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DISGRACELAND

Double Elvis Productions

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Musicians. Movie stars. Mayhem. Murder. DISGRACELAND is the award-winning podcast that tells the unbelievable but true stories from the dark side of entertainment history. Rockstars getting away with murder and behaving very badly. Actors engulfed in scandal. Pop stars plotted against and terrorized. Taylor Swift escaping her stalkers. Jerry Lee Lewis allegedly murdering his wife. Brittany Murphy’s suspicious death. Big Lurch, the hip hop star who ate his roommate. The assassination of John ...
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JACC Podcast

American College of Cardiology

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Daily
 
Each week, renowned editor-in-chief of the Journal of the American College of Cardiology (JACC), Valentin Fuster, MD, PhD, MACC, records free podcasts highlighting journal findings. To keep clinicians updated on the most important science emerging in clinical and translational cardiology, Dr. Fuster provides an overview of the weekly edition, as well as a short summary of each manuscript. Encompassing JACC and nine cardiovascular specialty journals, the JACC family of journals rank among the ...
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The '00s Zone

Mark Palermo, Loretta Yu

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Monthly
 
This is a podcast that looks back at the movies of the '00s, and tries to make sense of that seemingly culturally faceless first decade of the new millennium. It's hosted by screenwriter, filmmaker, and sometimes critic Mark Palermo (Detention) and actor Loretta Yu (Blood and Water, Diggstown). Sometimes there are guests (also of some renown).
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Illicit romance. An abduction. An international manhunt. Starlets, sex appeal, and psychopaths. Sexual liberation and a scandalous story that’s almost too scandalous to talk about. These are some of the dark stories inspired by Lana Del Rey, an artist who doesn’t fit into a box, and whose music and image are as evocative and compelling as the myth …
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In the September 3, 2024, JACC issue, a major study evaluates the cardiovascular outcomes of second-line antihyperglycemic agents in type 2 diabetes, comparing SGLT2 inhibitors, GLP-1 receptor agonists, DPP-4 inhibitors, and sulfonylureas. The research reveals that SGLT2 inhibitors and GLP-1 receptor agonists offer superior cardiovascular protectio…
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In this episode, Dr. Valentin Fuster reviews five pivotal studies from September 2024, focusing on antithrombotic strategies and diabetes treatments. Key insights include the efficacy of dual antithrombotic therapy over triple therapy, the benefits of anticoagulation alone post-left atrial appendage occlusion, and the superior cardiovascular outcom…
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In the September 3, 2024, issue of JACC, Dr. Samuel Reinhart and team find that using direct oral anticoagulants alone is associated with fewer adverse events compared to combining them with aspirin after left atrial appendage occlusion. Their large-scale study suggests this streamlined approach might be optimal, though further randomized trials ar…
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In the September 3, 2024, issue of JACC, Dr. Valentin Fuster introduces a pivotal study on Brugada syndrome in children and adolescents. This research, led by Dr. Marco Berganti and colleagues, demonstrates how continuous monitoring with implanted loop recorders provides critical insights into arrhythmias and syncope in young patients, highlighting…
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Dr. Valentin Fuster discusses the Augustus trial’s groundbreaking findings on antithrombotic strategies for atrial fibrillation patients post-acute coronary syndrome or PCI. The study reveals that a regimen of apixaban and a P2Y12 inhibitor—without aspirin—offers superior safety and efficacy, challenging traditional triple therapy approaches.…
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In the September 3rd, 2024 issue of JACC, a new scientific statement delves into antithrombotic strategies for peripheral artery disease (PAD), highlighting the challenges and advancements in treatment. The review emphasizes that while traditional therapies like aspirin and clopidogrel remain crucial, combining aspirin with low-dose rivaroxaban off…
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This week in the After Party, Jake wrestles with the works of problematic genius Alfred Hitchcock and gets your take the dilemma presented by such artists. And as we prepare for next week's episode on the unique artistry of the oft-maligned Lana Del Rey, we want to know: Which entertainers do you think have been unfairly treated by the media? Which…
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Alfred Hitchcock grew up on murder. He was the OG crime junkie; obsessed with true stories of stranglers, bodysnatchers, necrophiliacs, and serial killers. He was also afraid – not so much with these ghoulish figures, but of authority, the dark, crowds, and of being alone. He channeled his obsessions and his fears into some of the greatest movies o…
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Dr. Valentin Fuster discusses a study on the effects of low-dose rivaroxaban combined with aspirin in fragile patients after lower extremity revascularization, focusing on the balance between efficacy and safety. It highlights that while frailty increases the risk of adverse outcomes, rivaroxaban reduces ischemic events but also raises bleeding ris…
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In this episode, Dr. Valentin Fuster covers four original papers focusing on cardiovascular disease. Highlights include the effectiveness of semaglutide in reducing weight and improving heart failure symptoms, long-lasting effects of OPASAN on lipoprotein(a) levels, the impact of low-dose rivaroxaban plus aspirin on fragile patients post-revascular…
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Dr. Valentin Fuster discusses the treatment and diagnosis of transcatheter aortic valve thrombosis, focusing on its manifestations, diagnostic techniques using multi-slice computed tomography, and a proposed treatment algorithm. It highlights the difference between subclinical and clinical thrombosis and provides a detailed approach to managing bot…
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In this episode, Dr. Valentin Fuster provides an overview of a scientific statement on structural cardiac interventions in heart failure. It details advances in percutaneous therapies for ventricular reshaping, valvular heart disease interventions, and tricuspid valve issues, while also highlighting gaps in current treatments and areas for future r…
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Dr. Valentin Fuster discusses a study on the efficacy of semaglutide for treating obesity-related heart failure with preserved ejection fraction, highlighting that the drug significantly reduced body weight and improved heart failure symptoms in both men and women. Notably, women experienced greater weight loss than men, but this did not translate …
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Dr. Valentin Fuster evaluates a deep learning model designed to predict left and right ventricular dysfunction and dilation in congenital heart disease patients using ECG and CMR data. The research demonstrated that AI ECG can reliably identify significant cardiovascular issues, though future work should focus on refining thresholds and validating …
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In this episode, Dr. Valentin Fuster explores findings from the Phase 2 OCEAN-LDO trial assessing the off-treatment effects of the RNA-based drug alpcisiran on lipoprotein(a) [Lp(a)] levels. The study found that high doses of alpcisiran reduced Lp(a) levels by up to 95% during treatment, with a sustained reduction of 27-76% persisting up to 96 week…
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This week in the After Party, Jake looks at Brittany Murphy's mysterious death and the history of bad moms in Hollywood and crime. As we prepare for next week's episode on the brilliant yet problematic Alfred Hitchcock, we want to know: Which films can you not go without despite the horrific behavior of their creators? How do you handle the dilemma…
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When actress Brittany Murphy died of pneumonia at the age of just 32 years old, it seemed that all of Hollywood had questions about her death. All but her husband, who did not find his wife’s death suspicious in the slightest. Then, shortly after, Brittany Murphy’s husband died of the same highly suspect cause of death, pneumonia, and then, things …
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