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Understanding the Effects of Extrachromosomal DNA on Cancer
Manage episode 420938073 series 2623015
Content provided by thescientistspeaks. All podcast content including episodes, graphics, and podcast descriptions are uploaded and provided directly by thescientistspeaks or their podcast platform partner. If you believe someone is using your copyrighted work without your permission, you can follow the process outlined here https://player.fm/legal.
In the 1960s, researchers in England noticed an anomaly when investigating chromosomes from surgically removed human tumors. Distinct from the intact chromosomes visible underneath the microscope were numerous “very small double chromatin bodies,” which are today better known as extrachromosomal DNA. Thanks to modern sequencing and imaging techniques, researchers now know that these tiny bits of circular DNA play a big role in cancer outcomes.
In this episode, Niki Spahich from The Scientist spoke with Lukas Chavez, an assistant professor in the Cancer Genome and Epigenetics Program at the Sanford Burnham Prebys Medical Discovery Institute, to learn more about his team’s multiomic exploration of extrachromosomal DNA and how it influences medulloblastoma progression and treatment.
Welcome to The Scientist Speaks, a podcast produced by The Scientist’s Creative Services Team. Our podcast is by scientists and for scientists. Once a month, we bring you the stories behind newsworthy molecular biology research.
This episode is brought to you by biomodal.
63 episodes
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Manage episode 420938073 series 2623015
Content provided by thescientistspeaks. All podcast content including episodes, graphics, and podcast descriptions are uploaded and provided directly by thescientistspeaks or their podcast platform partner. If you believe someone is using your copyrighted work without your permission, you can follow the process outlined here https://player.fm/legal.
In the 1960s, researchers in England noticed an anomaly when investigating chromosomes from surgically removed human tumors. Distinct from the intact chromosomes visible underneath the microscope were numerous “very small double chromatin bodies,” which are today better known as extrachromosomal DNA. Thanks to modern sequencing and imaging techniques, researchers now know that these tiny bits of circular DNA play a big role in cancer outcomes.
In this episode, Niki Spahich from The Scientist spoke with Lukas Chavez, an assistant professor in the Cancer Genome and Epigenetics Program at the Sanford Burnham Prebys Medical Discovery Institute, to learn more about his team’s multiomic exploration of extrachromosomal DNA and how it influences medulloblastoma progression and treatment.
Welcome to The Scientist Speaks, a podcast produced by The Scientist’s Creative Services Team. Our podcast is by scientists and for scientists. Once a month, we bring you the stories behind newsworthy molecular biology research.
This episode is brought to you by biomodal.
63 episodes
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Similar to The Scientist Speaks
Get in-depth coverage of current and future trends in technology, and how they are shaping business, entertainment, communications, science, politics, and society.
…
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Flash Forward is a show about possible (and not so possible) future scenarios. What would the warranty on a sex robot look like? How would diplomacy work if we couldn’t lie? Could there ever be a fecal transplant black market? (Complicated, it wouldn’t, and yes, respectively, in case you’re curious.) Hosted and produced by award winning science journalist Rose Eveleth, each episode combines audio drama and journalism to go deep on potential tomorrows, and uncovers what those futures might re ...
…
continue reading
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…
continue reading
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…
continue reading
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…
continue reading
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