Alexander Disease Research Update - Episode #12: GFAP variants and oxidative stress/mitochondrial dysfunction; commentary on dizziness, risks of brain biopsies
Manage episode 339901941 series 2952470
Albee Messing, Rachel Battaglia, and Abby Olsen discuss the following recent publication:
[01:00] Alexander disease GFAP R239C mutant shows increased susceptibility to lipoxidation and elicits mitochondrial dysfunction and oxidative stress (Redox Biology, 55:102415, 2022)
[14:23] Questions from email regarding 1) dizziness and 2) risks of brain biopsies.
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