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a16z Podcast

Andreessen Horowitz

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The a16z Podcast discusses tech and culture trends, news, and the future – especially as ‘software eats the world’. It features industry experts, business leaders, and other interesting thinkers and voices from around the world. This podcast is produced by Andreessen Horowitz (aka “a16z”), a Silicon Valley-based venture capital firm. Multiple episodes are released every week; visit a16z.com for more details and to sign up for our newsletters and other content as well!
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web3 with a16z crypto

a16z crypto, Sonal Chokshi, Chris Dixon

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"web3 with a16z" is a show about the next generation of the internet, and about how builders and users -- whether artists, coders, creators, developers, companies, organizations, or communities -- now have the ability to not just "read" (web1) + "write" (web2) but "own" (web3) pieces of the internet, unlocking a new wave of creativity and entrepreneurship. Brought to you by a16z crypto, this show is the definitive resource for understanding and going deeper on all things crypto and web3. Fro ...
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a16z Live

Andreessen Horowitz

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a16z Live is the place to listen to recorded live discussions and events featuring, hosted, or co-hosted by a16z partners (with outside voices too). As a reminder, all content posted here is provided for informational purposes only, and should not be relied upon as legal, business, investment, or tax advice. Views expressed are those of the individuals and not the views of Andreessen Horowitz, please see a16z.com/disclosures for more. To learn more about the broader a16z Podcast network and ...
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Raising Health

Andreessen Horowitz

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A myriad of AI, science, and technology experts explore the real challenges and enormous opportunities facing entrepreneurs who are building the future of health. Raising Health, a podcast by a16z Bio + Health and hosted by Kris Tatiossian and Olivia Webb, dives deep into the heart of biotechnology and healthcare innovation. Join veteran company builders, operators, and investors Vijay Pande, Julie Yoo, Vineeta Agarwala, and Jorge Conde, along with distinguished guests like Mark Cuban, Greg ...
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Most business podcasts follow a similar format: find a successful CEO and have them tell their story. This is not that show. Zero to IPO tackles real world problems with real world experience, featuring actionable advice and anecdotes from some of the world's most innovative founders. In season one, we broke down each stage of a company's growth cycle on a granular level with everyone from Parker Harris of Salesforce.com, to Julia Hartz of Eventbrite and Marc Andreessen of Andreessen Horowit ...
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16 Minutes on the News is a short news podcast where we cover the top headlines of the week, the a16z podcast way -- why are these topics in the news; what's real, what's hype from our vantage point; and what are our experts' quick takes on these trends? About the a16z Podcast: Discusses tech and culture trends, news, and the future -- especially as ‘software eats the world’. It features industry experts, business leaders, and other interesting thinkers and voices from around the world. This ...
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Across The Lines is a podcast that highlights the stories of Pan Asian American leaders and explores the intersection of their personal and professional journeys. Our vision is to inspire and empower the next generation of leaders through candid conversations about the confluence of identity and work.
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How to Start a Startup

Y Combinator and Stanford University: Sam Altman, Dustin Moskovitz, Paul Graham, Adora Cheung, Peter Thiel, Alex Schultz, Kevin Hale, Marc Andreessen, Ron Conway, Ben Silbermann, Alfred Lin, Patrick and John Collison, Aaron Levie, Reid Hoffman & more

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Sam Altman and the folks from Y Combinator offer up an amazing course in "How To Start A Startup" at Stanford. Course includes lectures from: Sam Altman, Dustin Moskovitz, Paul Graham, Adora Cheung, Peter Thiel, Alex Schultz, Kevin Hale, Marc Andreessen, Ron Conway, Ben Silbermann, Alfred Lin, Patrick and John Collison, Aaron Levie, Reid Hoffman, Keith Rabois, Ben Horowitz, Marissa Mayer, Hosian Rahman, Kirsty Nathoo, Carolynn Levy, and more
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Are we on the verge of a new American Dream? Welcome back to "The Ben & Marc Show," featuring a16z co-founders Marc Andreessen and Ben Horowitz. In this timely new episode, Marc and Ben explore the foundations of American life and identity. From the material aspects of home ownership, education, and healthcare, to the intangible aspects of communit…
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This was a big week in the world of AI, with both OpenAI and Google dropping significant updates. So big that we decided to break things down in a new format with our Consumer partners Bryan Kim and Justine Moore. We discuss the multi-modal companions that have found their voice, but also why not all audio is the same, and why several nuances like …
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Welcome back to "The Ben & Marc Show," featuring a16z co-founders Marc Andreessen and Ben Horowitz. In this new episode – the second in a 2 part series – Marc and Ben address a new round of questions regarding the "State of AI" in relation to company building. In light of recent developments at Boeing, Marc and Ben commence the episode with a discu…
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Make sure to check out our new AI + a16z feed: https://link.chtbl.com/aiplusa16z a16z General Partner Anjney Midha joins the podcast to discuss what's happening with hardware for artificial intelligence. Nvidia might have cornered the market on training workloads for now, but he believes there's a big opportunity at the inference layer — especially…
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Kim Branson, PhD, SVP and Global Head of AI and Machine Learning for GSK, joins Vijay Pande, founding partner at a16z Bio + Health. Together, they talk about how AI has improved drug discovery and development, as Kim walks through all the ways AI can be deployed in the lab. They also get into detail about what an ideal partner looks like and what k…
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with @jessepollak @NoahCitron @rhhackett Welcome to web3 with a16z, a show about building the next era of the internet by the team at a16z crypto, that includes me, host Robert Hackett. Today’s episode covers the bustling area of “layer 2” rollups, a technology for scaling “layer 1” blockchains such as Ethereum. Joining us is Jesse Pollak, who prev…
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In 2009 Discord cofounder and CEO, Jason Citron, started building tools and infrastructure for games. Fast forward to today and the platform has over 200 million monthly active users. In this episode, Jason, alongside a16z General Partner Anjney Midha—who merged his company Ubiquity6 with Discord in 2021—shares insights on the nuances of community-…
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Welcome back to "The Ben & Marc Show," featuring a16z co-founders Marc Andreessen and Ben Horowitz. In this new episode – the first of two parts – Marc and Ben answer YOUR questions on the “State of AI” as it relates to company building. In this one-on-one conversation, Ben and Marc discuss how small AI startups can compete with Big Tech’s massive …
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In this episode, Carl June, MD, pioneering immunologist and oncologist at the University of Pennsylvania, joins Jorge Conde, general partner at a16z Bio + Health. Together, they discuss Carl's work on CAR T, a remarkable story of the first use of CAR T in a pediatric patient, and Carl's take on where oncology treatments are headed next. Though this…
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Human nature fears the unknown, and with the rapid progress of AI, concerns naturally arise. Uncanny robocalls, data breaches, and misinformation floods are among the worries. But what about security in the era of large language models? In this episode, we hear from security leaders at OpenAI, Anthropic, and Google DeepMind. Matt Knight, Head of Se…
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"It turns out the spreadsheet is not actually the business, despite what you may have learned in business school." - Ben Horowitz Welcome back to "The Ben & Marc Show" featuring a16z co-founders Marc Andreessen and Ben Horowitz. In this second episode of a two-part series, Marc and Ben answer MORE questions about startup building in the post-COVID …
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In recent years, the AI landscape has seen huge advancements, from the release of Dall-E 2 in April 2022 to the emergence of AI music and video models in early 2024. While creative tools often steal the spotlight, AlphaFold 2 marked a groundbreaking AI breakthrough in biology in 2021. Since its release, this pioneering tool for predicting protein s…
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with @SuccinctJT @samrags_ @moodlezoup @rhhackett Welcome to web3 with a16z, a show about building the next era of the internet by the team at a16z crypto. That includes me, host Robert Hackett. Today's all new episode covers a very important and now fast developing area of technology that can help scale blockchains, but that also has many uses bey…
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Tom Hale, CEO of ŌURA, joins Vijay Pande, founding partner, and Daisy Wolf, investment partner at a16z Bio + Health. Together, they talk about the potential of wearables to change behavior, and how that can affect health. They also discuss how AI could maximize the usefulness of wearables and power the insights provided to wearers.…
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Over 3,700 companies applied to a16z’s SPEEDRUN. In this episode, we meet the founders pushing the boundaries of what games can be. From the fusion of traditional gaming elements with modern tech-twists, a16z General Partner Andrew Chen and Partner Josh Lu discuss the challenges and wins of creating games that are not only fun but also integrate se…
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Welcome to "The Ben & Marc Show" featuring a16z co-founders Marc Andreessen and Ben Horowitz. In this first episode of a two-part series, Marc and Ben visit the Twittersphere (or X-sphere) to answer YOUR questions about startup building in this post-COVID world. In this one-on-one conversation, Ben and Marc discuss the biggest tech disruptions of t…
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Philip Tagari, Chief Scientific Officer of insitro, joins Vijay Pande, founding general partner at a16z Bio + Health. Together, they discuss the transformative power of drugs in changing human health—and history. They also reflect on the evolution of the drug discovery process as it shifts from serendipitous discovery to AI-enabled engineering. Fin…
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Senator Todd Young (R-IN) speaks with a16z General Partner Martin Casado about the importance of open innovation and American leadership in AI, and why we need to support AI research at all levels — from the classroom to the war room. In this episode, we distinguish science fiction from science reality in the ever-evolving AI landscape. Resources: …
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The gaming industry stands as a pioneer of cutting-edge technologies, ushering in innovations like GPUs, virtual and augmented reality, physics engines, and immersive multiplayer experiences. In this episode, a16z cofounder Marc Andreessen and Andrew Chen, General Partner at a16z Games, dig into why a16z was compelled to establish a dedicated games…
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Vijay Pande, founding general partner of a16z Bio + Health, chats with the builders (and siblings) behind Devoted Health, Ed and Todd Park. The Park brothers, with decades of expertise in healthcare and policy, including as EVP and COO at athenahealth (Ed) and Chief Technology Officer of the United States (Todd), started Devoted with the idea of bu…
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with @creeefs @blauyourmind @rhhackett Welcome to web3 with a16z, a show about building the next generation of the internet from the team at a16z crypto — that includes me, Robert Hackett, your cohost and an editor here. Today's episode explores the merging of the physical and digital worlds, as well as what that means for the future of our interac…
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From air-defining radar and electronic systems that helped the Allies win World War II, the origins of Silicon Valley are deeply rooted in government and defense. In today's episode, we get the chance to revisit that relationship with the United States Deputy Secretary of Defense, Kathleen Hicks. Deputy Secretary Hicks has spent decades of her care…
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In this SaaS era, partnering with no one means competing with everyone. How the best companies take advantage of ecosystem-led growth—or where they sit in the SaaS ecosystem to improve acquisition, expansion, and access to new markets, as discussed by a16z general partner Sarah Wang and Crossbeam CEO Bob Moore. [00:01:43] The birth of ecosystem-led…
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Vijay Pande, founding general partner, and Julie Yoo, general partner at a16z Bio + Health, come together to talk through the grand challenges facing healthcare AI today. The discussion covers the implications of AI integration in healthcare workflows, AI as a potential catalyst for value-based care, and the potential for innovation in clinical tri…
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Does it matter that the Three Body Problem by Liu Cixin is a work of propaganda? I think it does. But it's going to take 2 hours to explain.Become a member of the Science Fiction community to continue the discussionWebsite - https://damiengwalter.comYouTube - https://www.youtube.com/c/DamienWalter/membershipPatreon - https://www.patreon.com/DamienW…
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“If America is going to be America in the next one hundred years, we have to get this right.” - Ben Horowitz This week on “The Ben & Marc Show”, a16z co-founders Ben Horowitz and Marc Andreessen take on one of the most hot button issues facing technology today: tech regulation and policy. In this one-on-one conversation, Ben and Marc delve into why…
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“If America is going to be America in the next one hundred years, we have to get this right.” - Ben Horowitz Welcome to “The Ben & Marc Show”, featuring a16z co-founders Ben Horowitz and Marc Andreessen. In this latest episode, Marc and Ben take on one of the most hot button issues facing technology today: tech regulation and policy. In this one-on…
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Greg Meyers, EVP and Chief Digital and Technology Officer at Bristol Myers Squibb (or BMS), joins a16z Bio + Health general partner Jorge Conde. Together, they talk about how AI could transform drug discovery and development at a large biopharma company—and how a company might have to adapt to harness AI; modalities they’re excited about; and Greg’…
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with @dennnnnnnnny @smc90 We know that technology has changed art, and that artists have evolved with every new technology — it’s a tale as old as humanity, moving from cave paintings to computers. Underlying these movements are endless debates around inventing versus remixing; between commercialism and art; between mainstream canon and fringe art;…
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From judging inventions on “Shark Tank” to reshaping the image of NBA ownership, Mark Cuban is known for many things. In this chat with a16z General Partner David Ulevitch, he discusses the importance of entrepreneurship for maintaining America’s status as the most innovative place on the planet. This includes making big bets, like he’s doing with …
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with @brian_armstrong @cdixon Welcome to web3 with a16z, a show about building the next generation of the internet from the team at a16z crypto. This episode features Brian Armstrong, CEO and cofounder of Coinbase, in conversation with a16z crypto founder and managing partner Chris Dixon. The conversation was originally recorded at our Founders Sum…
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with @tobi @bhorowitz Welcome to the web3 with a16z podcast. Today's episode features a conversation between Tobias Lütke, CEO and cofounder of the ecommerce platform Shopify, and Ben Horowitz, cofounder of a16z, which took place at our second annual Founders Summit in November. They discuss what it takes to build a breakout startup in a crowded ca…
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As any healthcare founder knows, it can be difficult to get into a room with the executives making purchase decisions for payors and providers—so we’re bringing the executives to you. This episode features interviews with payor and provider leaders about what they’re seeing and how they’re thinking about AI. Guided by Julie Yoo, general partner, an…
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At the a16z LP Summit, we brought hundreds of our limited partners and portfolio founders together in Las Vegas. The event was truly overflowing with stories of how founders are challenging the status quo and harnessing technology to make the world a better place. Amidst these stories, it became clear that in the realms of public safety and healthc…
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CEO of Quora Adam D’Angelo discusses how building infrastructure for creators can democratize AI, in conversation with a16z’s David George. [01:07] Social networks as compliment to AI [03:59] Poe: bringing AI to the masses [05:51] The future of AI is multi-model and multimodal [08:11] Is the model the product? [11:31] Building AI infrastructure for…
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Generative AI has initiated a transformative shift, reshaping our world in unprecedented ways. In a16z's AI Revolution series, we engage some of the most impactful builders in the field of AI discussing and debating where we are, where we’re going, and the big open questions in AI. In this episode, General Partner David George chats with Adam D'Ang…
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"There is a revolution unfolding in biotech. The confluence of new biological methods like CRISPR, virtually unlimited computational capacity, and machine learning has fundamentally transformed our ability to engineer biology for wide-ranging applications." Vijay Pande, founding general partner at a16z Bio + Health, joins the Software Engineering D…
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Nuclear energy accounts for 20% of the electricity in the United States, but remarkably, 2023 marked the commissioning of the U.S.'s first new nuclear reactor in over three decades. The past few years have been a story of changing public opinion, but equally, innovative startups crafting groundbreaking reactor designs and an ambitious announcement …
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Rosana Kapeller, CEO of Rome Therapeutics, and Marty Taylor, physician-scientist at Harvard Medical School, join Vineeta Agarwala, general partner, and Bryan Faust, investment partner at a16z Bio + Health. Together, they discuss Rosana and Marty's recent publication regarding a virus-like element in our genome known as LINE-1. LINE-1, part of our "…
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Artificial intelligence has taken the world by storm. But despite the hype around personalized avatars or podcast language translation, artificial intelligence is not only impacting the creative spheres; in fact it’s hard to find an industry that isn’t being touched by this technology – and defense of our country is far from excluded. In this episo…
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Dune is the Star Wars killer - https://youtu.be/JPOsoph3TCYBecome a member of the Science Fiction community to continue the discussionWebsite - https://damiengwalter.comYouTube - https://www.youtube.com/c/DamienWalter/membershipPatreon - https://www.patreon.com/DamienWalterSubscribe to the Science Fiction podcast feed for long-form commentaries on …
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The last few decades have been a period of transition for defense. An increasing number of startups have begun to rival large defense primes, the industry has gradually become a calculus of both hardware and software, and exponential technologies have forced the DoD to rethink how it has traditionally done business. These changing conditions were s…
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Vijay Pande, founding partner of a16z Bio + Health, dives deep with a16z Podcast host Steph Smith into the potential of DNA as a data storage mechanism. This episode, a cross-post with the a16z Podcast, draws parallels between Moore's Law and the race for "Moore's Law for DNA." Vijay discusses the density, longevity, and ubiquity of DNA, and how th…
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American Dynamism. A term coined by a16z General Partner, Katherine Boyle, two years ago, when she and David Ulevitch founded the firm's American Dynamism investing practice. Beyond a sector or movement, American Dynamism embodies innovation, community, and a unique philosophy touching every facet of American life. In this episode, we hear from 10 …
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with @cdixon @pmarca @bhorowitz @rhhackett Welcome to the web3 with a16z podcast. Today's episode is the final installment in our limited series on Read Write Own, the new book by a16z crypto founding partner Chris Dixon. Today's episode features Dixon in conversation with a16z cofounders Ben Horowitz and Marc Andreessen. Their discussion covers th…
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Welcome to “The Ben & Marc Show”, featuring a16z’s co-founders Ben Horowitz and Marc Andreessen. This week, Marc and Ben are joined by guest Chris Dixon to discuss his recent NY Times bestselling book “Read Write Own”, as well as the future of crypto, blockchain and Web3. Chris Dixon has been a General Partner at Andreessen Horowitz since 2012. He …
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Julie Klapstein, founding CEO of Availity, long-time healthcare executive, and a16z Bio + Health's newest advisory partner, joins Julie Yoo, general partner at a16z Bio + Health. Together, they delve into Julie Klapstein's rich career journey, which has spanned several decades of progress in healthcare. They also discussed building Availity, her ti…
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