The a16z Podcast discusses tech and culture trends, news, and the future – especially as ‘software eats the world’. It features industry experts, business leaders, and other interesting thinkers and voices from around the world. This podcast is produced by Andreessen Horowitz (aka “a16z”), a Silicon Valley-based venture capital firm. Multiple episodes are released every week; visit a16z.com for more details and to sign up for our newsletters and other content as well!
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Andreessen Horowitz ("a16z") co-founders Marc Andreessen and Ben Horowitz explore everything from science to business to culture, all through the lens of technology.
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"web3 with a16z" is a show about the next generation of the internet, and about how builders and users -- whether artists, coders, creators, developers, companies, organizations, or communities -- now have the ability to not just "read" (web1) + "write" (web2) but "own" (web3) pieces of the internet, unlocking a new wave of creativity and entrepreneurship. Brought to you by a16z crypto, this show is the definitive resource for understanding and going deeper on all things crypto and web3. Fro ...
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a16z Live is the place to listen to recorded live discussions and events featuring, hosted, or co-hosted by a16z partners (with outside voices too). As a reminder, all content posted here is provided for informational purposes only, and should not be relied upon as legal, business, investment, or tax advice. Views expressed are those of the individuals and not the views of Andreessen Horowitz, please see a16z.com/disclosures for more. To learn more about the broader a16z Podcast network and ...
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A myriad of AI, science, and technology experts explore the real challenges and enormous opportunities facing entrepreneurs who are building the future of health. Raising Health, a podcast by a16z Bio + Health and hosted by Kris Tatiossian and Olivia Webb, dives deep into the heart of biotechnology and healthcare innovation. Join veteran company builders, operators, and investors Vijay Pande, Julie Yoo, Vineeta Agarwala, and Jorge Conde, along with distinguished guests like Mark Cuban, Greg ...
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Most business podcasts follow a similar format: find a successful CEO and have them tell their story. This is not that show. Zero to IPO tackles real world problems with real world experience, featuring actionable advice and anecdotes from some of the world's most innovative founders. In season one, we broke down each stage of a company's growth cycle on a granular level with everyone from Parker Harris of Salesforce.com, to Julia Hartz of Eventbrite and Marc Andreessen of Andreessen Horowit ...
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Join writer and storyteller Damien Walter on an exploration of the world as seen through a science fiction lens.
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16 Minutes on the News is a short news podcast where we cover the top headlines of the week, the a16z podcast way -- why are these topics in the news; what's real, what's hype from our vantage point; and what are our experts' quick takes on these trends? About the a16z Podcast: Discusses tech and culture trends, news, and the future -- especially as ‘software eats the world’. It features industry experts, business leaders, and other interesting thinkers and voices from around the world. This ...
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Finance & Culture aims to elevate listener's financial literacy by informing, inspiring, and empowering them to prosper, thus yielding long-term success.
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Across The Lines is a podcast that highlights the stories of Pan Asian American leaders and explores the intersection of their personal and professional journeys. Our vision is to inspire and empower the next generation of leaders through candid conversations about the confluence of identity and work.
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1
How to Start a Startup
Y Combinator and Stanford University: Sam Altman, Dustin Moskovitz, Paul Graham, Adora Cheung, Peter Thiel, Alex Schultz, Kevin Hale, Marc Andreessen, Ron Conway, Ben Silbermann, Alfred Lin, Patrick and John Collison, Aaron Levie, Reid Hoffman & more
Sam Altman and the folks from Y Combinator offer up an amazing course in "How To Start A Startup" at Stanford. Course includes lectures from: Sam Altman, Dustin Moskovitz, Paul Graham, Adora Cheung, Peter Thiel, Alex Schultz, Kevin Hale, Marc Andreessen, Ron Conway, Ben Silbermann, Alfred Lin, Patrick and John Collison, Aaron Levie, Reid Hoffman, Keith Rabois, Ben Horowitz, Marissa Mayer, Hosian Rahman, Kirsty Nathoo, Carolynn Levy, and more
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Marc Andreessen on Building Netscape & the Birth of the Browser
1:44:56
1:44:56
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Welcome back to "The Ben & Marc Show," featuring a16z co-founders Marc Andreessen and Ben Horowitz. In this special episode, Marc and Ben dive deep into the REAL story behind the creation of Netscape—a web browser co-created by Marc that revolutionized the internet and changed the world. As Ben notes at the top, until today, this story has never be…
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Cybersecurity's Past, Present, and AI-Driven Future
43:43
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Is it time to hand over cybersecurity to machines amidst the exponential rise in cyber threats and breaches? We trace the evolution of cybersecurity from minimal measures in 1995 to today's overwhelmed DevSecOps. Travis McPeak, CEO and Co-founder of Resourcely, kicks off our discussion by discussing the historical shifts in the industry. Kevin Tian…
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On Finding Product Market Fit — and Meaning
1:05:51
1:05:51
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with @jasonrosenthal @benrbn Welcome to web3 with a16z, a show about building the next generation of the internet. Our featured guest today is serial entrepreneur Ben Rubin, who previously built the viral livestreaming app Meerkat, and then the group video chat app Houseparty — acquired by Epic Games in 2019 — and who is now CEO and cofounder of He…
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Regulation as a Catalyst with Jonathan Bush and Chris Severn
37:08
37:08
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Jonathan Bush, founder and CEO of Zus Health, and Chris Severn, cofounder and CEO of Turquoise Health, join Julie Yoo, general partner, and Colin Rom, head of public policy for a16z Bio + Health. We’ve long believed that regulatory change can be a catalyst for company creation. In this episode, Jonathan and Chris detail how that was true for them. …
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In the Vault: New Applications in Fintech with Plaid’s Zach Perret and Marqeta’s Simon Khalaf
24:43
24:43
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In this conversation, which took place at a16z's Connect Fintech event, a16z General Partner Angela Strange, Plaid CEO and cofounder Zach Perret, and Marqeta CEO Simon Khalaf discuss how AI will shape the future of banking, the battle between payment rails in the U. S., and how there's still opportunity to transform the basic credit card into a ful…
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Brooke Boyarsky Pratt, founder and CEO of knownwell, joins Vineeta Agarwala, general partner at a16z Bio + Health. Together, they talk about the value of obesity medicine practitioners, patient-centric medical homes, and how Brooke believes the metabolic health space will evolve over time. This is the second episode in Raising Health’s series on th…
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The Transformative Power of AI in Science with Pushmeet Kohli
56:25
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In this episode, originally recorded for the a16z Podcast, host Steph Smith interviews Pushmeet Kohli, DeepMind's VP of Research focused on AI for science. They are joined by a16z Bio + Health founding partner Vijay Pande. Together, they discuss AI at scale, and its power to transform science.By Vijay Pande, Olivia Webb, Kris Tatiossian, Steph Smith, Pushmeet Kohli
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Governing democracy, the internet, and boardrooms
1:35:40
1:35:40
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with @NoahRFeldman, @ahall_research, @rhhackett Welcome to web3 with a16z. I'm Robert Hackett and today we have a special episode about governance in many forms — from nation states to corporate boards to internet services and beyond. Our special guests are Noah Feldman, constitutional law scholar at Harvard who also architected the Meta oversight …
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In this latest episode on the State of AI, Ben and Marc discuss how small AI startups can compete with Big Tech’s massive compute and data scale advantages, reveal why data is overrated as a sellable asset, and unpack all the ways the AI boom compares to the internet boom. Subscribe to the Ben & Marc podcast: https://link.chtbl.com/benandmarc Stay …
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The Science and Supply of GLP-1s with Chronis Manolis
31:30
31:30
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Chronis Manolis, SVP and Chief Pharmacy Officer of UPMC Health Plan, joins Julie Yoo, general partner, Daisy Wolf, investment partner, and Will Shrank, venture partner, of a16z Bio + Health. Together, they discuss how payors and providers are thinking about anti-obesity medications, as well as pricing and prior authorization considerations. This is…
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Predicting Revenue in Usage-based Pricing
38:16
38:16
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Over the past decade, usage-based pricing has soared in popularity. Why? Because it aligns cost with value, letting customers pay only for what they use. But, that flexibility is not without issues - especially when it comes to predicting revenue. Fortunately, with the right process and infrastructure, your usage-based revenue can become more predi…
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California's Senate Bill 1047: What You Need to Know
31:52
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On May 21, the California Senate passed bill 1047. This bill – which sets out to regulate AI at the model level – wasn’t garnering much attention, until it slid through an overwhelming bipartisan vote of 32 to 1 and is now queued for an assembly vote in August that would cement it into law. In this episode, a16z General Partner Anjney Midha and Ven…
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The Science and Supply of GLP-1s with Brooke Boyarsky Pratt
42:53
42:53
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Brooke Boyarsky Pratt, founder and CEO of knownwell, joins Vineeta Agarwala, general partner at a16z Bio + Health. Together, they talk about the value of obesity medicine practitioners, patient-centric medical homes, and how Brooke believes the metabolic health space will evolve over time. This is the second episode in our series on the science and…
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with @jasonrosenthal @skominers @meigga @rhhackett Welcome to web3 with a16z, I’m Robert Hackett and today, we discuss pricing strategy for startups — from traditional businesses to web2 to web3. Topics we cover include: unit economics understanding consumer psychology using onchain data to inform pricing decisions Common mistakes and how to avoid …
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The Science and Supply of GLP-1s with Carolyn Jasik
29:42
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Carolyn Jasik, MD, Chief Medical Officer of Omada Health, joins Vijay Pande, founding partner of a16z Bio + Health. As Ozempic, Wegovy, Mounjaro, and Zepbound capture the healthcare spotlight, we’ve developed a series of episodes that go beyond the headlines and take you into conversations with the specialists. Our first guest is Carolyn Jasik, Chi…
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Consumer AI is moving fast, so who's leading the charge? a16z Consumer Partners Olivia Moore and Bryan Kim discuss our GenAI 100 list and what it takes for an AI model to stand out and dominate the market. They discuss how these cutting-edge apps are connecting with their users and debate whether traditional strategies like paid acquisition and net…
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Open Sourcing the Superchain (with Optimism)
1:25:59
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with @jinglejamOP @eddylazzarin @rhhackett Hello and welcome to web3 with a16z, a show about building the next era of the internet by the team at a16z crypto, that includes me, host Robert Hackett. Today’s episode features Jing Wang, CEO and executive director of the Optimism Foundation, along with a16z crypto CTO Eddy Lazzarin. We discuss the pecu…
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Finding a Single Source of AI Truth With Marty Chavez From Sixth Street
35:51
35:51
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a16z General Partner David Haber talks with Marty Chavez, vice chairman and partner at Sixth Street Partners, about the foundational role he’s had in merging technology and finance throughout his career, and the magical promises and regulatory pitfalls of AI. This episode is taken from “In the Vault”, a new audio podcast series by the a16z Fintech …
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The Intersection of Biotech x High Tech with Vineeta Agarwala
57:09
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Vineeta Agarwala, MD, PhD, joins Luke Timmerman's The Long Run podcast on stage at the Life Science Innovation Northwest Conference. They discuss everything from AI for drug discovery to Vineeta's ongoing clinical work as a physician and how that influences her perspective.By Luke Timmerman, Kris Tatiossian, Vineeta Agarwala, Olivia Webb
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Are we on the verge of a new American Dream? Welcome back to "The Ben & Marc Show," featuring a16z co-founders Marc Andreessen and Ben Horowitz. In this timely new episode, Marc and Ben explore the foundations of American life and identity. From the material aspects of home ownership, education, and healthcare, to the intangible aspects of communit…
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A Big Week in AI: GPT-4o & Gemini Find Their Voice
23:54
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This was a big week in the world of AI, with both OpenAI and Google dropping significant updates. So big that we decided to break things down in a new format with our Consumer partners Bryan Kim and Justine Moore. We discuss the multi-modal companions that have found their voice, but also why not all audio is the same, and why several nuances like …
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AI, Robotics & the Future of Manufacturing
1:15:12
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Welcome back to "The Ben & Marc Show," featuring a16z co-founders Marc Andreessen and Ben Horowitz. In this new episode – the second in a 2 part series – Marc and Ben address a new round of questions regarding the "State of AI" in relation to company building. In light of recent developments at Boeing, Marc and Ben commence the episode with a discu…
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Make sure to check out our new AI + a16z feed: https://link.chtbl.com/aiplusa16z a16z General Partner Anjney Midha joins the podcast to discuss what's happening with hardware for artificial intelligence. Nvidia might have cornered the market on training workloads for now, but he believes there's a big opportunity at the inference layer — especially…
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AI in Pharmaceutical R&D with Kim Branson
31:15
31:15
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Kim Branson, PhD, SVP and Global Head of AI and Machine Learning for GSK, joins Vijay Pande, founding partner at a16z Bio + Health. Together, they talk about how AI has improved drug discovery and development, as Kim walks through all the ways AI can be deployed in the lab. They also get into detail about what an ideal partner looks like and what k…
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Layer 2, Rollups, and Building Onchain (with Base)
1:02:33
1:02:33
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with @jessepollak @NoahCitron @rhhackett Welcome to web3 with a16z, a show about building the next era of the internet by the team at a16z crypto, that includes me, host Robert Hackett. Today’s episode covers the bustling area of “layer 2” rollups, a technology for scaling “layer 1” blockchains such as Ethereum. Joining us is Jesse Pollak, who prev…
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How Discord Became a Developer Platform
42:24
42:24
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In 2009 Discord cofounder and CEO, Jason Citron, started building tools and infrastructure for games. Fast forward to today and the platform has over 200 million monthly active users. In this episode, Jason, alongside a16z General Partner Anjney Midha—who merged his company Ubiquity6 with Discord in 2021—shares insights on the nuances of community-…
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Welcome back to "The Ben & Marc Show," featuring a16z co-founders Marc Andreessen and Ben Horowitz. In this new episode – the first of two parts – Marc and Ben answer YOUR questions on the “State of AI” as it relates to company building. In this one-on-one conversation, Ben and Marc discuss how small AI startups can compete with Big Tech’s massive …
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In this episode, Carl June, MD, pioneering immunologist and oncologist at the University of Pennsylvania, joins Jorge Conde, general partner at a16z Bio + Health. Together, they discuss Carl's work on CAR T, a remarkable story of the first use of CAR T in a pediatric patient, and Carl's take on where oncology treatments are headed next. Though this…
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Securing the Black Box: OpenAI, Anthropic, and GDM Discuss
59:59
59:59
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Human nature fears the unknown, and with the rapid progress of AI, concerns naturally arise. Uncanny robocalls, data breaches, and misinformation floods are among the worries. But what about security in the era of large language models? In this episode, we hear from security leaders at OpenAI, Anthropic, and Google DeepMind. Matt Knight, Head of Se…
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Startup Building: Challenges & Opportunities
1:15:47
1:15:47
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"It turns out the spreadsheet is not actually the business, despite what you may have learned in business school." - Ben Horowitz Welcome back to "The Ben & Marc Show" featuring a16z co-founders Marc Andreessen and Ben Horowitz. In this second episode of a two-part series, Marc and Ben answer MORE questions about startup building in the post-COVID …
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Can AI Advance Science? DeepMind's VP of Science Weighs In
55:48
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In recent years, the AI landscape has seen huge advancements, from the release of Dall-E 2 in April 2022 to the emergence of AI music and video models in early 2024. While creative tools often steal the spotlight, AlphaFold 2 marked a groundbreaking AI breakthrough in biology in 2021. Since its release, this pioneering tool for predicting protein s…
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Theory to Code: Building the Breakthrough zkVM Jolt
1:15:09
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with @SuccinctJT @samrags_ @moodlezoup @rhhackett Welcome to web3 with a16z, a show about building the next era of the internet by the team at a16z crypto. That includes me, host Robert Hackett. Today's all new episode covers a very important and now fast developing area of technology that can help scale blockchains, but that also has many uses bey…
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In the Vault: Finding a Single Source of AI Truth With Marty Chavez From Sixth Street
37:00
37:00
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37:00
In a new episode of In the Vault, a16z General Partner David Haber talks with Marty Chavez, a partner and vice chairman of Sixth Street Partners, about the foundational role he’s had in merging technology and finance throughout his career, and the magical promises and regulatory pitfalls of AI. 0-1:30 Intro 1:30-12:50 Marty's history and transition…
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In the Vault: Placing Multiple Bets on a ‘Mosaic of Solutions’ With Former Global Payments CEO Jeff Sloan
32:14
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In a new episode of In the Vault, a16z General Partner Angela Strange talks with Jeff Sloan, former CEO of Global Payments, about how he was early to spot significant industry trends, how to make bets that move an organization, and the sea change that AI represents for the financial services industry. 0-1:40 Intro 1:40-8:15 Joining Global Payments …
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Longevity as a Health Asset with Tom Hale
27:54
27:54
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Tom Hale, CEO of ŌURA, joins Vijay Pande, founding partner, and Daisy Wolf, investment partner at a16z Bio + Health. Together, they talk about the potential of wearables to change behavior, and how that can affect health. They also discuss how AI could maximize the usefulness of wearables and power the insights provided to wearers.…
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In the Vault: Turning Developers Into Clients With Marco Argenti From Goldman Sachs
29:31
29:31
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In a new episode of In the Vault, a16z General Partner David Haber talks with Marco Argenti, the chief information officer at Goldman Sachs, about bringing fintech processes into financial services, turning developers into clients, and how AI is a major inflection point in the history of technology. 0-1:30 Intro 1:30-12:05 From tech to financial se…
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Next-Gen Gaming: AI Souls, Real-time Culture, Personalized Avatars
30:36
30:36
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Over 3,700 companies applied to a16z’s SPEEDRUN. In this episode, we meet the founders pushing the boundaries of what games can be. From the fusion of traditional gaming elements with modern tech-twists, a16z General Partner Andrew Chen and Partner Josh Lu discuss the challenges and wins of creating games that are not only fun but also integrate se…
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Building Startups: Major Shifts in Tech & Culture
1:13:59
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Welcome to "The Ben & Marc Show" featuring a16z co-founders Marc Andreessen and Ben Horowitz. In this first episode of a two-part series, Marc and Ben visit the Twittersphere (or X-sphere) to answer YOUR questions about startup building in this post-COVID world. In this one-on-one conversation, Ben and Marc discuss the biggest tech disruptions of t…
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The Power of Drug Discovery with Philip Tagari
31:36
31:36
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Philip Tagari, Chief Scientific Officer of insitro, joins Vijay Pande, founding general partner at a16z Bio + Health. Together, they discuss the transformative power of drugs in changing human health—and history. They also reflect on the evolution of the drug discovery process as it shifts from serendipitous discovery to AI-enabled engineering. Fin…
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Why America Must Lead in AI Investment with Senator Young (R-IN)
24:55
24:55
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Senator Todd Young (R-IN) speaks with a16z General Partner Martin Casado about the importance of open innovation and American leadership in AI, and why we need to support AI research at all levels — from the classroom to the war room. In this episode, we distinguish science fiction from science reality in the ever-evolving AI landscape. Resources: …
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Game On: Marc Andreessen & Andrew Chen Talk Creative Computers
40:39
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The gaming industry stands as a pioneer of cutting-edge technologies, ushering in innovations like GPUs, virtual and augmented reality, physics engines, and immersive multiplayer experiences. In this episode, a16z cofounder Marc Andreessen and Andrew Chen, General Partner at a16z Games, dig into why a16z was compelled to establish a dedicated games…
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AI-Enabled Continuity of Care with Ed and Todd Park
25:41
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Vijay Pande, founding general partner of a16z Bio + Health, chats with the builders (and siblings) behind Devoted Health, Ed and Todd Park. The Park brothers, with decades of expertise in healthcare and policy, including as EVP and COO at athenahealth (Ed) and Chief Technology Officer of the United States (Todd), started Devoted with the idea of bu…
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Let's Get Digi-Physical: From 'Tap' Chips to Taylor Swift
1:16:43
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with @creeefs @blauyourmind @rhhackett Welcome to web3 with a16z, a show about building the next generation of the internet from the team at a16z crypto — that includes me, Robert Hackett, your cohost and an editor here. Today's episode explores the merging of the physical and digital worlds, as well as what that means for the future of our interac…
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Inside the Department of Defense and its Vision for the Future
30:19
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From air-defining radar and electronic systems that helped the Allies win World War II, the origins of Silicon Valley are deeply rooted in government and defense. In today's episode, we get the chance to revisit that relationship with the United States Deputy Secretary of Defense, Kathleen Hicks. Deputy Secretary Hicks has spent decades of her care…
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Harnessing Ecosystem-Led Growth with Bob Moore of Crossbeam
34:32
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In this SaaS era, partnering with no one means competing with everyone. How the best companies take advantage of ecosystem-led growth—or where they sit in the SaaS ecosystem to improve acquisition, expansion, and access to new markets, as discussed by a16z general partner Sarah Wang and Crossbeam CEO Bob Moore. [00:01:43] The birth of ecosystem-led…
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Grand Challenges in Healthcare AI with Vijay Pande and Julie Yoo
38:33
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Vijay Pande, founding general partner, and Julie Yoo, general partner at a16z Bio + Health, come together to talk through the grand challenges facing healthcare AI today. The discussion covers the implications of AI integration in healthcare workflows, AI as a potential catalyst for value-based care, and the potential for innovation in clinical tri…
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Does it matter that the Three Body Problem by Liu Cixin is a work of propaganda? I think it does. But it's going to take 2 hours to explain.Become a member of the Science Fiction community to continue the discussionWebsite - https://damiengwalter.comYouTube - https://www.youtube.com/c/DamienWalter/membershipPatreon - https://www.patreon.com/DamienW…
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Politics & the Future of Tech with Marc Andreessen and Ben Horowitz
1:43:09
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“If America is going to be America in the next one hundred years, we have to get this right.” - Ben Horowitz This week on “The Ben & Marc Show”, a16z co-founders Ben Horowitz and Marc Andreessen take on one of the most hot button issues facing technology today: tech regulation and policy. In this one-on-one conversation, Ben and Marc delve into why…
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“If America is going to be America in the next one hundred years, we have to get this right.” - Ben Horowitz Welcome to “The Ben & Marc Show”, featuring a16z co-founders Ben Horowitz and Marc Andreessen. In this latest episode, Marc and Ben take on one of the most hot button issues facing technology today: tech regulation and policy. In this one-on…
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Adapting Biopharma to AI with Greg Meyers
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33:30
Greg Meyers, EVP and Chief Digital and Technology Officer at Bristol Myers Squibb (or BMS), joins a16z Bio + Health general partner Jorge Conde. Together, they talk about how AI could transform drug discovery and development at a large biopharma company—and how a company might have to adapt to harness AI; modalities they’re excited about; and Greg’…
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