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Welcome to BIOTECH NATION !!! With understandable interviews requiring no background in science, BTN attracts a wide global audience. From everyday people looking for hope in treatments in development, to bioentrepreneurs interested in the experience of their fellow travelers, to venture capitalists looking for possibilities in cutting-edge breakthroughs, to scientists simply interested in the work of others, BioTech Nation is the voice of human endeavor, driving science to new realities for ...
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CRAFTED. is a show about great products and the people who make them. Incredible founders, makers, and innovators reveal how they build game-changing products and companies — and how you can, too. Honored twice by the Webby Awards as a top tech podcast. Discover the future of product development, technology, and AI on CRAFTED. Hosted by Dan Blumberg, an entrepreneur, product leader, and former public radio host. Each episode of CRAFTED. brings you closer to the founders, innovators, and tech ...
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Amadeus and Friends

Amadeus Capital Partners

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Amadeus Capital Partners has been a trailblazer for three decades, investing in people who create transformational technologies and sustainable businesses. We’ve backed nearly 200 startups and scaleups across Europe and, more recently, in Latin America. In Amadeus and Friends, you’ll hear from some of the world’s greatest innovators in quantum computing, AI, biotech and more, sharing their commercial journeys, the highs and the lows, and how they’ve approached commercialisation with the supp ...
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This week on BioTech Nation, Dr. Sam Clark, CEO of Terran Biosciences, discusses prodrugs—modified drugs that improve absorption and efficacy. Also, Terran Biosciences is developing non-hallucinogenic psychedelics by blocking the serotonin 2A receptor and manufacturing psychedelics like LSD and psilocybin for research. Dr. Clark highlights Terran's…
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Colin Nederkoorn is the founder and CEO of Customer.io, a top customer engagement platform that enables companies to send the right message to the right user at the right time on the right channel. The platform is used by Notion and lots of other top SaaS companies to personalize user onboarding and more. When Customer.io was founded in 2011, there…
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This week on Biotech Nation, Dr. Marianne De Backer, CEO of Vir Biotechnology talks about their Phase 2 clinical trials targeting hepatitis B and D co-infections. Vir's approach uses two drugs: tobevibart (an antibody) and elebsiran (an siRNA). These drugs prevent the virus from entering liver cells and stop it from replicating. Preliminary results…
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DevPost powers most of the world’s hackathons. And, according to founder and CEO Brandon Kessler, lately there is one overarching directive: “Executives from the top down are saying: `We need to do hackathons to uncover the value of ai.`” Nearly every one of the 1,200 hackathons DevPost powered last year was AI-centric. On this episode of CRAFTED.,…
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This week on Biotech Nation, Dr. Neil Kumar, founder and CEO of BridgeBio Pharma. Dr. Kumar emphasizes that genetic diseases, particularly Mendelian diseases caused by single gene mutations, are solvable due to advancements in genetic measurement and understanding. He discusses BridgeBio Pharma's innovative corporate structure, which consists of mu…
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Wonder aims to be a “super app for mealtime”, with people turning to it for everything from delivery to groceries to meal kits and more... It’s a very ambitious food-tech startup founded by Marc Lore, the legendary founder who previously built, scaled, and sold Diapers.com and Jet.com (to Amazon and Walmart, respectively). Wonder is rapidly opening…
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What’s next after Ozempic and Wegovy and the like? How about a drug in development which releases all the relevant hormones, and not just GLP-1. And doesn’t require injecting. Dr. Steffen-Sebastian Bolz from Aphaia (ah-phi-ah) Pharma explains their approach, currently in Phase 2.By Moira Gunn
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This week on BioTech Nation, Dr. Sam Blackman, Founder and Head of Research and Development from Day One Biopharmaceuticals, shares the story behind the FDA approval of a groundbreaking drug for the most common childhood brain cancer. He talks about their innovative approach to starting a biopharma company and how it led to a newly FDA approved dru…
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When Docker restructured, the company went back to its roots: super-serving developers. CTO Justin Cormack says that’s why the company is developer-obsessed, not customer-obsessed: “We really wanted to focus on the fact that it's the developer who loves Docker. It's the developer who is going to be using Docker every day…” Over the past decade, Doc…
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This week we have a best of rerun with Dr. Mark Sumeray from Amolyt Pharma. Dr. Sumeray talks about their innovative approach to treating hormonal conditions. We’ll talk about two – when your parathyroid has been injured or removed, often during thyroid surgery, and another – when the pituitary starts overproducing growth hormone.…
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Software, hardware, and biotechnology are playing an increasingly transformative role in our mental health and wellness. On this episode of CRAFTED., recorded live on the “Next” stage at SXSW, we discuss what investors look for in these new companies and how they separate what’s real — and what’s near-term — from what’s hype. On stage with host Dan…
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This week Dr. Daniel Kraft, Tech Nation Health Chief Correspondent, discusses advanced health tech. Dr. Kraft highlights his use of wearables like the Apple Watch, Oura ring, and non-invasive blood pressure monitors. He also introduces "otherables," which track health without being worn, using devices like cameras and modified WiFi. These technolog…
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Dr. Gabriella Rosen Kellerman is the Chief Product and Innovation Officer at BetterUp, a multi-billion dollar startup that helps people and companies level up. Through a combination of human coaching and AI, BetterUp is able to offer the kind of executive coaching that used to be reserved for... executives. On this episode of CRAFTED. we dig into h…
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Diaa El All is the founder and CEO of Soundful, which enables anyone to create brand new music in just a few seconds with AI. And on this episode of CRAFTED., we are literally making music. We’re also talking about the ethics of using AI to make music. Diaa has been very outspoken about what he sees as the misguided practices of other AI+music comp…
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This week on BioTech Nation, Dr. Moira Gunn and Dr. Daniel Kraft discuss how robotics, AI, and virtual reality are transforming surgery. These technologies make procedures less invasive and improve training and outcomes worldwide. Future advancements may include tiny robots performing internal procedures. Security is crucial to prevent hacking of m…
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Paige Costello is the the head of AI and co-head of product at Asana and on this episode of CRAFTED. we're exploring what it means to ship products with AI, how AI will change the way work gets done, and how to organize your teams for success in this brave new world. We explore: How the future of work – and communicating about work – is changing Wh…
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Dr. John Scarlett, President and CEO of Geron Corporation talks about their drug Imetelstat for myelodysplastic syndrome (MDS). MDS patients often require frequent blood transfusions, impacting their quality of life. Imetelstat, a telomerase inhibitor, aims to reduce transfusion dependence by targeting cancer cells in the bone marrow. Phase three t…
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Dr. Daniel Kraft, Tech Nation Health Chief Correspondent discusses the gap between medical innovation and its adoption into standard practice. He highlights that it typically takes 17 years for a medical discovery to become common practice, but big data and AI could accelerate this. He emphasizes the importance of sharing medical data and initiativ…
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This week, Dr. Steve Quake from the Chan Zuckerberg Initiative about their goal to tackle all human diseases in the next century. We discuss CZI's innovative approach, including building Biohubs and funding collaborative research. Dr. Quake explains the importance of something called The Virtual Cell project, aiming to use AI to model every human c…
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This week on Biotech Nation, I speak with Dr. Neal Kassell about focused ultrasound technology. We discuss its noninvasive approach, its diverse applications in treating various medical conditions, and its potential to revolutionize treatments for diseases like Alzheimer's, Parkinson's, and cancer. Dr. Kassell also shares insights into ongoing clin…
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This week on BioTech Nation, we explore new efforts in treating cancer with Dr. Sean Bohen, President and CEO of Olema Oncology. We discuss progress in treating breast cancer, particularly ER+/HER2- breast cancer, which accounts for 70% of diagnoses this year. They examine the biology behind these cancers and how Olema's lead compound, palazestrant…
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This week - Dr. Sanjay Shukla, CEO of Atyr Pharma, discusses the revolutionary potential of mRNA technology in creating new medicines. They explore Atyr's pioneering approach to leveraging tRNA fragments for treating pulmonary sarcoidosis and other organ-specific conditions, aiming to improve patient outcomes while minimizing reliance on convention…
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“So if you take any great startup and look backwards, you'll see that 90 percent of their growth came from like 10 percent of the stuff that they tried. So how do you find that 10 percent as quickly as possible?” Matt Lerner has advised hundreds of startups on how to grow. Now, the CEO of SYSTM has written a book called Growth Levers and How to Fin…
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Amadeus Capital Partners CEO Anne Glover sits down with Catherine La Torre, Independent NED and former CEO of British Patient Capital, to delve into the dynamics of the UK venture capital industry. Catherine shares invaluable insights gleaned from her illustrious career journey, highlighting the remarkable achievements of British Patient Capital in…
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Dr. Peter DeMuth, Chief Scientific Officer of Elicio Therapeutics, discusses the revolutionary approach of detecting cancer at its earliest stages through circulating tumor DNA (ctDNA) tests. Highlighting their innovative treatment method, which aims to train the body's immune cells to recognize and destroy cancer cells, the episode explores the po…
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In this week's episode, Dr. Moira Gunn interviews Dr. Chris Pirie from HDT Bio about their novel approach to cancer prevention through vaccines. They discuss leveraging mRNA technology to target specific tumor mutations and prime the immune system to recognize and eliminate cancer cells. Dr. Pirie highlights ongoing efforts to develop vaccines for …
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On April 1st, 2013, ProdPad promised something revolutionary: “We now take your backlog of ideas, and with highly advanced big data crunching algorithm technology, automagically render a complete and accurate product roadmap. [...] The Auto-Roadmap Tool not only builds itself, but also covers for the hardest part of the Product Manager’s job: Getti…
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Enjoy this bonus, happy hour edition of CRAFTED., recorded live during SXSW. It’s a very unCRAFTED. CRAFTED. Featuring four innovators on a rooftop in Austin talking about what struck them at this year’s SXSW. Kick back and unwind with Christie Nicholson (Founder of the Studio for Communicating Complexity), Kwaku Aning (Director, Center for Innovat…
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This week I speak with Dr. Robert Ang from Vor Biopharma about their innovative approach to treating acute myeloid leukemia (AML). AML is a type of blood cancer that affects the bone marrow, leading to the overgrowth of cancerous cells. Dr. Ang explains that traditional treatments, such as chemotherapy and stem cell transplants, have limitations an…
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In this week's episode of BioTech Nation, Dr. David Bearss, President and CEO of Halia Therapeutics, discusses inflammation and its reduction over a lifetime and in response to various incidents. He unveils the inflammasome, a recently discovered protein complex critical in regulating inflammatory responses and its potential in treating chronic dis…
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Manjari Chandran-Ramesh, Partner on our Early Stage investing team embarks on an insightful journey into the cutting-edge realm of quantum computing with industry pioneers Professor Stephanie Simmons from Photonic Inc and Hermann Hauser, co-founder of Amadeus and Board Director of Photonic. The conversation delves into the challenges and opportunit…
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Career trajectories used to be like steamships: full steam ahead. And then they became more like sailboats: lots of tacking. But now… we’re swirling in whitewater. And, as the Chief Product and Innovation Officer at BetterUp, Dr. Gabriella Rosen Kellerman helps people build the skill they need to flourish: “When you're kayaking in the whitewater. I…
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Tech Nation Health, Chief Correspondent Dr. Daniel Kraft discusses the concept of "food as medicine." Dr. Kraft emphasizes the evolving understanding of nutrition and its profound impact on health, advocating for a shift towards personalized nutrition using cutting-edge technologies. From continuous glucose monitors to AI-powered apps and sensor to…
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Alzheimer’s, Parkinson’s dementia, and other neurodegenerative diseases continue to be challenging, but now new science has led to a better understanding of the natural repair mechanisms in the brain. This, in turn, has generated new options for innovative treatments, and one such approach has entered late-stage human clinical trials. Dr. Mark Litt…
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“You have to invest into change. You cannot invest into stasis. Daniel Kimerling has a keen eye for the trends, technologies, and cultural shifts that are going to be big. A decade ago, he took an insight – that developers needed powerful tool so they could embed banking services into their apps – and launched Standard Treasury, the very first bank…
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This week, Dr. Daniel Bloomfield from Anthos Therapeutics discusses the prevalence and dangers of blood clots, particularly in patients with cancer. Dr. Bloomfield explains the difference between normal and abnormal blood clotting, the risks associated with blood clots in arteries and veins, and the challenges in balancing clot prevention with the …
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A highlight reel that will will help you find great episodes in the Crafted show archive, featuring some of the incredible founders and product builders we featured in 2023. You'll hear voices belonging to the founders of Gusto, Lattice, Monte Carlo, Moov, Wevr, PS, as well as from senior leaders at AWS, Redesign Health, Betterment, Flatiron Health…
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Discover the world of deep tech investing with the Amadeus Team in our latest podcast episode. In this episode, we introduce you to our Early Stage investing team and explore their diverse backgrounds and interests within the deep tech sector. The conversation investigates why deep tech stands out as an investment opportunity. From revolutionary ad…
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Not just seeking treatment for every disease, but making sure the treatments we have already developed are being used in every possible way. I speak with Dr. David Fajgenbaum (Fay-gen-baum), a Professor of Translational Medicine and Human Genetics at the University of Pennsylvania School of Medicine, and President of Every Cure.…
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We're not building a set of blogs or something like that where the domain is well understood. We're really pushing the forefront of what people are doing with vessels and optimization. "The effect of global shipping on the climate is hard to overstate," reports The New York Times. "Cargo shipping is responsible for nearly 3 percent of global greenh…
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When is a medical technology company more than a medical technology company? We’ll hear all about it when I speak with Dave Pacitti, the President and Head of the Americas at Siemens Healthineers. They’re out to solve problems bigger than the products they are known for.By Moira Gunn
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Explore what 2024 is going to look like for tech investors and deep tech startups across the world in the first Amadeus & Friends episode of the year, featuring our CEO Anne Glover and Nick Kingsbury, Partner in our Early Stage Fund. The conversation touches on how fundraising naturally reflects the economic cycle, putting the currently less-than-e…
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** Please take this three-minute survey to help us create more great Crafted episodes. http://tinyurl.com/craftedsurvey ** Last week, on Thursday January 18th at 4:49pm Eastern, a SpaceX Crew Dragon capsule on top of a Falcon 9 rocket launched from NASA’s Kennedy Space Center in Florida on its way to the International Space Station. On board are 4 …
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