522: Generating Genomic Therapies to Treat Huntington's Disease and Other Conditions - Dr. Edward Rebar

People Behind the Science Podcast - Stories from Scientists about Science, Life, Research, and Science Careers

Dr. Edward Rebar is Senior Vice President and Chief Technology Officer at Sangamo Therapeutics. Ed and the team at Sangamo are developing genomic medicines. They use different techniques including gene therapy, ex vivo genome editing (using cells sourced from outside the body), in vivo genome editing (using a patient’s own cells within their body), and in vivo targeted gene regulation to downregulate their genes of interest. When Ed isn’t at work, he loves being outside with his wife, going to local parks, and visiting National Parks. When walking around observing nature, he tries to understand the story behind what he sees. He particularly enjoys exploring and pondering the amazing rock formations in Southern Utah. Ed earned his B.S. degree in biochemistry from Rutgers University and his Ph.D. in biophysics and structural biology from MIT. He conducted postdoctoral research at the University of California, Berkeley before joining the team at Sangamo in 1998. In our interview, Ed shares more about his life and research.