066: IgA Deficiency and Anaphylactic Reactions with Jerry Sandler

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Manage episode 231037057 series 1220849
By Joe Chaffin, MD, Joe Chaffin, and MD. Discovered by Player FM and our community — copyright is owned by the publisher, not Player FM, and audio is streamed directly from their servers. Hit the Subscribe button to track updates in Player FM, or paste the feed URL into other podcast apps.

Here's what we thought we knew: IgA deficiency leads to anaphylactic transfusion reactions. Not so fast! Dr. Gerald Sandler from Georgetown University noticed something when he was in charge of one of the US national reference labs: Hardly anyone with true anaphylactic reactions actually had IgA deficiency and anti-IgA! There's more to the story, and Jerry is here to share it with us (including why it's still ok to look for IgA deficiency in these patients).

93 episodes