Dementia Matters is a podcast about Alzheimer‘s disease and other causes of dementia. Creator and host Dr. Nathaniel Chin interviews leading scientists and caregiving experts to bring listeners the latest in Alzheimer’s disease news, research and caregiver resources. Brought to you by the Wisconsin Alzheimer’s Disease Research Center, find show notes and more resources at adrc.wisc.edu/dementia-matters.
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Taking a Positive Approach to Dementia Care with Strategies from Teepa Snow
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51:35Caring for someone living with dementia can be both deeply meaningful and incredibly challenging. Finding effective ways to connect, communicate and provide support often requires shifting how we see and respond to changes in the brain. In honor of National Family Caregivers Month, renowned dementia care specialist Teepa Snow joins the podcast to s…
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A Guide to Grief: Strategies for Navigating Loss and Dementia
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29:51Grief is a complex topic for people with dementia, their loved ones, caregivers and doctors to navigate. Dr. Erica Srinivasan, an expert on the psychology behind grief, joins the podcast to discuss the different kinds of grief people can experience and share strategies and resources for addressing the grief associated with dementia. Guest: Erica Sr…
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Clarifying the Alzheimer’s Disease Clinical Trials Landscape
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29:52Clinical trials are essential for improving the lives of those diagnosed with Alzheimer’s disease and related dementias. With so many trials out there, it can be difficult for someone who’s interested in participating in research to know where to start. Dr. Jonathan Graff-Radford joins the podcast to discuss the ins and outs of clinical trials and …
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Making Sense of Microplastics: New Research Looks at How Microplastics Build Up in the Brain and Body
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31:00Microplastics are a growing concern in the field of environmental health, but their impact on the brain is only beginning to be understood. Joining the podcast to share the latest research on these tiny particles, which have been found in the brain and other parts of the body, is Dr. Matthew Campen, a leading researcher in the field whose work is h…
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Identifying and Addressing Changes in Decision-Making Ability with Capacity Testing
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37:04As an individual develops dementia, they may need support in many areas of their lives. One of these areas is decision-making, particularly regarding health care decisions, but how can someone or their loved one determine if they need support with decision-making? To answer these questions, Dr. Victoria Williams joins to discuss capacity and capaci…
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Mindfulness and Meditation Practices for Living with MCI
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26:30Receiving a diagnosis of mild cognitive impairment (MCI) or dementia can be an emotional and challenging experience. How can meditative practices support those living with MCI? Buddhist chaplain Sharon Lukert wrote her book, Until My Memory Fails Me, with the goal of sharing mindfulness and spiritual practices that have helped her since being diagn…
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Under the FTLD Umbrella: A Deep Dive into Frontotemporal Dementia
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38:30Frontotemporal lobar degeneration (FTLD) is one of the most common causes of dementia in individuals under the age of 60, yet it remains lesser known and often misunderstood. From the early symptoms to the challenges of diagnosis and treatment, FTLD presents unique hurdles for clinicians, researchers and families alike. Joining the podcast to discu…
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Helpful or Harmful? New Study Looks at the Impact of Technology Use on Cognition
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44:41Smartphones and technology are ubiquitous in nearly every aspect of our lives, but is technology helping or hurting us when it comes to memory and cognition? Dr. Jared Benge, neuropsychologist and associate professor from the University of Texas at Austin, joins the podcast to discuss his research into how technology and smartphone use impacts the …
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Facing the Facts: Looking at the Alzheimer’s Association’s 2025 Annual Report
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19:55What is the current impact of Alzheimer’s disease and related dementias on the United States? To best understand its significance in 2025, we can turn to the Alzheimer’s Association’s Alzheimer’s Disease Facts and Figures report, a comprehensive resource that highlights the effect of Alzheimer’s on individuals, care partners, health care profession…
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Paying the Price: The Cost of Dementia in 2025
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32:53How much does it cost to live with dementia in the United States? The hidden costs are often overlooked, but these numbers and trends are important to understand in order to inform the public and effectively allocate resources. Dr. Julie Zissimopoulos leads The United States Cost of Dementia Project, where they recently published a report on the to…
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Harnessing Habits: The Power of Routines on the Brain
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44:38Everyone has habits. Some are beneficial for brain health while others are less so, but it turns out that habits as simple as brushing your teeth at the same time each morning can help your brain adapt to changes from cognitive impairment. Dr. Gordon Giles joins the podcast to dive into the fascinating world of neurological rehabilitation and how b…
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Aging in Place: Addressing the Challenges of Living Alone with Dementia
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36:39It’s estimated that 4.3 million older adults across the United States live alone with cognitive impairment. How do these individuals navigate the challenges and concerns that arise due to these memory and thinking changes, and what recommendations are there to support them as they continue living independently? Dr. Elena Portacolone joins Dementia …
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Family Ties: How Family History Affects Alzheimer’s Risk
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36:52How important is one’s family history when determining Alzheimer’s risk? Returning guests Drs. Jessica Langbaum and Sterling Johnson discuss the latest research on family history and genetic risk factors and share their perspectives on the topic, specifically focusing on the role of the APOE gene as a risk factor. Guests: Sterling Johnson, PhD, lea…
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Explaining Dementia to Kids Through the Power of Children’s Books
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44:17Having a relative or loved one receive a dementia diagnosis can be challenging for families, especially for families with children. How can parents, guardians and other adults explain these complex memory and thinking changes to children in a way they’ll understand? One possible way – children’s books. Dr. Tomás León joins the podcast to discuss hi…
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Training the Next Generation: How the Research Education Component Supports Early Career Researchers
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28:40The Research Education Component (REC) focuses on educating, mentoring and training the next generation of researchers at the over 30 Alzheimer’s Disease Research Centers (ADRCs) across the United States, offering a range of fellowships, educational activities and events like the annual Alzheimer’s Disease and Related Dementias (ADRD) Research Day.…
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Talking about Tau: The Role of Tau PET Scans in Alzheimer’s Research and Care
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55:33Early detection is a top priority in the field of Alzheimer’s research, and one indicator of Alzheimer’s disease is the buildup of tau in the brain. What is tau, though? How can we detect this protein, and what can it tell us about a person’s symptoms or disease progression? Dr. Gil Rabinovici, a leader in the field of brain imaging, joins Dementia…
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Changing the Narrative: One Man’s Journey to Alzheimer’s Diagnosis and Treatment
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28:50Receiving a diagnosis of Alzheimer’s disease or a related dementia can be a complicated experience. While some experience relief at being able to put a name to their concerns, many worry about telling loved ones or being treated differently due to the stigma surrounding the word “dementia.” Mike Zuendel joins the podcast to share his experience of …
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A Pathway to Wellness: The Benefits of Integrative Medicine on Brain Health
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29:58Holistic medicine, alternative medicine, complementary medicine – you may have heard these terms or seen them used online and wondered what they mean. Each term refers to the concept of integrative medicine, a comprehensive approach to healthcare that focuses on treating a person’s mind, body and spirit rather than addressing symptoms or a specific…
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Putting a ‘Spotlight on Care’: Caregivers Help Other Caregivers Through Podcast Series
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40:10Caring for a loved one with Alzheimer’s disease or a related dementia can be challenging, with no two journeys being the same. Who better to turn to for caregiving support, tips and advice, then, than other caregivers who have been on similar paths? Steve O’Leary and Virginia Naeve join Dementia Matters to share their different experiences caring f…
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Shining Light on Younger-Onset Dementia with Lorenzo’s House
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41:02Dementia diagnoses affect families in many different ways. One of the most challenging to navigate is that of younger-onset dementia (YOD), a form of dementia that affects someone below the age of 65. This diagnosis can be particularly jarring for young families, as resources, support and research for this form of dementia are limited. When Diana C…
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What Now? Next Steps After Receiving an MCI Diagnosis
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44:42What exactly does a mild cognitive impairment (MCI) diagnosis mean, and what should you do after receiving one? Hearing this diagnosis from a doctor can bring up a lot of emotions and questions for individuals and family members. Jennifer McAlister joins Dementia Matters to offer advice for next steps after receiving an MCI diagnosis and share stra…
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While there are many kinds of dementia, like Alzheimer’s disease and Lewy body dementia, there’s one that researchers have only recently identified. LATE, or Limbic-predominant Age-related TDP-43 Encephalopathy, is a newly-characterized type of dementia associated with abnormal clumps of a protein called TDP-43. So, what exactly do we know about LA…
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‘Tis the Season: Navigating the Holidays as a Dementia Caregiver
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21:28The holidays can be a stressful time for everyone, especially those with dementia and their care partners. In preparation for this season, Dr. Alexis Eastman joins Dementia Matters for our last episode of 2024. Drs. Chin and Eastman discuss strategies for managing the potential stress of holiday traveling and gatherings, important safety considerat…
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Could AI Identify Alzheimer’s Risk Factors from Electronic Health Records?
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34:51With the recent surge in artificial intelligence and machine learning technology, one of the most exciting fields it could revolutionize is health care and, more specifically, the field of cognitive care and research. Dr. Marina Sirota and Alice Tang join the podcast to share their research on how AI could be used to predict one’s risk of developin…
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The Future of Fluid Biomarkers for Alzheimer’s Disease and Related Dementias
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38:41The field of biomarkers is constantly evolving, leading to developments in diagnosing and treating different kinds of dementia, but what exactly are biomarkers and how has our understanding of these measures changed over time? Dr. Henrik Zetterberg joins Dementia Matters to talk about the latest updates in research on fluid biomarkers. Dr. Zetterbe…
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Support for the Supporters: Resources for Alzheimer’s Caregivers
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29:48If you're one of the 11 million Americans providing unpaid care to a loved one with Alzheimer’s disease, you know that caregiving is both incredibly rewarding and challenging. What makes caring for someone with dementia so emotionally and physically demanding, and what resources and strategies are available to help? In this episode, Bonnie Nuttkins…
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Smartphone Screenings: Assessing Memory and Cognition using a Mobile App
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31:45What if you could test your cognition from the comfort of your own home using a smartphone? Drs. David Berron and Lindsay Clark have spent years researching cognitive neuroscience, culminating in a 2024 published study investigating the effectiveness of a smartphone app as a tool for detecting cognitive impairment outside of a clinic or research se…
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Catch Some Zzz’s: The Cognitive Benefits of Quality Sleep
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33:35If you get the recommended eight hours of sleep per night, you spend a third of your life asleep. Why dedicate so much time to sleeping, and how can one get the most out of those eight hours? In this episode, Dr. Allison Reiss joins us for an insightful conversation about how sleep helps the brain, what the brain does while we are asleep, tips for …
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Taking a Closer Look at Cognitive Decline and Preclinical Alzheimer’s Disease
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24:26Dr. Reisa Sperling returns for another episode of Dementia Matters. After covering her research focused on preclinical Alzheimer’s disease in part one, Dr. Sperling dives deeper into the different factors that can impact cognitive decline and early-stage Alzheimer’s disease and how clinical trials are shaping the field’s understanding of detecting,…
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Defining and Addressing Preclinical Alzheimer’s Disease
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21:49What if there was a way to detect Alzheimer’s disease before clinical signs and symptoms even appeared? Dr. Reisa Sperling joins Dementia Matters for a two-part series covering her research on detecting and treating Alzheimer’s disease at the earliest possible stage, known as preclinical Alzheimer’s. In this episode, Dr. Sperling goes in-depth on a…
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Gut Feelings: The Links Between Gut Health and Alzheimer’s Disease
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33:32An expanding field of research is looking at how the gut affects different parts of people’s health, but how does it affect brain health? Drs. Barb Bendlin and Tyler Ulland join the podcast to talk about their 2023 study, which suggests a link between gut health, aging and changes related to Alzheimer’s disease. They discuss their findings on how g…
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Reviewing the Six Pillars of Brain Health
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45:57In this compendium episode, we review some of the best information and research that we’ve shared on the six pillars of brain health. With excerpts highlighting the importance of physical activity, diet, sleep, social engagement and more, our six guests show that there are numerous evidence-based lifestyle interventions that a person can incorporat…
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Predictive Personalities: How Personality Traits Influence Dementia Risk
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37:15While genetics and lifestyle can influence one’s risk of developing Alzheimer’s disease, other unexpected factors can shift the possibility. One of these factors is personality. Dr. Emorie Beck joins Dementia Matters to share her research on the link between personality and Alzheimer’s risk. Dr. Beck breaks down the Big Five traits that make up som…
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Getting AHEAD of Alzheimer’s with Inclusive Clinical Trials
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25:19Dementia Matters Special Series: Voices of Research Participants When Ms. Carol Turner found out her family had a history of Alzheimer’s disease, she wanted to know how she could help herself and others with similar experiences. After learning about the AHEAD Study, which is testing a treatment that could delay memory loss before Alzheimer’s sympto…
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REVEALing APOE Results: Making Genetic Disclosures in Alzheimer’s Research
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35:00On this episode of Dementia Matters, Dr. Scott Roberts talks about disclosing genetic test results for APOE, a gene that can increase one’s likelihood of developing Alzheimer’s disease. While this information can be concerning, Dr. Roberts shares that it can empower individuals to take the necessary precautions to lower their risk of developing the…
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Advocating for All: The Impact of Community and Equity in Dementia Research
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32:45Dementia Matters Special Series: Voices of Research Participants What do you do when dementia symptoms begin to upend your entire life? For Brother John-Richard Pagan, the answer was to persist in finding a diagnosis and a supportive community that aligned with his values. In this episode of our Voices of Research Participants series with co-host S…
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Be BOLD: Detecting Dementia Early Through Public Health Initiatives
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33:38When it comes to dementia diagnoses, the earlier, the better, but why is it difficult to detect dementia in its early stages? Moreover, what strategies can be used to improve dementia detection? Dr. Josh Chodosh joins the podcast to answer these questions and discuss how public health initiatives could improve dementia diagnoses. He also talks abou…
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Let’s Talk: Navigating Family Conversations About Dementia Through Shared Decision-Making
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47:44Picture this: you are supporting someone experiencing memory changes as a clinician, support person or care partner while they go through the memory clinic process. How do you navigate the challenging conversations surrounding symptoms, diagnoses, care plans and more that come up? Dr. Toby Campbell joins the podcast to discuss the importance of sha…
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Making an IMPACT: Advancing Alzheimer’s Disease Clinical Trials Through Workforce Development and Inclusivity
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23:17Advances in Alzheimer’s disease clinical trials are accelerating rapidly, leading to new insights and disease-modifying therapies, but how does the field continue bolstering that momentum? For Dr. Rema Raman, it’s through improving inclusivity and training for early-career researchers. Recorded at the 2024 Alzheimer’s Disease & Related Dementias Re…
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Living with Lewy Body: A Neurologist’s Journey Through Research and Dementia Care
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26:42What do you do if you have a family history of dementia and are experiencing symptoms, but can’t get a diagnosis? Dr. Sara Langer has dealt with just that. In the latest episode of our Voices of Research Participants series, Dr. Langer shares the obstacles she endured to receive her diagnosis of Lewy body dementia (LBD), how her background as a neu…
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The Fundamentals of Neuropsychology: Breaking Down Cognition, Memory and More
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41:52The brain is the most complex part of the human body, controlling thought, memory, emotion, motor skills, sensory input and all the processes that regulate our bodies. How exactly does it work, and how are clinicians able to determine whether brain changes are a result of normal aging, Alzheimer’s disease, or something else? Dr. Victoria Williams j…
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Since the COVID-19 pandemic was declared by the World Health Organization (WHO) in 2020, there have been many concerns about how cases of COVID-19 and Long COVID or Post-COVID Conditions (PCC) affect not just a person’s physical health, but their cognition as well. In this episode, Dr. Jim Jackson talks about his path into critical illness research…
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Listen Up! The Connections Between Hearing Loss, Hearing Interventions and Cognitive Decline
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38:52Hearing loss affects roughly 15.5% of Americans 20 years and older. While the majority of these individuals experience mild hearing loss, the prevalence and severity of hearing loss increases with age. What does this sensory change mean for dementia risk, and can this risk be prevented through interventions like hearing aids? Dr. Frank Lin joins th…
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From Caregiver to Research Participant: How One Woman’s Experience as a Dementia Caregiver Drew Her to Alzheimer’s Research
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35:20Caring for a loved one with cognitive decline can be challenging. While it is a labor of love, burnout is all but inevitable. In this episode kicking off our Voices of Research Participants series with co-host Sarah Walter, Cynthia Sierra touches on her personal experience with caregiver burnout as both a caregiver and research study partner for he…
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Looking at Lecanemab’s Eligibility Guidelines and Prescription Process
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35:57In the past few years, new therapies shown to slow the progression of Alzheimer's disease in people in the early stages of the disease have been making their way through the U.S. Food and Drug Administration’s (FDA) approval process. With these treatments now available, there are a growing number of questions surrounding who is eligible to take the…
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Do Non-Medicinal Interventions Reduce Dementia Risk? Studies are Inconclusive, Here’s Why
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34:34In 2017, the National Academies of Sciences, Engineering, and Medicine published a report showing promising but inconclusive evidence suggesting that interventions like cognitive training, blood pressure control and increased physical activity reduce a person’s risk for dementia, but what does the research show now? Dr. Luke Stoeckel from the Natio…
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The Road to Hope: Philanthropy’s Impact on Alzheimer’s Research
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24:53In this year-end episode of Dementia Matters, we explore the vital role of philanthropy in advancing Alzheimer's disease research and care. Mr. Dave Adam serves on the board of visitors for the UW Initiative to End Alzheimer’s (IEA) and is an avid long-distance biker. In this episode, Adam shares his journey of combining his passions for biking and…
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Could Green Tea Hold the Key to New Alzheimer’s Treatments?
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21:49Dr. Paul Seidler joins the podcast to discuss his recent study looking at the connection between molecules in green tea and tau proteins. He also discusses the impact those molecules have on preventing cognitive decline and how these findings could lead to new strategies for treating Alzheimer’s disease. Guest: Paul Seidler, PhD, assistant professo…
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The Impact of Social Isolation on Dementia Risk in Older Adults
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24:55In May 2023, the U.S. Surgeon General, Dr. Vivek Murthy, released an advisory calling attention to the public health crisis of loneliness and social isolation in the U.S. With this widespread issue affecting such a broad population, how does social isolation impact older adults? Dr. Alison Huang joins the podcast to share insights from her study on…
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Memories and Milestones: Celebrating Six Years of ‘Dementia Matters’
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22:21Six years following the start of Dementia Matters in October 2017, the podcast team turns the tables on our host, Dr. Nathaniel Chin. Producers Amy Lambright Murphy and Caoilfhinn Rauwerdink talk with Dr. Chin about how the podcast got started, the brain health tips he incorporates into his own life, how he envisions the field of Alzheimer’s diseas…
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