Behind the Biochemistry is YOUR go-to podcast to engage with your inner scientific curiousty! On this podcast we will bust out the beakers to dive into the depths of topics such as cellular pathways that are essential to our daily lives & what happens when these are influenced via a variety of factors. We will include special guests and go and visit researchers and scientific entrepreneurs. It's time to have some fun, bust out the beakers, and find out what it BEHIND THE BIOCHEMISTRY!
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Medicinal Chemistry Masters graduate, part-time nutritionist & full-time foodie. Join me and BioChemistry PhD Piotr Manasterski as we delve into the proven and zero-nonsense science behind nutrition.
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Join Dr. Robert Pastore and his co-host Lexie (@lexircise) as they discuss and clarify nutritional and neurochemical science. Dr. Pastore is also joined by guests from backgrounds of all types – from all-star athletes, to top trainers and coaches, to scientists and researchers - and dives deeply into the science behind optimizing performance and longevity. Dr. Pastore is a Certified Nutrition Specialist, and holds an MS in Human Nutrition from Eastern Michigan University and a Ph.D. in Biome ...
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Pretty Fly for 2 Sci Guys #13 - Stress 101: Breath Work, CBT & Mindset
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27:20
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A deep dive on mindset as Piotr and Dec are back!We share our best tips on destressing, the science behind emotions and how to tackle negative thoughts or behaviours.By Dec McLaughlin Nutrition
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Dr. Pastore discusses the role hormones play when it comes to food allergies and food-mediated reactions. High estrogen can cause worsened food allergy symptoms. Show notes will be available Tuesday, August 4th at drrrobertpastore.com/podcastsBy Dr. Robert Pastore
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Pretty Fly for 2 Sci Guys Ep #12 w/ Craig McKenna - Kickboxing, Flow State & Exponential Growth
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Join us for a truly special episode as we welcome close friend and kickboxing expert Craig McKenna from Combat Solutions Edinburgh!We take a deep-dive on multi-skill based learning, why progress is painfully slow and letting go of your ego.By Dec McLaughlin Nutrition
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According to the American college of allergy, asthma and immunology, approximately 25 million Americans suffer from Seasonal allergic rhinoconjunctivitis. One in six Canadians suffers from seasonal allergic rhinitis (commonly known as hay fever). If you suffer from seasonal allergies or hay fever, there may be a connection to fruit and/or vegetable…
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Dr. Pastore discusses the top 9 food allergies, and a new consumer study showing that these allergy diagnoses are on the rise. Topics covered include what a food allergy is, when and why food allergies appear, anaphylaxis and less severe symptoms of a food allergy, and what to discuss with your doctor to get a formal diagnosis. Show notes: https://…
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Pretty Fly for 2 Sci Guys Ep #11 - Everything you need to know about fat loss
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Listen to our deep-dive on all things fat loss! The basics you need to know if you're getting started.Plus our favourite fat-loss strategies and why walking beats running.By Dec McLaughlin Nutrition
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Pretty Fly for 2 Sci Guys Ep #10 - Saunas, Cold Showers & Good Stress
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Join Dec and Piotr as we dive into the science behind 'hormesis'. We'll be sharing our best tips on how to add more stress into your life to grow in body and mind.By Dec McLaughlin Nutrition
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Dr. Pastore discusses a new, at-home test that celiacs can utilize to determine if they have been exposed to gluten, why it’s important to monitor gluten exposure, the shockingly high rates of unknown gluten exposure among celiacs following a gluten-free diet at home and in restaurants, and what the research has to say about the accuracy of the new…
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On Autoimmune Thyroid Diseases (& the Celiac Connection)
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Dr. Pastore covers the thyroid gland, non-autoimmune hypo & hyperthyroidism, the autoimmune thyroid diseases Hashimoto's Thyroiditis and Grave’s Disease, how the two are connected to celiac disease, and what tests you should request from your physician to be an advocate for your own health. SHOW NOTES: https://drrobertpastore.com/podcasts/068-thyro…
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On Celiac Disease & Cardiovascular Disease
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55:58
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Dr. Pastore discusses the connection between celiac disease and cardiovascular disease that many physicians miss when treating a patient with either. He covers how gluten consumption can affect the cardiovascular system, arteries, and veins; cause physical structure and electrical changes of the heart; and increase the risk of a heart attack. If yo…
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Pretty Fly for 2 Sci Guys Ep #9 - Sleep, Cocoa Powder & Alarm Clocks
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28:15
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Join Piotr and Dec as we do a deep dive on the science behind sleep and why it's so critical for performance, mood and productivity.Plus a handful of our best tips on how to optimise your sleep schedule and get the recovery you need!By Dec McLaughlin Nutrition
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On Persistent Organic Pollutants (& the Celiac Connection)
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Dr. Pastore discusses a new NYU study that monitored children’s exposure to persistent organic pollutants (POPs) - chemicals that have a long-lasting effect on the planet with the ability to accumulate in our ecosystem and bodies, such as DDT and PCB - and the connection to celiac disease. He covers where POPs are found, the risks of chronic POP ex…
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On Inflammatory Bowel Diseases (& the Celiac Connection)
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A new study released in May 2020 has revealed connections between inflammatory bowel diseases (IBD) and celiac disease. Before discussing study findings, Dr. Pastore first covers what IBD is, how it differs from irritable bowel syndrome (IBS), who is most at risk, the complications and treatment for IBD. SHOW NOTES: https://drrobertpastore.com/podc…
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Continuing with topics around Celiac Disease Awareness Month, Dr. Pastore discusses a condition that some diagnosed celiacs are still faced with - refractory celiac disease. He covers what it is, how it’s diagnosed, how common it is amongst diagnosed celiac disease patients, the signs and symptoms to look out for, causes, treatments, secondary food…
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Dr. Pastore covers a well-known, yet not well-understood diagnostic marker of celiac disease - tissue transglutaminase (TTG). He covers the function TTG plays as an enzyme, how TTG affects gluten and shares vital information about various TTG blood tests (TTG IgA and TTG IgG) for those looking for a diagnosis, and for the diagnosed celiac wanting t…
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May is Celiac Disease Awareness Month, and Dr. Pastore covers important and relevant information on all-things celiac disease including statistics, symptoms, the history of the disease and how to go about being diagnosed, as 83% of those with the disease are not. Show notes: https://drrobertpastore.com/podcasts/celiac-disease-awareness-month-2020…
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Ask Dr. Pastore: On Gut Health & Digestion
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Dr. Pastore answers questions asked by Lexie’s fitness training team around gut health, digestion, food intolerances, candida, h-pylori, probiotics, and gut microbiota. Show notes: https://drrobertpastore.com/podcastsBy Dr. Robert Pastore
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Dr. Pastore discusses the vital role sleep plays in immunity, how lack of sleep and poor quality sleep can lower your immune system, sleep duration guidelines for optimal health and steps you can take to improve your sleep. What is “poor” sleep [1:00] Quality sleep for adults 7-9 continuous, uninterrupted hours of sleep per night Likely not possibl…
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On New Acute Symptoms of Celiac Disease & Gluten Exposure for Celiacs
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32:28
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As covered in previous podcasts, celiac disease can have many symptoms beyond gastrointestinal issues and looking skinny/malnourished. In this episode, Dr. Pastore discusses a study that revealed two new acute, non-classic symptoms that could be the only sign of celiac disease - nausea and vomiting within 2-4 hours of eating. Both symptoms typicall…
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Dr. Pastore shares the science and latest research behind coronavirus, how it differs from COVID-19 and what makes it so dangerous. As he is actively treating those with the virus, he covers the lesser-known symptoms, the genetic polymorphisms (gene errors) that put some more at risk than others beyond age and pre-existing medical conditions, the c…
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[PART 2] Dr. Pastore continues on the topic of brain health, and what celiacs & non-celiacs can do now to lower the risk of future neurological & cognitive health issues. He covers what medical tests to have done, recommended foods and supplements, as well as ways to cognitively challenge your brain. Recap of part 1, upcoming in episode [0:40] Key …
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[PART 1] Dr. Pastore discusses the topic of mental health and celiac disease after the results of a brand new study that was released this week. Sometimes, mental illnesses, ataxia, multiple sclerosis, personality disorders can be the only sign or symptom of celiac disease. These can also be comorbidities of celiac disease (simultaneous presence of…
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Dr. Pastore discusses the dental defects he suffered with prior to his celiac diagnosis, and how gluten and oral health are connected. Discussed: - What causes dental enamel defects (DED) and demineralization - How DED is associated with celiac disease - One study found that 83% of celiac disease patients had some degree of DED - How other oral hea…
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Dr. Pastore discusses Dermatitis Herpetiformis - an autoimmune condition with skin rashes that is caused by the consumption of gluten. He covers who is most at risk, what this autoimmune condition is, how to get properly diagnosed and the celiac disease connection. Discussed: Dermatitis Herpetiformis (DH) is NOT the same as celiac disease. The majo…
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On Lactose Intolerance (& the Celiac Connection)
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Dr. Pastore dives into the prevalence of lactose intolerance in celiacs, and celiac disease in those with lactose intolerance. In this episode, he covers: -What a lactose intolerance is and how is it different from a milk/dairy allergy or sensitivity -68% of the adult population has a lactose intolerance, but who is most at-risk: https://ghr.nlm.ni…
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Dr. Pastore covers key information a newly diagnosed celiac patient should know, including: Why a biopsy is key for confirmed diagnosis You cannot outgrow this disease Why you should see a Registered Dietician or Certified Nutrition Specialist immediately after your physician’s diagnosis “Gluten free” foods & cross contamination How to tackle resta…
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In this episode Dr. Pastore covers: Infertility in men and women could be caused by Celiac Disease If you have the HLADQ2 or HLADQ8 Celiac gene but do not have Celiac disease, your child still could be born with or develop Celiac disease If one of the biological parents are a gene carrier or are a diagnosed Celiac, a gluten-free diet should be foll…
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In this episode, Dr. Pastore discusses: DAILY Nutrient Requirements for Pregnant Women: 1) Folate 1000 micrograms of L-methyl-folate per day, rather than folic acid MTHFR gene variance - affects folate utilization and can cause folic acid deficiency which can cause the infant to be born with spina bifida or cleft pallet 2) Iodine 250 micrograms per…
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The first 1000 days of life - from conception to age two - are the most CRITICAL nutritional period to prevent health issues and diseases that may arise later in a human’s life. Dr. Pastore shares his two+ decades of experience treating pregnant women and optimizing their nutrition for a safe, healthy pregnancy. Information discussed: Ask your doct…
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On "Calories In Calories Out" for Weight Loss
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Dr. Pastore and Lexie are back and kicking off 2020 with a popular “New Years Resolution” health topic - calories in vs. calories out. When it comes to weight loss, there are many factors people typically don’t take into consideration when calculating both the “calories in” and “calories out” portions of the equation. They discuss: What a calorie i…
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“If you hear hoofs coming behind you, don’t assume it’s a zebra” In this episode, Dr. Pastore shares one of his favorite patient cases where he was able to identify a “zebra” diagnosis when the medical community had diagnosed this patient with ALS (amyotrophic lateral sclerosis, also known as Lou Gehrig's disease) - a disease that gradually paralyz…
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This week we discuss being “punked” and what to do if you unknowingly (or willingly against all recommendations) ingest gluten as a celiac. Dr. Pastore shares his personal experience and discusses the typical symptoms a celiac would experience, the facts and myths about what a celiac should do to recover if they have consumed gluten, the immediate …
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In this conversation, Dr. Pastore explains the direct scientific links between gut health and mood. He covers how the gut and brain are systematically connected, the balance of gut microbiome, and why a damaged digestive tract can lead to mood-related disorders such as depression and anxiety.By Dr. Robert Pastore
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Dr. Pastore shares his history with migraines and the signs, symptoms, causes, treatments and science behind migraines. Talking points include: The 4 stages of the migraine, including the “migraine hangover” A sub-class of migraines called allodynia - the experience of pain from stimuli that isn't normally painful (ex - pain caused by steam/water f…
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On Nutritional Deficiencies and Increased Infection Risk for the Celiac Population
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54:25
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Dr. Pastore covers the typical nutritional deficiencies the newly diagnosed celiac patient may experience, the mistakes practitioners make when attempting to correct these deficiencies, and what YOU can do to be your own health-care advocate. He then explains why those with celiac diseases (following a gluten-free diet or not), or even those with a…
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(Part 2 of 2) Dr. Pastore and Lexie dive into what is happening to the brain chemically in the days, weeks and months after a concussion and why these neurological changes cause concussion symptoms including loss of consciousness, laps in memory, fatigue, anxiety, memory, food cravings and even catching a cold. Links mentioned: poweronpoweroff.com…
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[Part 1 of 2] Dr. Pastore and Lexie introduce concussions and traumatic brain injuries (TBI) - including what causes a concussion, the common symptoms, recovery time, and what to do to recover as quickly and efficiently as possible. Stay tuned for a more in-depth look at “The Neurochemistry of Concussions” next episode. Links mentioned: Light thera…
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Lexie and Dr. Pastore cover all things poop-related, including how food is turned into poop, what’s normal & what’s not. They discuss constipation, gas, diarrhoea, laxatives, fecal transplants and warning signs for when you should book an appointment with your doctor to discuss your digestive health.…
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Infertility may be the one and only symptom that a woman OR man has undiagnosed celiac disease - there may be no gastrointestinal distress or typical “digestion” symptoms you’d assume to be present.a Dr. Pastore discusses the most recent study around celiac disease research and then dives into the studies around infertility in celiacs, and how for …
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Celiac Disease: High Risk Groups, Related Disorders and Comorbidities
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Comorbidity is the presence of one or more additional medical conditions co-occurring with a primary condition. Dr. Pastore discusses the most common comorbidities (disorders and diseases) that are connected with celiac disease and the research that uncovers why this is the case. He also elaborates on the intestinal epithelial barrier, it’s importa…
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Dr. Pastore discusses the topic of obesity and the newest emerging studies showing it as one of the most common symptoms of undiagnosed celiac disease. He explains the misconception that undiagnosed celiac patients would appear underweight due to malnutrition; as well as what is physiologically happening in the gastrointestinal tract and throughout…
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Dr. Pastore and Lexie cover how certain variations of specific genes can affect your performance, your nutrition, your cravings and even how food tastes. In-depth topics include how genetics affect: High carbohydrate consumption and low HDL cholesterol levels How food tastes, and why some people can never get enough sugar How your risk for tendon/l…
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On Alzheimer’s Disease - a New Type of Diabetes
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Dr. Pastore and Lexie review diabetes, Alzheimer’s disease, why the emerging scientific evidence is showing that Alzheimer’s disease may be Type 3 diabetes, and what you can do NOW to decrease the likelihood of developing these diseases. Some important facts: Prolonged elevated glucose (blood sugar) levels damage blood vessels in the brain, disrupt…
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Dr. Pastore and Lexie discuss emerging foods in society today, including: -The artificial sweetener allulose, how it’s made and why you should be mindful of dosages -Plant-based “meats” such as the Impossible Burger & Beyond Meat, their protein quality and the downsides to how they are made & processed -An up & coming plant-based protein source hig…
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Dr. Pastore and Lexie discuss sunscreen, focusing on how the chemicals in the product designed to protect your skin against the sun’s harmful affects can be absorbed and negatively affect the inside of your body, and what you can do about it now. Dr. Pastore covers what SPF is and what the SPF number on your sunscreen bottle means; melanin, sunburn…
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We are all bicohemically unique, and much of that has to do with our genetic makeup. Dr. Pastore and Lexie discuss one of Dr. Pastore’s specialties as a practitioner - nutrigenomics; specifically functional nutrigenomics. Dr. Pastore covers what the research has shown and how he applies nutrigenomics with his patients to identify how their DNA sequ…
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Dr. Pastore and Lexie cover 5 popular supplements typically marketed for weight loss. Dr Pastore discusses CLA, apple cider vinegar, L-carnitine, green tea extract (EGCG) and skinny teas; what the actual research and studies have to shown, and how some of them, if taken daily, are actually doing much more harm than good.…
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Dr. Pastore and Lexie discuss some of the most common nutritional deficiencies in the standard North American diet. They look in depth at vitamin D, choline, magnesium, Omega 3 (EPA/DHA), zinc and iron and what these vitamins/minerals/nutrients do in the body, where we find them in food, how much we need daily and what blood tests Dr. Pastore recom…
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On Artificial Sweeteners & Sugar Alcohols
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In this episode, Lexie and Dr. Pastore discuss: • The types of naturally occurring sugar • Artificial sweeteners, how they are chemically processed and their negative health benefits, specifically the increasingly popular sweeteners aspartame and acesulfame potassium (ace-K) • Sugar alcohols and how they are processed • Plant-based & natural sweete…
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