Best Blood And Platelets Podcast Podcasts (2024)

1
Pirtobrutinib plus venetoclax with or without rituximab in relapsed/refractory CLL; murine models of erythroid 5ALA synthesis disorders; targeting PKCa in diabetes and hemochromatosis 23:17

2h ago23:17

23:17

In this week's episode we’ll discuss the safety and efficacy of pirtobrutinib with or without rituximab in relapsed/refractory CLL; learn more about erythroid 5ALA synthesis disorders and their conditional synthetic lethal dependency on pyridoxine; and discuss how targeting PKC alpha alleviates iron overload in diabetes and hemochromatosis through …

1
EBB 329 - Q & A about Blood Types, Rh Incompatibility in Pregnancy, and the Rhogam Shot 52:00

2h ago52:00

52:00

In this episode, we're exploring the fascinating science of blood types and blood incompatibility in pregnancy. You’ll learn about the basics of blood types, how they are inherited, and why knowing your blood type is crucial—especially during pregnancy. Rebecca and Sara also discuss the implications of Rh incompatibility, ABO incompatibility, and o…

1
Transplant outcomes in pediatric Fanconi anemia; hepatic Foxo1 regulates iron homeostasis; clinical networks improve APL outcomes in Latin America 18:42

2h ago18:42

18:42

In this week's episode we'll discuss outcomes following hematopoietic stem cell transplantation in pediatric patients with Fanconi anemia. Then, we'll learn about how new research shows that the transcription factor Foxo1, commonly associated with glucose metabolism, regulates hepcidin expression and systemic iron homeostasis. Finally, in Latin Ame…

1
EBB 328 - Importance of Bilingual Doula Care with Neysha Reyes Cruz of Olas de Amor 56:35

1h ago56:35

56:35

Neysha Reyes Cruz’s journey to becoming a birth doula was sparked by witnessing the inadequate support and resources during a friend’s hospital birth in Puerto Rico. Her personal experiences and those of her family have further fueled her commitment and passion for advocating on behalf of women, particularly within Hispanic and Latinx communities. …

1
CD8+ T-cell differentiation and treatment response in AML; ATM germline pathogenic variants affect cancer outcomes in ataxia-telangiectasia; efficacy of a selective menin-KMT2A inhibitor in KMT2A- and ... 22:42

8d ago22:42

22:42

In this week's episode we’ll discuss how CD8+ T-cell differentiation and dysfunction inform treatment response in acute myeloid leukemia; learn more about the effect of ATM germline pathogenic variants on the outcomes in children with ataxia-telangiectasia and hematological malignancies; and discuss the preclinical efficacy of a potent, selective m…

1
EBB 327 - Latina Advocacy and Fighting the Maternal Mortality Epidemic in California with Kimberly Turbin and Michele Monserratt-Ramos of Consumer Watchdog 49:03

15d ago49:03

49:03

We are joined by Kimberly Turbin and Michele Monserratt-Ramos, staunch advocates against obstetric violence driven by personal experiences and a commitment to marginalized communities. Note: Read the transcript in English or español here! Or watch with closed captions on the EBB YouTube channel. Kimberly's advocacy began after a traumatic birth exp…

1
5 Questions with Dr. Anita Dhanrajani 11:54

14d ago11:54

11:54

5 Questions is a new series of Blood, Sweat and Smears, hosted by our Senior Director, Bjorn Stromsness, who asks 5 questions to physicians in and around the disease areas we work in. In this episode, we are joined by Dr. Anita Dhanrajani, a pediatric rheumatologist at Children's Hospital New Orleans, specializing in children with autoimmune diseas…

1
TCR-T cells for post-HCT leukemia recurrence; platelets are the predominant source of procoagulant membranes in hemostasis; BR + R maintenance for MCL 18:10

21d ago18:10

18:10

In this week's episode we'll discuss HA-1-targeted T-cell receptor T-cell therapy for recurrent leukemia after hematopoietic stem cell transplantation. Next, we'll learn about how 4D intravital imaging in mice reveals the key role of platelets as a source of procoagulant membranes in hemostasis. Finally, we'll hear about modifications to a common i…

1
EBB 326 - Reducing Toxin Exposure in Pregnancy and Postpartum with Lisa Smith, Dietitian, Holistic Nutritionist, and Gut Health Expert 44:10

21d ago44:10

44:10

Lisa Smith, a registered dietitian and host of the Pretty Well podcast, joins us on the EBB podcast to discuss the crucial topic of reducing toxins in the home during pregnancy and postpartum. Lisa shares her personal health journey, including her experience with Hashimoto's disease (an autoimmune condition impacting the thyroid), and highlights th…

1
Outcomes of younger patients with mantle cell lymphoma; M-protein assessment during maintenance therapy in multiple myeloma; in vivo CAR T-cell generation using lentiviral vectors 0:59

15d ago0:59

0:59

In this week's episode we’ll discuss the outcomes of younger patients with mantle cell lymphoma experiencing late relapse; learn more about mass spectrometry-based assessment of M-protein in peripheral blood during maintenance therapy in multiple myeloma and discuss in vivo CAR T-cell generation in non-human primates using lentiviral vectors. Featu…

1
Review Series on Factor XI 44:40

15d ago44:40

44:40

Introduced by Associate Editor Dr. Thomas Ortel, this bonus episode discusses the Review Series on Factor XI, published in volume 143 issue 15 of Blood Journal. Dr. Ortel is joined by contributing authors Owen McCarty, PhD, Gili Kenet, MD, and David Gailani, MD. Review Series Articles: Introduction to a review series on factor XI Biology of factor …

1
EBB 325 - Surviving HELLP Syndrome and Planning a VBAC in a Subsequent Pregnancy with Jolene Brink, EBB Childbirth Class Graduate 41:00

20d ago41:00

41:00

Following an emergency c-section due to HELLP syndrome in her first pregnancy, Jolene Brink was determined to have a different birthing experience with her second child. Through the support of a knowledgeable medical team and insights gained from her EBB Childbirth Class, she successfully achieved her goal of an unmedicated VBAC with the birth of h…

1
Protective role of neonatal CMV infection in B-ALL; GVHD targets organoid-forming bile duct stem cells; seven-year outcomes for venetoclax-ibrutinib therapy in MCL 16:56

22d ago16:56

16:56

In this week's episode we'll learn how cytomegalovirus infection early in life depletes preleukemic cells in a mouse model of B-cell acute lymphoblastic leukemia. After that we'll discuss new research, where GVHD targets organoid-forming bile duct stem cells in a TGF-beta-dependent manner. Conversely, a TGF-beta inhibitor protects these stem cells …

1
EBB 324 - Blending Birth, Science, Technology, and Storytelling with Erica Chidi, Co-founder and CEO of LOOM 29:40

1M ago29:40

29:40

Erica Chidi joins us to share her journey from working as a full-spectrum doula to becoming an educator and leader in women's health. With over a decade of experience, Erica discusses how her upbringing in a medical family, coupled with her unique approach to doula work, led her to create LOOM, a health information app designed to empower women and…

1
Iron, HFE haemochromatosis, and infections; bispecific antibodies improve CAR T-cell response; determinants of outcome in NPM1-mutated AML 23:31

29d ago23:31

23:31

In this week's episode we'll learn about iron, HFE hemochromatosis, and infections. In this large, population-based study, both high and low levels of plasma iron and transferrin saturation were associated with increased risks of infection. Then, we'll discuss how bispecific antibodies improve CAR T-cell response in B-cell malignancies. In-vitro an…

1
EBB 323 - Q & A on Frequent Air Travel in Pregnancy, Induction for Low Platelets, and Anterior vs. Posterior Placenta 40:24

1M ago40:24

40:24

In today's episode, we're diving into a mini Q&A session to address some pressing questions from our incredible EBB Pro Members. We'll explore the risks of radiation exposure during air travel in pregnancy, particularly for airline crew members. Then, we'll discuss the implications of low platelet counts and whether they necessitate induction. Last…

1
Immune fitness and response to taclistamab in R/R multiple myeloma; BCR::ABL1 M244V mutation causes resistance to asciminib; HSCT and myocardial fibrosis in young patients with SCD 16:59

1M ago16:59

16:59

In this week's episode we’ll discuss how immune fitness impacts response to teclistamab in relapsed/refractory multiple myeloma; learn more about a new mechanism of resistance to asciminib conferred by the BCR::ABL1 M244V mutation, and discuss the impact of hematopoietic cell transplantation on myocardial fibrosis in young patients with sickle cell…

1
EBB 322 - Harnessing the Power of the Mind to Enhance Joy and Comfort in Childbirth with Kerry Tuschhoff, Founder of Hypnobabies®️ 47:15

1M ago47:15

47:15

Kerry Tuschhoff, founder and director of Hypnobabies®, brings a wealth of experience as a childbirth educator, doula, speaker, and hypnotherapist to the realm of hypnobirthing. Inspired by her own challenging birth experiences and a TV show about hypnosis for childbirth, she meticulously studied hypnotherapy and pain management to develop Hypnobabi…

1
5 Questions with Dr. Gefen 11:17

2M ago11:17

11:17

5 Questions is a new series of Blood, Sweat and Smears, hosted by our Senior Director, Bjorn Stromsness who asks 5 questions to physicians in and around the disease areas we work in. In this episode, we are joined by Dr. Ashley Gefen, MD, a pediatric nephrologist specializing in genetic kidney diseases, tubular disorders, and kidney stone disease a…

1
Decitabine in older patients with AML; EPCR and sickle chronic kidney disease; lymphocyte depletion versus post-transplant cyclophosphamide for mismatched donor transplant for inborn errors of immunity ... 22:53

1M ago22:53

22:53

In this week's episode we’ll discuss the safety and efficacy of decitabine in older patients with AML; learn how heme-induced loss of renovascular endothelial protein C receptor promotes chronic kidney disease in sickle mice, and discuss the outcomes of treatment with HLA-mismatched HSCT with TCRab/CD19 lymphocyte depletion or post-HSCT cyclophosph…

1
EBB 321 - An Empowering, Trauma-Informed Home Birth with First-Time Mom and EBB Childbirth Class Graduate Iris Casey 56:46

2M ago56:46

56:46

Evidence Based Birth® Childbirth Class graduate Iris Casey is sharing her inspiring home birth story with Dr. Dekker. Iris opens up about her journey to motherhood, after grappling with the decision to become a parent and overcoming past traumas. She recounts the unexpected onset of labor, navigating the early stages with her supportive partner, an…

1
Impact of MRD-negative on PFS in myeloma; IPSS-R down-staging before transplant in MDS; hereditary angioedema and venous thromboembolism 21:50

2M ago21:50

21:50

In this week's episode we'll discuss minimal residual disease as an intermediate clinical endpoint for multiple myeloma. Then, we'll learn about IPSS-R downstaging before transplant in MDS. Finally we'll hear about the connection between hereditary angioedema and venous thromboembolism. Featured Articles: EVIDENCE meta-analysis: evaluating minimal …

1
EBB 320 - Evidence on the Impact of Epidurals on the Pushing Phase of Labor 22:40

2M ago22:40

22:40

The impact of epidurals on the second stage of labor has sparked a lot of discussion. Research suggests that epidurals can prolong this stage... and a prolonged second stage can be associated with increased risks of infection, severe tears and the need for interventions like forceps-assisted delivery or Cesarean. But does an epidural mean that you …

1
Acalabrutinib, venetoclax and obinutuzumab in relapsed/refractory CLL; alternative donor transplantation for severe aplastic anemia; clonal relapse dynamics in AML following allogeneic HCT 23:32

2M ago23:32

23:32

In this week's episode we’ll discuss the safety and efficacy of acalabrutinib, venetoclax and obinutuzumab in relapsed/refractory CLL; learn more about alternative donor transplantation for severe aplastic anemia and discuss clonal relapse dynamics in acute myeloid leukemia following allogeneic hematopoietic cell transplantation. Featured Articles:…

1
EBB 319 - Exploring Love and Intimacy in Birth with Debra Pascali-Bonaro, Founder of Orgasmic Birth 48:40

2M ago48:40

48:40

Dr. Rebecca Dekker's joined by Debra Pascali-Bonaro, host of the Orgasmic Birth podcast, to explore the connections between love, intimacy, and childbirth. A world-renowned speaker and doula trainer, and the creative force behind the documentary "Orgasmic Birth: The Best-Kept Secret," Debra shares her origins into the world of childbirth education …

1
5 Questions with Dr. Kopko 11:51

2M ago11:51

11:51

5 Questions is a new series of Blood, Sweat and Smears, hosted by our Senior Director, Bjorn Stromsness who asks 5 questions to physicians in and around the disease areas we work in. In this episode, we are joined by Dr. Patricia Kopko, a Professor of Pathology at UC San Diego, Director of Transfusion Medicine, and Associate Director of the Immunog…

1
Clinical impact of CRh in AML; thrombosis features in a real-life PNH cohort; and restriction of SOX11 expression to EBV-negative Burkitt lymphomas 19:58

2M ago19:58

19:58

In this week's episode we'll learn about the clinical benefit of complete remission with partial hematological recovery, or CRh, in patients with Acute Myeloid Leukemia (AML) treated with molecularly targeted drugs. Then we'll hear about a large cohort of patients with PNH were studied to detail PNH-related thrombotic events, unravel determinants o…

1
EBB 318 - Advocating for Waterbirth in Hospitals with Dr. Liz Nutter, DNP, CNM, and Retired Lieutenant Colonel 45:24

3M ago45:24

45:24

Dr. Liz Nutter, a retired Lieutenant Colonel with over 20 years of nursing and healthcare leadership experience, is bringing her expertise as a board-certified nurse midwife and national expert in waterbirth and hydrotherapy evidence-based practice. Dr. Nutter shares her journey from serving in the United States Army to becoming an assistant profes…

1
Mutational and transcriptional landscape of pediatric BCP lymphoblastic lymphoma; the role of platelet-derived TGF-1 in immune thrombocytopenia; phase 3 trial of mavorixafor in WHIM syndrome 23:25

2M ago23:25

23:25

In this week's episode we’ll discuss the mutational and transcriptional landscape of pediatric BCP lymphoblastic leukemia; learn more about the role of platelet-derived TGF-β1 in immune thrombocytopenia; and discuss the findings from a phase 3 trial of mavorixafor in WHIM syndrome. Featured Articles: Mutational and transcriptional landscape of pedi…

1
REPLAY: EBB 186 – A Positive Pregnancy and Birth Outcome with Multiple High-Risk Labels with EBB Childbirth Class Parent, Angela Jones 1:01:56

3M ago1:01:56

1:01:56

Today, we’re sharing a replay of our podcast episode with EBB Childbirth Class parent, Angela Jones, about having an uncomplicated pregnancy and birth when labeled as high risk. Angela is a macro-level social worker, wife to her husband, Tony, and mom to her son, Allister, and their cats, Pumpernickel and Lion-O. Angela and Tony graduated from the …

1
Review Series on Oncogenic Signaling and Immune Evasion in Hematologic Malignancies 15:41

3M ago15:41

15:41

Introduced by Associate Editor Robert Zeiser, this Review Series focuses on the problem of immune escape by acute myeloid leukemia (AML). The series opens with a review of how AML escapes T-cell–driven elimination and then focuses on how p53 function impinges on AML recognition by immune cells. The series finishes with a summary of new approaches t…

1
GM-CSF coordinates shelter in the cytokine storm; Interleukin-1 as a therapeutic target in TTP; CAR T-cell outcomes across race and ethnicity in LBCL 19:57

3M ago19:57

19:57

In this week's episode we'll discuss new insights on the role of GM-CSF in establishing immune memory. The authors propose that the coordination of opposing immune memory programs, driven by GM-CSF, may be essential to efficient, yet controlled, innate immune responses. After that: Interleukin-1 inhibition in TTP. Researchers explore the potential …

1
EBB 317 - Evidence on Epidurals for Pain Management during Labor 42:01

3M ago42:01

42:01

Have you ever wondered what the evidence is on epidurals for pain management during labor? Join us on today’s podcast as we discuss most recent evidence on epidurals, spinals, and combined spinal-epidurals! We’ll begin with some background on these methods, including how common they are in the U.S. and around the world, before moving on to the effe…

1
What's the deal with Liver Enzymes with Dr. William Carey, MD 30:55

3M ago30:55

30:55

In this episode of the Medicine Grand Rounders, Dr. William Carey takes a deep dive into how to deal with elevated liver enzymes.By Internal Medicine Residency Program

1
Reassessing the CLL prognostic index; ADAMTS13 conformation and risk of relapse in immune-mediated TTP; haploidentical bone marrow transplant in sickle cell disease 23:39

3M ago23:39

23:39

In this week's episode we’ll discuss the prognostic value of the Chronic Lymphocytic Leukemia International Prognostic Index in the era of targeted therapies, learn how peak ADAMTS13 activity can be used to assess ADAMTS13 conformation and risk of relapse in immune-mediated thrombotic thrombocytopenic purpura, and discuss the findings from a phase …

1
A biomarker for disease severity in Wiskott-Aldrich Syndrome; loss of Dnmt3a confers resistance to IFNα; unrelated donor selection in HSCT with PTCy 19:16

3M ago19:16

19:16

In this week's episode we'll discuss assessing risk profile in Wiskott-Aldrich Syndrome, or WAS. Then, we'll learn about how the loss of DNMT3A confers resistance to interferon-alpha in hematopoietic stem cells carrying the JAK2-V617F mutation. Finally, we'll explore unrelated donor selection for AML patients undergoing hematopoietic stem cell tran…

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