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Sex-specific effects of prenatal opioid exposure

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Manage episode 353692260 series 1118500
Content provided by Nature Publishing Group. All podcast content including episodes, graphics, and podcast descriptions are uploaded and provided directly by Nature Publishing Group or their podcast platform partner. If you believe someone is using your copyrighted work without your permission, you can follow the process outlined here https://player.fm/legal.

Neonatal opioid withdrawal syndrome (NOWS) represents a major public health problem in the US with a high socioeconomic burden. The pathophysiology of this condition is not yet fully understood. Data from animal models have shown that opioids modulate brain reward signalling via an inflammatory cascade, however no such data exist for opioid-exposed neonates.


In this episode of Pediapod we meet Early Career Investigator Elizabeth Yen, an assistant professor of pediatrics at Tufts University School of Medicine. She recently published a pilot study which looked at the effects of prenatal opioid exposure on gene expression and white matter injury.


Read the full study here: Sex-specific inflammatory and white matter effects of prenatal opioid exposure: a pilot study | Pediatric Research (nature.com)



Hosted on Acast. See acast.com/privacy for more information.

  continue reading

113 episodes

Artwork
iconShare
 
Manage episode 353692260 series 1118500
Content provided by Nature Publishing Group. All podcast content including episodes, graphics, and podcast descriptions are uploaded and provided directly by Nature Publishing Group or their podcast platform partner. If you believe someone is using your copyrighted work without your permission, you can follow the process outlined here https://player.fm/legal.

Neonatal opioid withdrawal syndrome (NOWS) represents a major public health problem in the US with a high socioeconomic burden. The pathophysiology of this condition is not yet fully understood. Data from animal models have shown that opioids modulate brain reward signalling via an inflammatory cascade, however no such data exist for opioid-exposed neonates.


In this episode of Pediapod we meet Early Career Investigator Elizabeth Yen, an assistant professor of pediatrics at Tufts University School of Medicine. She recently published a pilot study which looked at the effects of prenatal opioid exposure on gene expression and white matter injury.


Read the full study here: Sex-specific inflammatory and white matter effects of prenatal opioid exposure: a pilot study | Pediatric Research (nature.com)



Hosted on Acast. See acast.com/privacy for more information.

  continue reading

113 episodes

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