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Biology is breaking out of the lab and clinic—and into our daily lives. Our new ability to engineer biology is transforming not just science, research, and healthcare, but how we produce our food, the materials we use, how we manufacture, and much, much more. From the latest scientific advances to the biggest trends, this show explores all the ways biology is today where the computing revolution was 50 years ago: on the precipice of revolutionizing our world in ways we are only just beginnin ...
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Is it possible to eradicate poverty? What steps should be taken to ensure an environmentally sustainable future for our planet? Rio+20 is a United Nations conference that draws in participation from all over the world attracting members of governments, the private sector as well as NGO’s amongst the thousands of guests who attend. The primary reason being to develop strategies to reduce poverty, advance social equity and ensure environmental protection as we look to the future. In this colle ...
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Is it possible to eradicate poverty? What steps should be taken to ensure an environmentally sustainable future for our planet? Rio+20 is a United Nations conference that draws in participation from all over the world attracting members of governments, the private sector as well as NGO’s amongst the thousands of guests who attend. The primary reason being to develop strategies to reduce poverty, advance social equity and ensure environmental protection as we look to the future. In this colle ...
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The Lindisfarne Tapes
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The Lindisfarne Tapes

The Schumacher Center for a New Economics

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On a rocky outcropping off the northeastern coast of England, the monastery of Lindisfarne once stood as an outpost of religious, philosophic, and intellectual study against the “dark” times of early medieval Europe. Inspired by the foresight and dogged determination of these medieval monks, William Irwin Thompson founded the Lindisfarne Association in 1972 to gather together bold scientists, scholars, artists, and contemplatives to realize a new planetary culture in the face of the politica ...
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The Sustainability Agenda is a weekly podcast exploring today’s biggest sustainability questions. Leading sustainability thinkers offer their views on the biggest sustainability challenges, share the latest thinking, identify what’s working --and what needs to change -- and think about the future of sustainability.
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Regenerative by Design Podcast where we get to the root of health, climate, economics and food. Host, Joni Kindwall-Moore, is an RN, an Ethnobotanist and the founder of Snacktivist Foods. Join us on this journey as we explore the ideas, stories and personalities behind the regenerative food system movement including climate change, human health, economics and food as well as other deeply interconnected topics. In this podcast, we will be “going there” and leaning into topics that might make ...
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Delve into topical issues in zoology, conservation and the environment, from saving species and protecting the planet, to finding out about the animals living across the globe, including in London’s own river Thames. Learn more about the science behind the conservation work being done by ZSL and others, in this podcast from ZSL’s Institute of Zoology. Hosted previously by Dr Monni Böhm, and now by Ellie Darbey.
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The 1967 collapse of the Silver Bridge over the Ohio River was an engineering mystery and a human tragedy - 46 people died. Why did a suspension bridge built to last a century not make 40 years? Built in 1928, it was a slimmer version of similar bridges built in nearby Pittsburgh. The slimming down was deemed to be safe because of the use of a tougher steel and ‘silver coloured anticorrosion paint’. The tracks in this album look at the factors which led to the catastrophic failure of one of ...
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Border Criminologies brings together academics, practitioners and those who have experienced border control from around the world. Showcasing original research from a range of perspectives, we hope to better understand the effect of border control and to explore alternatives. Through an emphasis on visual resources and first hand accounts we hope to flesh out our understanding of the lived experience of law and policy and to develop the emerging field of inquiry into border control within cr ...
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Today's episode features Aviv Regev, PhD, the Head and Executive VP of Genentech Research and Early Development, and founding co-chair of the Human Cell Atlas. She is joined by Vijay Pande of Bio + Health. Together, Aviv and Vijay talk about how Aviv's love of both abstractions and details led her to biology, how CRISPR really set the field into mo…
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In this fascinating, hard hitting interview, Jason Moore talks about the intertwining relations between environmental degradation, capitalism, imperialism, and climate change-stressing the need to recognize the role of imperialis--and counter-insurgency across the past century to advance climate justice. He argues it is naïve to believe that eco-so…
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Andrew Ng, PhD, a distinguished authority in the field of AI, is known for founding DeepLearning.AI and multiple other ventures. He also co-founded and led Google Brain and serves as an Adjunct Professor in Stanford University's Computer Science Department. In this episode, he is joined by Vijay Pande, founding partner of a16z Bio + Health. Andrew …
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Carl June, MD, an immunologist and oncologist at the University of Pennsylvania, joins Jorge Conde, general partner at a16z Bio + Health. Together, Carl and Jorge talked about Carl's pioneering work in CAR T therapy — including the terrifying moment where he thought he had accelerated one of his patient's deaths, how he started working in human imm…
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Dan Nomura is a distinguished professor at UC Berkeley and an Investigator at the Innovative Genomics Institute, specializing in Chemical Biology and Molecular Therapeutics. He serves as the Director of the Novartis-Berkeley Translational Chemical Biology Institute and founded Frontier Medicines and Vicinitas Therapeutics. He’s also a16z Bio+Health…
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In this exclusive conversation from the Bio + Health BUILD summit, founding partner Ben Horowitz sits down with general partner Jorge Conde. They discuss everything from the inspiration behind Ben’s book The Hard Thing About Hard Things, how the open Internet was secured, the difference between wartime and peacetime CEOs, scaling culture, and under…
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Fascinating discussion with Professor Angel Hsu on the significance and challenges surrounding the Net Zero emissions goals. While companies often tout their commitment to Net Zero, a recent report suggests that many are not taking credible steps towards this target. Angel argues that the Net Zero space is filled with confusion and misinformation, …
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Together, Lloyd and Vijay chatted about how AI could change the practice of medicine, and what the implications are for medical students now and in the future. join Lloyd and Vijay as they discuss AI and medical education—from how students learn to how doctors become licensed.By Lloyd B. Minor, Kris Tatiossian, Olivia Webb, Vijay Pande
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In this wide-ranging interview, first published in 2021, Jeremy Lent discusses his fascinating new book Web of Meaning which combines findings in cognitive science, systems theory and traditional Chinese and Buddhist thought, to develop a framework that integrates both science and meaning in a coherent whole. Jeremy discusses what he sees as an ess…
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Together, Margaret and Julie chatted about Margaret’s background — and how she taught herself to program — her time at Devoted, and the advice she gives to healthtech CEOs. Join Margaret and Julie as they discuss building a developer-friendly environment in healthcare, introducing engineers to the complexity of the industry, and how AI might affect…
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Together, Vijay and Zak talked about having been through AI winters and hype cycles before, and why they think this time could be different. They also talked about how AI could revolutionize the healthcare model — what Zak calls the “flipped clinic.” Join Zak and Vijay as they talk about how AI could flip the clinic, how foundation models could qui…
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Dan Rosenthal, a provider network expert and the newest advisory partner for a16z Bio + Health, joins Julie Yoo, general partner. Together, they talk about the 101 and 201 of provider networks, tactical advice for digital health builders, and how AI could theoretically change the way networks are constructed.…
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The holy grail of company building is finding product-market fit. But what most people don’t tell you is that once you’ve found it, product-market fit brings its own set of challenges, particularly when it comes to scaling rapidly and hiring the right executives at the right time. Drawing from their extensive experiences, a16z cofounder Ben Horowit…
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In this in-depth, and spirited interview, we discuss the pros and cons of a market based approach to our environmental problems-and climate change in particular. Paula DiPerna discusses her new book, Pricing the Priceless: The Financial Transformation to Value the Planet, Solve the Climate Crisis, and Protect Our Most Precious Assets, arguing for a…
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When Greg started out in science, he heard other researchers referring to certain targets as “undruggable.” In response, he’s devoted his life to drugging the undruggable, cofounding the field of chemical biology along the way. After a robust career founding multiple biotechs and serving as the cofounder, chairman, and CEO of FogPharma, he is the n…
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After his own health scare, Jeffrey got obsessed with how MRIs work—and decided that they were too unscientific to really track human health over time. In response, he built a new kind of imaging, creating a “digital twin” that can be tracked over time. And if health can be tracked over time, in theory it could eventually become as forecastable as …
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AI has the potential to save the world — that’s the thesis of Marc’s most recent article, linked below. This episode was recorded right after Marc published his article, live from a16z Bio + Health’s first summit. Join Marc and Vijay as they talk about how AI can save the world, and where it can go wrong. Additional reading: Why AI Will Save the Wo…
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In this interview, British novelist, journalist and screenwriter Ned Beauman discusses his latest novel Venomous Lumpsucker-a brilliant, darkly satirical and terrifying novel about endlings (the last of a species), the manipulation of extinction credit markets... the elusive Hermit Kingdom: described by The Times Literary Supplement as “a tale of c…
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AI is not just a sci-fi concept anymore; it's being woven into the fabric of healthcare, revolutionizing everything from research to patient care. It has the potential to create more streamlined and efficient processes. The challenge now is how we adapt and regulate this ever-evolving technology, while ensuring safety and trust. Amy Abernethy, form…
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In this episode, taken from a live a16z event, Bio + Health general partner Vineeta Agarwala moderates a panel of UCSF faculty founders, including Michelle Arkin, Jimmie Ye, and Natalia Jura (full bios below). Together, they discuss fundraising, the decision to stay in or leave academia after founding a company, and their tips for managing the IP p…
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Today’s episode is with Mark Cuban, founder of multiple businesses, owner of the Dallas Mavericks, one of the sharks on Shark Tank, and cofounder of the Mark Cuban Cost Plus Drug Company. He is joined by Vijay Pande, founding partner of a16z Bio + Health. Together, they talk market forces in healthcare, the importance of trust to patients, and Mark…
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Today’s episode is a cross-post with the a16z podcast. It features founders—Chris Severn, Florian Otto, Andrew Adams, Jade Chan, Jimmy Chen, and Fay Rotenberg—chatting with a16z podcast host Steph Smith, about how they're trying to reinvent the healthcare system, using fintech. Additional reading: https://a16z.com/healthcare-meets-fintech/ https://…
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In this revealing interview, Mike Davis CEO of pioneering campaigning NGO Global Witness provides an in-depth look at the work of the organization which is committed to uncovering and addressing human rights and environmental violations across the globe. Mike highlights the organization's intricate investigative strategies used to reveal the interp…
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Today’s episode is with Greg Meyers, EVP and Chief Digital and Technology Officer at Bristol Myers Squibb (or BMS). He is joined by a16z Bio + Health general partner Jorge Conde. Together, they talk about how AI could transform drug discovery and development at a large biopharma company—and how a company might have to adapt to harness AI; modalitie…
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Healthcare payments are difficult, confusing, and opaque. But Julie and David discuss the ways that technology could change that for the better, and where they see the greatest opportunity for founders to solve big challenges. Additional reading: https://a16z.com/healthcare-meets-fintech/ https://a16z.com/2023/02/07/healthtech-x-fintechs-biggest-pr…
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In this episode, Dr Samantha Montana, an expert in disaster policy, discusses the U.S.'s approach to emergency management, specifically in the context of climate change. She highlights the complexity of disaster policy, which often necessitates a balance between immediate and long-term action. She explains that the U.S. has traditionally taken a re…
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In this episode, a16z Bio + Health investment partner Becky Pferdehirt chats with Robbie Majzner, an Assistant Professor of Pediatrics in the Division of Hematology and Oncology at Stanford, and co-founder of Link Cell Therapies. Together, they discuss Robbie's recent paper published in Nature. The paper outlines a new approach to develop logic gat…
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Today’s episode is with Magi Richani, founder and CEO of Nobell Foods. She is joined by a16z Bio + Health general partner Vijay Pande. Together, they talk about the details of engineering plants to create the future of food, why Nobell started with soybeans to produce their cheese, and her dream of finding a cheese pizza—with Nobell cheese—at any p…
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In this deep dive on resilience, Professor Daniel Aldrich gives a fascinating overview of different ways of thinking about resilience—focussing in particular on the kind of resilience that allows communities to recover from disasters in a way that brings together resources — and allows the communities to rebuild themselves so they’re not as vulnera…
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This is a crossover episode with The Bioverge Podcast, hosted by Neil Littman. Neil is joined by Vineeta Agarwala, general partner at a16z Bio + Health. Together, they chat about Vineeta's dual role as a clinician and investor, the adoption curve of digital therapeutics, how Vineeta thinks about platforms and a modular, engineering-driven approach …
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Today’s episode is with a16z’s American Dynamism team: Katherine Boyle and David Ulevitch. Katherine is a general partner focused on national security, aerospace and defense, public safety, housing, education, and industrials. David is a general partner focused on companies promoting American dynamism, as well as enterprise and SaaS companies. They…
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In-depth, frank, and fascinating exploration of contemporary literature's response to current environmental crises, with Scottish writer Martin MacInnes, author of the recently acclaimed novel, In Ascension. Martin believes literature is profoundly implicated in the crises, and that it has a responsibility to challenge certain assumptions regarding…
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Today’s episode is with Sean Duffy, cofounder and CEO of Omada Health. He is joined by a16z Bio + Health general partner Julie Yoo and investment partner Jay Rughani. Together, they talk about Sean’s three rules of partnerships, how Omada plans for large-scale implementation, and how Sean thinks about structuring the economic model of the partnersh…
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This week, we’re releasing two episodes about all things channel partnerships. Today’s episode is with Florian Otto, cofounder and CEO of Cedar. He is joined by a16z Bio + Health general partner Julie Yoo. In today’s episode, Florian and Julie talk about how Cedar began engaging with channel partners, what happens when things go wrong, and how the …
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In this episode, Daphne Koller, founder and CEO of insitro—as well as the co-founder of Coursera, a MacArthur Award winner, and a former professor in the department of computer science at Stanford University—chats with a16z Bio + Health founding partner Vijay Pande. Together, they talk about Daphne’s career journey, how Daphne thinks about the last…
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Today marks the reboot of our journal club series, so you can look forward to seeing these episodes as part of our regular feed. This episode is a scientific deep dive on recent research published by Ben Cravatt, Professor in the Department of Chemistry at the Scripps Research Institute and co-founder of a diverse suite of chemoproteomic companies …
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In this episode, a16z Bio + Health general partner Julie Yoo chats with Bassett Healthcare Network president and CEO Tommy Ibrahim. Together, they talk about Tommy's journey from practicing physician to health system leader, the challenges facing rural healthcare today, and how Tommy thinks about partnering and integrating with digital health entre…
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The world is facing a crisis of species extinction, however targeted efforts in conservation biology can provide a glimmer of hope. A new study led by ZSL, published recently in Science, is the first to assess animals and plants categorised as ‘Extinct in the Wild’ by the IUCN’s Red List of Threatened Species – until now, a surprisingly overlooked …
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In this eye-opening interview, Professor Neta Crawford discusses the research in her new book The Pentagon, Climate Change, and War focussing on the huge carbon footprint of the Pentagon -- the world’s largest single greenhouse gas emitter. She tracks the interconnect long-term cycles of economic growth, and fossil fuel use-and growth of the US mil…
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In this episode from the archives, originally published in February 2021, Jennifer Doudna, who won the 2020 Nobel Prize for the co-discovery of CRISPR-Cas9 with Emmanuelle Charpentier, chats with Vijay Pande, general partner at a16z Bio + Health. Together, they discuss the future of biology, whether discovery itself can be engineered and industrial…
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In this episode, Jorge Conde, general partner at a16z Bio + Health, talks with Josh Mandel-Brehm, founding CEO of CAMP4. Together, they talk about how CAMP4 focuses on regulatory RNA (and what that means), how Josh thinks about platform companies, and what he’s learned as the founding CEO of the company.…
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In today's episode, Sam Corcos, CEO and cofounder of Levels Health, chats with Vijay Pande, general partner at a16z Bio + Health, about how Sam cofounded Levels, how to decide who becomes CEO if you have multiple cofounders, Levels’ approach to company culture and meetings, and how Sam thinks about the complicated world of healthcare regulations. A…
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In this episode, Kurt Adams, CEO of Optum Financial, chats with Daisy Wolf, investment partner for a16z Bio + Health, and Marc Andrusko, investment partner for a16z focused on fintech, about Optum Financial, how consumers might interact with fintech while seeking care or participating in healthy behaviors, and what a fintech-integrated version of t…
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In this fascinating interview, first aired April 13th 2021, Dr. Jeffrey Kiehl brings to bear two very different ways of thinking about climate change: the scientific and the psychological—and his journey as an experienced climate scientist to bring these different perspectives together. Jeffrey explains the essential features of a depth psychologic…
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In this episode, Joe Lonsdale, founder and managing partner at 8VC, joins Vijay Pande, founding partner of a16z Bio + Health, and Olivia Webb, editorial lead. Together, we talk about what factors lead to innovation vs stagnation, monopoly power in healthcare, and policy ideas to incentivize change, growth, and dynamism.…
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In this episode, Julie Yoo, general partner, and Jay Rughani, investment partner at a16z Bio + Health, talk to Kate Ryder, founder and CEO of Maven; Amanda Rees, cofounder and CEO of Bold Health; and Bill Porter, VP and GM, International, of Butterfly Network, about their B2C2B go-to-market motion. This episode was originally recorded in late 2021,…
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In this episode, Kevin Parker, cofounder and CEO of Cartography Biosciences, joins Jorge Conde, general partner at a16z Bio + Health, and Olivia Webb, editorial lead, to discuss immuno-oncology, current challenges in drug targeting, and the mechanisms Cartography and others are using to advance the field of immunotherapeutics. This episode dives de…
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In this fascinating interview, first aired in June 2020, renowned climate scientist Will Steffen discusses Earth System science, and his research on so-called “tipping cascades,” when one tipping point kicks off a series of others, posing a growing threat of abrupt and irreversible climate changes. Will draws parallels between -19 and climate chang…
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Peter Sutoris believes that the Anthropocene challenges the very definition of education and, indeed, its key goals. He argues that educators must look outside conventional models and ways of education for inspiration --if education is to live up to its responsibilities at this critical time. In this revealing interview, Peter shares the results of…
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In this episode, Kristen Fortney, cofounder and CEO of BioAge, joins Vijay Pande, founding partner of a16z Bio + Health, and Olivia Webb, editorial lead, to discuss the biology of aging, how she started a company, and some fun things — like how long a hypothetical venture capitalist can expect to live. Additional reading: Greg Egan, whose writing i…
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