Thoughts About Hydroxychloroquine For COVID19 (March 2020)

Heme Review

This episode was recorded on and is current up to Friday March 27 2020.

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Papers described in show:

- Hydroxychloroquine and azithromycin as a treatment of COVID-19: results of an open- label non-randomized clinical trial. Gautret et. al. (Google Doc: https://drive.google.com/file/d/186Bel9RqfsmEx55FDum4xY_IlWSHnGbj/view, version as preprint submission: https://www.sciencedirect.com/science/article/pii/S0924857920300996)

- Statistical review of Hydroxychloroquine and azithromycin as a treatment of COVID-19: results of an open-label non-randomized clinical trial. https://zenodo.org/record/3724167#.Xn7LRy2ZPAy

- White NJ. The treatment of malaria. N Engl J Med. 1996;335(11):800.

- Warhurst DC et. al. Hydroxychloroquine is much less active than chloroquine against chloroquine-resistant Plasmodium falciparum, in agreement with its physicochemical properties. J Antimicrob Chemother. 2003;52(2):188. Epub 2003 Jul 1.

- Metal Ionophores- An Emerging Class of Anticancer Drugs. https://iubmb.onlinelibrary.wiley.com/doi/full/10.1002/iub.253

- Chloroquine is a Zinc Ionophore. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4182877/#pone.0109180-Ding1

- Treatment of Severe Chloroquine Poisoning. https://www.ncbi.nlm.nih.gov/pubmed/15837026

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Video by Chubbyemu:

A Man Drank 1 Bottle Rubbing Alcohol For COVID-19. This Is What Happened To His Brain: https://youtu.be/BMSgoppbXiU