Allison Park Church is a multi-campus church in Pittsburgh that is committed to changing the world one life at at time. To find out more about Allison Park Church or to connect with us online, check us out at the links below! Website: allisonparkchurch.com Facebook:facebook.com/AllisonParkChurch Twitter: twitter.com/apclife
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ON THE SCENE is a live radio broadcast showcasing the music, film, and arts events in KW each week. Hosted by local musician and podcaster Allison Dyjach, ON THE SCENE provides listings, artist interviews, and local music. Tune in at 7:00pm every Thursday on MidtownRadio.ca. Sponsored by the Downtown Kitchener and Uptown Waterloo BIAs.
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Exploring all things genetics. Dr Patrick Short, University of Cambridge alumnus and CEO of Sano Genetics, analyses the science, interviews the experts, and discusses the latest findings and breakthroughs in genetic research. To find out more about Sano Genetics and its mission to accelerate the future of precision medicine visit: www.sanogenetics.com
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We have an adoption anointing on our church. Pastor Kyler Sederwall shares what that means and how it applies to each of us.By Kyler Sederwall
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EP 137: Mavis Machirori on promoting equity, diversity, and social justice in genomics research
41:40
41:40
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0:00 Intro 1:30 Mavis’ career arc, from starting as a midwife to researching medical innovation and technology with an emphasis on advocacy and equity 7:00 Systemic issues that are easily overlooked in medical research and advancements Webinar: Participant Diversity: Increasing the Impact of Biomedical Research Webinar 10:00 Addressing Eurocentrici…
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So much is happening the world. At times, it feels confusing, frustrating, and a bit dis-orienting. It’s so helpful to look at the world through the lens of Biblical truth. God gives grace, peace, and the ability to be a positive influence on the issues that are trending now.
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The message of Jesus is not about being perfect, but about being changed by grace. Part two of our “My Story” series shows us that we follow a personal God who is loving us and pouring His grace into us in a personal way.By Jeff Leake
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EP 136: Developments in ring chromosome 20 research and advocacy with Allison Watson
40:57
40:57
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0:00 Introduction 2:00 Allison’s personal journey to researching epilepsy and ring chromosome 20 syndrome 4:00 Biggest challenges families face with ring chromosome 20 syndrome 11:00 Incidence and prevalence of r(20) syndrome, and how we can improve data reliability 21:00 Applying next generation sequencing to r(20) syndrome gene research 29:00 Eng…
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Have you ever wondered what God wants you to do with your life? Pastor Jeff shares a message about the assignments that God has for us.By Jeff Leake
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EP 135: Integration of newborn sequencing programs into healthcare systems with Dr. Ingrid Holm
41:16
41:16
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0:00 Introduction 1:30 Ingrid’s initial interests in genetics, paediatrics, and newborn screening 2:45 How the original BabySeq project, a pioneering newborn sequencing program got started, how it’s going, and the launch of BabySeq2 8:45 Lessons from BabySeq1 and goals for BabySeq2 10:30 Potential societal and long-term considerations for those inv…
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Removing Toxicity - Building a Culture of Honor
29:01
29:01
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Pastor Melodie Leakes shares a special Mother's Day message. This message explores what it means to honor others and to honor God.By Melodie Leake
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EP 134: Prenatal genetic testing and the future of AI in genetic counselling with Kira Dineen, host of DNA Today
40:44
40:44
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0:00 Introduction 1:00 The backstory of how Kira first started DNA Today in 2012, when she was still in high school! 3:30 Some of Kira’s favourite topics she has discussed on DNA Today, including the legacy of Henrietta Lacks, and the story of a Glee actress with down syndrome 10:00 Kira’s best practices for podcasting, from over 10 years of experi…
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What if your relationship problems require more than just strategic solutions, but spiritual ones? Pastor Jeff shares how to tap into supernatural solutions for the relational issues in our lives.By Jeff Leake
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EP 133: Insights into pharmacogenomics and increasing diversity in genomics research with Dr. Emma Magavern
39:17
39:17
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0:00 Introduction 2:00 The value of an English Literature degree in designing and analysing research studies in medicine 3:45 Emma’s entrance to pharmacogenomics and her transition from practising physician to genetics research 6:00 How the East London Genes and Health program is increasing representation of diverse populations, namely South Asians…
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Lifting Pressure - Living Financially Free
31:38
31:38
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Finances can be a major source of conflict for couples and families. Learn what the Bible has to say about dealing with relational issues and finding financial freedom.By Jeff Leake
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EP 132: From mammoths to genome editing, trailblazing genetics with Dr. George Church
47:41
47:41
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0:00 Introduction 1:00 George’s upcoming big projects, including developing full recycling, renewing energy, creating bioweather maps, and harnessing citizen science 6:45 Progress in engineering viral resistance in humans, including thoughts from pre- and post- pandemic 11:00 A swapped genetic code that prevents viral infections and gene transfer b…
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Navigating Conflict - Establishing Agreement
27:51
27:51
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By Jeff Leake
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EP 131: The potential of somatic genomics in drug discovery and development with Jake Rubens
44:57
44:57
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0:00 Intro 0:40 Jake’s experiences as a serial entrepreneur starting five companies with a basis in genomic science 5:30 Opportunities for research and drug development in the realm of somatic science 9:20 Somatic evolution and how it provides valuable insights into disease mechanisms 12:30 Advantages and disadvantages of studying germline genome-w…
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Do you want to have peace in your relationships and in your household? Pastor Jeff teaches on seven steps that you can take to bring peace and resolution to a conflict.By Jeff Leake
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EP 130: Quarterly insights into noncoding variants and GWAS with Dr. Veera Rajagopal
51:56
51:56
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Show Notes: 0:00 Introduction 1:20 How polydactyl mutations can inform research on non-coding variant mechanisms The importance of low-affinity binding between transcription factors and targets How these lessons can help us improve our understanding of drug and target discovery See Veera’s January round-up for more information: https://www.gwasstor…
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EP 129: Patient advocacy for genetic ALS and FTD with Jean Swidler, Executive Director of End the Legacy
38:44
38:44
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0:00 Introduction 0:45 Jean’s personal experiences with family members with genetic ALS 10:00 Jean’s thoughts on the barriers and facilitators to providing treatment for those with genetic ALS 13:20 Insights into C9orf72, a common genetic determinant of ALS, and how it can also be associated with FTD 16:10 Jean’s experiences as an active advocate f…
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Pastor Jeff shares a special Easter message about the greatest event in human history! During this message, we learn more about the resurrection of Jesus and who he is.By Jeff Leake
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EP 128: Parkinson’s disease and precision medicine with Drs. James Beck and Ignacio Mata
50:18
50:18
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0:00 Introduction 1:05 Insights into the PD GENEration’s (a programme from the Parkinson's Foundation) milestones and progress points for the upcoming year 3:30 The shifting attitudes and perspectives of neurologists and healthcare workers at the PD GENEration 5:50 Insights into Nacho’s work with the genetics of Parkinson’s disease 10:20 Barriers a…
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Jesus was a king, but what type of king? Pastor Josh Leake shares a message exploring Jesus' identity as king.By Josh Leake
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EP 127: Insights into precision medicine, fatty liver disease, and minimally invasive diagnostic tools with Dr. Mazen Noureddin
39:10
39:10
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0:00 Intro 0:25 Mazen’s lifelong commitment to furthering the field of precision medicine in liver disease research, fueled by a personal connection of his grandmother developing MASH cirrhosis 2:30 Breakthroughs in the field of metabolic dysfunction-associated steatotic liver disease (MASLD) since the beginning of Mazen’s career 5:30 The potential…
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Do you ever feel like a nobody? The good news is that through our relationship with Jesus we are elevated and get the same rights as him.By Jeff Leake
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EP 126: Patient-led research for ultra-rare disease drug development with Julia Taravella, Executive Director of Rare Trait Hope Fund
39:41
39:41
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0:00 Introduction 0:25 Julia’s personal experience with ultra-rare diseases within her family 10:25 The importance of increasing accessibility to genetic testing across populations to learn more about ultra-rare diseases 14:00 The origin story of Rare Trait Hope Fund 23:50 Current research and next steps in developing potential gene therapies for a…
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During this message we'll learn how the new covenant is now our inheritance. The book of Hebrews teaches us that the new covenant is a superior covenant, based on better promises.By Jeff Leake
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EP 125: The future of UK Clinical Trial Policy: Innovation, integration, and game-changing legislation with Lord James O’Shaughnessy
45:23
45:23
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0:00 Introduction 1:25 How Lord O’Shaughnessy became involved in scientific policy making and his path to writing the UK Commercial Clinical Trials Review. 04:05 How Lord O’Shaughnessy pivoted from education to a focus on life sciences 06:38 The biggest challenges Lord O’Shaughnessy faced during his time as Parliamentary Under Secretary for Health …
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In this next message in THE FINE PRINT series, we explore what our responsibility is in our covenant with God. We'll also see how the covenant is designed to impact nations and generations to come.By Jeff Leake
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EP 124: How ReCode Therapeutics is pioneering tissue specific delivery of gene therapies for Primary Ciliary Dyskinesia with John Matthews
42:00
42:00
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0:00 Introduction 01:10 How growing up in Malawi planted the seeds for John’s career in medicine and transition to therapeutic development 04:35 Why John focuses on rare diseases and conditions such as asthma 06:01 What has changed over the last decade in terms of treating and understanding asthma and the progress that genetics has enabled 07:31 Wh…
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Celebrating the new Creative and Professional Writing degree at the University of Waterloo
38:39
38:39
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Host Danielle Deveau interviews Antonio Michael Downing, Lamees Al Ethari, and Sarah Tolmie about the new Creative and Professional Writing degree program in the Department of English Language and Literature at the University of Waterloo.By Midtown Radio
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EP 123: The ethics of newborn genome screening: Actionable insights and beyond with Holly Peay, Senior Research Scientist at the Research Triangle Institute
45:34
45:34
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0:00 Introduction 0:50 Holly’s background and career so far 03:30 Complex decision-making and multiple risk factors: Family history, genetics, phenotypes and beyond 07:05 Changes within the last decade to help people make complex, sometimes subjective, healthcare decisions 09:20 Impact on people: The RTI’s mission and the Early Check Study 13:45 Ne…
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Pastor Melodie teaches on the covenant that God made with Abraham in Genesis. Through this, we learn about the covenant God has made with us and what we need to do to activate that promise.By Melodie Leake
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EP 122: Building genome-scale engineered cells for biotechnology with Leslie Mitchell, Co-founder and CEO of Neochromosome
35:55
35:55
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Summary: 0:00 Introduction 01:01 How Leslie got into the field of synthetic biology and engineering, and her career journey so far 02:45 What Leslie accomplished during her postdoc and recent transformations in the field of genomics 05:57 The impacts of non-coding regions of the genome and the outcome of deletions 08:20 How long it takes to make ch…
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During this message, Pastor Jeff teaches on biblical covenants, exploring why people made covenants and what were the benefits. This applies to our lives today because God made a covenant with us!By Jeff Leake
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EP 121: Breakthroughs and insights in ALS research with Dr. Michael Benatar
44:10
44:10
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Summary: 0:00 Introduction 0:50 Reflections from the 34th International Symposium on ALS/MND in Basel 1:50 Michael’s professional journey, initial challenges he encountered, and how the field of neurology has evolved over the years 3:10 An introduction to the ALS landscape, including its presentation, the genes involved, and potential treatment opt…
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Pastor Jeff starts a brand new series, entitled THE FINE PRINT, with a powerful message about the covenant relationship we have with God. Discover what promises God has made to you.By Jeff Leake
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EP 120: Exploring the frontiers of gene therapy and AAVs with Dr. Nicole Paulk, CEO and Founder of Siren Biotechnology
43:47
43:47
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0:00 Introduction to Dr. Nicole Paulk, a pioneer in AAV research and the founder of Siren Biotechnology 0:50 The moments that shaped Nicole’s career path and her passion for gene therapy and AAV research 9:20 Nicole’s academic research career and her transition from academia to the biotech industry 23:00 The story behind the founding of Siren Biote…
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Special guest evangelist Johannes Amritzer shares a message about the story of Rahab. Be encouraged by this powerful, redemptive story from the Bible.By Johannes Amritzer
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EP 119: Revolutionising drug discovery: how the Pharma Proteomics Project is combining genetic and proteomic data with Chris Whelan
38:25
38:25
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0:00 Introduction 01:00 Chris’ background and career to date 02:10 What is the Enigma Project? 04:48 How is genetics being applied to drug discovery today and how does proteomics fit in? 09:23 When the UKBiobank Pharma Proteomics Project began and how long it took to set up 10:57 54k UK Biobank participants tested - discussion of findings 14:33 The…
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What if all the noise, all the media, all the advertisements we encounter on a daily basis are keeping us from connecting with God? Pastor Josh Leake shares a message about the importance of withdrawing and connecting with the Creator.By Josh Leake
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EP 118: The role of genetics in drug discovery and development with Dr. Matt Nelson
42:56
42:56
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Summary: 0:00 Introduction 5:45 Lessons learned from 15 years at GSK: How has genetics and drug discovery evolved over time? 8:10 Matt’s seminal 2015 paper: Quantifying the impact of human genetic evidence on the probability of success in drug development 11:40 Which types of genetic evidence are the best drivers of success in clinical trials? 13:3…
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The desire for possessions or accomplishments fuels our hurried lifestyles but doesn't lead to fulfillment. In this message, learn three truths to help you prioritize what really matters.By Jeff Leake
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EP 117: Wendy Chung: whole genome newborn screening and other big opportunities in genomic medicine.
47:51
47:51
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Summary: 0:00 Introduction 1:45 Wendy’s early career looking into the genetics of diabetes through mouse models 6:23 A high altitude view: Cutting through hype to spot the next wave of game-changing technology 8:03 The role of policy and communication: how Wendy’s work goes beyond the lab to create real-world impact 11:20 Wendy’s choice to do an MD…
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How can you gain the ability to do what really matters calmly and with joy? In this message, Pastor Jeff gives us three questions to ask as we seek to eliminate hurry from our lives.By Jeff Leake
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EP 116: Genetics and Medicine: Clonal hematopoiesis, genomics in healthcare, and a new discovery in APOL1 kidney disease with Dr. Alex Bick
52:34
52:34
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0:00 Introduction 4:23 Insights into clonal hematopoiesis from the pioneering Framingham Heart Study 8:30 Linking clonal hematopoiesis to cancer and cardiovascular health 11:22 Interplay of germline and somatic variants in clonal expansion 17:20 How the rate of clonal expansion can provide insights into cancer and cardiovascular risk 19:00 How clon…
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Do you have "hurry sickness"? Always feel like you're in a rush? In this message, you'll learn how soul health requires a commitment to the rhythm of rest.By Jeff Leake
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