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AMDA ON-THE-GO

Society for Post-Acute and Long-Term Care Medicine

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Explore the field of post-acute and long-term care, with expert interviews, journal article reviews, innovations news, and more. Statements made by guests on this podcast are their own opinions and are not necessarily the positions of the Society. Speakers’ appearance on the program does not imply an endorsement of them, their views, or any entity they represent.
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Pertussis: EXPOSED is developed and funded by Sanofi, and these podcasts are intended for a healthcare professional audience. Pertussis is generally considered to be an infection of childhood – but are adults at risk too? Listen to the “Pertussis: EXPOSED ” podcast series, where world-renowned experts are exploring the global health concern of pertussis infection across all age groups. In the first two episodes, experts will delve into the unanswered questions surrounding pertussis infection ...
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In this week's episode we’ll discuss the mutational and transcriptional landscape of pediatric BCP lymphoblastic leukemia; learn more about the role of platelet-derived TGF-β1 in immune thrombocytopenia; and discuss the findings from a phase 3 trial of mavorixafor in WHIM syndrome. Featured Articles: Mutational and transcriptional landscape of pedi…
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Episode: The Empowering Three-Part Series | Speaking and Listening in Ways That Matter (Part 2 of 3) Host: Diane Sanders-Cepeda, DO, CMD Guest(s): Aya Caspi In This Episode: In this episode, host Diane Sanders-Cepeda, DO, CMD, and special guest Aya Caspi, discuss how to speak and listen in a way that lets others know they matter without having to a…
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In this week's episode we'll discuss new insights on the role of GM-CSF in establishing immune memory. The authors propose that the coordination of opposing immune memory programs, driven by GM-CSF, may be essential to efficient, yet controlled, innate immune responses. After that: Interleukin-1 inhibition in TTP. Researchers explore the potential …
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Introduced by Associate Editor Robert Zeiser, this Review Series focuses on the problem of immune escape by acute myeloid leukemia (AML). The series opens with a review of how AML escapes T-cell–driven elimination and then focuses on how p53 function impinges on AML recognition by immune cells. The series finishes with a summary of new approaches t…
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Episode: June 2024 Host: Karl Steinberg, MD, HMDC, CMD Guest(s): Tess Jones, PhD, LMSW; Barbara Resnick, PhD, CRNP (co-editor-in-chief) In This Episode: In this episode, host Dr. Karl Steinberg, MD, CMD, and co-editor-in-chief Dr. Barb Resnick, PhD, CRNP, will talk with Tessa Jones, PhD, LMSW, about her work entitled, Race and Ethnicity Are Related…
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In this week's episode we’ll discuss the prognostic value of the Chronic Lymphocytic Leukemia International Prognostic Index in the era of targeted therapies, learn how peak ADAMTS13 activity can be used to assess ADAMTS13 conformation and risk of relapse in immune-mediated thrombotic thrombocytopenic purpura, and discuss the findings from a phase …
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Episode: The Empowering Three-Part Series | Building Trust (Part 1 of 3) Host: Diane Sanders-Cepeda, DO, CMD Guest(s): Aya Caspi In This Episode: In this episode, host Diane Sanders-Cepeda, DO, CMD, and special guest Aya Caspi, discuss what to do and say to show care and restore trust when our choices of words and actions have a negative impact on …
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In this week's episode we'll discuss assessing risk profile in Wiskott-Aldrich Syndrome, or WAS. Then, we'll learn about how the loss of DNMT3A confers resistance to interferon-alpha in hematopoietic stem cells carrying the JAK2-V617F mutation. Finally, we'll explore unrelated donor selection for AML patients undergoing hematopoietic stem cell tran…
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In this week's episode we’ll discuss the safety and efficacy of nilotinib with or without cytarabine in Philadelphia-positive acute lymphoblastic leukemia; learn more about thrombosis risk in double heterozygous carriers of Factor V Leiden and prothrombin G20210A and discuss the utility of circulating cell-free tumor DNA in prognostic prediction in…
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Episode: May 2024 Host: Karl Steinberg, MD, HMDC, CMD Guest(s): Geoffrey Gusoff, MD, MBA, MS; Stina Ek, PhD; Paul Katz, MD, CMD (co-editor-in-chief) In This Episode: In this episode, host Karl Steinberg, MD, CMD, and co-editor-in-chief Paul Katz, MD, CMD, will discuss three articles from the May issue. First, they will talk with first author Geoffr…
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In this week's episode we'll learn about fitusiran prophylaxis in patients with hemophilia A or B, with or without inhibitors. Next we'll hear about new findings that heterozygous germline variants in the NBN gene that are linked to increased risk of B-cell acute lymphoblastic leukemia in children. Finally, we'll explore new insights on the histone…
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In this week's episode we’ll discuss the effects of voxelotor on cerebral blood flow in pediatric sickle cell disease, learn more about venous and arterial thrombosis in patients with Vexas syndrome, and discuss differential sensitivity to tyrosine kinase inhibitors in ABL-class acute lymphoblastic leukemia. Featured Articles: The influence of voxe…
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In this week's podcast we'll discuss another step forward in stamping out high-risk myeloma. Then we'll hear about the plasmin-cleaved von Willebrand factor, or VWF, in microthrombosis. Finally we'll hear about new insights into the origins of sickle cell pain. Featured Articles: Daratumumab, carfilzomib, lenalidomide, and dexamethasone with tandem…
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Episode: D2D Edition | Deprescribing of Anticoagulants: The IF, WHEN and HOW, a Discussion with a Cardiologist Host: Sabine von Preyss-Friedman MD, FACP, CMD Guest(s): Nicole Orr, MD; Irene Hamrick MD, CMD In This Episode: In this episode, host Sabine von Preyss-Friedman, MD, FACP, CMD, and special guests Nicole Orr, MD, and Irene Hamrick, MD, CMD,…
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Episode: May 2024 Host: Karl Steinberg, MD, HMDC, CMD Guest(s): Elizabeth Galik, PhD, CRNP (editor-in-chief); Nicole Orr, MD In This Episode: In this episode, host Dr. Karl Steinberg, MD, CMD, and editor-in-chief Dr. Elizabeth Galik, PhD, CRNP, discuss our May issue of Caring for the Ages with guest Nicole Orr, MD. This issue contains and special s…
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In this week's episode we’ll discuss the utility of MRD in identifying patients with NPM1 AML who benefit from allogeneic transplant in first remission, learn more about the contribution of circulating hematopoietic stem/progenitor cell subsets to human hematopoietic hemostasis, and discuss the role of Let-7 miRNAs in regulation of BCL11A transcrip…
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In this week's epside we'll learn about ADAMTS recovery after caplacizumab therapy in patients with immune thrombotic thrombocytopenic purpura. Then, we'll hear about preclinical characterization of sonrotoclax, a potential second-generation BCL2 inhibitor. Finally we'll hear about new insights into the etiology of Castleman disease where researche…
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In this week's episode, we’ll discuss the findings from a study assessing responses after treatment with tisagenlecleucel [LM1] in adults with relapsed/refractory follicular lymphoma, learn more about the association between high microRNA-145 plasma levels and decreased risk of future incident venous thromboembolism, and discuss how epigenetic and …
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In this week's episode, we'll discuss gut microbiota exploitation by CPX-351 in acute myeloid leukemia. Then we'll learn about optimizing anti-myeloma immunity. New research shows that regulatory T cells suppress myeloma-specific immunity during autologous stem cell mobilization and transplantation. Finally we'll discuss among pediatric patients wi…
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Episode: Assisted Living Three-Part Series | Palliative Care and Goals of Care in AL (Part 3 of 3) Host: Diane Sanders-Cepeda, DO, CMD Guest(s): Michael Nash, MD, CMD; Katie O’Brien, MD, CMD In This Episode: In this episode, host Diane Sanders-Cepeda, DO, CMD, and special guests Michael Nash, MD, CMD, and Katie O’Brien, MD, CMD, discuss framing goa…
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Episode: April 2024 Host: Karl Steinberg, MD, HMDC, CMD Guest(s): E-Shien (Iggy) Chang, PhD; Barbara Resnick, PhD, CRNP (co-editor-in-chief) In This Episode: In this episode, host Dr. Karl Steinberg, MD, CMD, and co-editor-in-chief Dr. Barb Resnick, PhD, CRNP, will talk with Dr. E-Shien (Iggy) Chang, PhD, about her work exploring overt racial and e…
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In this week's episode we’ll discuss the mechanism by which Jak2V617F clonal hematopoiesis promotes arterial thrombosis, discuss how Staphylococcus aureus induces drug resistance in cancer T cells in Sézary syndrome, and learn more about the clinical and functional features of RAC2-related immunodeficiency. Featured Articles: Jak2V617F clonal hemat…
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Episode: April 2024 Host: Karl Steinberg, MD, HMDC, CMD Guest(s): Elizabeth Galik, PhD, CRNP (editor-in-chief); Glenn Tillotson; Allison Villegas, PA-C In This Episode: In this episode, host Dr. Karl Steinberg, MD, CMD, and editor-in-chief Dr. Elizabeth Galik, PhD, CRNP, discuss our April issue of Caring for the Ages with special guests Glenn Tillo…
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Episode: RSV Vaccinations in PALTC Host: Diane Sanders-Cepeda, DO, CMD Guest(s): Ann R. Falsey, MD In This Episode: In this episode, host Diane Sanders-Cepeda, DO, CMD, and special guest Ann R. Falsey, MD, will discuss respiratory syncytial virus (RSV) vaccines, the current RSV Advisory Committee on Immunization Practices (ACIP) recommendations, an…
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In this week's episode we'll discuss molecular mimicry in aplastic anemia, novel experiments show that antigens associated with viral infections can mimic epitopes presented on hematopoietic progenitor cells. Then, we'll learn about prophylaxis with subcutaneous emicizumab in infants with hemophilia. Finally we'll see how hydroxyurea is associated …
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In this bonus episode of Blood Podcast, Associate Editor, Dr. Freda Stevenson is joined by Drs. Karin Tarte, Andrea Radtke, and Leandro Cerchietti to discuss the Review Series on the influence of the tumor microenvironment on the pathogenesis of B-cell lymphomas. Find the full review series in Blood Journal volume 143 issue 12.…
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In this week's episode we’ll discuss the findings from a study assessing the utility of free light chain mass spectrometry in AL amyloidosis, learn more about distinct single-cell RNA-sequencing signatures of bone marrow T cells of AML patients in remission after an allogeneic stem cell transplant, and discuss why von Willebrand factor clearance is…
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Episode: March 2024 Host: Karl Steinberg, MD, HMDC, CMD Guest(s): Emily Morgan, MD; Jessica Rice Williams, PhD; Barbara Resnick, PhD, CRNP (co-editor-in-chief); Paul Katz, MD, CMD (co-editor-in-chief) In This Episode: In this episode, host Dr. Karl Steinberg, MD, HMDC, CMD, and co-editors-in-chief Barbara Resnick, PhD, CRNP, and Paul Katz, MD, CMD,…
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In this week's episode we'll discuss eculizumab in stem cell transplant-associated thrombotic microangiopathy. Then, we'll learn about reclassifying malignant monocytosis, these newly classified cases have distinct mutational and transcriptional profiles. Finally, we'll hear about targeting the tissue factor coagulation initiation complex prevents …
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Episode: Assisted Living Three-Part Series | Transitions of Care and Challenges in AL (Part 2 of 3) Host: Diane Sanders-Cepeda, DO, CMD Guest(s): Michael Nash, MD, CMD; Katie O’Brien, MD, CMD; Sing Palat, MD, CMD In This Episode: In this episode, host Diane Sanders-Cepeda, DO, CMD, and special guests Michael Nash, MD, CMD, Katie O’Brien, MD, CMD, a…
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In this week's episode we’ll learn more about rare relapse-initiating stem cells in patients with MDS or AML in complete remission post-transplantation, discuss the role of interferon α in erythropoiesis in sickle cell disease, and learn more about how TNFα promotes clonal dominance of KIT D816V+ cells in mastocytosis.…
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Episode: March 2024 Host: Karl Steinberg, MD, HMDC, CMD Guest(s): Elizabeth Galik, PhD, CRNP (editor-in-chief) In This Episode: In this episode, host Dr. Karl Steinberg, MD, CMD, editor-in-chief Dr. Elizabeth Galik, PhD, CRNP, discuss our March issue of Caring for the Ages. This month, our cover features the last editorial from long-time member of …
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In this week's episode we'll discuss PAR2-biased signaling in thrombo-inflammation. Then, we'll learn about how hemoglobin levels are linked to survival in transfusion-dependent beta-thalassemia. Finally we'll hear about how etoposide is better than its reputation in primary HLH—hemophagocytic lymphohistiocytosis. Symptomatic patients treated with …
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Join special guest, Dr. Swati Gaur, and your host, Dr. Diane Sanders-Cepeda, for this special episode of FMDA’s Journal Club, Antimicrobial Stewardship & Quality. This session focused on the following Learning Objectives: Revisit current guidance and protocols for Antimicrobial Stewardship in our PALTC facilities. Discuss how we are tackling vaccin…
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Certain adult populations are at increased risk of severe disease from pertussis; however, which adults are more susceptible to severe pertussis disease, and how does pertussis affect these adults? Host, Liana Clark, meets with leading experts in the field to explore the affect of pertussis on adults with existing chronic medical conditions and str…
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Pertussis is a highly contagious bacterial infection that is widely considered to be a disease of childhood – but what is the impact of pertussis in the adult population? Host, Liana Clark, meets with leading experts in the field to delve deeper into the impact of pertussis infection in adults and explore how vaccination can protect them against th…
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In this week's episode we’ll discuss the findings from a prospective trial of brentuximab vedotin with dacarbazine or nivolumab in older patients with classical Hodgkin lymphoma, learn more about CD20 antigen loss as a mechanism of resistance to mosunetuzumab in relapsed/refractory B-cell lymphomas, and discuss the role of trogocytosis in red blood…
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Episode: Assisted Living Three-Part Series | Current Landscape of AL (Part 1 of 3) Host: Diane Sanders-Cepeda, DO, CMD Guest(s): Michael Nash, MD, CMD; Katie O’Brien, MD, CMD In This Episode: In this episode, host Diane Sanders-Cepeda, DO, CMD, and special guests Michael Nash, MD, CMD, and Katie O’Brien, MD, CMD, discuss the current state of assist…
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In this week's episode we'll discuss CAR T cells plus ibrutinib for the treatment of relapsed/refractory mantle cell lymphoma. Next, we'll learn about a new SAGA for acute myeloid leukemia. Finally, we'll hear about new evidence that oxygen delivery to tissues can become diffusion-limited during perfusion with stored blood.…
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Episode: February 2024 Host: Karl Steinberg, MD, HMDC, CMD Guest(s): Victoria Shier, PhD, MPA; Barbara Resnick, PhD, CRNP (co-editor-in-chief) In This Episode: In this episode, host Karl Steinberg, MD, CMD, and co-editor-in-chief Barbara Resnick, PhD, CRNP, will talk with Victoria Shier, PhD, MPA, about her work on the association between state dem…
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In this week's episode we’ll report on the findings from a study evaluating the long-term outcomes of pulmonary embolism in children and adolescents, discuss a new mechanism for hereditary angioedema caused by a methionine-379 to lysine substitution in kininogens, and learn more about predictors of unsustained minimal residual disease negativity in…
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In this week's episode we'll discuss extended follow-up from the ZUMA-5 trial of axicabtagene ciloleucel, or axi-cel. Then we'll learn about the role of platelets in binding and clearing senescent red blood cells. Finally, we'll hear about a new risk stratification strategy for lymphomas of the central nervous system, or CNS.…
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Episode: Ageism Two-Part Series | Is Ageism the Cornerstone of our PALTC Infrastructure? (Part 2 of 2) Host: Diane Sanders-Cepeda, DO, CMD Guest(s): Cynthia Kuttner, MD, CMD; Fatima Naqvi, MD, CMD In This Episode: In this episode, host Diane Sanders-Cepeda, DO, CMD, and special guests Cynthia Kuttner, MD, CMD, and Fatima Naqvi, MD, CMD discuss our …
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In this week's episode we’ll discuss the findings from a two-year follow-up study of lisocabtagene maraleucel in relapsed or refractory large B-cell lymphoma, learn more about how reciprocal stabilization of coagulation factor XIII-A and -B subunits influences plasma FXIII concentration, and discuss the findings from a phase 2 study of inotuzumab o…
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Episode: January 2024 Host: Karl Steinberg, MD, HMDC, CMD Guest(s): Gregory L. Alexander, PhD, RN; Micah Segelman, PhD; Paul Katz, MD, CMD (co-editor-in-chief) In This Episode: In this episode, host Karl Steinberg, MD, CMD, and co-editor-in-chief Paul Katz, MD, CMD, will talk with two authors, Gregory L. Alexander, PhD, RN and Micah Segelman, PhD, …
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In this week’s episode, we’ll discuss the association between occupational exposure to anticancer agents in a parent and subsequent cancer in a child. Then we’ll learn about deciphering and disrupting the activation of PIEZO1 in hereditary xerocytosis. Finally, we’ll hear about the assessment of measurable residual disease, or MRD, in patients with…
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Episode: Ageism Two-Part Series | The Culture of Aging and the Bias of Ageism (Part 1 of 2) Host: Diane Sanders-Cepeda, DO, CMD Guest(s): Cynthia Kuttner, MD, CMD; Fatima Naqvi, MD, CMD In This Episode: In this episode, host Diane Sanders-Cepeda, DO, CMD, and special guests Cynthia Kuttner, MD, CMD, and Fatima Naqvi, MD, CMD discuss our attitudes t…
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In this week's episode we’ll discuss the findings from a prospective trial of TCRαβ/CD19-cell depleted HLA-haploidentical transplantation to treat pediatric acute leukemia, learn more about the incidence, clinical characteristics, and survival of malignancy-associated hemophagocytic lymphohistiocytosis in Sweden, and discuss the bone marrow as the …
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Episode: BPSD Bootcamp: What to Do in a Crisis? (Part 2 of 2) Host: Diane Sanders-Cepeda, DO, CMD Guest(s): Tana Whitt, MSN, PMHNP-BC; Charissa Duffy, DNP, MSN, APRN, PMHNP-BC; Anthony Nedelman, PhD In This Episode: In this episode, host Diane Sanders-Cepeda, DO, CMD, and special guests Tana Whitt, MSN, PMHNP-MC; Charissa Duffy DNP, MSN, APRN, PMHN…
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