Best Tony Mayo Podcasts (2024)

1
EP 149: Sequencing 33 million samples to support the UK’s COVID-19 response with Tony Cox, CEO of UK Biocentre 34:16

1h ago34:16

34:16

0:00 Intro to The Genetics Podcast 01:00 Welcome to Tony 02:00 What Tony was expecting going into the role of CEO at UK Biocentre, and how the COVID-19 pandemic changed his plans 03:38 Receiving a phone call from the UK government in March 2020 asking the UK Biocentre to stop all of its projects and focus on sequencing COVID-19 samples 05:12 The UK…

1
Fun at the DNC: Kamala’s Obvious Lies and Hamas Take Center Stage / Democrats Finally Embrace Walls, But Only for Themselves / Chapo’s Son Accused of Capturing the World’s Biggest Drug Dealer — And Gets ... 52:28

5d ago52:28

52:28

In this episode, Jeff delves into the recent Democratic National Convention in Chicago, where Kamala Harris swore she is the only one who can fix America’s current problems while conveniently ignoring her role in creating the mess over the past four years. The real show, though, was outside, where pro-Palestinian rioters attempted to turn the conve…

1
EP 148: Advancing veteran health through the Million Veteran Program with Dr. Mike Gaziano, professor of medicine at Harvard Medical School 35:13

22h ago35:13

35:13

0:00 Intro 2:00 Mike’s career prior to the Million Veteran Program (MVP), how Mike got to work on MVP, and important milestones in the project's evolution 8:30 Future goals for the Million Veteran Program in expanding and diversifying the research cohort 11:00 The roles of various omics in advancing the project's development 14:30 The most meaningf…

1
EP 147: From research to delivering precision medicine in the clinic with Scott Weiss, Professor of Medicine at Harvard University 37:19

27m ago37:19

37:19

0:00 Intro to The Genetics Podcast 01:00 Welcome to Scott 01:55 Scott’s career highlights to date, ranging from epidemiology to the genetics of asthma and chronic obstructive pulmonary disease (COPD) 04:56 How and why Scott decided to transition into genetics 06:30 The advances in our understanding of the genetics of asthma and COPD over the past 2…

1
EP 146: The biology of aging with Austin Argentieri, Research Fellow at Harvard Medical School, Affiliate Member of the Broad Institute, and Research Fellow at Massachusetts General Hospital 43:05

5d ago43:05

43:05

0:00 Intro to The Genetics Podcast 01:00 Welcome to Austin 01:42 What is aging and how should we think about it? 03:50 Discussion of Austin’s recent breakthrough paper on aging, including the questions he set out to answer, and the outcomes of the research 06:32 How Austin’s work focuses on using large-scale population proteomics data to create acc…

1
“El Mayo” Arrested: My Week In Chicago / Kamala Harris Was Anointed, Not Elected as the Nominee / How Can Blacks Support Harris After What She Did to Them? / It’s Time to Remove the Cancer in Iran 1:02:10

26d ago1:02:10

1:02:10

In this podcast, Jeff describes his hectic week which started with the startling news of the arrest of a 50 year fugitive, “El Mayo” Zambada and the murky circumstances around his capture. Jeff ended up in court in Chicago to represent Joaquin Guzman Lopez, the son of “El Chapo” and the second person on the plane with El Mayo when they touched down…

1
EP 145: Navigating rare disease drug development regulations with Daniel O’Connor 39:12

1M ago39:12

39:12

0:00 Intro to The Genetics Podcast 01:00 Welcome to Daniel 02:04 Defining rare disease in the age of personalized medicine 04:57 Key touchpoints with the Medicines and Healthcare products Regulatory Agency (MHRA) when developing a new medicine 09:27 Improvements over the course of Daniel’s career when it comes to incentivizing and making the path t…

1
EP 144: Research Roundup with Dr. Veera: breakthroughs in developmental disorders, Parkinson's, SLE, and Alzheimer's 56:48

26d ago56:48

56:48

0:00 Introduction 1:40 A recurrent de novo mutation in a noncoding region of a small nucleolar RNA gene that has been identified as one of the most common causes of neurodevelopmental disorders This pathogenic variant escaped notice for years because it was not located in a protein coding region of the genome It now shows potential as a target for …

1
Joe Biden Gets Pushed Out of the Presidential Race: A Humiliating End Following a Coverup of Epic Proportions / Does Anyone Actually Believe Trump’s Attempted Assassin Acted Alone? 43:09

1M ago43:09

43:09

In this episode of Beyond the Legal Limit, Jeff dissects the monumental news of Joe Biden dropping out of the presidential race. It's not because he recognized his incompetence, but because his disastrous debate performance left him without support. Jeff describes Biden's fall as a humiliation he richly deserved, detailing how his party, advisors, …

1
EP 143: Harnessing human data in drug development with Jakob Steinfeldt, Co-Founder and Chief Scientific Officer at Pheiron 36:17

1M ago36:17

36:17

0:00 Intro to The Genetics Podcast 01:00 Welcome to Jakob and background on Pheiron 02:14 What made Jakob decide to start Pheiron, what the company does, and how his scientific background inspired him to found a start-up 5:24 Jakob’s excitement and inspiration around the power and potential of machine learning 07:07 Cardiology and heart failure as …

1
EP 142: From genome to bedside: How genetics is transforming modern medical practice with Dr. Andrea Gropman 42:45

2M ago42:45

42:45

0:00 Introduction 1:40 Andrea’s background and how she got into the field of genetics, neuroimaging, and metabolic disorders 4:00 Insights into Andrea’s clinical practice, including the diverse families and patients she serves and her approach to clinical decision-making 6:30 How genetics and genomics have changed the diagnostic journey in the last…

1
Sick of the News: A Return to Legal Battles / The Trump-Biden Debate Debacle 45:33

2M ago45:33

45:33

In this episode of Beyond the Legal Limit, Jeffrey Lichtman takes a trip down memory lane, recounting his teenage years during the Iran hostage crisis and his bold fashion choices at Spencer Gifts. Reflecting on his long-standing frustration with the stagnant state of world affairs, Jeff vents about the repetitive and disheartening news cycle that …

1
EP 141: Bringing genomics to the clinic with Lori Orlando, Associate Prof at Duke University 43:24

2M ago43:24

43:24

0:00 Intro to The Genetics Podcast 01:00 Welcome to Lori Orlando 03:00 Lori’s career: From mathematical modelling to genetics and family history 05:11 The study that revealed 20% of the general population is at a higher risk of disease than average and needs preventative care 07:36 The first five diseases that Lori started analysing through informa…

1
EP 140: The future of Electronic Health Records and data analysis with Ben Goldacre 52:51

2M ago52:51

52:51

0:00 Intro to The Genetics Podcast 1:00 Welcome to Ben Goldacre 02:22 Ben’s open data projects at the Bennett Institute and the challenges they aim to tackle 04:03 Using Electronic Health Records (EHR) to help the National Health Service improve care 06:18 The importance of software development within healthcare data and how to manage salary scales…

1
The Unchecked Spread of Hate in America 48:09

2M ago48:09

48:09

In today's episode, Jeff opens up about his deepening sense of hopelessness regarding the current state of America and its far-reaching implications for the world. He tackles the alarming rise of radical Islam combined with extreme liberalism and the surprising alliances formed with fringe far-right groups, all united by a shared hatred. Jeff doesn…

1
EP 139: Rare disease breakthroughs using tRNA with Michelle Werner, CEO of Alltrna and CEO-Partner of Flagship Pioneering 44:42

2M ago44:42

44:42

0:00 Intro to The Genetics Podcast. 01:00 Welcome to Michelle. 02:00 Sstop codon diseases and how are they characterised 03:45 Diseases caused by premature stop codons in haploinsufficient genes. 04:35 The role of transfer RNA technology in finding solutions for premature stop codon diseases. 06:16 How Alltrna is engineering tRNAs which can bind to…

1
EP 138: Personalised medicine using microbiome models with Dr. Almut Heinken 40:22

3M ago40:22

40:22

0:00 Introduction 1:45 Almut’s research experience, including two recent publications on genome-scale metabolic reconstruction human microorganisms Genome-scale metabolic reconstruction of 7,302 human microorganisms for personalized medicine APOLLO: A genome-scale metabolic reconstruction resource of 247,092 diverse human microbes spanning multiple…

1
The Trump Guilty Verdict: His Lawyers Need to Stop the Excuses / Why is America Filled With Muslim Terror Supporters? Why Doesn’t Anyone Seem to Care? 46:40

3M ago46:40

46:40

In this podcast, Jeff takes to task Donald Trump’s defense attorneys who expressed their belief they never had a chance at trial. Does any high profile defendant have a decent chance in a criminal trial in NYC? Of course not — but that doesn’t mean the lawyers should give a lackluster, whiny effort. Clear, avoidable mistakes were made and yet again…

1
EP 137: Mavis Machirori on promoting equity, diversity, and social justice in genomics research 41:40

3M ago41:40

41:40

0:00 Intro 1:30 Mavis’ career arc, from starting as a midwife to researching medical innovation and technology with an emphasis on advocacy and equity 7:00 Systemic issues that are easily overlooked in medical research and advancements Webinar: Participant Diversity: Increasing the Impact of Biomedical Research Webinar 10:00 Addressing Eurocentrici…

1
Eisner FYC #1: Tony Fleecs For Best Tony in Comics 32:59

3M ago32:59

32:59

The Latinx Press Podcast is back! I'm giving my friends who are up for Eisners their chance to sway your vote! Professionals, if you haven't already, don't forget to vote! You can vote! Click here to verify your eligibility and make your voice heard! Tony Fleecs returns to the podcast to make his case for your vote! His works Local Man and Stray Do…

1
EP 136: Developments in ring chromosome 20 research and advocacy with Allison Watson 40:57

3M ago40:57

40:57

0:00 Introduction 2:00 Allison’s personal journey to researching epilepsy and ring chromosome 20 syndrome 4:00 Biggest challenges families face with ring chromosome 20 syndrome 11:00 Incidence and prevalence of r(20) syndrome, and how we can improve data reliability 21:00 Applying next generation sequencing to r(20) syndrome gene research 29:00 Eng…

1
EP 135: Integration of newborn sequencing programs into healthcare systems with Dr. Ingrid Holm 41:16

3M ago41:16

41:16

0:00 Introduction 1:30 Ingrid’s initial interests in genetics, paediatrics, and newborn screening 2:45 How the original BabySeq project, a pioneering newborn sequencing program got started, how it’s going, and the launch of BabySeq2 8:45 Lessons from BabySeq1 and goals for BabySeq2 10:30 Potential societal and long-term considerations for those inv…

1
EP 134: Prenatal genetic testing and the future of AI in genetic counselling with Kira Dineen, host of DNA Today 40:44

3M ago40:44

40:44

0:00 Introduction 1:00 The backstory of how Kira first started DNA Today in 2012, when she was still in high school! 3:30 Some of Kira’s favourite topics she has discussed on DNA Today, including the legacy of Henrietta Lacks, and the story of a Glee actress with down syndrome 10:00 Kira’s best practices for podcasting, from over 10 years of experi…

1
EP 133: Insights into pharmacogenomics and increasing diversity in genomics research with Dr. Emma Magavern 39:17

3M ago39:17

39:17

0:00 Introduction 2:00 The value of an English Literature degree in designing and analysing research studies in medicine 3:45 Emma’s entrance to pharmacogenomics and her transition from practising physician to genetics research 6:00 How the East London Genes and Health program is increasing representation of diverse populations, namely South Asians…

1
Jihad on Campus: How to Beat it Back (Including My Lawsuit Against Columbia University) 54:25

4M ago54:25

54:25

In this explosive episode of Beyond the Legal Limit, Jeffrey Lichtman delves into the disturbing rise of extremist activities on college campuses, focusing on a recent incident at Columbia University where Jewish students were targeted by pro-Hamas radicals. Imagine sending your child to a prestigious university, only to find they're subjected to h…

1
EP 132: From mammoths to genome editing, trailblazing genetics with Dr. George Church 47:41

4M ago47:41

47:41

0:00 Introduction 1:00 George’s upcoming big projects, including developing full recycling, renewing energy, creating bioweather maps, and harnessing citizen science 6:45 Progress in engineering viral resistance in humans, including thoughts from pre- and post- pandemic 11:00 A swapped genetic code that prevents viral infections and gene transfer b…

1
EP 131: The potential of somatic genomics in drug discovery and development with Jake Rubens 44:57

4M ago44:57

44:57

0:00 Intro 0:40 Jake’s experiences as a serial entrepreneur starting five companies with a basis in genomic science 5:30 Opportunities for research and drug development in the realm of somatic science 9:20 Somatic evolution and how it provides valuable insights into disease mechanisms 12:30 Advantages and disadvantages of studying germline genome-w…

1
Iran Attacks Israel; Joe Biden Deters No One As He Still Appeases Radical Islam / The Who vs. Led Zeppelin: Why The Who Always Comes in Second 1:16:42

5M ago1:16:42

1:16:42

In this podcast, Jeff discusses the Iranian missile attack on Israel which could have led to thousands of deaths if not for the skill of the Israelis and the incompetence of Iran. Regardless, a new status quo must be set: any Iranian terror proxy attack on Israel needs to be met with an attack on Iranian soil. Furthermore, the celebrations by the “…

1
EP 130: Quarterly insights into noncoding variants and GWAS with Dr. Veera Rajagopal 51:56

5M ago51:56

51:56

Show Notes: 0:00 Introduction 1:20 How polydactyl mutations can inform research on non-coding variant mechanisms The importance of low-affinity binding between transcription factors and targets How these lessons can help us improve our understanding of drug and target discovery See Veera’s January round-up for more information: https://www.gwasstor…

1
EP 129: Patient advocacy for genetic ALS and FTD with Jean Swidler, Executive Director of End the Legacy 38:44

4M ago38:44

38:44

0:00 Introduction 0:45 Jean’s personal experiences with family members with genetic ALS 10:00 Jean’s thoughts on the barriers and facilitators to providing treatment for those with genetic ALS 13:20 Insights into C9orf72, a common genetic determinant of ALS, and how it can also be associated with FTD 16:10 Jean’s experiences as an active advocate f…

1
Life When I Was a Kid / The P. Diddy Case / Vanderbilt Handles Terrorist Students, Northwestern Not So Much / Why do White Supremacists Love Hamas? / Greatest Music Album Ever 53:17

5M ago53:17

53:17

In this April Fool’s Day podcast, Jeff reminisces about simpler times and lemonade stands, a time before the internet and cell phones — and how kids used to learn about new music. Jeff opines on the over the top searches of Sean Combs’ two homes as he reveals he’s been hired to represent P. Diddy’s son. The government rarely fights fair when they h…

1
EP 128: Parkinson’s disease and precision medicine with Drs. James Beck and Ignacio Mata 50:18

5M ago50:18

50:18

0:00 Introduction 1:05 Insights into the PD GENEration’s (a programme from the Parkinson's Foundation) milestones and progress points for the upcoming year 3:30 The shifting attitudes and perspectives of neurologists and healthcare workers at the PD GENEration 5:50 Insights into Nacho’s work with the genetics of Parkinson’s disease 10:20 Barriers a…

1
Michael Cohen Found a Lawyer Dumber Than Him / My Week: From Chapitos in Chicago to an Easy to Anger Woman Lawyer / The Clash / Democrats Abandon Israel 1:09:34

5M ago1:09:34

1:09:34

Jeff dives into the almost comedic legal saga of Michael Cohen, Trump’s former fixer, and his quest to end his federal supervised release early. Despite the steep odds, Cohen found a lawyer dumber than him and hilarity ensues. Jeff’s week also ran the gamut from representing Chapo’s son in Chicago on Monday to being on the business end of an emotio…

1
EP 127: Insights into precision medicine, fatty liver disease, and minimally invasive diagnostic tools with Dr. Mazen Noureddin 39:10

5M ago39:10

39:10

0:00 Intro 0:25 Mazen’s lifelong commitment to furthering the field of precision medicine in liver disease research, fueled by a personal connection of his grandmother developing MASH cirrhosis 2:30 Breakthroughs in the field of metabolic dysfunction-associated steatotic liver disease (MASLD) since the beginning of Mazen’s career 5:30 The potential…

1
EP 126: Patient-led research for ultra-rare disease drug development with Julia Taravella, Executive Director of Rare Trait Hope Fund 39:41

5M ago39:41

39:41

0:00 Introduction 0:25 Julia’s personal experience with ultra-rare diseases within her family 10:25 The importance of increasing accessibility to genetic testing across populations to learn more about ultra-rare diseases 14:00 The origin story of Rare Trait Hope Fund 23:50 Current research and next steps in developing potential gene therapies for a…

1
Musical Evolution Leads to a Disgusting Story or Two / Devo & The Rolling Stones / Joe Biden is Openly Helping Hamas Just To Win the Terrorist Vote in Michigan 58:15

6M ago58:15

58:15

Jeff explains how he discovered the band Devo — and led him to rediscover the Rolling Stones. All of this sets the stage for some disgusting stories about peanut brittle and school stairwells. In other news, Joe Biden is terrified of losing the Muslim terror vote in Michigan. So what if these voters openly support Hamas and claim the October 7 mass…

1
EP 125: The future of UK Clinical Trial Policy: Innovation, integration, and game-changing legislation with Lord James O’Shaughnessy 45:23

5M ago45:23

45:23

0:00 Introduction 1:25 How Lord O’Shaughnessy became involved in scientific policy making and his path to writing the UK Commercial Clinical Trials Review. 04:05 How Lord O’Shaughnessy pivoted from education to a focus on life sciences 06:38 The biggest challenges Lord O’Shaughnessy faced during his time as Parliamentary Under Secretary for Health …

1
EP 124: How ReCode Therapeutics is pioneering tissue specific delivery of gene therapies for Primary Ciliary Dyskinesia with John Matthews 42:00

6M ago42:00

42:00

0:00 Introduction 01:10 How growing up in Malawi planted the seeds for John’s career in medicine and transition to therapeutic development 04:35 Why John focuses on rare diseases and conditions such as asthma 06:01 What has changed over the last decade in terms of treating and understanding asthma and the progress that genetics has enabled 07:31 Wh…

1
I Hate Trump but Trump Got Screwed / Joe Biden is Appeasing Hamas Supporters For Votes — Can This Guy Ruin America Even More? / Update on Assisting Suicide Case / Two Musical Interludes: Velvet Underground ... 1:07:27

6M ago1:07:27

1:07:27

In this podcast, Jeff admits that although he is not a Trump fan, it’s simply impossible to ignore the fact that the criminal and civil trials brought against him were done so to prevent his election. None of these cases were serious enough that they needed to be brought. But they were and it wouldn’t be so painful if his opponent was even remotely…

1
EP 123: The ethics of newborn genome screening: Actionable insights and beyond with Holly Peay, Senior Research Scientist at the Research Triangle Institute 45:34

6M ago45:34

45:34

0:00 Introduction 0:50 Holly’s background and career so far 03:30 Complex decision-making and multiple risk factors: Family history, genetics, phenotypes and beyond 07:05 Changes within the last decade to help people make complex, sometimes subjective, healthcare decisions 09:20 Impact on people: The RTI’s mission and the Early Check Study 13:45 Ne…

1
EP 122: Building genome-scale engineered cells for biotechnology with Leslie Mitchell, Co-founder and CEO of Neochromosome 35:55

6M ago35:55

35:55

Summary: 0:00 Introduction 01:01 How Leslie got into the field of synthetic biology and engineering, and her career journey so far 02:45 What Leslie accomplished during her postdoc and recent transformations in the field of genomics 05:57 The impacts of non-coding regions of the genome and the outcome of deletions 08:20 How long it takes to make ch…

1
EP 121: Breakthroughs and insights in ALS research with Dr. Michael Benatar 44:10

7M ago44:10

44:10

Summary: 0:00 Introduction 0:50 Reflections from the 34th International Symposium on ALS/MND in Basel 1:50 Michael’s professional journey, initial challenges he encountered, and how the field of neurology has evolved over the years 3:10 An introduction to the ALS landscape, including its presentation, the genes involved, and potential treatment opt…

1
Judge Kaplan Hates Dumb, Unprepared Lawyers It Seems / Assisted Suicide Client Has High Stakes Bail Hearing / Dems’ Dual Election Strategies: Open Borders and Appeasing Muslim Terror Supporters 1:09:52

7M ago1:09:52

1:09:52

In this new podcast, Jeff describes two court appearances from this past week, one before Trump’s judge from his defamation case and the other the detention hearing for his assisted suicide-charged client; a loss would guarantee his elderly client dying in jail before he even gets to trial. Otherwise, Jeff points out the Democrats’ dual election st…

1
EP 120: Exploring the frontiers of gene therapy and AAVs with Dr. Nicole Paulk, CEO and Founder of Siren Biotechnology 43:47

7M ago43:47

43:47

0:00 Introduction to Dr. Nicole Paulk, a pioneer in AAV research and the founder of Siren Biotechnology 0:50 The moments that shaped Nicole’s career path and her passion for gene therapy and AAV research 9:20 Nicole’s academic research career and her transition from academia to the biotech industry 23:00 The story behind the founding of Siren Biote…

1
Another Trump Trial, Another Comically Bad Trump Lawyer, Another Trump Loss / Musical Interlude / Two New Cases: Assisted Suicide & Terrorists Made to Smell Bad 58:22

7M ago58:22

58:22

In this new podcast, Jeff patiently breaks down the disastrous handling of Trump’s latest trial: it couldn’t be more obvious that his lawyer had never tried a federal case before. What does that tell us about Trump’s judgment when he hires the dumbest lawyer in America? A music recommendation. Just listen to it, you’ll thank Jeff later. And some br…

1
EP 119: Revolutionising drug discovery: how the Pharma Proteomics Project is combining genetic and proteomic data with Chris Whelan 38:25

7M ago38:25

38:25

0:00 Introduction 01:00 Chris’ background and career to date 02:10 What is the Enigma Project? 04:48 How is genetics being applied to drug discovery today and how does proteomics fit in? 09:23 When the UKBiobank Pharma Proteomics Project began and how long it took to set up 10:57 54k UK Biobank participants tested - discussion of findings 14:33 The…

1
EP 118: The role of genetics in drug discovery and development with Dr. Matt Nelson 42:56

7M ago42:56

42:56

Summary: 0:00 Introduction 5:45 Lessons learned from 15 years at GSK: How has genetics and drug discovery evolved over time? 8:10 Matt’s seminal 2015 paper: Quantifying the impact of human genetic evidence on the probability of success in drug development 11:40 Which types of genetic evidence are the best drivers of success in clinical trials? 13:3…

1
Far Left Democrats Openly Support Iran Against America — Or Why I’ve Had Enough With Liberals / Saying That Claudine Gay Was a Victim of Racism Is Like Saying Hamas Are Freedom Fighters 52:57

8M ago52:57

52:57

In this new episode, Jeff explains how liberals have gone from goofy tree huggers to treasonous conspirators with America’s worst enemies. Now the Houthis, who brought slavery back to Yemen — among other charming progressive ideals — are the darlings of the far left. We must stop this idiocy before we surrender the country to these lunatics. Jeff a…

1
EP 117: Wendy Chung: whole genome newborn screening and other big opportunities in genomic medicine. 47:51

8M ago47:51

47:51

Summary: 0:00 Introduction 1:45 Wendy’s early career looking into the genetics of diabetes through mouse models 6:23 A high altitude view: Cutting through hype to spot the next wave of game-changing technology 8:03 The role of policy and communication: how Wendy’s work goes beyond the lab to create real-world impact 11:20 Wendy’s choice to do an MD…

1
EP 116: Genetics and Medicine: Clonal hematopoiesis, genomics in healthcare, and a new discovery in APOL1 kidney disease with Dr. Alex Bick 52:34

8M ago52:34

52:34

0:00 Introduction 4:23 Insights into clonal hematopoiesis from the pioneering Framingham Heart Study 8:30 Linking clonal hematopoiesis to cancer and cardiovascular health 11:22 Interplay of germline and somatic variants in clonal expansion 17:20 How the rate of clonal expansion can provide insights into cancer and cardiovascular risk 19:00 How clon…

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Tony Mayo Podcasts

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