! In this episode, host and Paradromics CEO, Matt Angle, brings together Karen Rommelfanger (Neurotech Ethicist, Strategist, and Associate Professor at Emory), Anna Wexler (Assistant Professor of Medical Ethics and Health Policy at UPenn), Ana Maiques (CEO of Neuroelectrics), and Stephanie Naufel Thacker (Technical Prog…
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Welcome back to Neurotech Pub! In this episode, host and Paradromics CEO, Matt Angle, discusses the science of olfaction with Andreas Schaefer, Gabe Lavella, and Dima Rinberg. Gabe and Dima also unveil their new startup, Canaery, which uses BCI-enhanced animals to digitize the olfactory world. Check out full video with transcript here: https://www.…
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A Lawyer, a Philosopher, and Two Neurologists Walk Into a Bar…
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Welcome back to Neurotech Pub! In this episode, host and Paradromics CEO, Matt Angle, discusses ethical considerations around brain-computer interfaces. Our guests are Tim Brown, Leigh Hochberg, Sydney Cash, and Amanda Pustilnik. A central theme in the discussions will be how neuroethics differ from traditional medical ethics or bioethics and what …
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Trading Spaces // Dimensionality Reduction for Neural Recordings
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Welcome back to Neurotech Pub! In this episode, Vikash Gilja reprises his role as Vikash Gilja. We are also joined by Konrad Kording, Chethan Pandarinath, and Carsen Stringer. We talk about how dimensionality reduction is used to better understand large scale neural recordings. This episode is fairly technical, but it contains many great references…
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Paralysed people walking again and direct brain to brain communication aren’t just ideas in the realm of science fiction. We hear from Dr Lilach Avitan, a Computational Neuroscientist at UQ’s Queensland Brain Institute who investigates how our brain processes information in order to understand normal and abnormal brain function. We chat about her s…
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Welcome back to Neurotech Pub! In this episode, host and Paradromics CEO, Matt Angle, speaks with Stuart Cogan, Vanessa Tolosa, Thomas Stieglitz, and Loren Rieth about how to protect neural implants from the harsh environment of the body. This discussion is all about longevity and endurance, and, fittingly, it’s almost 2 hours long. Loren leaves ea…
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What We’ve Got Here Is Failure To Communicate
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Welcome back to Neurotech Pub! In this episode, host and Paradromics CEO, Matt Angle, speaks with Beata Jarosiewicz, Vikash Gilja, Sergey Stavisky, and Frank Willett about how brain computer interfaces can be used to restore communication in patients with tetraplegia. They take a deep dive into state of the art thought-to-text technology compared w…
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Welcome to Neurotech Pub, hosted by Paradromics Inc and SynBioBeta. In this episode, host and Paradromics CEO, Matt Angle, speaks with Tim Harris, Cindy Chestek, and Philip "Flip" Sabes about the big programmatic challenges in neurotechnology. We talk about the differences between labs, startups, and large research consortia. We discuss the differe…
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What did one brain cell say to the other?
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The brain is one of the most complex things that scientists study, with trillions of connections between brain cells responsible for our thoughts and actions and baseline functions. You’d think that if you zoom down and look into the cells and how they talk to each other, that things would be simpler but that’s not the case. Down at the nanoscale l…
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The neurological effects of COVID-19 and why we lose smell
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More and more we are finding out about the peculiar symptoms of coronavirus that make it such a nasty bug. Many of these symptoms, especially those with a long tail of illness seem to point to effects on the nervous system: the loss of smell, dizziness, confusion, strokes, muscle weakness, fatigue. New research born out of collaborations with virol…
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Did you know? Humans are pretty average when it comes to seeing the visual world compared to many other animals with much smaller brains. Or that octopuses are essentially colourblind? And that there’s really no such thing as colour?We talk to visual ecologist Professor Justin Marshall about the fascinating world of animal vision. CREDIT Hosted, pr…
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From stem cells, billions of brain cells grow
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At the very earliest stages of life, how do stem cells know how to turn into the right cells at the right time and go to the right places. Just a few cells create the billions of brain cells we have. In this episode, we talk to Professor Helen Cooper, Deputy Director of Research at the Queensland Brain Institute. She studies the complex world of th…
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How do birds and bees fly in groups without colliding? or know how to navigate straight to a food source? And how do you train a bee to fly down a tunnel? Studying these tiny insects can give us insight, not only into how our brains work, but also how we might enhance aircraft navigation. CREDIT Hosted by Donna Lu, edited by Carolyn Barry…
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