The a16z Podcast discusses tech and culture trends, news, and the future – especially as ‘software eats the world’. It features industry experts, business leaders, and other interesting thinkers and voices from around the world. This podcast is produced by Andreessen Horowitz (aka “a16z”), a Silicon Valley-based venture capital firm. Multiple episodes are released every week; visit a16z.com for more details and to sign up for our newsletters and other content as well!
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Andreessen Horowitz ("a16z") co-founders Marc Andreessen and Ben Horowitz explore everything from science to business to culture, all through the lens of technology.
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"web3 with a16z" is a show about the next generation of the internet, and about how builders and users -- whether artists, coders, creators, developers, companies, organizations, or communities -- now have the ability to not just "read" (web1) + "write" (web2) but "own" (web3) pieces of the internet, unlocking a new wave of creativity and entrepreneurship. Brought to you by a16z crypto, this show is the definitive resource for understanding and going deeper on all things crypto and web3. Fro ...
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a16z Live is the place to listen to recorded live discussions and events featuring, hosted, or co-hosted by a16z partners (with outside voices too). As a reminder, all content posted here is provided for informational purposes only, and should not be relied upon as legal, business, investment, or tax advice. Views expressed are those of the individuals and not the views of Andreessen Horowitz, please see a16z.com/disclosures for more. To learn more about the broader a16z Podcast network and ...
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A myriad of AI, science, and technology experts explore the real challenges and enormous opportunities facing entrepreneurs who are building the future of health. Raising Health, a podcast by a16z Bio + Health and hosted by Kris Tatiossian and Olivia Webb, dives deep into the heart of biotechnology and healthcare innovation. Join veteran company builders, operators, and investors Vijay Pande, Julie Yoo, Vineeta Agarwala, and Jorge Conde, along with distinguished guests like Mark Cuban, Greg ...
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Join writer and storyteller Damien Walter on an exploration of the world as seen through a science fiction lens.
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Most business podcasts follow a similar format: find a successful CEO and have them tell their story. This is not that show. Zero to IPO tackles real world problems with real world experience, featuring actionable advice and anecdotes from some of the world's most innovative founders. In season one, we broke down each stage of a company's growth cycle on a granular level with everyone from Parker Harris of Salesforce.com, to Julia Hartz of Eventbrite and Marc Andreessen of Andreessen Horowit ...
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From 2024 on we'll be bringing you monthly long-form interviews with the biggest names in European startups. We'll hear from the founders, operators and investors behind the continent's biggest tech companies, to learn what makes them tick and what they've learnt as they've built their businesses.
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16 Minutes on the News is a short news podcast where we cover the top headlines of the week, the a16z podcast way -- why are these topics in the news; what's real, what's hype from our vantage point; and what are our experts' quick takes on these trends? About the a16z Podcast: Discusses tech and culture trends, news, and the future -- especially as ‘software eats the world’. It features industry experts, business leaders, and other interesting thinkers and voices from around the world. This ...
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Finance & Culture aims to elevate listener's financial literacy by informing, inspiring, and empowering them to prosper, thus yielding long-term success.
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Across The Lines is a podcast that highlights the stories of Pan Asian American leaders and explores the intersection of their personal and professional journeys. Our vision is to inspire and empower the next generation of leaders through candid conversations about the confluence of identity and work.
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How to Start a Startup
Y Combinator and Stanford University: Sam Altman, Dustin Moskovitz, Paul Graham, Adora Cheung, Peter Thiel, Alex Schultz, Kevin Hale, Marc Andreessen, Ron Conway, Ben Silbermann, Alfred Lin, Patrick and John Collison, Aaron Levie, Reid Hoffman & more
Sam Altman and the folks from Y Combinator offer up an amazing course in "How To Start A Startup" at Stanford. Course includes lectures from: Sam Altman, Dustin Moskovitz, Paul Graham, Adora Cheung, Peter Thiel, Alex Schultz, Kevin Hale, Marc Andreessen, Ron Conway, Ben Silbermann, Alfred Lin, Patrick and John Collison, Aaron Levie, Reid Hoffman, Keith Rabois, Ben Horowitz, Marissa Mayer, Hosian Rahman, Kirsty Nathoo, Carolynn Levy, and more
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Latin America is emerging as a tech powerhouse, but it's not a one-size-fits-all market. In this episode, we explore why what works in Argentina won’t necessarily fly in Brazil or Mexico, and how companies are adapting to these unique regional dynamics. Join Dileep Thazhmon, Cofounder and CEO of Jeeves; Santiago Suarez, Cofounder and CEO of Addi; G…
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Programmable plants and neurotech devices: Inside the UK government’s £800m “inventions” agency
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This month we’re joined by Ilan Gur, CEO of the UK’s Advanced Research and Invention Agency (or ARIA), a government body set up last year to fund ambitious, breakthrough innovations. Before joining Aria, Gur was a programme director at ARPA-E, the US government’s Advanced Research Projects Agency, which was established to develop new cutting-edge t…
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In the Vault: AI and Banking Innovation with Tim Karpoff of Citi
24:12
24:12
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a16z general partner David Haber and fintech partner Marc Andrusko talk to Tim Karpoff, the Global Head of Strategy at Citi, where he guides the bank’s core focus areas, as well as future investment in emerging tech like AI. The conversation covers the shifting landscape of banking policy and regulation, the increasingly important role startups are…
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Harnessing Water Dynamics for Drug Design with Michael Crackower and Jason Burch
37:24
37:24
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Michael Crackower, PhD, Chief Scientific Officer of Ventus Therapeutics, and Jason Burch, PhD, join Vineeta Agarwala, MD, PhD, general partner at a16z Bio + Health. Together, they talk about how Ventus approaches drug discovery and why they believe we’re in the early stages of small molecule innovation. Specifically, we’ll hear about the ReSOLVE pl…
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In this episode, we cover the recent data breach of nearly 3B records, including a significant number of social security numbers. Joining us to discuss are security experts Joel de la Garza and Naftali Harris. Incredibly enough, Naftali and his team were able to get their hands on the breached dataset and were able to validate the nature of the cla…
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with @ahall_research @eddylazzarin @0xShuel @smc90 In this episode, we cover both recent events + evergreen governance questions in political systems: Specifically, we breakdown the recent Compound “governance attack”... as well as the broader topic of DAO governance and voting in general. We also discuss how to avoid, prevent, and respond to such …
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Building Innovation Hubs: The UK & Beyond
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45:44
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This episode from Web3 with a16z Crypto, is all about innovation on a global scale, exploring both ecosystem and individual talent levels. We examine what works and what doesn’t, how certain regions evolve into startup hubs and economic powerhouses, and what constitutes entrepreneurial talent. We also discuss the nature of ambition, the journey to …
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Building the World’s Most Trusted Driver with Waymo's Dmitri Dolgov
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Waymo co-CEO Dmitri Dolgov joined a16z general partner David George to discuss how Waymo is using genAI to help them build safer, sustainable, and more accessible transportation. In the conversation, Dmitri talks about the potential of embodied AI, the value of simulations and building training data, and his approach to leading a company focused on…
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AI at the Intersection of Bio with Vijay Pande, Surya Ganguli, and Bowen Liu
30:08
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Bowen Liu, PhD, investing partner, and Surya Ganguli, PhD, venture partner, join Vijay Pande, PhD, general partner of a16z Bio + Health. Together, they detail different methods through which AI could assist drug development, the opportunity for AI to flag new targets and compounds for scientists to investigate, and the science fiction-sounding noti…
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The Olympics of Talent: France's Tech Boom
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Once criticized for lacking ambition, French founders are now aiming to create the world’s largest companies. With a thriving ecosystem attracting talent from across Europe and the US, France is becoming a major player on the global stage. In this episode, we cover the unique advantages of building startups in France. Roxanne Varza, Director of Sta…
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with @eddylazzarin @milesjennings @rhhackett Today’s episode covers all things tokens — that includes what tokens have to do with decentralized protocols, understanding the different types of tokens, and, of course, the Do's and Don'ts of designing and launching a token. Our guests are a16z crypto chief technology officer Eddy Lazzarin, as well as …
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Bringing Production-Ready GenAI to the Enterprise
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As genAI expands through the enterprise, many leaders are figuring out how to evolve their genAI prototypes into production-ready tools. Pinecone CEO Edo Liberty and LangChain CEO Harrison Chase discuss which parts of the stack to build or buy, how to improve out-of-the-box models by helping customers select and ingest the right data, and picking t…
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The History and Future of CAR T with Bruce Levine
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Bruce Levine, PhD, the Barbara and Edward Netter Professor in Cancer Gene Therapy at the University of Pennsylvania, joins Jorge Conde, general partner, and Ginger Liau, partner at a16z Bio + Health. Bruce talks about how his time working in a lab at the Children’s Hospital of Philadelphia inspired him to work on translational therapies. Together, …
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Waymo's autonomous vehicles have driven over 20 million miles on public roads and billions more in simulation. In this episode, a16z General Partner David George sits down with Dmitri Dolgov, CTO at Waymo, to discuss the development of self-driving technology. Dmitri provides technical insights into the evolution of hardware and software, the impac…
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From AI to Instant Replay: The Technology Behind the Olympics
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36:29
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The Olympics features over 11,000 athletes competing in 32 sports, attracting an audience of more than 10 million. In this episode, Charlie Ebersol, co-founder of the Alliance of American Football and Infinite Athlete, explores how new innovations like AI and bespoke broadcasting technologies are shaping the future of sports. Charlie also reflects …
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with @matthewclifford @smc90 This special episode is all about regional innovation — at both a systems and people level. We cover what does and doesn’t work in making certain places become hubs of innovation and economic growth (aka “innovation ecosystems”). But we also discuss — going back and forth between the structural and individual — when to …
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On June 27th, the a16z team headed to New York City for the first-ever AI Artist Retreat at their office. This event brought together the builders behind some of the most popular AI creative tools, along with 16 artists, filmmakers, and designers who are exploring the capabilities of AI in their work. In this episode, we hear from the innovators pu…
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Implementation, Data, Impact of Healthcare AI with Vijay Pande and Julie Yoo
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In this episode, a follow-up to our episode Grand Challenges in Healthcare AI, Julie Yoo and Vijay Pande, a16z general partners, answer audience questions about AI applications in healthcare. Together, they dive into cost and implementation challenges, the data landscape, and what the patient experience might look like. If you liked this episode, l…
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Climate tech’s growing pains with Pale Blue Dot’s Heidi Lindvall
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She’s one of the three founders of Pale Blue Dot, a Malmö-based early-stage climate tech fund which launched in 2020 and backs pre-seed and seed-stage startups reducing and reversing the effects of climate change, in Europe and the US. Pale Blue Dot came along just ahead of the wave of climate tech funds which launched in Europe amid the tech boom.…
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Founders Playbook: Lessons from Riot, Discord, & More
25:56
25:56
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Gaming is not just entertainment—it's a revolution reshaping our culture, technology, and economy. a16z’s Jonathan Lai and Andrew Chen dive into the current gaming renaissance and its future impact. Joining them are Michael Chow, CEO and Steven Snow, CPO of The Believer Company, and Eros Resmini, Founder and Managing Partner of The Mini Fund. They …
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In the Vault: Public Market and Macro Perspectives with Mark Casey of Capital Group
26:05
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In this episode, which took place at a16z's Connect Fintech event, a16z General Partner David George interviews Capital Group's Mark Casey on his investment philosophy, what sends him into what he calls "barnacle mode," his preference for customer-focused North Star metrics, and more. 0:00-1:42 Intro 1:42-5:58 Approach to investing 5:58-8:20 What C…
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Protecting the Golden Age of Medicine with John Crowley
30:33
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John Crowley, President and CEO of Biotechnology Innovation Organization (BIO), joined Jorge Conde, general partner at a16z Bio + Health. Together, they talk about John’s entry into biotech and his time as a founder, all motivated by his determination to discover and develop a treatment for his children, who have Pompe disease. They also talk about…
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with @rhhackett @smc90 @stephbzinn @tim_org In this fun hallway-style conversation, a16z crypto's Sonal Chokshi, Robert Hackett, Tim Sullivan, and Stephanie Zinn discusses picks from our latest annual summer reading list, as well as evergreen/ Lindy picks that show up on our what-we're-reading lists again and again. We also share our top picks of a…
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SF author Ken MacLeod on his lifelong friend Iain Banks.Become a member of the Science Fiction community to continue the discussionWebsite - https://damiengwalter.comYouTube - https://www.youtube.com/c/DamienWalter/membershipPatreon - https://www.patreon.com/DamienWalterSubscribe to the Science Fiction podcast feed for long-form commentaries on the…
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Transitioning From Gymnast to Investor with Aly Raisman
21:39
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Former gymnast and current investor Aly Raisman joins general partner Julie Yoo and investment partner Daisy Wolf of a16z Bio + Health. In this episode, Aly Raisman shares her quest for healthier living—physically, mentally, and financially—on her journey from gymnast to a business investor. Having transitioned from an intensely structured routine,…
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The Little Tech Agenda: Biden vs. Trump
1:25:14
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Welcome to "The Ben & Marc Show," featuring a16z co-founders Marc Andreessen and Ben Horowitz. In this new episode, Marc and Ben discuss their latest article, “The Little Tech Agenda,” and why the future of American innovation is at a critical juncture. In a one-on-one conversation, Ben and Marc compare the policies of Donald Trump and Joe Biden re…
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A Fatal Inheritance with Lawrence Ingrassia
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28:05
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Lawrence Ingrassia, author and journalist, joins Vineeta Agarwala, general partner, and Kris Tatiossian, editorial lead at a16z Bio + Health. Together, they discuss Larry's recently published book, A Fatal Inheritance: How A Family Misfortune Revealed A Deadly Medical Mystery. In the book, Larry recounts the story of the p53 cancer suppressor gene,…
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Live at Tech Week: Delivering AI Products to Millions
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Less than two years since the breakthrough of text-based AI, we now see incredible developments in multimodal AI models and their impact on millions of users. As part of New York Tech Week, we brought together a live audience and three leaders from standout companies delivering AI-driven products to millions. Gaurav Misra, Cofounder and CEO of Capt…
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Network Medicine with Jonathan Swerdlin and Mark Hyman
33:14
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Jonathan Swerdlin, cofounder and CEO, and Mark Hyman, MD, cofounder and Chief Medical Officer of Function Health join Vijay Pande, general partner, and Daisy Wolf, investment partner of a16z Bio + Health. Together, they discuss their personal health journeys that led to founding Function, how they’re planning to scale Function, and what the future …
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Marc Andreessen on Building Netscape & the Birth of the Browser
1:42:50
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"The Ben & Marc Show," featuring a16z co-founders Marc Andreessen and Ben Horowitz. In this special episode, Marc and Ben dive deep into the REAL story behind the creation of Netscape—a web browser co-created by Marc that revolutionized the internet and changed the world. As Ben notes at the top, until today, this story has never been fully told ei…
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The Art of Technology, The Technology of Art
1:03:49
1:03:49
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We know that technology has changed art, and that artists have evolved with every new technology — it’s a tale as old as humanity, moving from cave paintings to computers. Underlying these movements are endless debates around inventing versus remixing; between commercialism and art; between mainstream canon and fringe art; whether we’re living in a…
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Marc Andreessen on Building Netscape & the Birth of the Browser
1:44:56
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Welcome back to "The Ben & Marc Show," featuring a16z co-founders Marc Andreessen and Ben Horowitz. In this special episode, Marc and Ben dive deep into the REAL story behind the creation of Netscape—a web browser co-created by Marc that revolutionized the internet and changed the world. As Ben notes at the top, until today, this story has never be…
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DeepL founder Jarek Kutylowski on how his AI startup took on Google Translate — and won
32:10
32:10
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This week on the pod we’re joined by Jarek Kutylowski, founder and CEO of German AI startup DeepL. He’s built a profitable business in a field where he’s had to compete with the likes of Google, by developing cutting edge language translation technology. The company says it now has “a customer network of 100k+ businesses, governments and other orga…
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Cybersecurity's Past, Present, and AI-Driven Future
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Is it time to hand over cybersecurity to machines amidst the exponential rise in cyber threats and breaches? We trace the evolution of cybersecurity from minimal measures in 1995 to today's overwhelmed DevSecOps. Travis McPeak, CEO and Co-founder of Resourcely, kicks off our discussion by discussing the historical shifts in the industry. Kevin Tian…
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On Finding Product Market Fit — and Meaning
1:05:51
1:05:51
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with @jasonrosenthal @benrbn Welcome to web3 with a16z, a show about building the next generation of the internet. Our featured guest today is serial entrepreneur Ben Rubin, who previously built the viral livestreaming app Meerkat, and then the group video chat app Houseparty — acquired by Epic Games in 2019 — and who is now CEO and cofounder of He…
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Regulation as a Catalyst with Jonathan Bush and Chris Severn
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37:08
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Jonathan Bush, founder and CEO of Zus Health, and Chris Severn, cofounder and CEO of Turquoise Health, join Julie Yoo, general partner, and Colin Rom, head of public policy for a16z Bio + Health. We’ve long believed that regulatory change can be a catalyst for company creation. In this episode, Jonathan and Chris detail how that was true for them. …
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In the Vault: New Applications in Fintech with Plaid’s Zach Perret and Marqeta’s Simon Khalaf
24:43
24:43
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In this conversation, which took place at a16z's Connect Fintech event, a16z General Partner Angela Strange, Plaid CEO and cofounder Zach Perret, and Marqeta CEO Simon Khalaf discuss how AI will shape the future of banking, the battle between payment rails in the U. S., and how there's still opportunity to transform the basic credit card into a ful…
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Brooke Boyarsky Pratt, founder and CEO of knownwell, joins Vineeta Agarwala, general partner at a16z Bio + Health. Together, they talk about the value of obesity medicine practitioners, patient-centric medical homes, and how Brooke believes the metabolic health space will evolve over time. This is the second episode in Raising Health’s series on th…
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The Transformative Power of AI in Science with Pushmeet Kohli
56:25
56:25
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In this episode, originally recorded for the a16z Podcast, host Steph Smith interviews Pushmeet Kohli, DeepMind's VP of Research focused on AI for science. They are joined by a16z Bio + Health founding partner Vijay Pande. Together, they discuss AI at scale, and its power to transform science.By Steph Smith, Pushmeet Kohli, Olivia Webb, Vijay Pande, Kris Tatiossian
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Governing democracy, the internet, and boardrooms
1:35:40
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with @NoahRFeldman, @ahall_research, @rhhackett Welcome to web3 with a16z. I'm Robert Hackett and today we have a special episode about governance in many forms — from nation states to corporate boards to internet services and beyond. Our special guests are Noah Feldman, constitutional law scholar at Harvard who also architected the Meta oversight …
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In this latest episode on the State of AI, Ben and Marc discuss how small AI startups can compete with Big Tech’s massive compute and data scale advantages, reveal why data is overrated as a sellable asset, and unpack all the ways the AI boom compares to the internet boom. Subscribe to the Ben & Marc podcast: https://link.chtbl.com/benandmarc Stay …
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The Science and Supply of GLP-1s with Chronis Manolis
31:30
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Chronis Manolis, SVP and Chief Pharmacy Officer of UPMC Health Plan, joins Julie Yoo, general partner, Daisy Wolf, investment partner, and Will Shrank, venture partner, of a16z Bio + Health. Together, they discuss how payors and providers are thinking about anti-obesity medications, as well as pricing and prior authorization considerations. This is…
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Predicting Revenue in Usage-based Pricing
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Over the past decade, usage-based pricing has soared in popularity. Why? Because it aligns cost with value, letting customers pay only for what they use. But, that flexibility is not without issues - especially when it comes to predicting revenue. Fortunately, with the right process and infrastructure, your usage-based revenue can become more predi…
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California's Senate Bill 1047: What You Need to Know
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On May 21, the California Senate passed bill 1047. This bill – which sets out to regulate AI at the model level – wasn’t garnering much attention, until it slid through an overwhelming bipartisan vote of 32 to 1 and is now queued for an assembly vote in August that would cement it into law. In this episode, a16z General Partner Anjney Midha and Ven…
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The Science and Supply of GLP-1s with Brooke Boyarsky Pratt
42:53
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Brooke Boyarsky Pratt, founder and CEO of knownwell, joins Vineeta Agarwala, general partner at a16z Bio + Health. Together, they talk about the value of obesity medicine practitioners, patient-centric medical homes, and how Brooke believes the metabolic health space will evolve over time. This is the second episode in our series on the science and…
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with @jasonrosenthal @skominers @meigga @rhhackett Welcome to web3 with a16z, I’m Robert Hackett and today, we discuss pricing strategy for startups — from traditional businesses to web2 to web3. Topics we cover include: unit economics understanding consumer psychology using onchain data to inform pricing decisions Common mistakes and how to avoid …
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The Science and Supply of GLP-1s with Carolyn Jasik
29:42
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Carolyn Jasik, MD, Chief Medical Officer of Omada Health, joins Vijay Pande, founding partner of a16z Bio + Health. As Ozempic, Wegovy, Mounjaro, and Zepbound capture the healthcare spotlight, we’ve developed a series of episodes that go beyond the headlines and take you into conversations with the specialists. Our first guest is Carolyn Jasik, Chi…
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Consumer AI is moving fast, so who's leading the charge? a16z Consumer Partners Olivia Moore and Bryan Kim discuss our GenAI 100 list and what it takes for an AI model to stand out and dominate the market. They discuss how these cutting-edge apps are connecting with their users and debate whether traditional strategies like paid acquisition and net…
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Index Ventures partner Martin Mignot on where Revolut should list
47:19
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Name a big European tech company, and there’s a high chance Martin Mignot, partner at Index Ventures, invested in it. Martin’s portfolio includes some of the continent’s big winners, like car sharing platform BlaBlaCar, digital bank Revolut, digital health provider Kry, HR platform Personio and delivery company Deliveroo — and some of its big failu…
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Open Sourcing the Superchain (with Optimism)
1:25:59
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with @jinglejamOP @eddylazzarin @rhhackett Hello and welcome to web3 with a16z, a show about building the next era of the internet by the team at a16z crypto, that includes me, host Robert Hackett. Today’s episode features Jing Wang, CEO and executive director of the Optimism Foundation, along with a16z crypto CTO Eddy Lazzarin. We discuss the pecu…
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