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Have you ever thought about who the people are behind life-saving breakthroughs? How did they get started in their careers? Why did they choose the Life Sciences? What effect do they hope to cause? These are the questions we explore on The Life Science Effect. Gain insights straight from thought leaders, entrepreneurial game-changers, and business executives leading the Life Sciences. Host Steve Vinson explores what it really takes to be effective in this industry as a leader and innovator w ...
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This week, our guest is trailblazing filmmaker Lee Daniels. At the top, we discuss his fifteen-year journey to the new Netflix film The Deliverance (5:00), Daniels’ relationship to spirituality (9:16), and his memories of directing theatre at eight-years-old (14:55). Then, we dive into the therapeutic quality of filmmaking (17:14), his work as a ca…
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Since 1989 (Sex, Lies, and Videotape), filmmaker Steven Soderbergh has been a pioneering voice in American cinema. Part free-wheeling iconoclast, part exacting technician. Today, we return to our conversation with the legendary artist. First, Soderbergh describes his process making No Sudden Move amid the pandemic (8:38), his ability to push past c…
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We’re so back at the movies… with head of content at The Ringer and co-host of The Big Picture, Sean Fennessey! At the top, Sam and Sean discuss Sean Wang’s Dìdi (8:52), the father-daughter story at the heart of M. Night Shyamalan’s Trap (15:52), and why the documentaries Brats (19:39) and Faye (22:35) make the perfect weekend watch. Then, they tal…
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What’s the difference between an interview and a first date? For the past decade, Amelia Dimoldenberg has been walking that fine line on her hit YouTube series, Chicken Shop Date. The premise is in the title: filmed at various chicken establishments across London, the show features a series of funny (sometimes awkward) ‘dates’ with everyone from Pa…
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Vinson Cunningham has been a staff writer at The New Yorker for the past eight years, covering theater, television, and politics. He joins us this week to unpack his personal debut novel Great Expectations. At the top, we discuss the state of the US election (5:00), the emergence of the new Democratic ticket in Kamala Harris and Minnesota Governor …
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Last fall, Zadie Smith published her prescient historical novel The Fraud. We return to our conversation with the beloved author this week, on the heels of our latest sit-down with writer Taffy Brodesser-Akner. At the top, Smith details her most recent book (7:48), her instinctive writing process (13:37), and the role of projection in her work (20:…
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Taffy Brodesser-Akner (“Fleishman Is in Trouble”) is a staff writer at The New York Times, where she covers everything from The Eras Tour to Tom Hanks. She joins us today to unpack her new book Long Island Compromise (7:30), its central questions about wealth, trauma, and inheritance (11:58), and the real-life crime that inspired the story (12:52).…
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Today, we're revisiting our special conversation with actor Tom Hanks. We begin by discussing his debut novel, The Making of Another Major Motion Picture Masterpiece (5:58), his nomadic upbringing across California (13:28), and the Stanley Kubrick film that made him want to be an artist (19:40). Then, we talk about his early work at the Great Lakes…
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This week, on the heels of our live show with Julia Louis-Dreyfus, we’re presenting a special conversation from her podcast Wiser Than Me. The episode features award-winning author Isabel Allende (The Wind Knows My Name). They discuss motherhood, falling in love again in her seventies, an influential piece of advice by writer Elizabeth Gilbert, and…
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Julia Louis-Dreyfus (Seinfeld, Veep) is a national treasure with more primetime Emmys than any performer in the history of television. Then there’s her latest decade in film: two collaborations with Nicole Holofcener (Enough Said and You Hurt My Feelings) along with a devastating turn in the heart-rending fairytale from A24, Tuesday. Her range is u…
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On the heels of his first Emmy win, actor Ebon Moss-Bachrach joins us on the show to unpack the return of The Bear. At the top, we dive into the making of the hit series (9:22), a powerful scene with co-star Jeremy Allen White (11:20), and how Moss-Bachrach manages to keep adding layers to his portrayal of Cousin Richie (14:26). Then, he describes …
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“You’re never gonna forget where you were last night at 7:30,” says James Carville. “It has the potential to be that consequential.” Carville is regarded as one the most influential (and animated) operators in the Democratic Party. He came to prominence as the chief architect behind Clinton’s 1992 Presidential campaign, and has remained one of the …
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Beloved playwright Annie Baker won the Pulitzer for Drama in 2014 for her play, The Flick. A decade later, she’s releasing her directorial debut, Janet Planet, through A24. We begin by talking about her striking first feature (7:55): the Western Massachusetts origins of the project (11:00), the mother-daughter love story at its center (13:24), how …
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