Cognitive Effects of Anticholinergics | GameChangers

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By Todd S. Eury. Discovered by Player FM and our community — copyright is owned by the publisher, not Player FM, and audio is streamed directly from their servers. Hit the Subscribe button to track updates in Player FM, or paste the feed URL into other podcast apps.

Many patients over age 65 take daily medications that have anticholinergic properties. We know the addition of these drugs can affect quality of life and cognition. In this episode, we talk with Dr. Kristin Meyer, an expert in geriatrics to explore the latest data and discuss what Pharmacists can do to promote the appropriate use of anticholinergics.
Additional Resources/References
Beers Criteria:

By the 2019 American Geriatrics Society Beers Criteria® Update Expert Panel. American Geriatrics Society 2019 Updated AGS Beers Criteria® for Potentially Inappropriate Medication Use in Older Adults. J Am Geriatr Soc. 2019;67(4):674-694. doi:10.1111/jgs.15767

Anticholinergic Risk Scale:
Rudolph JL, Salow MJ, Angelini MC, McGlinchey RE. The Anticholinergic Risk Scale and Anticholinergic Adverse Effects in Older Persons. Arch Intern Med. 2008;168(5):508–513. doi:10.1001/archinternmed.2007.106

Recent arge study associating anticholinergics with dementia:

Coupland CAC, Hill T, Dening T, Morriss R, Moore M, Hippisley-Cox J. Anticholinergic Drug Exposure and the Risk of Dementia: A Nested Case-Control Study. JAMA Intern Med. 2019;179(8):1084–1093. doi:10.1001/jamainternmed.2019.0677
This episode is accredited for CPE. For CE details and to claim credit click here: https://bit.ly/2UT97Ww

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