Manage episode 239415042 series 2529779
We investigate the claim that an alternative antibiotic to cephalosporins (e.g., cefazolin) should be selected for penicillin-allergic patients in the perioperative setting.
Claim 1. Alternative antibiotics may be as efficacious in preventing surgical site infections
Claim 2. Cephalosporins (e.g., cefazolin) may be unsafe due to cross-reactivity.
Claim 3. Administering cephalosporins (e.g., cefazolin) may be against the standard of care.
My guest this week is Dr. Matthew Vanneman, an attending cardiothoracic anesthesiologist at the Massachusetts General Hospital.
Full show notes available at depthofanesthesia.com.
Connect with us @DepthAnesthesia on Twitter or firstname.lastname@example.org.
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Music by Stephen Campbell, MD.
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Blumenthal KG, Ryan EE, Li Y, Lee H, Kuhlen JL, Shenoy ES. The impact of a reported penicillin allergy on surgical site infec- tion risk. Clin Infect Dis. 2018;66:329–336.
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Zagursky RJ, Pichichero ME. Cross-reactivity in β-lactam allergy. J Allergy Clin Immunol Pract. 2018;6:72–81.e1.
By listening to this podcast, you agree not to use information as medical advice to treat any medical condition in either yourself or others, including but not limited to patients that you are treating. Opinions expressed are solely those of the host and guests and do not express the views or opinions of Massachusetts General Hospital.