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Blunted response to rewards in preschoolers with depression

 
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Archived series ("Inactive feed" status)

When? This feed was archived on January 20, 2022 04:34 (2y ago). Last successful fetch was on April 07, 2020 16:45 (4y ago)

Why? Inactive feed status. Our servers were unable to retrieve a valid podcast feed for a sustained period.

What now? You might be able to find a more up-to-date version using the search function. This series will no longer be checked for updates. If you believe this to be in error, please check if the publisher's feed link below is valid and contact support to request the feed be restored or if you have any other concerns about this.

Manage episode 167986575 series 1299386
Content provided by Washington University School of Medicine in St. Louis and Jim Dryden. All podcast content including episodes, graphics, and podcast descriptions are uploaded and provided directly by Washington University School of Medicine in St. Louis and Jim Dryden or their podcast platform partner. If you believe someone is using your copyrighted work without your permission, you can follow the process outlined here https://player.fm/legal.

Adults and teenagers with clinical depression don’t respond to rewards in a normal manner. Their moods are less enthusiastic, and their brains don’t act the same way as those in adults and adolescents who are not depressed. Although depression has been diagnosed in children as young as 3, it hasn’t been clear whether the responses of very young children to rewards also may be blunted. So Washington University researchers studied kids ages 4 to 7 and found that, like adults, when these young children were depressed, their brains were less likely to respond to rewards. The researchers say that could mean insensitivity to rewards may serve as a “red flag” for depression in young children.

PAST RESEARCH HAS FOUND THAT THE BRAINS OF DEPRESSED ADULTS AND ADOLESCENTS OFTEN DON’T RESPOND AS MUCH TO REWARDS AS THE BRAINS OF PEOPLE WHO DON’T HAVE DEPRESSION. NOW, CHILD PSYCHIATRY RESEARCHERS AT WASHINGTON UNIVERSITY SCHOOL OF MEDICINE IN ST. LOUIS HAVE FOUND THE SAME THING IS TRUE IN VERY YOUNG CHILDREN. JIM DRYDEN HAS MORE…

IT’S GETTING TO BE THE SEASON FOR PRESENTS, AND IF YOUR FOUR-YEAR-OLD DOESN’T SEEM EXCITED ABOUT THAT, IT COULD BE A PROBLEM ACCORDING TO RESEARCHERS AT WASHINGTON UNIVERSITY SCHOOL OF MEDICINE IN ST. LOUIS. IN OLDER ADOLESCENTS AND ADULTS, RESEARCH HAS FOUND THAT WHEN A PERSON IS DEPRESSED, THE BRAIN’S RESPONSE TO REWARDS CAN BE BLUNTED. NOW, THE FIRST AUTHOR OF A NEW STUDY OF PRESCHOOLERS SAYS THEY’VE FOUND THE SAME THING IS TRUE IN KIDS AS YOUNG AS FOUR. ANDREW BELDEN SAYS THIS IS…

(act) :14 o/c age-appropriate tasks

…frequently found in adults and adolescents, so what we were

interested in doing was to see, do, in fact, the depressed

preschoolers show this blunted response to reward doing slightly

modified, but age-appropriate tasks?

AGE-APPROPRIATE TASKS BECAUSE THE CHILDREN WERE PLAYING FOR TOYS. ADULTS AND ADOLESCENTS WERE STUDIED USING MONEY AS A REWARD. BELDEN SAYS FOR THIS STUDY, KIDS WERE SHOWN A COUPLE OF SETS OF TOYS THAT THEY COULD WIN. THEN THEY SAT AT A COMPUTER AND WERE ASKED TO PICK ONE OF TWO DOORS, WHICH THEN RANDOMLY GAVE THEM POINTS TOWARD A GOOD TOY OR SUBTRACTED POINTS FROM THEM, KIND OF LIKE A SLOT MACHINE FOR PRESCHOOLERS.

(act) :08 o/c adolescents, adults

The depressed preschoolers show a neural response very similar

to what is seen in older children, adolescents, adults.

THE RESEARCHERS MEASURED BRAIN ACTIVITY BY HAVING THE KIDS WEAR A SHOWER CAP-LOOKING DEVICE THAT WAS HOOKED TO ELECTRODES THAT MONITORED THEIR BRAIN ACTIVITY AS THE CHILDREN MADE CHOICES AND LEARNED WHETHER THOSE CHOICES WERE GETTING THEM CLOSER TO A TOY THEY LIKED, OR FARTHER AWAY. SENIOR INVESTIGATOR JOAN LUBY SAYS HER RESEARCH PREVIOUSLY HAD IDENTIFIED ANHEDONIA, THAT IS AN INABILITY TO EXPERIENCE JOY, FOR EXAMPLE IN ACTIVITIES AND PLAY, AS AN IMPORTANT MARKER OF DEPRESSION IN PRESCHOOLERS. AND THESE NEW FINDINGS APPEAR TO FIT WITH THOSE OLDER ONES.

(act) :17 o/c rewarding tasks

So this just gave us the neural validator of the behavior. An

alteration in this process this early in development is a serious

concern because it sort of sets the stage for how people approach

their interaction with rewarding tasks.

AND BELDEN SAYS THE DIFFERENCES WEREN’T APPARENT WHEN THE CHILDREN MADE A CHOICE THAT COST THEM POINTS. IN OTHER WORDS, IT WASN’T THAT THE BRAIN REACTED MORE NEGATIVELY TO FAILURE. IT WAS THAT IT REACTED LESS POSITIVELY TO SUCCESS AND REWARD.

(act) :06 o/c or reward

The difference was specific to their reactivity, their neural

reaction, to winning, or reward.

LUBY AND BELDEN ARE CONTINUING TO STUDY PRESCHOOLERS WITH AND WITHOUT DEPRESSION. THEY SAY THEY PLAN TO USE MRI IMAGING TO LOOK MORE CLOSELY AT SPECIFIC BRAIN REGIONS THAT MAY BE RESPONSIBLE FOR THE DIFFERENCES THEY SAW IN THIS STUDY, AND LUBY SAYS THE RESEARCHERS ALSO PLAN TO SEE WHETHER THERAPY MIGHT CHANGE THESE PATTERNS.

(act) :06 o/c the treatment

With the expectation that they will have a greater response to

reward after undergoing the treatment.

LUBY, BELDEN AND THEIR COLLEAGUES REPORT THEIR FINDINGS IN THE JOURNAL OF THE AMERICAN ACADEMY OF CHILD & ADOLESCENT PSYCHIATRY. I’M JIM DRYDEN…

RUNS 3:00

  continue reading

50 episodes

Artwork
iconShare
 

Archived series ("Inactive feed" status)

When? This feed was archived on January 20, 2022 04:34 (2y ago). Last successful fetch was on April 07, 2020 16:45 (4y ago)

Why? Inactive feed status. Our servers were unable to retrieve a valid podcast feed for a sustained period.

What now? You might be able to find a more up-to-date version using the search function. This series will no longer be checked for updates. If you believe this to be in error, please check if the publisher's feed link below is valid and contact support to request the feed be restored or if you have any other concerns about this.

Manage episode 167986575 series 1299386
Content provided by Washington University School of Medicine in St. Louis and Jim Dryden. All podcast content including episodes, graphics, and podcast descriptions are uploaded and provided directly by Washington University School of Medicine in St. Louis and Jim Dryden or their podcast platform partner. If you believe someone is using your copyrighted work without your permission, you can follow the process outlined here https://player.fm/legal.

Adults and teenagers with clinical depression don’t respond to rewards in a normal manner. Their moods are less enthusiastic, and their brains don’t act the same way as those in adults and adolescents who are not depressed. Although depression has been diagnosed in children as young as 3, it hasn’t been clear whether the responses of very young children to rewards also may be blunted. So Washington University researchers studied kids ages 4 to 7 and found that, like adults, when these young children were depressed, their brains were less likely to respond to rewards. The researchers say that could mean insensitivity to rewards may serve as a “red flag” for depression in young children.

PAST RESEARCH HAS FOUND THAT THE BRAINS OF DEPRESSED ADULTS AND ADOLESCENTS OFTEN DON’T RESPOND AS MUCH TO REWARDS AS THE BRAINS OF PEOPLE WHO DON’T HAVE DEPRESSION. NOW, CHILD PSYCHIATRY RESEARCHERS AT WASHINGTON UNIVERSITY SCHOOL OF MEDICINE IN ST. LOUIS HAVE FOUND THE SAME THING IS TRUE IN VERY YOUNG CHILDREN. JIM DRYDEN HAS MORE…

IT’S GETTING TO BE THE SEASON FOR PRESENTS, AND IF YOUR FOUR-YEAR-OLD DOESN’T SEEM EXCITED ABOUT THAT, IT COULD BE A PROBLEM ACCORDING TO RESEARCHERS AT WASHINGTON UNIVERSITY SCHOOL OF MEDICINE IN ST. LOUIS. IN OLDER ADOLESCENTS AND ADULTS, RESEARCH HAS FOUND THAT WHEN A PERSON IS DEPRESSED, THE BRAIN’S RESPONSE TO REWARDS CAN BE BLUNTED. NOW, THE FIRST AUTHOR OF A NEW STUDY OF PRESCHOOLERS SAYS THEY’VE FOUND THE SAME THING IS TRUE IN KIDS AS YOUNG AS FOUR. ANDREW BELDEN SAYS THIS IS…

(act) :14 o/c age-appropriate tasks

…frequently found in adults and adolescents, so what we were

interested in doing was to see, do, in fact, the depressed

preschoolers show this blunted response to reward doing slightly

modified, but age-appropriate tasks?

AGE-APPROPRIATE TASKS BECAUSE THE CHILDREN WERE PLAYING FOR TOYS. ADULTS AND ADOLESCENTS WERE STUDIED USING MONEY AS A REWARD. BELDEN SAYS FOR THIS STUDY, KIDS WERE SHOWN A COUPLE OF SETS OF TOYS THAT THEY COULD WIN. THEN THEY SAT AT A COMPUTER AND WERE ASKED TO PICK ONE OF TWO DOORS, WHICH THEN RANDOMLY GAVE THEM POINTS TOWARD A GOOD TOY OR SUBTRACTED POINTS FROM THEM, KIND OF LIKE A SLOT MACHINE FOR PRESCHOOLERS.

(act) :08 o/c adolescents, adults

The depressed preschoolers show a neural response very similar

to what is seen in older children, adolescents, adults.

THE RESEARCHERS MEASURED BRAIN ACTIVITY BY HAVING THE KIDS WEAR A SHOWER CAP-LOOKING DEVICE THAT WAS HOOKED TO ELECTRODES THAT MONITORED THEIR BRAIN ACTIVITY AS THE CHILDREN MADE CHOICES AND LEARNED WHETHER THOSE CHOICES WERE GETTING THEM CLOSER TO A TOY THEY LIKED, OR FARTHER AWAY. SENIOR INVESTIGATOR JOAN LUBY SAYS HER RESEARCH PREVIOUSLY HAD IDENTIFIED ANHEDONIA, THAT IS AN INABILITY TO EXPERIENCE JOY, FOR EXAMPLE IN ACTIVITIES AND PLAY, AS AN IMPORTANT MARKER OF DEPRESSION IN PRESCHOOLERS. AND THESE NEW FINDINGS APPEAR TO FIT WITH THOSE OLDER ONES.

(act) :17 o/c rewarding tasks

So this just gave us the neural validator of the behavior. An

alteration in this process this early in development is a serious

concern because it sort of sets the stage for how people approach

their interaction with rewarding tasks.

AND BELDEN SAYS THE DIFFERENCES WEREN’T APPARENT WHEN THE CHILDREN MADE A CHOICE THAT COST THEM POINTS. IN OTHER WORDS, IT WASN’T THAT THE BRAIN REACTED MORE NEGATIVELY TO FAILURE. IT WAS THAT IT REACTED LESS POSITIVELY TO SUCCESS AND REWARD.

(act) :06 o/c or reward

The difference was specific to their reactivity, their neural

reaction, to winning, or reward.

LUBY AND BELDEN ARE CONTINUING TO STUDY PRESCHOOLERS WITH AND WITHOUT DEPRESSION. THEY SAY THEY PLAN TO USE MRI IMAGING TO LOOK MORE CLOSELY AT SPECIFIC BRAIN REGIONS THAT MAY BE RESPONSIBLE FOR THE DIFFERENCES THEY SAW IN THIS STUDY, AND LUBY SAYS THE RESEARCHERS ALSO PLAN TO SEE WHETHER THERAPY MIGHT CHANGE THESE PATTERNS.

(act) :06 o/c the treatment

With the expectation that they will have a greater response to

reward after undergoing the treatment.

LUBY, BELDEN AND THEIR COLLEAGUES REPORT THEIR FINDINGS IN THE JOURNAL OF THE AMERICAN ACADEMY OF CHILD & ADOLESCENT PSYCHIATRY. I’M JIM DRYDEN…

RUNS 3:00

  continue reading

50 episodes

All episodes

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