Best A16z Crypto Podcasts (2025)

1
Social Media Secrets: How to Build Your Presence 41:20

24h ago41:20

41:20

with @0xgaut @ishverduzco @rhhackett Welcome to web3 with a16z. Today we’re talking about how to make social media work for you, rather than overwhelming you. Whether you’re a startup founder, creator, avid doomscroller, or longtime lurker, this show has tips and tactics you can use to attract attention, build a following, and level up your online …

1
Crypto Trends for 2025: Stablecoins, App Stores, UX, and More 34:54

11d ago34:54

34:54

with @sambroner @meigga @darenmatsuoka @jneu_net @chrislyons and @rhhackett @smc90 Welcome to our special end-of-year episodes -- which also look ahead to 2025 -- covering our annual Big Ideas lists, where various a16z crypto team members share what they are personally excited about. (You can see the firmwide list, also including all the trends of …

1
Marc Andreessen: Can Tech Finally Fix Healthcare? 32:33

28m ago32:33

32:33

Healthcare is a $4 trillion industry, making up nearly a fifth of the U.S. economy—but despite having some of the best doctors and advanced technology, the system often delivers poor outcomes at skyrocketing costs. Why is this the case, and what will it take to fix it? In this episode, a16z cofounder Marc Andreessen and General Partners Vijay Pande…

1
Building Substack: Reinventing Culture through Subscriptions 36:45

5d ago36:45

36:45

In this episode, Substack cofounder and CEO Chris Best joins a16z General Partner Andrew Chen to discuss the origins and evolution of Substack, a platform redefining media and empowering creators to connect directly with their audiences. They dive into how Substack’s early days led to over 3 million paid subscribers, why creators are moving away fr…

1
Designing Beloved Brands 36:46

15d ago36:46

36:46

Welcome to web3 with a16z. Today's episode is all about design, creativity, and taste-making. Our special guest is Jason Mayden, the chief design officer of Jordan Brand at Nike — that's Jordan as in former NBA superstar Michael Jordan. In his role, Mayden is responsible for the look and feel of iconic products, like Air Jordan sneakers and related…

1
Super Staffing Healthcare, Codifying Compliance, & Scaling Services 52:09

15d ago52:09

52:09

As we prepare to step into 2025, the possibilities for applied AI are reshaping industries in profound ways. In this episode, a16z General Partners Julie Yoo and Angela Strange, and Partner Joe Schmidt, dive into the transformative power of AI across healthcare, fintech, and traditional service sectors. We explore: Super Staffing for Healthcare: Ho…

1
The Race for AI—Search, National Infrastructure, & On-Device AI 42:45

20d ago42:45

42:45

The AI race is on, and 2025 could be its most transformative year yet. In this episode, a16z General Partners Anjney Midha and Jennifer Li, and Partner Alex Immerman dive into the trends reshaping AI and its impact on search, infrastructure, and devices. We explore: How AI-native tools like ChatGPT and Perplexity are challenging Google’s search dom…

1
Trends for 2025 (part 2): AI x Crypto - From Agents in Games & DePIN to Proof of Personhood and More 40:05

24d ago40:05

40:05

with @carrawu @eddylazzarin @0xkarmacoma and @smc90 @rhhackett Welcome to our special end-of-year episodes -- which also look ahead to 2025 -- covering our annual Big Ideas lists, where various a16z crypto team members share what they are personally excited about. (You can see the firmwide list, also including all the trends of the crypto team, her…

1
Trends for 2025 (part 1): Stablecoins, App Stores, UX, and More 33:52

25d ago33:52

33:52

with @sambroner @meigga @darenmatsuoka @jneu_net @chrislyons and @rhhackett @smc90 Welcome to our special end-of-year episodes -- which also look ahead to 2025 -- covering our annual Big Ideas lists, where various a16z crypto team members share what they are personally excited about. (You can see the firmwide list, also including all the trends of …

1
Jobs of the Future, Harnessing Earth Observation, & Gaming Tech Advances 41:59

25d ago41:59

41:59

As 2025 begins, industries are evolving at unprecedented speed: robots are revolutionizing manufacturing, terabytes of earth observation data are driving new possibilities, and gaming technology is transforming how we design, train, and innovate across sectors. In this episode, a16z General Partner Erin Price-Wright, Engineering Fellow Millen Anand…

1
Scaling Shopify: Tobias Lütke and Ben Horowitz on Building a Global Giant 45:26

29d ago45:26

45:26

In this episode of Web3 with a16z, Shopify CEO and cofounder Tobias Lütke joins a16z cofounder Ben Horowitz for a conversation recorded live at the a16z crypto Founders Summit. Together, they explore what it takes to build a breakout startup in a competitive market, the changing landscape of retail, and how to drive workplace change while navigatin…

1
How AI is Transforming Labor Markets 44:38

1M ago44:38

44:38

Did you know the U.S. nurse labor market is over $600 billion annually, but the dedicated software market for nurses is almost zero? In this episode General Partners Alex Rampell, David Haber, and Angela Strange discuss how AI is revolutionizing labor by automating tasks traditionally done by humans. They’ll trace the evolution of cloud eras — from…

1
Fixing Education in America: What's Stopping Us? 40:39

1M ago40:39

40:39

Over half of Americans live in childcare deserts, while 90% of brain development happens before the age of five. All the while, education and childcare remain among the most resistant sectors to technological change. Billions of dollars have been spent, but outcomes continue to lag. Why? In this episode, we dive into the systemic issues—misaligned …

1
Prediction Markets and Beyond 1:49:49

1M ago1:49:49

1:49:49

This episode was originally published on our sister podcast, web3 with a16z. If you’re excited about the next generation of the internet, check out the show: https://link.chtbl.com/hrr_h-XC We've heard a lot about the premise and the promise of prediction markets for a long time, but they finally hit the main stage with the most recent election. So…

1
Death of a Salesforce: Why AI Will Transform Sales 16:34

2M ago16:34

16:34

Sales is evolving. AI-native systems are replacing traditional CRM tools, capturing unstructured insights from emails, Slack, surveys, and more in real time. These systems automate early-stage tasks like prospecting and qualification, enabling sales teams to focus on high-value work—while AI provides live coaching and drives decisions across sales,…

1
Prediction Markets and Beyond 1:48:05

2M ago1:48:05

1:48:05

with @atabarrok @skominers @smc90 We've heard a lot about the premise and the promise of prediction markets for a long time, but they finally hit the main stage with the most recent election. So what worked (and didn't) this time? Are they better than pollsters, journalists, domain experts, superforecasters? So in this conversation, we tease apart …

1
Las Vegas is Becoming America's Safest City 1:12:42

2M ago1:12:42

1:12:42

In this special episode, a16z co-founders Marc Andreessen and Ben Horowitz sit down with Chief Mike Gennaro and Sheriff Kevin McMahill of the Las Vegas Metro Police Department (LVMPD) to discuss how their organization is using advanced technology to become the safest city in America. In a wide-randing conversation, Chief Gennaro and Sheriff McMahil…

1
The Longevity Imperative: Redefining the Way We Age 40:30

2M ago40:30

40:30

What if the biggest challenge of our time isn’t living longer, but living better? In this episode, we’re tackling one of humanity’s greatest accomplishments—and perhaps its most overlooked challenge: longevity. As more people live past 100, our systems—healthcare, finance, career planning, and even our cultural perceptions of aging—need a fundament…

1
Trump is About to Change Everything For Tech Startups 59:40

2M ago59:40

59:40

In this special post-election episode, a16z co-founders Marc Andreessen and Ben Horowitz reflect on Trump's dramatic political victory and its potential impact on the tech industry—particularly in AI, crypto, and defense. They also discuss their new involvement in politics, the importance of bipartisan support and the rightful role of regulation, a…

1
Rebuilding America's Industrial Backbone 32:34

2M ago32:34

32:34

America is a country of immense wealth, but our manufacturing infrastructure is struggling to keep pace. In this episode, we discuss the overlooked crisis of American manufacturing and what it means for our national resilience. a16z’s Oliver Hsu hosts a conversation with founders Jordan Black (Senra Systems), Chris Power (Hadrian), and Bryon Hargis…

1
New AI Policy Update on Safety, Censorship & Unexpected Risks 1:15:32

3M ago1:15:32

1:15:32

In this episode, a16z co-founders Marc Andreessen and Ben Horowitz dive into the latest AI policy updates, emphasizing the need for informed debate on AI’s risks and benefits, and the policies needed for AI startups to thrive and collaborate. This conversation follows a16z's recent joint statement with Microsoft’s Chairman and CEO Satya Nadella and…

1
Autonomy Across Air, Land, and Sea 48:18

3M ago48:18

48:18

2024 has been a milestone year for autonomous tech. Waymo’s fully autonomous driver has surpassed 20 million miles, while FAA approvals now allow commercial drones to fly without visual observers, advancing air autonomy in unprecedented ways. In this special live recording from SF Tech Week, a16z partner Erin Price-Wright moderates a panel of exper…

1
Government... By Lottery? 57:24

2M ago57:24

57:24

with @baileyflan @ahall_research @rhhackett Today we’re dusting off an ancient practice that has become trendy once again: the old-but-new idea of “sortition,” or selecting representatives by lottery. Sortition was used in ancient Athenian democracy to elect public officials. It’s also been lately revived by tech companies like Meta and AI startups…

1
U.S. vs. China: AI, Robotics & the New Global Arms Race 34:14

3M ago34:14

34:14

In this episode, a16z co-founders Marc Andreessen and Ben Horowitz explore the intensifying competition between the U.S. and China in artificial intelligence and robotics, assessing the U.S.'s strengths in software development while raising concerns about China’s growing dominance in hardware (particularly in drone technology). Marc and Ben present…

1
State of Crypto 2024: Builder Energy, U.S. Election, Stablecoins, AI, More 54:19

3M ago54:19

54:19

We take you behind the scenes of our newly released, annual State of Crypto Report — a16z crypto's analysis of the latest data and trends that have defined the industry in 2024. This year's report features some brand new insights, from estimating the number of real crypto users globally, to understanding how much interest in crypto swing states may…

1
AI Bots & Memecoins 38:02

3M ago38:02

38:02

with @pmarca @bhorowitz Today we’re running a special episode featuring a16z cofounders Marc Andreessen and Ben Horowitz talking about AI bots and crypto. They discuss what happens when you mix postmodern theories and internet memes in an LLM. They also get into the sudden rise of a strange memecoin, the state of crypto regulation in the U.S., and …

1
Tesla's Road Ahead: The Bitter Lesson in Robotics 36:46

3M ago36:46

36:46

What does Rich Sutton’s "Bitter Lesson" reveal about the decisions Tesla is making in its pursuit of autonomy? In this episode, we dive into Tesla’s recent "We, Robot" event, where they unveiled bold plans for the unsupervised full-self-driving Cybercab, Robovan, and Optimus—their humanoid robot, which Elon Musk predicts could become “the biggest p…

1
How An AI Bot Became a Crypto Millionaire 37:25

3M ago37:25

37:25

In this episode, a16z co-founders Marc Andreessen and Ben Horowitz explore the fascinating intersection of AI and crypto, highlighting the rise of Truth Terminal (@truth_terminal), an autonomous chatbot developed by AI researcher Andy Ayrey. With its own X account, Truth Terminal generates original and often hilarious content independently. Marc's …

1
The Story of Apple Pay with Jennifer Bailey 31:53

3M ago31:53

31:53

In 2024, marking 10 years since its launch, Apple Pay now boasts hundreds of millions of consumers in 78 markets, at checkout on millions of websites and apps, in tens of millions of stores worldwide, and is supported by more than 11,000 bank and network partners. In this episode, a16z General Partner Alex Rampell sits down with Jennifer Bailey, VP…

1
State of Crypto 2024: Builder Energy, U.S. Election, Stablecoins, AI, More 53:24

3M ago53:24

53:24

with @DarenMatsuoka @eddylazzarin @rhhackett Welcome to web3 with a16z. Today we're taking you behind the scenes of our newly released, annual State of Crypto Report — a16z crypto's analysis of the latest data and trends that have defined the industry in 2024. This year's report features some brand new insights, from estimating the number of real c…

1
Building a Thriving AI Ecosystem with Lisa Su 30:59

3M ago30:59

30:59

Lisa Su has transformed AMD into a global leader in AI and high-performance computing. In this episode of the AI Revolution (AIR) series , Bob Swan, a16z Operating Partner and former CEO of Intel, sits down with Lisa Su, CEO of AMD, to discuss how her leadership has propelled AMD’s growth and positioned the company at the forefront of AI innovation…

1
The Deepfake Dilemma: The Technology, Policy, and Economy 34:59

3M ago34:59

34:59

Deepfakes—AI-generated fake videos and voices—have become a widespread concern across politics, social media, and more. As they become easier to create, the threat grows. But so do the tools to detect them. In this episode, Vijay Balasubramaniyan, cofounder and CEO of Pindrop, joins a16z’s Martin Casado to discuss how deepfakes work, how easily the…

1
A Big Week in Tech: NotebookLM, OpenAI’s Speech API, & Custom Audio 32:01

3M ago32:01

32:01

Last week was another big week in technology. Google’s NotebookLM introduced its Audio Overview feature, enabling users to create customizable podcasts in over 35 languages. OpenAI followed with their real-time speech-to-speech API, making voice integration easier for developers, while Pika’s 1.5 model made waves in the AI world. In this episode, w…

1
From Swipe to Scale: How Tinder Became #1 28:32

4M ago28:32

28:32

In 1995, just 2% of couples met online. Today, that number has surged to over 50%, making online dating the top way couples connect. In this episode, a16z General Partner Andrew Chen chats with Tinder founder Sean Rad about how he built an app that changed culture. Sean shares why seamless experiences matter, how startups often get marketing wrong,…

1
Bridges: Out of the Mess, Into the Meshnet (with LayerZero) 41:43

4M ago41:43

41:43

Welcome to web3 with a16z. Today we explore the messy secrets of blockchain bridges. These cross-chain connectors are the go-betweens in today's multichain world, but their short history has been a checkered one, with prominent projects succumbing to major hacks and other hijinks. So we've brought on one of the builders who knows this world best to…

1
Human Data is Key to AI: Alex Wang from Scale AI 30:56

4M ago30:56

30:56

What if the key to unlocking AI's full potential lies not just in algorithms or compute, but in data? In this episode, a16z General Partner David George sits down with Alex Wang, founder and CEO of Scale AI, to discuss the crucial role of "frontier data" in advancing artificial intelligence. From fueling breakthroughs with complex datasets to navig…

1
The Frontier of Spatial Intelligence with Fei-Fei Li 44:40

4M ago44:40

44:40

Fei-Fei Li and Justin Johnson are pioneers in AI. While the world has only recently witnessed a surge in consumer AI, our guests have long been laying the groundwork for innovations that are transforming industries today. In this episode, a16z General Partner Martin Casado joins Fei-Fei and Justin to explore the journey from early AI winters to the…

1
Apple’s Big Reveals, OpenAI’s Multi-Step Models, and Firefly Does Video 31:55

4M ago31:55

31:55

This week in consumer tech: Apple’s big reveals, OpenAI’s multi-step reasoning, and Adobe Firefly’s video model. Olivia Moore and Justine Moore, Partners on the a16z Consumer team, break down the latest announcements and how these product launches will shape the tech ecosystem, transform AI-powered experiences, and impact startups competing for att…

1
Games as Reality (with EVE Online) 35:59

4M ago35:59

35:59

with @HilmarVeigar @eddylazzarin Our featured guest today is Hilmar Pétursson, the CEO of CCP Games, maker of EVE Online, a massive multiplayer online role playing game. In this episode, Pétursson shares his unique world view and game-making philosophy, as well as a deep dive into the technology and economic design of his sci-fi simulation. He also…

1
Omer Goldberg - Chaos Labs and the Onchain Risk Management Landscape 49:44

4M ago49:44

49:44

In this episode, we chat with Omer Goldberg, founder of Chaos Labs, a company that builds economic security and risk management tooling for protocols. Omer has been in the trenches contributing to various DeFi protocols for the past few years, and shares some stories about that journey. We also chat about how Chaos has grown since inception, and wh…

1
How Blockchain Tech Advances Benefit Other Industries 1:16:54

4M ago1:16:54

1:16:54

with Dan Boneh @tim_roughgarden @smc90 In this special 50th episode of the web3 with a16z podcast, we discuss how work in the blockchains/ crypto space has led to advances in several important technologies — which can be (and are being) used by many other industries beyond crypto. Tim Roughgarden (a16z crypto Head of Research and professor at Colum…

1
Grand Challenges in Healthcare AI 37:40

5M ago37:40

37:40

Vijay Pande, founding general partner, and Julie Yoo, general partner at a16z Bio + Health, come together to discuss the grand challenges facing healthcare AI today. The talk through the implications of AI integration in healthcare workflows, AI as a potential catalyst for value-based care, and the opportunity for innovation in clinical trials. The…

1
Governing democracy, the internet, and boardrooms 1:35:38

5M ago1:35:38

1:35:38

with @NoahRFeldman, @ahall_research, @rhhackett Welcome to web3 with a16z. I'm Robert Hackett and today we have a special episode about governance in many forms — from nation states to corporate boards to internet services and beyond. Our special guests are Noah Feldman, constitutional law scholar at Harvard who also architected the Meta oversight …

1
Kubi Mensah - Gattaca and the MEV Supply Chain 1:22:55

5M ago1:22:55

1:22:55

In this episode, we chat with Kubi, co-founder of Gattaca, most well known for its Ethereum block builder Titan. We discuss Gattaca’s journey as a trading firm and how that led them to infrastructure development across the Ethereum MEV supply chain. We then explore their strategic approach to launching Titan Builder in an already competitive builde…

1
It’s Time to Build in Healthcare 41:04

5M ago41:04

41:04

Half of prescribed medications are never taken, and 88% of Americans are metabolically unhealthy. Despite spending 20% of our GDP on healthcare—twice that of any other developed nation—our outcomes still lag behind. In this episode, we explore why technologists must step into the healthcare ring. Solving medicine isn’t enough; we need to make healt…

1
Latin America: A Tech Powerhouse? 33:07

5M ago33:07

33:07

Latin America is emerging as a tech powerhouse, but it's not a one-size-fits-all market. In this episode, we explore why what works in Argentina won’t necessarily fly in Brazil or Mexico, and how companies are adapting to these unique regional dynamics. Join Dileep Thazhmon, Cofounder and CEO of Jeeves; Santiago Suarez, Cofounder and CEO of Addi; G…

1
The SSN Breach: What Now? 22:22

5M ago22:22

22:22

In this episode, we cover the recent data breach of nearly 3B records, including a significant number of social security numbers. Joining us to discuss are security experts Joel de la Garza and Naftali Harris. Incredibly enough, Naftali and his team were able to get their hands on the breached dataset and were able to validate the nature of the cla…

1
Governance Attack!? 1:02:17

5M ago1:02:17

1:02:17

with @ahall_research @eddylazzarin @0xShuel @smc90 In this episode, we cover both recent events + evergreen governance questions in political systems: Specifically, we breakdown the recent Compound “governance attack”... as well as the broader topic of DAO governance and voting in general. We also discuss how to avoid, prevent, and respond to such …

1
Building Innovation Hubs: The UK & Beyond 45:44

5M ago45:44

45:44

This episode from Web3 with a16z Crypto, is all about innovation on a global scale, exploring both ecosystem and individual talent levels. We examine what works and what doesn’t, how certain regions evolve into startup hubs and economic powerhouses, and what constitutes entrepreneurial talent. We also discuss the nature of ambition, the journey to …

1
The Olympics of Talent: France's Tech Boom 37:02

5M ago37:02

37:02

Once criticized for lacking ambition, French founders are now aiming to create the world’s largest companies. With a thriving ecosystem attracting talent from across Europe and the US, France is becoming a major player on the global stage. In this episode, we cover the unique advantages of building startups in France. Roxanne Varza, Director of Sta…

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A16z Crypto Podcasts

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