Welcome to BIOTECH NATION !!! With understandable interviews requiring no background in science, BTN attracts a wide global audience. From everyday people looking for hope in treatments in development, to bioentrepreneurs interested in the experience of their fellow travelers, to venture capitalists looking for possibilities in cutting-edge breakthroughs, to scientists simply interested in the work of others, BioTech Nation is the voice of human endeavor, driving science to new realities for ...
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Amadeus Capital Partners has been a trailblazer for three decades, investing in people who create transformational technologies and sustainable businesses. We’ve backed nearly 200 startups and scaleups across Europe and, more recently, in Latin America. In Amadeus and Friends, you’ll hear from some of the world’s greatest innovators in quantum computing, AI, biotech and more, sharing their commercial journeys, the highs and the lows, and how they’ve approached commercialisation with the supp ...
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Solving Genetic Diseases??? Dr. Neil Kumar, Founder & CEO, BridgeBio Pharma
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This week on Biotech Nation, Dr. Neil Kumar, founder and CEO of BridgeBio Pharma. Dr. Kumar emphasizes that genetic diseases, particularly Mendelian diseases caused by single gene mutations, are solvable due to advancements in genetic measurement and understanding. He discusses BridgeBio Pharma's innovative corporate structure, which consists of mu…
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The Next Ozempic or Wegovy... But Without the Injection??? Dr. Steffen-Sebastian Bolz, CSO, Aphaia Pharma
25:16
25:16
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What’s next after Ozempic and Wegovy and the like? How about a drug in development which releases all the relevant hormones, and not just GLP-1. And doesn’t require injecting. Dr. Steffen-Sebastian Bolz from Aphaia (ah-phi-ah) Pharma explains their approach, currently in Phase 2.By Moira Gunn
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FDA Approval! A New Model for BioPharma... Dr. Sam Blackman, Founder & Head of Research and Development, One Day Biopharmaceuticals
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31:10
This week on BioTech Nation, Dr. Sam Blackman, Founder and Head of Research and Development from Day One Biopharmaceuticals, shares the story behind the FDA approval of a groundbreaking drug for the most common childhood brain cancer. He talks about their innovative approach to starting a biopharma company and how it led to a newly FDA approved dru…
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Everybody Has a Thyroid... What Could Go Wrong??? Dr. Mark Sumeray, CMO of Amolyt Pharma
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28:59
This week we have a best of rerun with Dr. Mark Sumeray from Amolyt Pharma. Dr. Sumeray talks about their innovative approach to treating hormonal conditions. We’ll talk about two – when your parathyroid has been injured or removed, often during thyroid surgery, and another – when the pituitary starts overproducing growth hormone.…
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Wearable Wonders! Dr. Daniel Kraft, Tech Nation Health Chief Correspondent
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This week Dr. Daniel Kraft, Tech Nation Health Chief Correspondent, discusses advanced health tech. Dr. Kraft highlights his use of wearables like the Apple Watch, Oura ring, and non-invasive blood pressure monitors. He also introduces "otherables," which track health without being worn, using devices like cameras and modified WiFi. These technolog…
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Robo-Docs & VR Surgery??? Dr. Daniel Kraft, Tech Nation Health Chief Correspondent
13:56
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This week on BioTech Nation, Dr. Moira Gunn and Dr. Daniel Kraft discuss how robotics, AI, and virtual reality are transforming surgery. These technologies make procedures less invasive and improve training and outcomes worldwide. Future advancements may include tiny robots performing internal procedures. Security is crucial to prevent hacking of m…
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No More Transfusions!!! Dr. John Scarlett, President and CEO of Geron Corporation
16:10
16:10
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Dr. John Scarlett, President and CEO of Geron Corporation talks about their drug Imetelstat for myelodysplastic syndrome (MDS). MDS patients often require frequent blood transfusions, impacting their quality of life. Imetelstat, a telomerase inhibitor, aims to reduce transfusion dependence by targeting cancer cells in the bone marrow. Phase three t…
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Closing the Innovation Gap!!! Dr. Daniel Kraft, Tech Nation Health Chief Correspondent
10:26
10:26
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Dr. Daniel Kraft, Tech Nation Health Chief Correspondent discusses the gap between medical innovation and its adoption into standard practice. He highlights that it typically takes 17 years for a medical discovery to become common practice, but big data and AI could accelerate this. He emphasizes the importance of sharing medical data and initiativ…
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The Virtual Cell??? Dr. Steve Quake, Head of Science at Chan Zuckerberg Initiative
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This week, Dr. Steve Quake from the Chan Zuckerberg Initiative about their goal to tackle all human diseases in the next century. We discuss CZI's innovative approach, including building Biohubs and funding collaborative research. Dr. Quake explains the importance of something called The Virtual Cell project, aiming to use AI to model every human c…
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How Can Sound Deliver Drugs??? Dr. Neal Kassell, Founder & Chair of Focused Ultrasound Foundation
16:48
16:48
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This week on Biotech Nation, I speak with Dr. Neal Kassell about focused ultrasound technology. We discuss its noninvasive approach, its diverse applications in treating various medical conditions, and its potential to revolutionize treatments for diseases like Alzheimer's, Parkinson's, and cancer. Dr. Kassell also shares insights into ongoing clin…
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70% of Breast Cancers and a Link to Prostate Cancer... Dr. Sean Bohen, President & CEO, Olema Oncology
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This week on BioTech Nation, we explore new efforts in treating cancer with Dr. Sean Bohen, President and CEO of Olema Oncology. We discuss progress in treating breast cancer, particularly ER+/HER2- breast cancer, which accounts for 70% of diagnoses this year. They examine the biology behind these cancers and how Olema's lead compound, palazestrant…
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Tiny RNAs, Big Cures!!! Dr. Sanjay Shukla, President and CEO, ATyr (ah-tire) Pharma
19:54
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This week - Dr. Sanjay Shukla, CEO of Atyr Pharma, discusses the revolutionary potential of mRNA technology in creating new medicines. They explore Atyr's pioneering approach to leveraging tRNA fragments for treating pulmonary sarcoidosis and other organ-specific conditions, aiming to improve patient outcomes while minimizing reliance on convention…
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Visionary Women in VC – what the past tells us about the future!
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Amadeus Capital Partners CEO Anne Glover sits down with Catherine La Torre, Independent NED and former CEO of British Patient Capital, to delve into the dynamics of the UK venture capital industry. Catherine shares invaluable insights gleaned from her illustrious career journey, highlighting the remarkable achievements of British Patient Capital in…
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How Can a Treatment Become a Vaccine??? Dr. Peter DeMuth, Chief Scientific Officer at Elicio Therapeutics
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Dr. Peter DeMuth, Chief Scientific Officer of Elicio Therapeutics, discusses the revolutionary approach of detecting cancer at its earliest stages through circulating tumor DNA (ctDNA) tests. Highlighting their innovative treatment method, which aims to train the body's immune cells to recognize and destroy cancer cells, the episode explores the po…
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Cancer Vaccines??? Dr. Chris Pirie, Co-Founder & COO of HDT Bio
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In this week's episode, Dr. Moira Gunn interviews Dr. Chris Pirie from HDT Bio about their novel approach to cancer prevention through vaccines. They discuss leveraging mRNA technology to target specific tumor mutations and prime the immune system to recognize and eliminate cancer cells. Dr. Pirie highlights ongoing efforts to develop vaccines for …
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Redefining Acute Myeloid Leukemia (AML) Treatment!!! Dr. Robert Ang, President & CEO of Vor Biopharma
15:20
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This week I speak with Dr. Robert Ang from Vor Biopharma about their innovative approach to treating acute myeloid leukemia (AML). AML is a type of blood cancer that affects the bone marrow, leading to the overgrowth of cancerous cells. Dr. Ang explains that traditional treatments, such as chemotherapy and stem cell transplants, have limitations an…
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Fighting Inflammation, and Alzheimer's??? Dr. David Bearss, President & CEO Halia Therapeutics
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In this week's episode of BioTech Nation, Dr. David Bearss, President and CEO of Halia Therapeutics, discusses inflammation and its reduction over a lifetime and in response to various incidents. He unveils the inflammasome, a recently discovered protein complex critical in regulating inflammatory responses and its potential in treating chronic dis…
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Photonic’s Quantum Leap: an interview with Stef Simmons and Hermann Hauser
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Manjari Chandran-Ramesh, Partner on our Early Stage investing team embarks on an insightful journey into the cutting-edge realm of quantum computing with industry pioneers Professor Stephanie Simmons from Photonic Inc and Hermann Hauser, co-founder of Amadeus and Board Director of Photonic. The conversation delves into the challenges and opportunit…
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Food as Medicine, A Personalized Prescription... Dr. Daniel Kraft, Tech Nation Health Chief Correspondent
10:21
10:21
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Tech Nation Health, Chief Correspondent Dr. Daniel Kraft discusses the concept of "food as medicine." Dr. Kraft emphasizes the evolving understanding of nutrition and its profound impact on health, advocating for a shift towards personalized nutrition using cutting-edge technologies. From continuous glucose monitors to AI-powered apps and sensor to…
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Repairing Minds, Naturally??? Mark Litton, President & CEO, Athira Pharma
22:38
22:38
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Alzheimer’s, Parkinson’s dementia, and other neurodegenerative diseases continue to be challenging, but now new science has led to a better understanding of the natural repair mechanisms in the brain. This, in turn, has generated new options for innovative treatments, and one such approach has entered late-stage human clinical trials. Dr. Mark Litt…
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Combatting Blood Clots!!! Dr. Daniel Bloomfield, Chief Medical Officer, Anthos Therapeutics
14:31
14:31
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This week, Dr. Daniel Bloomfield from Anthos Therapeutics discusses the prevalence and dangers of blood clots, particularly in patients with cancer. Dr. Bloomfield explains the difference between normal and abnormal blood clotting, the risks associated with blood clots in arteries and veins, and the challenges in balancing clot prevention with the …
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Heartburn, GERD, Cancer??? Dr. Lishan Aklog, CEO of Lucid Diagnostics
22:59
22:59
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Dr. Lishan Aklog from Lucid Diagnostics tells us about the path from GERD to, unfortunately, esophageal cancer, and about Lucid’s two-minute diagnostic test which can detect precancerous cells.By Moira Gunn
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From Tummy Tucks to Drug Trials??? Dr. Eric Merle, Chief Business Innovation Officer, GenoSkin
14:23
14:23
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Dr. Eric Merle from GenoSkin talks about how they are transforming drug discovery using discarded human skin from surgeries like tummy tucks, revolutionizing the process and accelerating drug development timelines.By Moira Gunn
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Innovating tomorrow: Deep tech insights from the Amadeus Early Stage team
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42:00
Discover the world of deep tech investing with the Amadeus Team in our latest podcast episode. In this episode, we introduce you to our Early Stage investing team and explore their diverse backgrounds and interests within the deep tech sector. The conversation investigates why deep tech stands out as an investment opportunity. From revolutionary ad…
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One Drug, Many Diseases??? Dr. David Fajgenbaum, UPenn School of Medicine Professor and President of Every Cure
27:56
27:56
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Not just seeking treatment for every disease, but making sure the treatments we have already developed are being used in every possible way. I speak with Dr. David Fajgenbaum (Fay-gen-baum), a Professor of Translational Medicine and Human Genetics at the University of Pennsylvania School of Medicine, and President of Every Cure.…
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Alcohol-Associated Hepatitis Treatment on the Horizon!!! Dr. Jim Brown, CEO of DURECT
14:52
14:52
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Dr. Jim Brown from DURECT talks about their clinical trials for Alcohol-Associated Hepatitis, a condition for which there is no approved treatment.By Moira Gunn
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Building Technology and Solving Problems!!! Dave Pacitti, President & Head of the Americas, Siemens Healthineers
20:30
20:30
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20:30
When is a medical technology company more than a medical technology company? We’ll hear all about it when I speak with Dave Pacitti, the President and Head of the Americas at Siemens Healthineers. They’re out to solve problems bigger than the products they are known for.By Moira Gunn
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Navigating the 2024 Tech Investment Landscape with Anne Glover and Nick Kingsbury
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39:46
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Explore what 2024 is going to look like for tech investors and deep tech startups across the world in the first Amadeus & Friends episode of the year, featuring our CEO Anne Glover and Nick Kingsbury, Partner in our Early Stage Fund. The conversation touches on how fundraising naturally reflects the economic cycle, putting the currently less-than-e…
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XPrize Foundation and $101 Million!!! Dr. Daniel Kraft, Tech Nation Health Chief Correspondent
11:14
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Tech Nation Health Chief Correspondent Dr. Daniel Kraft talks about the newest XPrize worth an unprecedented $101 Million.By Moira Gunn
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Wound Healing 2.0!!! Dr. Nik Sopko, Chief Scientific Officer at PolarityTE
15:19
15:19
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Dr. Nik Sopko, the Chief Scientific Officer of PolarityTE talks about their design for wound healing. Their first treatment candidate is diabetic foot ulcers.By Moira Gunn
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Harnessing Natural Killer Cells!!! Dr. Eric Vivier, SVP & CSO of Innate Pharma
20:25
20:25
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Dr. Eric Vivier from Innate Pharma in Marseilles tells us about the next wave of immunotherapy treatments – harnessing Natural Killer cells.By Moira Gunn
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Can Every Medicine Be a Pill??? Dr. Ray Stevens, CEO of ShouTi Pharma
24:24
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Dr. Ray Stevens, CEO of ShouTi Pharma, talks about their approach in turning IV drugs into pills. Current projects include Diabetes and obesity, and two Pulmonary and Cardiovascular disorders. And these are just their first candidates …By Moira Gunn
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Gut-Brain Connections to Autism, Parkinson's, and More!!! Dr. Stewart Campbell, CEO Axial Therapeutics
25:38
25:38
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Dr. Stewart Campbell, CEO of Axial Therapeutics, about their groundbreaking work in Autism–related irritability in teenagers, in Parkinson’s, and in complementing the latest cancer treatments.By Moira Gunn
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Ancient Viruses in our DNA??? Dr. Neil Shubin, Professor & Author University of Chicago
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28:55
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On this week’s BioTech Nation University of Chicago professor Dr. Neil Shubin talks about his book “Some Assembly required … Decoding Four Billion Years of Life, from Ancient Fossils to DNA.” Ancient viruses in our DNA? And what about “jumping genes”?By Moira Gunn
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Treating Diseases with Brain Implants??? Nicolas Vachicouras, CEO & Co-Founder Neurosoft Bioelectronics
15:44
15:44
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This week we visit the brain, and look at what a flexible brain implant might do – from sensing how your brain is working to actual treatment. Nicolas Vachicouras from Neurosoft Bioelectronics in Geneva, Switzerland talks about the target for their first treatment: severe tinnitus.By Moira Gunn
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The Next Ozempic or Wegovy... But Without the Injection??? Dr. Steffen-Sebastian Bolz, CSO, Aphaia (ah-phi-ah) Pharma
24:36
24:36
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What’s next after Ozempic and Wegovy and the like? How about a drug in development which releases all the relevant hormones, and not just GLP-1. And doesn’t require injecting. Dr. Steffen-Sebastian Bolz from Aphaia (ah-phi-ah) Pharma explains their approach, currently in Phase 2.By Moira Gunn
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Who Could Forget About Dolly The Sheep??? Sir Ian Wilmut, Director, Scottish Centre for Regenerative Medicine
29:51
29:51
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29:51
We honor Sir Ian Wilmut, the Scottish embryologist who gained worldwide renown as the leader of the scientific research group that cloned the equally famous Dolly. With his recent passing, we air our 2007 BioTech Nation interview, when David Ewing Duncan and I spoke with Dr. Wilmut on the 10th anniversary of Dolly’s birth.…
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Everybody Has a Thyroid... What Could Go Wrong??? Dr. Mark Sumeray, CMO of Amolyt Pharma
28:19
28:19
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28:19
Dr. Mark Sumeray from Amolyt Pharma talks about their innovative approach to treating hormonal conditions. We’ll talk about two – when your parathyroid has been injured or removed, often during thyroid surgery, and another – when the pituitary starts overproducing growth hormone.By Moira Gunn
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VCs in Defence and National Security; the world is changing
43:14
43:14
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Hear from Adrian Jones who runs the UK Defence Investor Network and Nick Kingsbury a partner at Amadeus Capital on why this important sector is now a focus for venture capitalists.By Amadeus Capital Partners
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It’s All About Cancer, and Covid??? Dr. Andrew Allen, President, CEO, & Co-Founder Gritstone Bio
43:28
43:28
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43:28
This week on BioTech Nation, Andrew Allen, President, CEO and Co-Founder of Gritstone Bio – a full spectrum look at how cancer starts and cancer treatments have developed … and what next-generation treatment means today with Gritstone’s work in colorectal cancer. And wait for it … the next generation of Covid vaccines.…
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New Horizons with Nu Quantum: Scaling Up with Quantum Networking
27:29
27:29
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27:29
Explore quantum networking with Carmen Palacios-Berraquero, CEO and Co-founder of Nu Quantum, in our latest podcast episode. In this episode, Carmen and Manjari highlight the importance of interconnecting quantum computers and address the industry's scaling challenges. Nu Quantum offers an innovative approach to scaling through networking and modul…
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Is Medical School Curriculum Outdated??? Dr. Daniel Kraft, Tech Nation Health Chief Correspondent
11:43
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Tech Nation Health Chief Correspondent Dr. Daniel Kraft talks about how Medical Schools decide what to teach. You might be surprised that it’s based on the Flexner Report … written in … 1910. Is it time for a do-over? And what might that be?By Moira Gunn
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Your Digital Twin May Already Exist!!! Dr. Daniel Kraft, Tech Nation Health Chief Correspondent
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Tech Nation Health Chief Correspondent Dr. Daniel Kraft talks about your Digital Twin … your Digital Twin … yes, you have one.By Moira Gunn
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Chips and Beyond: The Evolution of Semiconductors with Amelia Armour and Hermann Hauser
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We’re excited to share our latest podcast episode that sees a captivating discussion with Amelia Armour and Hermann Hauser on revolution and evolution in the semiconductor industry. In this episode, Hermann offers a retrospective on the most pivotal moments, from the birth of the transistor at Bell Labs, Intel’s ground-breaking 4004, the world’s fi…
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A New Approach To Treating Diabetes... Dr. Anthony Japour, President & CEO, iTolerance
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Dr. Anthony Japour, President and CEO from iTolerance in Miami, Florida tells us about implanting insulin-producing cells in your pancreas – it’s been tried before, but they have a new approach which just might work.By Moira Gunn
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What's New in Digital Health!!! Dr. Daniel Kraft, Tech Nation Health Chief Correspondent
11:17
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Tech Nation Health Chief Correspondent Dr. Daniel Kraft tells us about the explosion of digital health.By Moira Gunn
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Google's First Radio Interview Ever!!! Larry Page & Sergey Brin, Co-Founders, Google
28:15
28:15
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28:15
It’s the 25th anniversary of the founding of Google … and 23 years ago, Google founders - Larry Page and Sergey Brin – came to the Tech Nation studios to do their very first radio interview. There’s lots to learn there, including they believed what humans demanded of search, and why they did what they did.…
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Old Dog, New Tricks ??? ... Dr. Robert Ladner, CEO & Founder, CV6 Therapeutics
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Dr. Robert Ladner, the Founder of CV6 Therapeutics in Belfast, Northern Ireland, tells us about their work to make a cornerstone cancer chemotherapy, even more effective. First trials are in colorectal and gastrointestinal cancers...By Moira Gunn
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Can Good Viruses Kill Deadly Infections??? Tom Ireland, Science Journalist & Author
28:57
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Science journalist Tom Ireland tells us about a burgeoning field of science, which is changing the fight to successfully treat antibiotic infections. His book is “The Good Virus: The Amazing Story and Forgotten Promise of the Phage”.By Moira Gunn
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Beyond the blueprint: How Augmented Reality is set to revolutionise the construction industry with David Mitchell
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31:19
In the next episode of the series, Nick welcomes David Mitchell CEO and Co-founder at XYZ Reality onto the podcast to discuss his company’s mission to revolutionise the construction industry by building from holograms. While 2D drawings continue to be a standard practice on construction sites, they aren't the most intuitive language for human inter…
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