"The Long Run" Antarctic explorer Ernest Shackleton would appreciate today's biotech. Scientific entrepreneurs of the 21st century must be ready for what Shackleton called the “hazardous journey, bitter cold, long months of complete darkness, constant danger, safe return doubtful, honor and recognition in case of success.” Today, the men and women who strive to apply science for the betterment of human health have a historic opportunity. They need stamina and resilience to achieve something ...
…
continue reading
1
Ep165: Zach Hornby on Tackling Cancer Drug Resistance
1:02:45
1:02:45
Play later
Play later
Lists
Like
Liked
1:02:45
Zach Hornby, CEO of San Diego-based Boundless Bio, on tackling cancer drug resistance.By Timmerman Report
…
continue reading
1
Ep164: Ted Love and Alan Anderson on Raising the Bar for Sickle Cell Disease Patients
56:39
56:39
Play later
Play later
Lists
Like
Liked
56:39
Ted Love, chairman of BIO, and Dr. Alan Anderson, executive director of Sickle Forward, on how to improve quality of life for sickle cell disease patients around the world.By Timmerman Report
…
continue reading
1
Ep163: Sarah Boyce on RNA Medicines for Muscle Diseases
1:08:19
1:08:19
Play later
Play later
Lists
Like
Liked
1:08:19
Sarah Boyce, CEO of San Diego-based Avidity Biosciences, on RNA medicines for rare muscle diseases.By Timmerman Report
…
continue reading
1
Ep162: Sean McClain on AI for Biologic Drug Discovery
1:05:59
1:05:59
Play later
Play later
Lists
Like
Liked
1:05:59
Sean McClain, CEO of Absci, on using AI to speed up biologic drug discovery.By Timmerman Report
…
continue reading
1
Ep161: Jeff Stein on a Long-Lasting Flu Drug
1:08:51
1:08:51
Play later
Play later
Lists
Like
Liked
1:08:51
Jeff Stein, CEO of San Diego-based Cidara Therapeutics, on a long-lasting drug against flu.By Timmerman Report
…
continue reading
1
Ep160: Abe Ceesay on Precision Neuroscience
1:08:48
1:08:48
Play later
Play later
Lists
Like
Liked
1:08:48
Abe Ceesay, CEO of Boston-based Rapport Therapeutics, on a precision medicine approach to neuroscience drug discovery.By Timmerman Report
…
continue reading
1
Ep159: Jimi Olaghere on Being Functionally Cured of Sickle Cell Disease
1:07:22
1:07:22
Play later
Play later
Lists
Like
Liked
1:07:22
Jimi Olaghere is one of the first patients to have been functionally cured of sickle cell disease with a CRISPR gene-edited cell therapy.By Timmerman Report
…
continue reading
1
Ep158: David Younger and Randolph Lopez on SynBio & AI for Discovery
1:00:44
1:00:44
Play later
Play later
Lists
Like
Liked
1:00:44
David Younger and Randolph Lopez, co-founders of A-Alpha Bio, on using synthetic biology and AI to discover new biologic drugs.By Timmerman Report
…
continue reading
1
Ep157: Vineeta Agarwala of A16Z on Investing in AI for Drug Discovery
56:33
56:33
Play later
Play later
Lists
Like
Liked
56:33
Vineeta Agarwala, general partner at A16Z's Bio & Health fund, on investing in AI for drug discovery.By Timmerman Report
…
continue reading
1
Ep156: David Liu on New Tools and Techniques for Biology
1:52:57
1:52:57
Play later
Play later
Lists
Like
Liked
1:52:57
David Liu, professor of chemistry at Harvard University and co-founder of multiple biotech companies, including Beam Therapeutics and Prime Medicine.By Timmerman Report
…
continue reading
1
Ep155: Valerie Daggett on Early Detection, and Treatment, of Alzheimer's
1:02:37
1:02:37
Play later
Play later
Lists
Like
Liked
1:02:37
Valerie Daggett, founder and CEO of Seattle-based AltPep, on early detection and treatment of Alzheimer's.By Timmerman Report
…
continue reading
1
Ep154: Robert Ang on CRISPR to Protect Bone Marrow & Attack Cancer
1:03:14
1:03:14
Play later
Play later
Lists
Like
Liked
1:03:14
Robert Ang, CEO of Cambridge, Mass.-based Vor Bio, on using CRISPR gene editing to alter bone marrow transplants and improve treatment of acute myeloid leukemia.By Timmerman Report
…
continue reading
1
Ep153: Rick Young on Studying Gene Expression for Drug Discovery
1:01:43
1:01:43
Play later
Play later
Lists
Like
Liked
1:01:43
Rick Young, professor at MIT and co-founder of Syros Pharmaceuticals, CAMP4 Therapeutics, Omega Therapeutics, and Dewpoint Therapeutics, on studying gene expression for drug discovery.By Timmerman Report
…
continue reading
1
Ep152: Jens Eckstein on Investing in Healthy Aging
1:05:05
1:05:05
Play later
Play later
Lists
Like
Liked
1:05:05
Jens Eckstein, investment partner at Hevolution Foundation, on investing in healthy aging.By Timmerman Report
…
continue reading
1
Ep151: Shelley Force Aldred and Nathan Trinklein on Bispecific Antibodies for Cancer
1:03:55
1:03:55
Play later
Play later
Lists
Like
Liked
1:03:55
Shelley Force Aldred and Nathan Trinklein, co-founders of Rondo Therapeutics, on the opportunity with bispecific antibodies for cancer.By Timmerman Report
…
continue reading
1
Ep150: Jeff Jonker on the Small Molecule Drug Discovery Renaissance
1:03:48
1:03:48
Play later
Play later
Lists
Like
Liked
1:03:48
Jeff Jonker, CEO of San Diego-based Belharra Therapeutics, on the renaissance in small molecule drug discovery.By Timmerman Report
…
continue reading
1
Ep149: Nancy Stagliano on Precision Neuroscience
1:01:53
1:01:53
Play later
Play later
Lists
Like
Liked
1:01:53
Nancy Stagliano, CEO of South San Francisco-based Neuron23, on bringing precision medicine to neuroscience drug discovery.By Timmerman Report
…
continue reading
1
Ep148: Diana Brainard on the Fight Against Infectious Disease
1:03:27
1:03:27
Play later
Play later
Lists
Like
Liked
1:03:27
Diana Brainard, CEO of AlloVir, on leading the fight against infectious diseases.By Timmerman Report
…
continue reading
1
Ep147: Reid Huber on Investing in the Future of Medicine
1:08:41
1:08:41
Play later
Play later
Lists
Like
Liked
1:08:41
Reid Huber, partner at Third Rock Ventures, on investing in the future of medicine.By Timmerman Report
…
continue reading
1
Ep146: Jeff Huber on Life in Tech and Biotech
1:47:05
1:47:05
Play later
Play later
Lists
Like
Liked
1:47:05
Jeff Huber, co-founder and general partner at Triatomic Capital, on his career path in tech, and then biotech.By Timmerman Report
…
continue reading
1
Ep145: Lori Lyons-Williams on Targeted Radiopharmaceuticals for Cancer
1:06:39
1:06:39
Play later
Play later
Lists
Like
Liked
1:06:39
Lori Lyons-Williams, CEO of Abdera Therapeutics, on developing targeted radiopharmaceuticals for cancer.By Timmerman Report
…
continue reading
1
Ep144: Turning the Tables, Rob Perez Interviews Me
1:04:58
1:04:58
Play later
Play later
Lists
Like
Liked
1:04:58
Turning the Tables, Rob Perez Interviews MeBy Timmerman Report
…
continue reading
1
Ep143: Zach Weinberg and Alexis Borisy on Freeing the Biotech Founders
1:10:25
1:10:25
Play later
Play later
Lists
Like
Liked
1:10:25
Zach Weinberg and Alexis Borisy of Curie.Bio on Freeing the Biotech FoundersBy Timmerman Report
…
continue reading
1
Ep142: Fred Appelbaum on how 'Living Medicine' Came to Be
55:54
55:54
Play later
Play later
Lists
Like
Liked
55:54
Fred Appelbaum, a physician, scientist and leader at the Fred Hutchinson Cancer Center, on 'Living Medicine,' his new book about the development of bone marrow transplantation and the rise of cell therapy.By Timmerman Report
…
continue reading
1
Ep141: Colin Hill on Digging Deep into Data, Finding New Drug Targets
1:09:30
1:09:30
Play later
Play later
Lists
Like
Liked
1:09:30
Colin Hill, co-founder and CEO of Aitia, on digging deep into biological datasets and finding new drug targets.By Timmerman Report
…
continue reading
1
Ep140: Yung Lie on Supporting Young Scientists with Bold, Brave Ideas
1:02:40
1:02:40
Play later
Play later
Lists
Like
Liked
1:02:40
Yung Lie, president and CEO of Damon Runyon Cancer Research Foundation, on advancing cancer research by supporting young scientists with bold and brave ideas.By Timmerman Report
…
continue reading
1
Ep139: Kevin Conroy on Early Detection of Cancer
1:08:28
1:08:28
Play later
Play later
Lists
Like
Liked
1:08:28
Kevin Conroy, CEO of Exact Sciences, on early detection of cancer.By Timmerman Report
…
continue reading
1
Ep138: Jodie Morrison on Becoming a Biotech CEO
1:00:17
1:00:17
Play later
Play later
Lists
Like
Liked
1:00:17
Jodie Morrison, acting CEO of Q32Bio, on becoming a biotech CEO.By Timmerman Report
…
continue reading
1
Ep137: Aaron Ring on Immunotherapy for Cancer & More
56:37
56:37
Play later
Play later
Lists
Like
Liked
56:37
Aaron Ring, a scientist at Yale moving to the Fred Hutchinson Cancer Center, on applying immunology and protein engineering for cancer therapy and more.By Timmerman Report
…
continue reading
1
Ep136: Deborah Palestrant on Building Biotech Startups
52:52
52:52
Play later
Play later
Lists
Like
Liked
52:52
Deborah Palestrant, partner at 5AM Ventures and head of the 4:59 initiative, on building biotech startups.By Timmerman Report
…
continue reading
1
Ep135: John Maraganore on Developing a New Class of Medicines
1:03:51
1:03:51
Play later
Play later
Lists
Like
Liked
1:03:51
John Maraganore, former founding CEO of Alnylam Pharmaceuticals, on his life in biotech and developing RNA interference as a new class of medicine.By Timmerman Report
…
continue reading
1
Ep134: Emile Nuwaysir on In Vivo Gene Editing Therapies
1:16:22
1:16:22
Play later
Play later
Lists
Like
Liked
1:16:22
Emile Nuwaysir, CEO of Boston-based Ensoma, on developing off-the-shelf in vivo gene editing therapies.By Timmerman Report
…
continue reading
1
Ep133: Catherine Stehman-Breen on Epigenetic Editing Therapies
1:10:33
1:10:33
Play later
Play later
Lists
Like
Liked
1:10:33
Catherine Stehman-Breen, CEO of Boston-based Chroma Medicine, on developing epigenetic editing therapies.By Timmerman Report
…
continue reading
1
Ep132: Eric Dobmeier on Treating Kidney Disease
1:05:44
1:05:44
Play later
Play later
Lists
Like
Liked
1:05:44
Eric Dobmeier, CEO of Seattle-based Chinook Therapeutics, on new strategies for treating kidney diseases.By Timmerman Report
…
continue reading
1
Ep131: Ryan Watts on Neuroscience Drug R&D
1:05:32
1:05:32
Play later
Play later
Lists
Like
Liked
1:05:32
Ryan Watts, CEO of South San Francisco-based Denali Therapeutics, on neuroscience drug discovery and development.By Timmerman Report
…
continue reading
1
Ep130: David Hallal on a Life in Biotech & the Cell Therapy Wave
1:09:29
1:09:29
Play later
Play later
Lists
Like
Liked
1:09:29
David Hallal, CEO of ElevateBio, on a long career in biotech and the coming 50-year opportunity in cell therapy and gene therapy.By Timmerman Report
…
continue reading
1
Ep129: Joanne Smith-Farrell on Engineered B-Cell Therapies
1:11:43
1:11:43
Play later
Play later
Lists
Like
Liked
1:11:43
Joanne Smith-Farrell, CEO of Cambridge, Mass.-based Be Biopharma, on Engineered B-Cell Therapies for Cancer & Rare Diseases.By Timmerman Report
…
continue reading
1
Ep128: Rick Berke on Building a Biotech Journalism Outlet to Last
1:00:34
1:00:34
Play later
Play later
Lists
Like
Liked
1:00:34
Rick Berke, co-founder and executive editor of STAT, on building a biotech journalism outlet to last.By Timmerman Report
…
continue reading
1
Ep127: Jeb Keiper on Computational Drug Discovery
1:09:41
1:09:41
Play later
Play later
Lists
Like
Liked
1:09:41
Jeb Keiper, CEO of Nimbus Therapeutics, on computational drug discovery, an unusual business model, and an important new Tyk2 inhibitor for psoriasis and other forms of autoimmunity.By Timmerman Report
…
continue reading
1
Ep126: DA Wallach on Becoming a Biotech VC
1:11:38
1:11:38
Play later
Play later
Lists
Like
Liked
1:11:38
DA Wallach, founder and general partner of TIME Bioventures, on becoming a biotech venture investor.By Timmerman Report
…
continue reading
1
Ep125: Barry Greene on a New Drug for Depression
1:04:52
1:04:52
Play later
Play later
Lists
Like
Liked
1:04:52
Barry Greene, CEO of Cambridge, Mass.-based Sage Therapeutics, on plans to introduce a new type of treatment for depression and postpartum depression.By Timmerman Report
…
continue reading
1
Ep124: Shehnaaz Suliman on Delivery of Genetic Medicines
1:09:53
1:09:53
Play later
Play later
Lists
Like
Liked
1:09:53
Shehnaaz Suliman, CEO of ReCode Therapeutics, on lipid nanoparticle delivery of genetic medicines.By Timmerman Report
…
continue reading
1
Ep123: Tariq Kassum on Single-Cell Analysis for Drug Discovery
1:15:26
1:15:26
Play later
Play later
Lists
Like
Liked
1:15:26
Tariq Kassum, CEO of Cambridge, Mass.-based Celsius Therapeutics, on using single cell technology for drug discovery.By Timmerman Report
…
continue reading
1
Ep122: Aetna Wun Trombley on Extracellular Protein Degraders
1:00:04
1:00:04
Play later
Play later
Lists
Like
Liked
1:00:04
Aetna Wun Trombley, CEO of Lycia Therapeutics, on extracellular protein degraders.By Timmerman Report
…
continue reading
1
Ep121: Samantha Truex on Going Upstream Against Severe Asthma
1:03:49
1:03:49
Play later
Play later
Lists
Like
Liked
1:03:49
Samantha Truex, CEO of Upstream Bio, on a new approach to treating severe asthma and other inflammatory diseases.By Timmerman Report
…
continue reading
1
Ep120: Tim Lu on Gene Circuits for Cell Therapy
1:04:14
1:04:14
Play later
Play later
Lists
Like
Liked
1:04:14
Tim Lu, CEO of Senti Biosciences, on developing gene circuits for cell therapy.By Timmerman Report
…
continue reading
1
Ep119: Jo Viney on Discovering Treatments for Autoimmune Disease
1:02:42
1:02:42
Play later
Play later
Lists
Like
Liked
1:02:42
Jo Viney, CEO of Seismic Therapeutic, on discovering new treatments for autoimmune disease.By Timmerman Report
…
continue reading
1
Ep118: Ivan Liachko on Assembling Accurate Genomes and Interactomes
1:08:08
1:08:08
Play later
Play later
Lists
Like
Liked
1:08:08
Ivan Liachko, CEO of Seattle-based Phase Genomics, on assembling accurate genomes and interactomes. He also discusses immigrating from Ukraine as a child, and what brought him and his family to the US.By Timmerman Report
…
continue reading
1
Ep117: Dr. Sanduk Ruit on Restoring Eyesight in the Developing World
1:01:24
1:01:24
Play later
Play later
Lists
Like
Liked
1:01:24
Dr. Sanduk Ruit of the Tilganga Institute in Kathmandu on restoring eyesight with affordable cataract surgery for the developing world.By Timmerman Report
…
continue reading
1
Ep116: Ivana Magovcevic-Liebisch on Precision Neuroscience
58:35
58:35
Play later
Play later
Lists
Like
Liked
58:35
Ivana Magovcevic-Liebisch, CEO of Vigil Neuroscience, on precision neuroscience drug development.By Timmerman Report
…
continue reading