Rheumatology is an incredibly fast-moving and exciting field of medicine that can be difficult to keep up with. This podcast provides busy clinicians with quick updates in the field of autoimmunity, with emphasis on new medications, treatment guidelines and explorations into the pathophysiology of diseases. The show will also feature historical perspectives in the field of rheumatology, as well as fascinating case presentations of medical mysteries complete with discussions from experts in t ...
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MedEdTalks Rheumatology is an accredited educational podcast for providers to learn more about treating patients with Rheumatology diseases/disorders. Discover all content and topics, by visiting mededtalks.com.
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Urticarial Vasculitis, Part 2: Walking the Balance Beam of Allergy and Rheumatology
35:59
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This episode digs into the pathophysiology of urticaria vasculitis from anti-C1q to the story of bradykinin. · Intro 0:11 · In this episode 0:22 · Review of episode 83 1:23 · Listen to previous episode, The Complement System for Dunces 4:09 · Anti-C1q antibodies 6:26 · Lupus, anti-C1q and lupus nephritis 9:33 · What happens when you inject anti-C1q…
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Urticarial Vasculitis: Attack of the Nettles, Part 1
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Is it an allergy or an autoimmune vasculitis, or a little of both? Find out the story of urticarial vasculitis, how this disease was recognized and eventually sorted out from other types of urticaria. · Intro 0:12 · In this episode 0:21 · Case study 1:22 · Chronic spontaneous urticaria, hives and nettles 7:57 · Dermatographism and witchcraft? 10:15…
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COVID-19, long COVID and the rheumatologist with Leonard Calabrese, DO
29:04
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What should rheumatologists know about what we've learned about COVID-19 and long COVID in 2023? Hosted by Dr. Leonard Calabrese. · Intro 0:11 · In this episode 0:21 · 2023: current status and controversies 0:35 · What is going on with COVID-19? 01:53 · What do we know about vaccine responses? What should we be telling our patients about vaccines i…
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Recent Updates on Management of Uncontrolled Gout, With Drs. Suneet Grewal, Puja Khanna, and Michael Pillinger
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24:01
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In this podcast, clinical experts discuss key findings presented during the past year on current and emerging therapies for managing uncontrolled gout.
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Evidence-Based Tools to Detect and Assess Uncontrolled Gout, With Drs. Suneet Grewal, Puja Khanna, and Michael Pillinger
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18:04
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In this podcast, clinical experts discuss key findings presented during the past year on evidence-based tools for detection and assessment of uncontrolled gout.
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Burden and Complications of Uncontrolled Gout, With Drs. Suneet Grewal, Puja Khanna, and Michael Pillinger
21:11
21:11
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In this podcast, clinical experts discuss key findings presented during the past year on disease burden and comorbidities associated with uncontrolled gout.
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It's that time of year again, everyone rolling up their sleeves to get a flu shot. This episode dives into the history of the struggles pinning down the causative agent of flu and the journey to the vaccine! · Intro 0:12 · In this episode 0:17 · The history of the flu: 1892 3:10 · Rabies and dead virus 10:52 · A Sickness in the Serum, Part 2 14:31 …
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It's in the Air: Silica exposure and the risk of autoimmunity, Part 4
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23:38
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What is silica? How does it impact your risk of developing autoimmunity if you inhale it, inject it or even snort it up your nose? Listen and find out! · Intro 0:12 · In the previous episodes 0:28 · The Ajax incident of 1979 1:15 · Silica and its association with autoimmune disease 4:11 · The history of silica and the health risks 5:21 · Rheumatoid…
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In this episode, we dig through the data of lupus in Africa and speak with experts on the Lupus Gradient, the impact of malaria and what we can learn from it all. · Intro 0:12 · In the previous episode 0:30 · Lupus Gradient 2:01 · Back to Dr. Brian Greenwood 3:48 · Polyarthritis 4:04 · Rates of autoimmune diseases 6:00 · Malaria and mouse models 7:…
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Updates on Emerging Options for PrEP and COVID-19 Management in Immunocompromised Patients, With Drs. Leonard Calabrese and Kevin Winthrop
17:56
17:56
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In this podcast, expert clinicians will discuss the current tools available for outpatient management of COVID-19 and provide updates on emerging options for preexposure prophylaxis.
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This episode delves into what we can learn about the impact of the environment on autoimmunity, digging into how rates of autoimmunity can vary drastically in different parts of the world. · Intro 0:12 · In this episode 0:16 · Dr. Brian Greenwood 0:22 · The geography of autoimmunity 7:01 · Type 1 diabetes 10:31 · Finland and type 1 diabetes 13:57 ·…
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Outpatient Management of COVID-19 in Immunocompromised Patients: Educating the Patient, With Drs. Leonard Calabrese and Cassandra Calabrese
14:30
14:30
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In this podcast, expert clinicians will discuss current unmet needs regarding patient education and review strategic messaging to enhance the preparedness of immunocompromised patients at risk for COVID-19.
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This episode delves into the history of the hygiene hypothesis. What do we know about different exposures changing risk for asthma and allergies, and do these exposures have the same protection for autoimmunity? · Intro 0:12 · In this episode 0:18 · Hygiene hypothesis 0:33 · Allergic rhinitis (or Hay fever) 2:32 · Pollen and the allergy skin test 8…
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An Afternoon with the Glaucomfleckens: On hypermobility and physician burnout
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46:01
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On this special episode of Rheuminations, I interview comedian and ophthalmologist William Flanary, MD, and Kristin Flanary, also known as the Glaucomfleckens, on hypermobility and physician burnout. Kristen Flanary highlights what it's like to live with hypermobility, and Dr. William Flanary discusses his thoughts on physician burnout and using th…
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Outpatient Management of COVID-19 Immunocompromised Patients: Educating the Practitioner, With Drs. Leonard Calabrese and Myron Cohen
16:00
16:00
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In this podcast, expert clinicians will discuss outpatient management of COVID-19 and strategies to educate practitioners on best practices for those caring for immunocompromised patients.
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COVID-19 Disease Behavior in Immunocompromised Patients, With Drs. Leonard Calabrese and Alfred Kim
15:30
15:30
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In this podcast, expert clinicians will discuss how immune compromising conditions and iatrogenic causes of immune suppression affect risk for infection and severe outcomes with COVID-19.
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Case Discussions: Treating EGPA and Addressing Patient Concerns, With Drs. Leonard Calabrese and Adam Brown
14:29
14:29
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In this podcast, expert clinicians will review clinical cases of varying severity to highlight evidence-based approaches for management of EGPA.
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EGPA Management Updates, With Drs. Leonard Calabrese and Michael Putman
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15:13
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In this podcast, expert clinicians will discuss evidence-based practices on the appropriate use of glucocorticoids, immunosuppressants, and targeted therapy for induction and maintenance of remission in severe and non-severe forms of EGPA.
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Differential Diagnostic Considerations for EGPA, With Drs. Leonard Calabrese and Anisha Dua
16:51
16:51
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In this podcast, expert clinicians will examine diagnostic approaches that can be used to distinguish EGPA from other vasculitides and hypereosinophilic conditions.
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Immunopathology, Clinical Manifestations, and Burdens of EGPA, With Drs. Leonard Calabrese and Adam Brown
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14:26
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In this podcast, expert clinicians will review the underlying immunopathology and various clinical presentations of EGPA and discuss its impact on patient quality of life.
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Clinical Evidence for COVID PrEP, With Drs. Leonard Calabrese and Myron Cohen
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19:42
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In this podcast, expert clinicians will review recent developments involving monoclonal antibody therapies for COVID-19 and discuss ongoing studies on pre-exposure prophylaxis for immunocompromised patients.
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Was your psoriasis caused by the Black Death? Learn more than you might have wanted to know about the Black Death and delve into the data on the immunologic/autoimmune ramifications of wiping out nearly half of Europe. · Intro 0:11 · In this episode 1:09 · The Black Death 1:24 · The History of IV Immunoglobulin episode 2:07 · How the Black Death ha…
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Emerging Steroid-Sparing Options in Systemic Lupus Erythematosus, With Drs. Calabrese, Littlejohn, and Grewal
22:54
22:54
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In this podcast, expert clinicians will review a challenging case of systemic lupus erythematosus and discuss new or emerging therapeutic options that may be of benefit.
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New Steroid-Sparing Approaches for Vasculitis, With Drs. Calabrese, Brown, and Fuchs
25:20
25:20
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In this podcast, expert clinicians will review a challenging case of vasculitis and discuss new or emerging therapeutic options that may be of benefit.
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Incorporating Recent Advances in Psoriatic Arthritis, With Drs. Calabrese, Husni, and Koenig
24:48
24:48
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In this podcast, expert clinicians will review a challenging case of psoriatic arthritis and discuss new or emerging therapeutic options that may be of benefit.
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Understanding COVID-19 PrEP: Challenges and Opportunities, With Drs. Leonard Calabrese and Cassandra Calabrese
15:07
15:07
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In In this podcast, expert clinicians will discuss recent developments involving COVID-19 PrEP as well as current challenges and opportunities.
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Vascular Ehlers Danlos Syndrome for the Rheumatologist, Pt 2: Extra-Cellular Matrix Reloaded
41:57
41:57
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In this episode we explore ways in which the extracellular matrix can be manipulated, including the story of doxycycline, TGF-beta in Marfan syndrome and whether beta blockers can reduce vascular events in vascular EDS. · Intro 0:12 · Review of previous episode 0:28 · In this episode 2:26 · The pressure against the vessels 4:06 · The pressure again…
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Dive into vascular Ehlers-Danlos syndrome. What is it? How does it present? Get clues to its diagnosis and learn more about collagen than you ever wanted to know. Intro 0:12 In this episode 0:17 Why vascular Ehlers-Danlos syndrome? 0:28 Case study: Dr. Mories 2:20 What can we learn about vascular Ehlers-Danlos syndrome? 05:02 Collagen and elastin 0…
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Making Sense of Sensory Ganglionopathies, Part 2
29:24
29:24
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In this episode, Dr. Benjamin Claytor walks us through his approach to suspected sensory ganglionopathies. I also cover other neurologic complications of Sjogren’s syndrome and some interesting history on vitamin B6. Intro 0:12 In this episode 0:46 Neurologic complications of Sjogren’s Syndrome 1:55 Intro of Dr. Benjamin Claytor 6:00 The interview …
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Making Sense of Sensory Ganglionopathies and Sjogren’s Syndrome
37:36
37:36
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A sensational (or lack thereof) series on the signs and symptoms of the spellbinding sensory ganglionopathies. Intro :12 Today’s episode :16 Anatomy review 1:32 Large fiber vs. small fiber nerves 4:47 Case presentation 6:11 Neurologic examination of patient 8:31 What is pseudoathetoid posturing? 10:11 What does it mean to be length independent? 14:…
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Cytokine Signaling and Signatures: A New Approach With Drs. Grace Wright and Iain McInnes
15:21
15:21
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In this podcast, expert clinicians will discuss the promise of identifying and targeting the dominant cytokine networks active in the various disorders of IMID.
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Janus Kinase Inhibitor Safety Update With Drs. Grace Wright and Kevin Winthrop
12:46
12:46
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In this podcast, expert clinicians will review recent updates in the safety data regarding Janus kinase (JAK) inhibitors and discuss the appropriate selection of candidates for safe and effective use of JAK inhibitor therapy.
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IL-23/IL-17 Pathway in Inflammatory Skin and Joint Disease With Drs. Grace Wright and Kevin Winthrop
10:22
10:22
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In this podcast, expert clinicians will discuss the safety and efficacy of interleukin-17/23 inhibitors for the management of inflammatory skin and joint diseases.
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Long COVID: Some facts, unanswered questions and implications for rheumatology – Part 2
24:19
24:19
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In part two, Leonard Calabrese, DO, discusses the symptoms of long COVID and the role that rheumatologists play in diagnosing and treating patients with long COVID. Brought to you by Tremfya. Intro 1:06 Calabrese introduction 1:11 In this episode 1:36 Defining long COVID 1:49 Reviewing symptoms of long COVID 2:51 Long COVID fatigue 3:44 Studies and…
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Long COVID: Some facts, unanswered questions and implications for rheumatology – Part 1
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21:21
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In this episode, Leonard Calabrese, DO, reviews the history and controversies of post-infection sequelae, as well as the facts and epidemiology of long COVID. Intro :12 Calabrese introduction :15 COVID-19 and the history of modern medicine :48 In this episode 1:39 The course of COVID-19 2:05 COVID-19 vaccines and immunity 2:50 Controversy, facts, f…
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How is the synovial fluid produced? Who figured it out? It’s a ripping yarn involving corpses, cats, anti-hypertensives, steroids and streptococcus. Brought to you by Tremfya. Intro :11 Today’s episode :15 Synovium 101 :22 Overview of the synovium and synovial fluid 2:06 How they figured it out? Dr. Marian Ropes 5:37 Investigating synovial fluid 7:…
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SAPHO Part 2: An Abundance of Acronyms (AAOA)
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44:07
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What does the PAPA spectrum disorder teach us about SAPHO? Is SAPHO an autoinflammatory condition or part of the SpA spectrum? Why have antibiotics been used to treat this condition? Find out in this episode! Brought to you by Tremfya. Intro :01 Welcome to another exciting episode of Rheuminations :11 About today’s episode :17 A summary of SAPHO Pa…
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What is SAPHO? What does the ‘H’ stand for, again? This episode explores some basics about the condition and delves into the history of how this disease came to be. Intro :01 Welcome to another exciting episode of Rheuminations :11 About today’s episode :17 What does the acronym ‘SAPHO’ stand for? :37 How do you define this condition? 2:35 So, what…
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The Glucocorticoid Toxicity Index with John Stone, MD, MPH
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36:11
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Glucocorticoids can do a lot of harm over time. In this episode, John Stone, MD, MPH, walks us through the Glucocorticoid Toxicity Index (GTI), a validated tool to measure steroid toxicity over time that we’ll be seeing more of in the future. Intro :11 Stone introduction :26 About the GTI 1:13 Professional development opportunities for rheumatologi…
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A Patient With COVID-19 Experiencing Hyperinflammation
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13:10
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In this Curbside Consults video, Drs. Calabrese and Cron discuss the case of a young adult with COVID-19 who experiences serious complications due to hyperinflammation.
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A Newly Admitted Patient with COVID-19 and Worsening Respiratory Symptoms
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12:44
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In this Curbside Consults video, Drs. Calabrese and Tien discuss the workup and management of a 79-year-old man who is admitted to the hospital with rapidly worsening COVID-19 pneumonia.
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A Patient Presenting to the ED with Mild COVID-19
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13:14
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In this Curbside Consults video, Drs. Calabrese and Tien discuss the workup and management of a 72-year-old man presenting to the emergency department with a mild-to-moderate case of COVID-19.
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Primer on the Immune-Basis of COVID-19 Progression
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In this Curbside Consults video, Drs. Calabrese and Cron discuss the latest understanding of COVID-19 immunopathogenesis and potential therapeutic targets.
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A Cat in Wolves' Clothing, Part 3: An ID Perspective
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In this episode, Cassandra Calabrese, DO, dual-boarded in infectious disease and rheumatology, walks us through when to suspect Bartonella (it’s not always a house cat!), how to diagnose and how to treat. Intro :01 Welcome to another exciting episode of Rheuminations :11 About today’s episode :17 10th Annual Basic and Clinical Immunology for Busy C…
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A Cat in Wolves' Clothing, Part 2: The History of Bartonella
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37:52
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Is this episode clinically relevant? No. Is it important? I think so! The story of Bartonella features a cast of characters, including a medical student who died trying to understand the disease, as well as some scientists with some less than ethical experiments. Enjoy! Intro :01 Welcome to another exciting episode of Rheuminations :11 About today’…
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A Cat in Wolves’ Clothing: Bartonella and the Rheumatologist
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29:21
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Bartonella is an important mimic of a variety of autoimmune diseases, and it can be subtle. This episode tackles the ways in which this strange organism can present to a rheumatologist. Brought to you by Genentech Intro :01 Today’s episode :15 Overview of Bartonella 1:57 Inspiration for this episode 4:17 Bartonella, what are you? 7:24 About Bartone…
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Paget's and the Rheumatologist: Why Haven't I Seen This Yet?
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What is Paget’s? Why is it declining across much of the globe? Find out, plus hear an interview with the head of the center for osteoporosis and metabolic bone disease at Cleveland Clinic, Chad Deal, MD. Brought to you by GSK. Intro :11 Today’s episode :27 What is Paget’s? 1:07 The history of Paget’s 5:35 How often is this symptomatic? 9:30 The epi…
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A Sickness in the Serum, Part 3: The Search for Immune Complexes
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32:28
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The final episode in this trilogy delves into the advancement in laboratory techniques that allowed for more accurate measurements of immune complexes, leading to studies in the ‘50 and ‘60s that clearly demonstrated the potential pathogenicity of immune complex-mediated disease. Brought to you by GSK. Intro :20 Recap and in this episode :40 The pr…
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A Sickness in the Serum, Part 2: The Birth of Immune Complex Disease
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The second episode in the series delves into the experiments and observations of Dr. Clemens (Baron) von Pirquet who first proposed that antibodies and antigens join forces to wreak havoc. Brought to you by GSK. Intro :10 Today’s episode :26 A recap of the previous episode :43 About Baron von Pirquet 4:40 What’s going on in the study of infectious …
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A Sickness in the Serum, Part 1: Serum Sickness and the Rheumatologist
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This episode delves into the clinical presentation of serum sickness along with a dash of Arthus reaction, to boot! Brought to you by GSK. Intro :10 Today’s episode :26 Let’s get into some cases 4:11 The Arthus reaction 6:06 What is another example of the same thing happening but on a systemic level? 7:25 Breaking down the clinical features of seru…
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