TWiP is a monthly netcast about eukaryotic parasites. Vincent Racaniello and Dickson Despommier, science Professors from Columbia University, deconstruct parasites, how they cause illness, and how you can prevent infections.
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The podcast for microbe lovers: reporting on exciting news about bacteria, archaea, and sometimes even eukaryotic microbes and viruses.
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The Milner Centre for Evolution has three main objectives, to ask the big evolutionary questions, to find new technological and clinical applications, and to take evolutionary research out into the community.
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Understanding the Evolution of Eukaryotic Cells - Professor Tom Williams
21:22
21:22
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21:22The Director of the Milner Centre for Evolution, Professor Turi King, talks to Professor Tom Williams, about being part of a study trying to understand the evolution of eukaryotic cells, a formative event in the history of life on Earth.By Milner Centre for Evolution
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TWiP solves the case about the man with abnormal brain MRI, and presents a new case for your solving about a man with some electrolyte issues related to his end-stage renal disease. Hosts: Vincent Racaniello, Daniel Griffin, and Christina Naula Subscribe (free): Apple Podcasts, Google Podcasts, RSS, email Links for this episode Join the MicrobeTV D…
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51
TWiP 269: Peripatetic Martin Grobusch
1:03:54
1:03:54
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1:03:54TWiP travels to Toronto, CA for the American Society for Tropical Medicine and Hygiene conference where they meet up with Martin Grobusch to discuss his career and his work. Hosts: Vincent Racaniello, Daniel Griffin, and Christina Naula Guest: Martin Grobusch Subscribe (free): Apple Podcasts, Google Podcasts, RSS, email Links for this episode Join …
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TWiP discusses a 41-year long human infection with Schistosoma mansoni, and CRISPR screens that reveal genes essential for Cryptosporidium survival in the host intestine. Hosts: Vincent Racaniello, Daniel Griffin, and Christina Naula Subscribe (free): Apple Podcasts, Google Podcasts, RSS, email Links for this episode Join the MicrobeTV Discord serv…
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TWiP solves the case about the female who traveled to Brazil and upon returning home felt movements under her scalp on the back of her head, and present another case for your solving, a man with abnormal brain MRI. Hosts: Vincent Racaniello, Daniel Griffin, and Christina Naula Guest: Eyal Leshem Subscribe (free): Apple Podcasts, Google Podcasts, RS…
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How the Vectors of Antibiotic Resistance Have Evolved - Professor Zamin Iqbal
22:11
22:11
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22:11The Director of the Milner Centre for Evolution, Professor Turi King, talks to Professor Zamin Iqbal, about being part of a study mapping 100 years of bacterial evolution, to understand just how bacteria have become resistant to antibiotics over the last few decades.By Milner Centre for Evolution
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TWiP 266: Wraps and ivermectin for malaria
1:00:52
1:00:52
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1:00:52TWiP explains research showing that treatment of baby wraps with an insect repellent, and oral dosing with ivermectin, are both effective measures to prevent malaria. Hosts: Vincent Racaniello, Daniel Griffin, and Christina Naula Subscribe (free): Apple Podcasts, Google Podcasts, RSS, email Links for this episode Join the MicrobeTV Discord server T…
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TWiP 265: Things that jump are cleaner than things that squat
40:53
40:53
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40:53TWiP solves the case about the parasite check in summer camp, and presents a new case about a woman who traveled to Brazil and developed furuncles on the back of her head. Hosts: Vincent Racaniello, Daniel Griffin, and Christina Naula Subscribe (free): Apple Podcasts, Google Podcasts, RSS, email Links for this episode Join the MicrobeTV Discord ser…
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Evolution, the Fragility of Nature, and How We Can All Make a Difference - Chris Packham
37:17
37:17
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37:17The Director of the Milner Centre for Evolution, Professor Turi King, talks to Chris Packham, the naturalist, nature photographer, television presenter and author, whose best known for presenting Springwatch, Autumnwatch, Winterwatch, programmes about nature, neurodiversity, dinosaurs, cats, dogs and honeybees.…
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Vincent and Daniel discuss research showing that Toxoplasma gondii infection of the brain alters extracellular vesicle production and the communication between neurons and astrocytes. Hosts: Vincent Racaniello and Daniel Griffin Subscribe (free): Apple Podcasts, Google Podcasts, RSS, email Links for this episode Join the MicrobeTV Discord server T.…
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Understanding the Interactions Between Plants and Their Pathogens - Dr Volkan Cevik
19:11
19:11
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19:11The Director of the Milner Centre for Evolution, Professor Turi King, talks to Dr Volkan Cevik, whose research focuses on understanding interactions between plants and their pathogens, as well as understanding how these pathogens evolve.By Milner Centre for Evolution
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TWiP solves the case of the world travelers with poppy-seed size dots embedded in their skin, then present a new case about parasite check in summer camp. Hosts: Vincent Racaniello, Daniel Griffin, and Christina Naula Subscribe (free): Apple Podcasts, Google Podcasts, RSS, email Links for this episode Join the MicrobeTV Discord server Hero: Dr Laur…
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TWiP 262: Do schistosomes affect behavior?
1:03:52
1:03:52
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1:03:52TWiP reviews research suggesting that schistosome infection affect behavior through the gut-brain axis, and Chuck Knirsch joins to reminisce about Dickson Despommier. Hosts: Vincent Racaniello, Daniel Griffin, and Christina Naula Guest: Chuck Knirsch Subscribe (free): Apple Podcasts, Google Podcasts, RSS, email Links for this episode Join the Micro…
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Discovering Ways to Fight Fungal Diseases That Threaten Our Food Security & Health - Dr Neil Brown
19:22
19:22
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19:22The Director of the Milner Centre for Evolution, Professor Turi King, talks to Dr Neil Brown, whose research focuses on discovering new ways to fight major fungal diseases that threaten our food security and health.By Milner Centre for Evolution
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TWiP solves the case of the pregnant woman from Tanzania with dehydration and 3 weeks of bloody stool, a situation that would confuse Ockam but not Dr. Hickam. Hosts: Vincent Racaniello, Daniel Griffin, and Christina Naula Subscribe (free): Apple Podcasts, Google Podcasts, RSS, email Links for this episode Join the MicrobeTV Discord server Hero: Da…
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TWiP explains how circadian clocks of parasite and vector circadian mediate efficient malaria transmission. Hosts: Vincent Racaniello, Daniel Griffin, and Christina Naula Subscribe (free): Apple Podcasts, Google Podcasts, RSS, email Links for this episode Join the MicrobeTV Discord server Clocks mediate malaria transmission (Nat Micro) Hero: Dame B…
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The Evolution of Imperfection: The Science of Why We Aren't and Can't Be Perfect - Professor Laurence Hurst
51:20
51:20
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51:20The Director of the Milner Centre for Evolution, Professor Turi King, talks to Professor Laurence Hurst whose new book titled; The Evolution of Imperfection: The Science of Why We Aren't and Can't Be Perfect, has just been published.By Milner Centre for Evolution
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TWiP solves the case of the man in the Malaysian city of Kucheng who presents with daily fevers and shaking chills, and serve a new clinical puzzle for you to solve. Hosts: Vincent Racaniello, Daniel Griffin, and Christina Naula Subscribe (free): Apple Podcasts, Google Podcasts, RSS, email Links for this episode Join the MicrobeTV Discord server Le…
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Using Machine Learning to Track the Transmission & Evolution of Pathogenic Bacteria: Lauren Cowley
15:25
15:25
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15:25The Director of the Milner Centre for Evolution, Professor Turi King, talks to Dr Lauren Cowley whose research centres around public health and infectious diseases. She works closely with the UK Health Security Agency.By Milner Centre for Evolution
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TWiP describes how a gut commensal protozoan influences respiratory disease outcomes by shaping pulmonary immunity, and body shape variation in lice that parasitize diving hosts. Hosts: Vincent Racaniello, Daniel Griffin, and Christina Naula Subscribe (free): Apple Podcasts, Google Podcasts, RSS, email Links for this episode Join the MicrobeTV Disc…
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TWiP solves the case of the man in the Malaysian city of Kucheng who presents with left arm swelling, and presents a new case for you to decipher. Hosts: Vincent Racaniello, Daniel Griffin, and Christina Naula Subscribe (free): Apple Podcasts, Google Podcasts, RSS, email Links for this episode Join the MicrobeTV Discord server Letters read on TWiP …
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Natural Selection, Genetic Variation and Magic Populations - Dr Paula Kover
18:53
18:53
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18:53The Director of the Milner Centre for Evolution, Professor Turi King, talks to Dr Paula Kover whose research focuses on understanding how an organism's environment affects the evolution of traits under natural selection.By Milner Centre for Evolution
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TWiP 256: Amazing antimalarial drug resistance
1:02:55
1:02:55
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1:02:55TWiP explains a study that carries out selection of Plasmodium falciparum in the presence of inhibitors to identify determinants of drug resistance, and a paleoparasitological analysis of a 5th–16th c. CE latrine. Hosts: Vincent Racaniello, Daniel Griffin, and Christina Naula Subscribe (free): Apple Podcasts, Google Podcasts, RSS, email Links for t…
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How Your Sex and Your Environment Affect Your Hearing - Professor Turi King
14:42
14:42
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14:42Professor Turi King discusses the results of a scientific paper about the evolution of hearing, which explores the combined impact of biological and environmental factors on how our ears respond to sound. The study was the brainchild of Dr. Patricia Balaresque who got really interested in the different factors, such as our sex or environment, that …
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Michelle Labrunda joins TWiP to solve the case of the Georgian in Guinea with fever and dry cough, and describe a new case for you to solve. Hosts: Vincent Racaniello, Daniel Griffin, and Christina Naula Guest: Michelle Labrunda Subscribe (free): Apple Podcasts, Google Podcasts, RSS, email Links for this episode Join the MicrobeTV Discord server Le…
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Understanding How Speciation Takes Place - Dr Leslie Turner
15:29
15:29
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15:29The Director of the Milner Centre for Evolution, Professor Turi King, talks to Dr Leslie Turner about her research on our understanding how speciation takes place.By Milner Centre for Evolution
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TWiP explains a study which finds that tissue spaces are reservoirs of antigenic diversity for Trypanosoma brucei, then remembers our departed colleague Dickson Despommier. Hosts: Vincent Racaniello, Daniel Griffin, and Christina Naula Click arrow to play Download TWiP #254 (88 MB .mp3, 61 minutes) Subscribe (free): Apple Podcasts, Google Podcasts,…
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Primates of the Caribbean, Science Communication and Perceptions of Evolution - Professor Ben Garrod
28:58
28:58
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28:58Ahead of the Milner Centre for Evolution's Darwin Day lecture 2025, Professor Turi King spoke with Professor Ben Garrod about his career, his involvement in science communication and his passion for all things evolution.By Milner Centre for Evolution
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TWiP solves the case of the man with somnolence and something extra-erythrocytic, and presents a new puzzle for you to solve. Hosts: Vincent Racaniello, Daniel Griffin, and Christina Naula Subscribe (free): Apple Podcasts, Google Podcasts, RSS, email Links for this episode Join the MicrobeTV Discord server Letters read on TWiP 253 New Case 26-year-…
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The Evolution and Ecology of Fungi and Fungal Interactions That Matter to Us - Dr Daniel Henk
25:29
25:29
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25:29The Director of the Milner Centre for Evolution, Professor Turi King, talks to Dr Daniel Henk whose research focuses on the evolution and ecology of fungi.By Milner Centre for Evolution
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TWiP 252: For malaria vaccine, mosquito is the needle
54:27
54:27
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54:27TWiP discusses a study of the safety and immunogenicity of a late liver-stage attenuated malaria parasite delivered by mosquito bite. Hosts: Vincent Racaniello, Daniel Griffin, and Christina Naula Subscribe (free): Apple Podcasts, Google Podcasts, RSS, email Links for this episode Join the MicrobeTV Discord server Live attenuated malaria vaccine (N…
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TWiP solves the case of the woman who went to Belize and notices a lesion on her face, and presents a new clinical case for you to solve. Hosts: Vincent Racaniello, Daniel Griffin, and Christina Naula Subscribe (free): Apple Podcasts, Google Podcasts, RSS, email Links for this episode Join the MicrobeTV Discord server Letters read on TWiP 251 New C…
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TWiP 250: Gut bacteria help Trichinella suppress colitis
51:46
51:46
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51:46TWiP reviews a study showing that the gut microbiota is essential for suppression of colitis by Trichinella spiralis. Hosts: Vincent Racaniello, Daniel Griffin, and Christina Naula Subscribe (free): Apple Podcasts, Google Podcasts, RSS, email Links for this episode Join the MicrobeTV Discord server Gut bacteria and Trichinella suppression of coliti…
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TWiP solves the case of the middle-aged man with eosinophilia and a history of sexual activity with paid sex workers in Okinawa, and presents a new case for you to solve. Hosts: Vincent Racaniello, Daniel Griffin, and Christina Naula Subscribe (free): Apple Podcasts, Google Podcasts, RSS, email Links for this episode Join the MicrobeTV Discord serv…
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How Bacteria Evolve by Getting DNA From Family and Friends - Professor Zamin Iqbal
22:24
22:24
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22:24The Director of the Milner Centre for Evolution, Professor Turi King, talks to Professor Zamin Iqbal about his research that uses computers to look at the genetic makeup of disease-causing bacteria to understand how they evolve and how they're becoming resistant to antibiotics.By Milner Centre for Evolution
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TWiP 248: Toxoplasma reduces Alzheimer's disease
1:06:59
1:06:59
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1:06:59TWiP reviews the observation that infection of Azlheimer's disease mice with Toxoplasma gondii reduces brain amyloid density globally and regionally. Hosts: Vincent Racaniello, Dickson Despommier, Daniel Griffin, and Christina Naula Subscribe (free): Apple Podcasts, Google Podcasts, RSS, email Links for this episode Join the MicrobeTV Discord serve…
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The Evolution of Infectious Bacteria and the Spread of Antimicrobial Resistance - Professor Ed Feil
20:31
20:31
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20:31The Director of the Milner Centre for Evolution, Professor Turi King, talks to Professor Ed Feil about his research using genetics to understand the evolution and spread of infectious bacteria of humans and animals, as well as antimicrobial resistance, which is a major threat to global health and food security.…
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TWiP solves the case of the Manhattan man with pain on urination or ejaculation, and presents a new case for you to solve. Hosts: Vincent Racaniello, Dickson Despommier, Daniel Griffin, and Christina Naula Subscribe (free): Apple Podcasts, Google Podcasts, RSS, email Links for this episode Join the MicrobeTV Discord server Hero: Charles Louis Alpho…
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TWiP 246: Everything spiral: a worm in a hurry
1:23:52
1:23:52
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1:23:52TWiP taps into Dickson's knowledge of Trichinella to discuss an outbreak in humans who consumed rare bear meat, and the impact of globalization and climate change on the epidemiology of the species. Hosts: Vincent Racaniello, Dickson Despommier, and Daniel Griffin Subscribe (free): Apple Podcasts, Google Podcasts, RSS, email Links for this episode …
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Myths, Misconceptions and the Challenges of Bat Conservation - Associate Professor Emma Stone
20:58
20:58
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20:58The Director of the Milner Centre for Evolution, Professor Turi King, talks Associate Professor Emma Stone about her research. Emma leads the Bat Conservation Research Lab. Her research is around conservation biology, in particular the behavioural and ecological responses of wildlife to changes in the environment. She's also recently been awarded a…
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TWiP 245: Flying purple people eater with Ben LaBrot
1:16:22
1:16:22
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1:16:22Founder of Floating Doctors Ben LaBrot joins TWiP to solve the case of the 1 year old in northeastern Panama with a fatal leg infection, followed by a discussion of the history and mission of Floating Doctors. Hosts: Vincent Racaniello, Daniel Griffin, and Christina Naula Guest: Ben LaBrot Subscribe (free): Apple Podcasts, Google Podcasts, RSS, ema…
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Lilach Sheiner joins TWiP to talk about her career and her work on engineering Toxoplasma gondii secretion systems for intracellular delivery of multiple large therapeutic proteins to neurons. Hosts: Vincent Racaniello, Dickson Despommier, and Christina Naula Guest: Lilach Sheiner Subscribe (free): Apple Podcasts, Google Podcasts, RSS, email Links …
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TWiP solves the case of the Woman with White Worms, and submits a new case involving a 1 year old in northeastern Panama with a fatal leg infection. Hosts: Vincent Racaniello, Dickson Despommier, Daniel Griffin, and Christina Naula Subscribe (free): Apple Podcasts, Google Podcasts, RSS, email Links for this episode Join the MicrobeTV Discord server…
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TWiP reviews a study showing that intestinal helminth infection impairs vaccine-induced T cell responses through an IL-10 pathway, which compromised protection against antigenically drifted SARS-CoV-2 variants. Hosts: Vincent Racaniello, Daniel Griffin and Christina Naula Subscribe (free): Apple Podcasts, Google Podcasts, RSS, email Links for this …
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Identifying the Multiple Drivers of Cactus Diversification - Dr Nick Priest
18:15
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18:15Professor Turi King, director of the Milner Centre for Evolution, discusses Dr Nick Priest's research paper into the identification of the multiple drivers of cactus diversification, published in Nature Communications.By Milner Centre for Evolution
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The Evolution of Sex Roles: The Importance of Ecology & Social Environment - Professor Tamás Székely
16:22
16:22
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16:22The Director of the Milner Centre for Evolution, Professor Turi King, talks to Professor Tamás Székely about his latest scientific paper titled, The Evolution of Sex Roles: The Importance of Ecology and Social Environment, which has just been published in the Proceedings of the National Academy of Sciences.…
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TWiP 241: There once was a patient from China
1:14:57
1:14:57
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1:14:57By Vincent Racaniello
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Cases of Whooping Cough Are on the Rise: Is There Anything We Can Do About It?
20:59
20:59
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20:59The Director of the Milner Centre for Evolution, Professor Turi King, talks to Professor Andrew Preston about his research into the group of organisms called Bordetella. The most prominent member of the Bordetella group is Pertussis which causes Whooping cough, a disease that is on the rise again.By Milner Centre for Evolution
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TWiP 240: A daily history of malaria with Sean Murphy
57:17
57:17
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57:17Sean Murphy joins TWiP to discuss his career and the work of his laboratory to assess the daily natural history of asymptomatic Plasmodium infections in adults and older children in Katakwi, Uganda. Hosts: Vincent Racaniello, Dickson Despommier and Christina Naula Guest: Sean Murphy Subscribe (free): Apple Podcasts, Google Podcasts, RSS, email Link…
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Mammalian Sexual Dimorphism Is Associated With Changes in Sizes of Brain Development Gene Families
9:29
9:29
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9:29The Director of the Milner Centre for Evolution, Professor Turi King, talks to Dr Benjamin Padilla-Morales about the research paper he is first author on, and that has just been published in Nature Communications, titled: Sexual size dimorphism in mammals is associated with changes in the size of gene families related to brain development.…
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