Philip A. Thompson, MB, MS / William G. Wierda, MD, PhD - Achieving Innovation in CLL Care With BTK Inhibitors: Selection, Safety, and Sequencing Across the Disease Continuum


Manage episode 276913378 series 103624
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Go online to to view the activity, download slides and practice aids, and complete the post-test to earn credit. In this activity, an expert panel of hematologist-oncologists offers guidance on best practices for integrating Bruton’s tyrosine kinase (BTK) inhibitor options into chronic lymphocytic leukemia (CLL) treatment by presenting real-world clinical scenarios designed to illustrate cutting-edge treatment selection and sequencing strategies across the spectrum of CLL care, from treatment-naïve to relapsed disease. Upon completion of this activity, participants should be better able to: Discuss the implications of mechanistic and selectivity differences among first- and second-generation BTK inhibitors in the context of CLL care, Summarize updated clinical evidence and practice guideline recommendations for the use of BTK inhibitors in treatment-naïve and relapsed CLL, Select single-agent, sequential, or combination strategies using BTK inhibitors in treatment-naïve or relapsed CLL, or in patients unable to tolerate BTK inhibitor therapy, Develop a management plan to address unique adverse events associated with the use of BTK inhibitors in patients with CLL.

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