Best Mrd Podcasts (2024)

1
Fasenra Pediatric Asthma Expansion, Xcopri New Delivery Methods, New MRD Endpoint for Myeloma, Mpox PCR Test Home Collection Kit, Dovato for Adolescents With HIV 8:19

2h ago8:19

8:19

Visit nascentmc.com/podcast for full show notes. - The FDA has expanded the approval of benralizumab (Fasenra) to include children aged 6 to 11 with severe eosinophilic asthma, building on its previous approval for patients aged 12 and older. Benralizumab is a monoclonal antibody that targets and reduces eosinophilic inflammation, crucial in the se…

1
FDA makes MRD the basis for AA 8:32

6d ago8:32

8:32

5 reasons that is a bad ideaBy Plenary Session

1
Episode 098: Understanding MRD Testing in CLL

13d ago

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With multiple options for frontline therapy in CLL, MRD has the potential to emerge as a factor that could be considered in our decision-making algorithm for sequencing treatment options. In this week’s episode, we dive into a deeper understanding of the role of MRD testing in CLL. Content: - What is the role of MRD testing in CLL? - What are the t…

1
Patient advocates funded by Pharma 26:14

13h ago26:14

26:14

Patient advocates, Pharma funding, and is MRD a suitable endpointBy Plenary Session

1
Episode 099: Colorectal Cancer Series, Pt. 1 - Intro to Colorectal Cancer

1h ago

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Colorectal cancer is one of the most common cancers diagnosed each year worldwide. This highly anticipated series will take an in-depth look at this disease. In this first episode, we discuss the basics, including staging, tumor markers, and microsatellite instability testing, before tackling the management of colorectal cancer in upcoming episodes…

1
S5 Ep7: The Future of Breast Cancer Care: Blackwood on Personalized Approaches 26:53

4h ago26:53

26:53

In this episode of Targeted Talks, M. Michele Blackwood, MD, FACS, director of breast surgery, Robert Wood Johnson (RWJ), Barnabas Health, director of women’s oncologic health, RWJ Barnabas Health and Rutgers Cancer Institute, and head of breast surgery, Cooperman Barnabas Medical Center, discusses the current landscape of breast cancer treatment a…

1
White Wedding 50:23

2h ago50:23

50:23

This week, Joe talks some wedding talk before Gaspare stops a fight with nothing but teacher skills and a cup of yogurt. The guys debate the sporting life before reading an all time hilarious listener email. Support the show and get 50% off your 1st Factor box, plus 20% off your next box. Head to https://www.factormeals.com/SOCIALSTUDIES50 and use …

1
Jak2V617F clonal hematopoiesis promotes arterial thrombosis; Staphylococcus aureus infection in Sézary syndrome; clinical features of RAC2-related immunodeficiency 26:18

5m ago26:18

26:18

In this week's episode we’ll discuss the mechanism by which Jak2V617F clonal hematopoiesis promotes arterial thrombosis, discuss how Staphylococcus aureus induces drug resistance in cancer T cells in Sézary syndrome, and learn more about the clinical and functional features of RAC2-related immunodeficiency. Featured Articles: Jak2V617F clonal hemat…

1
Beta Blockers After Heart Attacks Don't Work 15:33

19h ago15:33

15:33

Another flawed quality metric. Reviewing the NEJM paper "Beta-Blockers After Myocardial Infarction and Preserved Ejection Fraction".By Plenary Session

1
Cilta-cel for Myeloma, Enhertu for HER2-positive Solid Tumors, Fanapt for Bipolar, Zevtera for Multiple Bacterial Infections, TriClip for Tricuspid Regurgitation, Revumenib for Acute Leukemia 8:40

1d ago8:40

8:40

· Nascentmc.com for medical writing assistance for your company.Visit nascentmc.com/podcast for full show notes Cilta-cel for Myeloma: The FDA approved ciltacabtagene autoleucel (Carvykti; cilta-cel) for adults with relapsed or refractory multiple myeloma who have tried at least one prior therapy including a proteasome inhibitor and an immunomodula…

1
Don't Be a Newb 49:53

1d ago49:53

49:53

Joe tells tales from the "happiest place on earth" aka Baltimore and finds a hill to die on with a passionate fan. Gaspare gets a new tattoo and goes over his house rules before showing a friend his deck. This episode is brought to you by BetterHelp. Give online therapy a try at https://www.betterhelp.com/SOCIALSTUDIES and get on your way to being …

1
Molecular mimicry in aplastic anemia; emicizumab prophylaxis in infants with hemophilia; hydroxyurea reduces infections in SCA 19:54

8d ago19:54

19:54

In this week's episode we'll discuss molecular mimicry in aplastic anemia, novel experiments show that antigens associated with viral infections can mimic epitopes presented on hematopoietic progenitor cells. Then, we'll learn about prophylaxis with subcutaneous emicizumab in infants with hemophilia. Finally we'll see how hydroxyurea is associated …

1
S5 Ep6: Dizman’s Global Pursuit to Cancer Research and Understanding 19:05

8d ago19:05

19:05

In this episode of Emerging Experts, Nazli Dizman, MD, shares the intricacies of her journey towards becoming an oncologist in the United States.By Targeted Talks

1
Dancing Plagues and Nickelodeon 47:25

9d ago47:25

47:25

This week, the boys make a big announcement, before digging into 90's kid TV shows, the dancing plague of the 1500's, evolution, and everyone's favorite objects; doors and wheels. Support the show and get up to 40% off Beam’s Dream Powder. Head to https://www.shopbeam.com/social and use code SOCIAL.

1
Winrevair for PAH, Vafseo for CKD, Ultomiris for NMOSD, Evolut FX+ for TAVR, Vemlidy for Pediatric HBV, Pemgarda for COVID 9:50

8d ago9:50

9:50

Visit nascentmc.com/podcast for full show notes Winrevair for PAH: Sotatercept-csrk (Winrevair) is FDA-approved for treating adults with pulmonary arterial hypertension (PAH), enhancing exercise capacity, improving WHO functional class, and reducing clinical worsening events. It's the first FDA-approved activin signaling inhibitor for PAH, addressi…

1
Review Series on the Influence of the Tumor Microenvironment on the Pathogenesis of B-Cell Lymphomas 32:05

15d ago32:05

32:05

In this bonus episode of Blood Podcast, Associate Editor, Dr. Freda Stevenson is joined by Drs. Karin Tarte, Andrea Radtke, and Leandro Cerchietti to discuss the Review Series on the influence of the tumor microenvironment on the pathogenesis of B-cell lymphomas. Find the full review series in Blood Journal volume 143 issue 12.…

1
Free light chain mass spectrometry in diagnosis and monitoring of AL amyloidosis; T cells of AML patients in remission have distinct RNA signatures; and protective effect of ADAMTS13 in sickle cell mice ... 22:34

21d ago22:34

22:34

In this week's episode we’ll discuss the findings from a study assessing the utility of free light chain mass spectrometry in AL amyloidosis, learn more about distinct single-cell RNA-sequencing signatures of bone marrow T cells of AML patients in remission after an allogeneic stem cell transplant, and discuss why von Willebrand factor clearance is…

1
Blood based and Stool DNA colon cancer screening - Two NEJM papers 26:06

13d ago26:06

26:06

They are shittyBy Plenary Session

1
Episode 097: Treatment of Relapsed/Refractory CLL

14d ago

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This week, we continue our discussion of treatment of CLL, this time focusing on the relapsed/refractory CLL. If you have not done so, we recommend checking out our prior episodes since we will be building on these conversations! Content: -If you suspect your patient has relapsed, what do you do? -What is the approach to treatment in the relapsed/r…

1
Nexletol and Nexlizet for LDL Lowering and CV Risk, Iclusig for ALL, Elahere for Ovarian Cancer, Duvyzat for DMD, Spevigo for Psoriasis, Tryvio for Hypertension, Opsynvi for PAH, Lenmeldy for Juvenile ... 13:43

15d ago13:43

13:43

Nascentmc.com for medical writing assistance for your company. Visit nascentmc.com/podcast for full show notes Visit learnAMAstyle.com for free downloads regarding editing and the AMA Manual of Style tip sheet. Nexletol and Nexlizet for LDL Lowering and CV Risk: The FDA approved bempedoic acid (Nexletol) and its combination with ezetimibe (Nexlizet…

1
Story Time with Mr. D 48:12

16d ago48:12

48:12

This week, Joe reads to a school full of kids before discovering something incredible in his basement. Gaspare does a deep dive on the Iron lung before answering some questions submitted from patreon members, including what star signs they find attractive. Support the show and get 50% off your Factor order at https://www.factormeals.com with code S…

1
Eculizumab in transplant-associated thrombotic microangiopathy; reclassifying malignant monocytosis; targeting tissue factor in antiphospholipid syndrome 20:50

23d ago20:50

20:50

In this week's episode we'll discuss eculizumab in stem cell transplant-associated thrombotic microangiopathy. Then, we'll learn about reclassifying malignant monocytosis, these newly classified cases have distinct mutational and transcriptional profiles. Finally, we'll hear about targeting the tissue factor coagulation initiation complex prevents …

1
Liso-cel for CLL/SLL, Tislelizumab for Esophageal SCC, Resmetirom for NASH, Maralixibat for Cholestatic Pruritus, Guselkumab for UC 8:45

22d ago8:45

8:45

Please visit nascentmc.com/podcast for all the details. Go to learnAMAstyle.com for lots of freebies on AMA Style and the use of AI in medical writing and editing Here is information on the latest US FDA approvals, the week of March 11 – March 15, 2024 Liso-cel for CLL/SLL - The FDA approved lisocabtagene maraleucel (liso-cel; Breyanzi) for adult p…

1
Farm Fresh Cockroaches 44:06

23d ago44:06

44:06

This week, Gaspare and Joe discuss the finer points of Prince Albert Piercings and binky ceremonies. The guys read about some insane classroom hijinks before wondering how much is eating a live cockroach worth? Support the show & get up to 40% off of Beam’s Dream Powder. Head to https://www.beam.com/SOCIAL and use code SOCIAL at checkout…

1
S5 Ep5: FDA Approval Marks Amivantamab's Milestone in EGFR+ NSCLC 22:32

25d ago22:32

22:32

In this episode, Joshua K. Sabari, MD, discusses the FDA approval of amivantamab plus chemotherapy as a first-line treatment for patients with EGFR exon 20 insertion mutation-positive non-small cell lung cancer.By Targeted Talks

1
Identification of rare relapse-initiating stem cells post-transplantation; interferon α impairs erythropoiesis in sickle cell disease; TNFα promotes clonal dominance of KIT D816V+ cells in mastocytosis ... 22:48

30d ago22:48

22:48

In this week's episode we’ll learn more about rare relapse-initiating stem cells in patients with MDS or AML in complete remission post-transplantation, discuss the role of interferon α in erythropoiesis in sickle cell disease, and learn more about how TNFα promotes clonal dominance of KIT D816V+ cells in mastocytosis.…

1
Episode 096: Treatment of CLL

1M ago

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We continue on our journey through chronic lymphocytic lymphoma (CLL), this time focusing our attention to the treatment of CLL. Content: - What are the indications for treatment? - Can I wait to treat and not impact OS? - What is our current approach to treatment ? - Fixed duration vs. indefinite treatment options? ** Want to review the show notes…

1
OTC Glucose Monitor, Semaglutide and CVD risk, Juvederm Additional Indication, Nivolumab in mUC, Zanubrutinib in FL, Donanemab and Alzheimer’s, Tocilizumab Biosimilar, Denosumab Biosimilars, Clobetasol ... 13:04

29d ago13:04

13:04

Here is information on the latest US FDA approvals, the week of March 4 – March 8, 2024 · ChatGPT4 in medical writing and editing—visit learnAMAstyle.com · Nascentmc.com for medical writing assistance for your company. Visit nascentmc.com/podcast for full show notes - **OTC Glucose Monitor**: The FDA has approved the Dexcom Stelo Glucose Biosensor …

1
Strip Club Grinders 42:06

1M ago42:06

42:06

This week, Joe and Gas discuss the culinary details of strip clubs and consult a very special patreon member for the answer to a very difficult question. Gaspare gets to the bottom of presidential privates and Joe considers doing wedgie stuff for money. Support the show and get 10% off your entire order. Go to https://www.thefreezepipe.com and use …

1
How PAR2 signaling drives thrombo-inflammation; pretransfusion hemoglobin levels linked to survival in beta-thalassemia; etoposide is better than its reputation in primary HLH 17:48

1M ago17:48

17:48

In this week's episode we'll discuss PAR2-biased signaling in thrombo-inflammation. Then, we'll learn about how hemoglobin levels are linked to survival in transfusion-dependent beta-thalassemia. Finally we'll hear about how etoposide is better than its reputation in primary HLH—hemophagocytic lymphohistiocytosis. Symptomatic patients treated with …

1
Episode 095: Introduction to CLL/SLL

1M ago

—

This week, we start a new series, this time all about the ins-and-outs of chronic lymphocytic leukemia (CLL) / small lymphocytic lymphoma (SLL)! Whether practicing general internal medicine, hospital medicine, or hematology/oncology, you will likely come across a patient with CLL. First, we go through initial diagnosis of this disease! Content: - W…

1
Mukbanging Raw Chicken 57:41

1M ago57:41

57:41

This week, Gaspare gets a dose of musical theater before he and Joe do a deep dive into the wild wild world of mukbanging. The guys enlist the help of some special guests to find out the answer to that age old question: how much money would cause you to eat raw chicken? Support the show and get 60% off of Green Chef, plus 20% off your next 2 months…

1
Amivantamab for NSCLC, Drug-Coated Balloon for ISR, Ibrutinib Oral Suspension, Epcoritamab for Follicular Lymphoma, Govorestat for Galactosemia, Obeticholic Acid for PBC, Biktarvy for HIV, Roluperidone ... 11:53

1M ago11:53

11:53

Visit nascentmc.com/podcast for full show notes Visit learnamastyle.com for the free course on ChatGPT4 for medical writers and editors. - The FDA has approved amivantamab (Rybrevant) in combination with chemotherapy (carboplatin-pemetrexed) for the first-line treatment of patients with locally advanced or metastatic non-small cell lung cancer (NSC…

1
S5 Ep4: Enhancing Precision in Immunotherapy: CD8 PET-Avidity in RCC 19:03

1M ago19:03

19:03

In this episode of Emerging Experts, Peter Zang, MD, highlights research on baseline CD8 lymph node avidity with 89-Zr-crefmirlimab for the treatment of patients with metastatic renal cell carcinoma and response to immunotherapy.By Targeted Talks

1
Brentuximab vedotin plus dacarbazine or nivolumab in classical Hodgkin lymphoma; loss of CD20 causes resistance to mosunetuzumab in r/r B-cell lymphomas; trogocytosis as a driver of RBC antigen loss 23:02

2M ago23:02

23:02

In this week's episode we’ll discuss the findings from a prospective trial of brentuximab vedotin with dacarbazine or nivolumab in older patients with classical Hodgkin lymphoma, learn more about CD20 antigen loss as a mechanism of resistance to mosunetuzumab in relapsed/refractory B-cell lymphomas, and discuss the role of trogocytosis in red blood…

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