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First In Human is a biotech-focused podcast that interviews industry leaders and investors to learn about their journey to in-human clinical trials. Presented by Vial, a tech-enabled CRO with episodes launching weekly on Tuesday's. 🎧 Stay in the Loop! For the latest news and updates, visit our website: https://vial.com Follow us on social media for real-time insights: Twitter: https://twitter.com/VialTrials LinkedIn: https://www.linkedin.com/company/vialtrials
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Explore the untapped potential of RNA amplifying therapeutics with the CEO of CAMP4 Therapeutics, Josh Mandel-Brehm. We uncover the power of antisense oligonucleotides in rewriting the narrative for genetic diseases characterized by protein deficiency. Josh takes us behind the scenes of their innovative RNA Actuating Platform (RAP), a map charting …
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Embark on a journey through the neurons and synapses of brain science with William Korinek, the CEO of Astrocyte Pharmaceuticals. In a conversation that fuses the molecular intricacies of neuroprotection with the humanistic pursuit of medical advancement, Bill reveals his unique path from molecular biologist to biotech innovator. Together, we unrav…
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Join as we dive deep into the world of oncology drug development with Bas van der Baan of Lixte. Discover the inspiration behind Lixte's focus on PP2A inhibitors and how this innovative approach is poised to revolutionize cancer treatment by enhancing chemotherapy and immunotherapy responses. Bas shares insights into ongoing clinical trials, regula…
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Dr. Samar Mohanty, president and CSO of Nanoscope Therapeutics joins us to shed light on the revolutionary gene therapy that's giving hope to individuals with retinal degenerative diseases by pioneering a treatment that can re-sensitize the retina to detect low light levels. We open the curtains on their groundbreaking multi-characteristic opsins (…
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Imagine unlocking the secrets to revitalizing the brain's energy centers and turning the tide on neurodegenerative diseases. In this episode, Rob introduces us to CNM-Au8, an oral nanotherapeutic with the potential to recharge failing mitochondria. Our discussion traverses the innovative path Clene has charted, from the drug's conception to the exc…
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Step into the future as Dr. Jason Bock, founder and CEO of CTMC discusses the company's unique approach to accelerating cell therapies from development to testing, and the power of collaboration in reshaping the future of cancer treatment. Listen in as we discuss how CTMC's partnership with MD Anderson is not just technical but deeply human in natu…
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Embark on a quest to unravel the 'undruggable' genome with Alex Federation, Co-founder of Talus Bio. Explore challenges in targeting transcription factors in cancer with Talus's innovative Marmot platform. Discover potential breakthroughs in rare diseases and pediatric cancers, and glimpse into the future of studying transcription factors within li…
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Join Dr. Ahmed Hamdy, CEO of Vincerx Pharma, on a compelling journey through oncology. From co-founding Acerta Pharma to pioneering patient-centric innovations, Dr. Hamdy shares his impactful career. Explore the groundbreaking VersAptx bioconjugation platform, designed to elevate cancer therapies and uncover the delicate balance between clinical ex…
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Have you ever considered the untapped potential of abandoned drugs? Join Dr. Sam Clark to discuss how his personal drive to combat mental illness is leading to breakthroughs in treatments for neurological and psychiatric diseases. Witness how Terran is not only resurrecting discarded medications for new purposes, but also pioneering the next genera…
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Ever wondered how technology could drastically improve early detection in healthcare? Let us take you on a journey with Mark McDonough, President and CEO of ChromaCode, as we unfold the world of molecular diagnostics with a special focus on HDPCR technology. Mark, with his diverse background in the military and healthcare, brings a fresh perspectiv…
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Embark on a journey through the intricate world of biotech with Bogdan Kezevic, co-founder and CEO of Kaleidoscope Bio, and uncover the revolutionary software shaping the future of scientific research. Bogdan's leap from scientist to entrepreneur has led to groundbreaking solutions for the challenges plaguing biotech. In our chat, he shares how dat…
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What does it take to revolutionize the world of vaccines and touch lives across the globe? Join us on a riveting journey with Steven Reed, CEO and co-founder of HDT-Bio, as we explore the creation of the first refined tuberculosis vaccine and dive into the remarkable strides in RNA technology. This episode lifts the veil on the science that could r…
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Join Jeffrey Bacha, a pioneer in the fight against cancer and the creative force behind Rakovina Therapeutics. For 25 years, Jeffrey has been reshaping the industry landscape, and today, he gives us a peek into his world of innovation. We venture into Rakovina's research and development of oncology drugs. exploring their groundbreaking technique co…
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Embark on a fascinating exploration of biotech entrepreneurship, guided by an expert who's been in the trenches: Jonathan Thon, CEO and founder of STRM.BIO. We'll give you an insider's view of his journey from academia to the cutting edge of biotech, unveiling his trailblazing work on platelet production and the transformative potential of extracel…
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Ever wondered how far we've truly come in the realm of gene and cell therapies, and where we're headed next? This captivating conversation with Oscar Segurado, the CMO of ASC Therapeutics, will satisfy your curiosity. Oscar, a veteran in the biopharmaceutical industry, shares fascinating insights on ASC Therapeutics' groundbreaking innovation in pe…
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We’re thrilled to share our enlightening exchange with Spiro Rombotis, the seasoned CEO of Cyclacel. He peels back the curtain on the breakthrough discovery of B53, a commonly mutated gene in cancer patients, and the inspiring success of FADRA, their lead drug in clinical trials. Furthermore, Spiro delves into the highs and lows faced by Cyclacel, …
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Ever wondered about the people who are leading the fight against cancer, developing groundbreaking treatments, and changing lives? Meet Frank Boriello, the mind behind SUPLEXA cell therapy, and the CEO and founder of Alloplex Biotherapeutics. In our conversation, Frank shares the personal backstory that sparked his quest to revolutionize cancer tre…
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Max Darnell, CEO and co-founder of Modulus Therapeutics, takes us through his thrilling journey from bioengineering and systems biology to launching a biotech startup. Max unveils how his team's curiosity and motivation, along with their high throughput discovery platform, are revolutionizing cell and cell therapy component designs. Hear how Modulu…
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Join 30-year industry veteran Pepper Landson, Co-founder and CEO of Praetego as she shares her inspiring journey that led her to tackle Alzheimer's and dementia through the innovative use of amadorins. Pepper's intriguing narrative not only highlights her commitment to the public health crisis surrounding these neurodegenerative diseases, but also …
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Ever wonder how the complexities of gene therapies are addressed from bench to bedside? The creative solutions lie within the innovative approaches of seasoned professionals like Dr. Timothy Miller, Co-Founder, President, & CEO at Forge Biologics. With a fascinating career that interlaces academia, biotech, and entrepreneurship, Dr. Miller brings a…
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What if your vision could be saved by the precise application of innovative biotech? Join us as we talk to David Esposito, President & CEO of ONL Therapeutics, and delve deep into his take on leadership. He shares how his military background has been instrumental in the successful management of clinical trials, particularly when navigating the unpr…
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Does the convergence of tech and biology hold the key to reshaping biotech's data infrastructure? Our recent chat with Alfredo Andere, Co-Founder and CEO at LatchBio, certainly supports this notion. This episode offers a deep dive into Alfredo's journey from being part of the Google Brain team to co-founding Latch Bio - a company that is making wav…
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Embark on a journey into the forefront of biotech with Lucas Siow, the visionary behind ProteinQure, as he unveils the impact of his computational platform on peptide therapeutics and delves into the art of team building. Explore the fusion of medicinal chemistry and high throughput screens, discover the essence of benchmarking in drug discovery, a…
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For episode 38, we sit down with Stephen Doyle, Chief Business Officer at ASLAN Pharmaceuticals. Find out more about the challenges involved in developing innovative treatments and how ASLAN is addressing those difficulties as they work to bring new therapies like their novel atopic dermatitis treatment to the market. First In Human is a biotech-fo…
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For episode 37, we connect with David Bearss, President and CEO of Halia Therapeutics. Learn more about the connection between chronic inflammation and disease, and how Halia is using their novel therapies to treat both inflammatory disorders and neurological diseases. First In Human is a biotech-focused podcast that interviews industry leaders and…
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For Episode 36, we chat with Romain Micol, CEO & Co-Founder of Combined Therapeutics. Stay tuned to learn how Combined Therapeutics is developing unique mRNA-based treatments to better protect the world from infectious disease and cancer. First In Human is a biotech-focused podcast that interviews industry leaders and investors to learn about their…
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For Episode 35, we sit down with Simon Allen, CEO of Anebulo Pharmaceuticals. Find out how Anebulo is addressing the unmet need for treatment of acute cannabinoid intoxication and other substance use disorders with their innovative novel therapeutics. First In Human is a biotech-focused podcast that interviews industry leaders and investors to lear…
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For episode 34, we sit down with Bruno Gagnon [gag-nan], SVP of Global Clinical Operations at Opthea. Learn about how Opthea is working to better the quality of life for those suffering impaired vison by improving visual acuity with their novel therapeutic agent. First In Human is a biotech-focused podcast that interviews industry leaders and inves…
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For episode 33, we connect with Aaron Morris Co-Founder & CEO at PostEra. Find out what the difficult process of drug discovery may look like in the future, and how PostEra is looking to drastically speed it up through the application of AI. First In Human is a biotech-focused podcast that interviews industry leaders and investors to learn about th…
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For episode 32, we chat with Nicolas Tilmans, Founder & CEO at Anagenex. Stay tuned to learn how Anagenex is combining the power of machine learning and biochemistry to revolutionize the drug discovery process. First In Human is a biotech-focused podcast that interviews industry leaders and investors to learn about their journey to in-human clinica…
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For episode 31, we sit down with Ganesh Padmanabhan, CEO at Autonomize AI. Find out how Autonomize AI is working to better contextualize healthcare data by applying human-centric artificial intelligence to the problem. First In Human is a biotech-focused podcast that interviews industry leaders and investors to learn about their journey to in-human…
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For episode 30, we sit down with Craig Lipset, co-chair at the Decentralized Trials & Research Alliance. Learn more about the future of decentralized trials and how the increasing prevalence of remote and hybrid research can lead to more accessible and equitable trial participation. First In Human is a biotech-focused podcast that interviews indust…
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For episode 29, we chat with Aneesh Chopra , President at CareJourney. Stay tuned to hear from the United States first Chief Technology Officer about how the private and public sectors can intersect in the pursuit of solving meaningful world problems. First In Human is a biotech-focused podcast that interviews industry leaders and investors to lear…
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For episode 28 we connect with Trevor Martin, Co-Founder & CEO of Mammoth Bioscience. Learn how Mammoth is utilizing CRISPR technology to develop innovative genetic treatments, and what challenges a platform biotech company like themselves faces as they grow and work towards their goals. First In Human is a biotech-focused podcast that interviews i…
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For episode 27, we sit down with Sean Bohen, CEO of Olema Oncology. Stay tuned to learn what the future of personalized cancer treatment holds, and learn how Olema is helping to address the disparity in available care for women. First In Human is a biotech-focused podcast that interviews industry leaders and investors to learn about their journey t…
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For episode 26, we chat with Margo Georgiadis, CEO & Co-Founder of Montai Health. Find out about Montai’s creative approach to tackling chronic disease by harnessing the power of nature to find safer, more effective treatment options. First In Human is a biotech-focused podcast that interviews industry leaders and investors to learn about their jou…
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For episode 25, we sit down with Dr. Paul Lammers, CEO of Triumvira Immunologics. Stay tuned to learn why having multiple programs in clinical trials can provide a safety net should one program fail and how it adds additional value for investors. First In Human is a biotech-focused podcast that interviews industry leaders and investors to learn abo…
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For episode 24, we speak with Gun-ho Kim, CEO & Founder of Recens Medical. Find out about the Ocu-Cool system: a painless intravitreal injection alternative to chemical anesthesia. First In Human is a biotech-focused podcast that interviews industry leaders and investors to learn about their journey to in-human clinical trials. Presented by Vial, a…
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Sitting down with Sam Whitaker for episode 23, Co-Founder & Co-CEO of Mural Health. We learn about a common feature of vertically integrated businesses that bring together different areas of expertise or skill sets to create a single product. First In Human is a biotech-focused podcast that interviews industry leaders and investors to learn about t…
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For episode 22 we connect with Dr. Kristian Reich, Founder & Chief Scientific Officer of MoonLake Immunotherapeutics. Find out the key things that have contributed to Dr. Reich’s success in raising capital and having to tell his story 521 times. First In Human is a biotech-focused podcast that interviews industry leaders and investors to learn abou…
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For episode 21 we chat with Jeanne Hecht. Jeanne brings 30 years of experience as an executive (CEO and COO) of two different firms and as the founder & CEO of JTH Consulting & Associates advising VC’s, private equities, as well as CEO’s and executives across the life sciences industry. First In Human is a biotech-focused podcast that interviews in…
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Sitting down with Dr. Dina Radenkovic for episode 20. Find out what the CEO & Co-Founder of Gameto had to say about chat GPT and what it could do for healthcare in the next 12 months. First In Human is a biotech-focused podcast that interviews industry leaders and investors to learn about their journey to in-human clinical trials. Presented by Vial…
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For episode 19 we chat with Naheed Kurji, Co-Founder, President, and CEO of Cyclica. Find out why the power of AI-based technologies and neo-biotech are the wave of the future. First In Human is a biotech-focused podcast that interviews industry leaders and investors to learn about their journey to in-human clinical trials. Presented by Vial, a tec…
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For episode 18, we sit down with David Berry, CEO, and Board Director at Valo Health. Having founded over 25 companies, find out what crucial piece of advise he received early on in his career as well as what lead to the success of Valo’s first in human for retina trial last year. First In Human is a biotech-focused podcast that interviews industry…
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For episode 17, we catch up with Dr. Torsten Schröder, Founder & Chief Medical Officer of Perfood. Stay tuned to find out what Dr. Schroders opinion on the future of personalized medicine and what that looks like. First In Human is a biotech-focused podcast that interviews industry leaders and investors to learn about their journey to in-human clin…
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For episode 16, we speak to Alicia Levey, COO at Pionyr Immunotherapeutics. Find out a common mistake among small biotech and why you should invest in the relationships with people on the other side of the table as much as you’re making sure your program is well positioned. First In Human is a biotech-focused podcast that interviews industry leader…
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For episode 15, we chat with Dr. Richard Sachse, Chief Medical Officer at SOTIO. Listen in to find out why early collaboration between clinical and research teams is essential for drug development. First In Human is a biotech-focused podcast that interviews industry leaders and investors to learn about their journey to in-human clinical trials. Pre…
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For episode 14, we connect with Vineet Jain, Co-Founder & CEO of Egnyte. Stay tuned to hear about the common misconceptions with eTMF. First In Human is a biotech-focused podcast that interviews industry leaders and investors to learn about their journey to in-human clinical trials. Presented by Vial, a tech-enabled CRO, hosted by Simon Burns, CEO …
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In episode 13, we chat with Ameet Nathwani, CEO at Dewpoint Therapeutics. Find out why you shouldn’t underestimate the complexity of the biology and the disease as it pertains to global approvals. First In Human is a biotech-focused podcast that interviews industry leaders and investors to learn about their journey to in-human clinical trials. Pres…
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