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The Microscopists is a podcast from Bitesize Bio and ZEISS Microscopy that takes you into revealing, entertaining, and personal meetings with the great microscopists of our time. Your host is Dr Peter O’Toole. Peter will help you understand what drives great, successful scientists, what really inspires them and what they enjoy most in life. This set of candid, fun, and engaging interviews serves not only to help inspire upcoming scientists but to show how career tracks and work-life balance ...
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Cryo-Talk

Bitesize Bio

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The 'Cryo-Talk' podcast from Thermo Fisher Scientific and Bitesize Bio brings you the world’s most prominent Cryo-electron microscopists. In each episode of this engaging series, host Eva Amsen explores the fascinating world of cryo-electron microscopy through the eyes of the experts and delves beyond the electron beam into what drives them in their careers, their inspirations, and passions. https://bitesizebio.com/cryotalk/
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#78 — Erin Tranfield is Head of the VIB Bioimaging Core, Ghent. In this episode of The Microscopists, Erin joins Peter O’Toole to discuss her inspirational contribution to microscopy despite enormous personal challenges. She also chats about her time at NASA, her mum's career advice, the exotic countries she has worked in, and lunar dust. Watch or …
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#77 — Kelly Vere is the University Director of Technical Strategy at the University of Nottingham. In this episode of The Microscopists, Kelly joins Peter O’Toole to discuss funding her degree by working as a Junior Medical Technician with no science A Levels. They also chat about the amazing work Kelly has done to champion the work of technicians …
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#S7:E75 — In this episode, Peter O'Toole hosts an entertaining panel discussion with former members of his lab group who have gone on to pursue non-academic science careers. His guests are: • Lotta Katriina Räty, Senior Marketing Manager at Miltenyi Biotec. • Rakesh Suman, Innovation Development Officer at the University of Leeds. • Richard Kasprow…
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#75 — Graham Wright is the Director of the Research Support Centre at A*STAR Agency for Science, Technology and Research. In this episode of The Microscopists, Graham joins Peter O’Toole to discuss his motives for switching from research to running a core facility. They also chat about his exciting move from the UK to Singapore and how he manages h…
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#74 — Julia Fernandez-Rodriguez is the Head of the Centre for Cellular Imaging Core Facility, University of Gothenburg, Sweden, and President of the Core Technologies for Life Sciences (CTLS) Association. In this episode of The Microscopists, Julia joins Peter O’Toole to discuss the role of the CTLS. They also chat about why you shouldn't let the d…
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#73 — John Eriksson is the Director General of Euro-BioImaging. In this episode of The Microscopists, John joins Peter O’Toole to discuss how he fell in love with microscopy and shares some beautiful images from his early career. They also chat about his favorite cities, his liter of tea in the mornings, and Finnish hamburgers. Watch or listen to a…
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#72 — Paul Verkade is a Professor of Bioimaging in the School of Biochemistry at the University of Bristol. In this episode of The Microscopists, Paul joins Peter O’Toole to discuss his inspirations and involvement in developing correlative light and electron micropy (CLEM). He also chats about co-establishing the Wolfson Bioimaging Facility and hi…
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#71 — Timo Zimmermann is Team Leader in Light and Microscopy Service and Development at the European Molecular Biology Laboratory (EMBL) Imaging Centre. In this episode of The Microscopists, Timo joins Peter O’Toole to discuss how the microscopy courses they have attended changed their career paths. They also chat about Timo's stunning recent 3D re…
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#70 — In this special panel discussion, Peter O'Toole is joined by members of the Network of European Bioimage Analysts (NEUBIAS), including: • Elnaz Fazeli, Imaging Specialist in the Department of Anatomy at the University of Helsinki. • Kota Miura, freelance image analyst and Vice Chair of NEUBIAS. • Robert Haase, Group Leader in Bio-image Analys…
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#69 — In this special technology focus episode, Peter O'Toole is joined by experts in Fluorescence Correlation Spectroscopy (FCS), including: • Thorsten Wohland, Professor in the Department of Biological Sciences at the National University of Singapore. • Annette Bergter, Marketing Manager, Business Sector Life Sciences at ZEISS Research Microscopy…
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#68 — Beth Cimini is a Senior Group Leader at the Broad Institute of MIT and Harvard. In this episode of The Microscopists, Beth joins Peter O’Toole to discuss the challenges of developing popular software tools like CellProfiler in academia and why harsh peer review leads to user-friendly software. They also chat about why someone on Twitter got m…
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#67 — In this special episode, Peter O'Toole is joined by Executive Board Members of BioImaging North America (BINA), including: • Alison North, Research Associate Professor and Senior Director at The Rockefeller University. • Claire Brown, Associate Professor & Director, Advanced BioImaging Facility at McGill University. • Nikki Bialy, BINA Progra…
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#66 — In this special episode, Peter O'Toole is joined by researchers from the Latin American community, including: • Andres Kamaid, Researcher at the Institut Pasteur de Montevideo. • Leonel Malacrida, Associate Professor and Head of the Advanced Bioimaging Unit at the Universidad de la República & Institut Pasteur de Montevideo. • Mariana De Niz,…
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#65 — Ronald Germain, M.D. is a Distinguished Investigator and Lab Chief of the Lymphocyte Biology Section at the National Institutes of Health. In this episode of The Microscopists, Ron joins Peter O’Toole to discuss why you need to think like a surfer in science. They also chat about what he does to entertain himself when he gets bored in meeting…
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#12 — Rhys Grinter is Lab Head in the Department of Microbiology at Monash University. In this episode of Cryo-Talk, Rhys joins Eva Amsen to talk about how he uses cryoEM to look at bacterial proteins, including an enzyme that converts air to electricity. They also talk about travel, career breaks, and cooking. Watch or listen to all episodes of th…
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#64 — Jean-Yves Tinevez is a Research Engineer at Institut Pasteur. In this episode of The Microscopists, Jean-Yves joins Peter O’Toole to discuss why he finds supporting other researchers at a core imaging facility so rewarding. They also chat about storing his extensive collection of comic books in his Parisian apartment and some favorite countri…
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#63 — Kedar Narayan (Frederick National Laboratory and National Cancer Institute) joins Peter O’Toole to discuss how he originally wanted to be a designer and never took high school biology because he thought it was icky. They also dive into why developing technologies is demanding and the potential downsides to AI in science. Watch or listen to al…
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#62 — Lucy Collinson (The Francis Crick Institute) and Kirk Czymmek (The Donald Danforth Plant Science Center) join Peter O’Toole to discuss volume EM. Together they highlight what volume EM is, how it has been a quiet revolution, and share resources to help those wanting to get started using this powerful new technology. They discuss how amazingly…
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#11 — Peter Shen is an Assistant Professor of Biochemistry at the University of Utah. In this episode of Cryo-Talk, Peter joins Eva Amsen to talk about the CryoEM 101 course he co-developed and how this led to merit badges for the National Centers for CryoEM. They also talk about boardgames, basketball, and making music. Watch or listen to all epis…
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#61 — Joachim Frank is a Professor of Biological Sciences at Columbia University and winner of the 2017 Nobel Prize in Chemistry for his involvement in the development of CryoEM. In this episode of The Microscopists, Joachim joins Peter O’Toole to discuss how his early interactions with an electron microscope shaped his career and how he considered…
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#10 — Gökhan Tolun is an Associate Professor in the School of Chemistry and Molecular Bioscience at the University of Wollongong in Australia, and Research Group Leader at the Molecular Horizons Research Institute. In this episode of Cryo-Talk, Gökhan joins Eva Amsen to talk about his research, funding challenges in different countries, and how Mol…
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#9 — Bret Freudenthal is Associate Professor in the Department of Biochemistry at the University of Kansas Medical Center. In this episode of Cryo-Talk, Bret joins Eva Amsen to talk about the importance of making CryoEM technologies accessible via shared facilities and the new facility opening in Kansas. They also talk about skiing, barbecuing, and…
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#8 — Ariane Briegel is Professor of Ultrastructural Biology at Leiden University and co-director of the Netherlands Centre for Electron Nanoscopy. In this episode of Cryo-Talk, Ariane joins Eva Amsen to share how she uses cryo-electron tomography to study how microbes interact with their environment. They also talk about Ariane’s initial interest i…
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#7 — Rob Kirchdoerfer is Assistant Professor in the Department of Biochemistry and the Institute for Molecular Virology at the University of Wisconsin-Madison. In this episode of CryoTalk, Rob joins Eva Amsen to talk about using cryoEM to study virus interactions and how he ended up working on cutting-edge research. He also talks about possible fut…
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#60 — In this episode of The Microscopists, Peter O'Toole is joined by three representatives of bioimaging networks in Africa: Caron Jacobs of the African BioImaging Consortium (ABIC), Ben Loos of the South African BioImaging Community (SABI) and Mahmoud Maina of the Biomedical Science Research and Training Centre (BioRTC) at Yobe State University.…
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#59 — Aydogan Ozcan is Chancellor’s Professor and HHMI Professor in the Department of Electrical and Computer Engineering at UCLA Samueli School of Engineering. Aydogan joins Peter to talk about how advances in imaging technology could make security screening less invasive, the importance of communicating science to the public, and why you need to …
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#58 — Laura Waller is Professor in the Department of Electrical Engineering and Computer Sciences at UC Berkeley. In this episode of The Microscopists, Laura joins Peter O'Toole to talk about how she got interested in optics and engineering and what it's like to run a lab. She also talks about her unusual extreme reading hobby, which has seen her r…
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#57 — Michael Albiez is CEO of Carl Zeiss Research Microscopy Solutions. He chats to Peter O'Toole about how Zeiss Microscopy recently won the German Future Prize live on national TV, and he shares what it's like to connect with many different researchers who all use microscopy in their work. We also hear about his aspirations to become a teacher, …
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#56 — Stefan Hell is Director at the Max Planck Institute for Multidisciplinary Sciences in Göttingen and at the Max Planck Institute for Medical Research in Heidelberg. In this episode of The Microscopists, Stefan tells Peter O'Toole about his quest to overcome the diffraction barrier, why he doesn't think of himself as a microscopist, and staying…
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#6 — Mimi Ho is Assistant Professor of Microbiology and Immunology at Columbia University. In this episode of Cryo-Talk, Mimi joins Eva Amsen to talk about her career journey from industry to academia, her support network, and how Mighty the dog has been helping in the lab. She also shares what it has been like to co-host The Plunge podcast. Tune i…
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#55 — Emma Lundberg is Associate Professor of Bioengineering at Stanford, Professor in Cell Biology Proteomics at KTH Royal Institute of Technology, and Head of the Subcellular Section of the Human Protein Atlas. Emma joins Peter O’Toole to talk about crowdsourcing image analysis for the Human Protein Atlas program within the EVE Online virtual gam…
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#54 — Florian Jug is Research Group Leader and Head of the Image Analysis Facility at Human Technopole, Milan. Florian joins Peter O'Toole to discuss his research using AI and machine learning to better analyze and quantify biological data. They chat about his early ambitions in computer science, and he tells us why he enjoys teaching various cours…
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#5 — Mike Cianfrocco is Research Assistant Professor at the University of Michigan Life Sciences Institute and Assistant Professor in the Department of Biological Chemistry at the University of Michigan Medical School. In this episode of Cryo-Talk, Mike joins Eva Amsen to talk about the tools he is developing for cryoEM users, such as COSMIC2. He a…
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#53 — Christian Eggeling is Head of the Department of Biophysical Imaging at the Institute of Photonic Technologies (IPHT, Jena). In this episode of The Microscopists, Christian joins Peter O'Toole to discuss his varied career to date, starting with a degree in physics, a short stint in a biotech company, followed by faculty positions in Oxford and…
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#52 — Wah Chiu is Wallenberg Bienenstock Professor, and Professor of Bioengineering, and Microbiology and Immunology at Stanford University. In this episode of the Microscopists, Wah chats with Peter O' Toole about his pioneering cryoEM work and his research goals of understanding the structural biology of organelles. They also discuss careers in a…
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#4 — Liz Kellogg is Assistant Professor in the Department of Molecular Biology and Genetics at Cornell University. In this episode of Cryo-Talk, Liz joins Eva Amsen to share how she uses cryoEM to learn more about CRISPR-associated transposons. We also hear about the challenges of keeping a new lab going during the early days of COVID and find out …
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#51 — Antje Keppler is the Director of Euro-BioImaging Bio-Hub. In this episode of The Microscopists, Antje joins Peter O'Toole to discuss the recent explosion and expansion of techniques in microscopy and how Euro-BioImaging is helping researchers access these. They also chat about fishing in Scandinavia and her reaction after being told girls sho…
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#50 — Michael Sheetz is the Robert A. Welch Distinguished University Chair in Chemistry at the Department of Biochemistry & Molecular Biology at the University of Texas Medical Branch (UTMB) at Galveston. In this episode of the Microscopists, Michael joins Peter O'Toole to tell us about his new exciting work on cell senescence, and his time living …
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#3 — Yiorgo Skiniotis of Stanford University has been using cryoEM to study transmembrane receptors. In this episode of Cryo-Talk, Yiorgo joins Eva Amsen to chat about the potential of cryoEM to gather more information about signaling pathways. We also hear more about his love of cinema and classic literature, why he’d be a fisherman if he had to p…
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#49 — In this episode, we talk to Elisabeth Bik, former microbiome researcher turned scientific integrity consultant. Elisabeth spends her time searching biomedical literature for inappropriately manipulated photographic images and plagiarized text, and often discusses these on Twitter at @MicrobiomDigest. Following her successful scientific career…
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#2 — Eva Nogales of UC Berkeley and Lawrence Berkeley National Laboratory uses cryoEM to study cellular processes related to cytoskeletal self-assembly and gene expression. In this episode of Cryo-Talk, Eva joins our host Eva Amsen to discuss the use of CryoEM to study complex cell biology systems and more. She chats about her current work while on…
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#48 — In this episode, we talk to David Piston, Professor and Head of Cell Biology and Physiology at the Washington University School of Medicine in St Louis. David's first love was physics—until he was made to take a quantum mechanics class in graduate school! He now has a super successful career in biology, using innovative imaging and biochemica…
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#47 — From an early start in the lab at just 14 years old, to running one of the largest neuroscience groups in the world, Ed Boyden is a Professor and group leader in the Departments of Brain and Cognitive Sciences at MIT, and an HHMI investigator. In this episode, we hear all about how despite his recent awards and huge success, he initially stru…
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#46 — Stefan Terjung is operational manager at the Advanced Light Microscopy Facility in Heidelberg, one of the first microscopy core facilities established at the EMBL. We discuss new microscopy techniques, his favourite school subjects and guilty TV pleasures. We also chat about the excellent networking opportunities conferences can provide, fun …
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#45 — Eija Jokitalo is the Director of the Electron Microscopy Unit at the University of Helsinki, whose work focuses on understanding organelle structure during cell division. We chat about why she believes imaging is key to solving biological problems, alternative career pathways inside a core facility and her outreach work in schools. We also he…
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#44 — Gail McConnell, Professor of Biophotonics at the University of Strathclyde chats to Peter O'Toole about her groundbreaking work developing new imaging techniques on the Mesolens, discusses her career highlights, and remembers the time she once got into trouble at an international conference. We'll discuss creating good work-life balance, and …
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#43 — Elizabeth Villa, a Howard Hughes Medical Institute investigator at UC San Diego talks to Peter O'Toole about the benefits of collaborative projects, the advantages and disadvantages of new microscopy techniques, and establishing fun lab traditions. We'll chat about her early career as a Fulbright Scholar, her movement into biology to work wit…
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#1 — Joachim Frank of Columbia University has spent his career working on EM and cryoEM. In this episode of Cryo-Talk, Joachim joins Eva Amsen to discuss his research and his 2017 Nobel Prize in Chemistry. We’ll hear how he has used peripheral vision to find unexpected opportunities, why he loves fiction writing, and how he balances New York City l…
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#42 — Claire Brown, Associate Professor & Director of the Advanced BioImaging Facility at McGill University, talks to Peter O'Toole about the importance of taking care of your staff, how she successfully set up a lab as a single mom and why simpler techniques are often the better choice. We'll also discover why she got involved with Global BioImagi…
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#41 — Ralf Jungmann, Professor and group leader at the Max Planck Institute of Biochemistry and LMU Munich joins Peter O'Toole in this episode of The Microscopists to discuss the most frightening time in his career, how moving back to Germany from the US was the biggest culture shock and why writing grants is so important. Ralf also shares how 80s …
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