Welcome to BIOTECH NATION !!! With understandable interviews requiring no background in science, BTN attracts a wide global audience. From everyday people looking for hope in treatments in development, to bioentrepreneurs interested in the experience of their fellow travelers, to venture capitalists looking for possibilities in cutting-edge breakthroughs, to scientists simply interested in the work of others, BioTech Nation is the voice of human endeavor, driving science to new realities for ...
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CRAFTED. is a show about great products and the people who make them. Incredible founders, makers, and innovators reveal how they build game-changing products and companies — and how you can, too. Honored twice by the Webby Awards as a top tech podcast. Discover the future of product development, technology, and AI on CRAFTED. Hosted by Dan Blumberg, an entrepreneur, product leader, and former public radio host. Each episode of CRAFTED. brings you closer to the founders, innovators, and tech ...
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Amadeus Capital Partners has been a trailblazer for three decades, investing in people who create transformational technologies and sustainable businesses. We’ve backed nearly 200 startups and scaleups across Europe and, more recently, in Latin America. In Amadeus and Friends, you’ll hear from some of the world’s greatest innovators in quantum computing, AI, biotech and more, sharing their commercial journeys, the highs and the lows, and how they’ve approached commercialisation with the supp ...
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Can the Mapping of Human Biology Lead to Better Drugs? Dr. Chris Gibson, Co-Founder & CEO Recursion Pharmaceuticals
21:42
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Dr. Chris Gibson, the co-founder and CEO of Recursion Pharmaceuticals in Salt Lake City. We talk about their efforts to map ALL of human biology, and how this mapping will lead to better drugs.By Moira Gunn
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The Integration Is the Innovation | Jeff Birkeland (SVP of Product at Included Health)
24:46
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Jeff Birkeland is the SVP of Product and Platform at Included Health, a company that aims to be the app on your phone that you first think of when you have a healthcare need. On this episode of CRAFTED., we explore why “the integration itself is the innovation.” Included Health has more than 2,000 employees across both technology and clinical care,…
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One Company, Two Different Drugs - It's All About Glucose - Too Much and Too Little! Nevan Charles Elam, Founder & CEO, Rezolute
18:52
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Glucose is essential for life. And the insulin we produce is designed to leave just the right of amount in our bodies for healthy functioning. Thus, when we underproduce insulin - or we overproduce it - the results can be devastating. Nevan Charles Elam, Founder and CEO of Rezolute, tells us about their work to treat the “diabetic eye condition”, D…
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Is It Cake or a Muffin? How to Position Your Product and Drive More Sales | April Dunford (bestselling author and advisor)
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April Dunford is an expert at product positioning. She’s advised hundreds of B2B companies on how they can make their products Obviously Awesome — that’s also the title of her bestselling book on positioning. On this episode of CRAFTED., April shares tips on how you can make your product standout and how you can drive more sales — that’s the focus …
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A Vaccine for Breast Cancer??? Dr. Amit Kumar, President & CEO, Anixa Biosciences
25:39
25:39
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This week on BioTech Nation, Dr. Amit Kumar, President and CEO of Anixa Biosciences, talks about their work on a breast cancer vaccine which targets a protein thought only to be expressed during breastfeeding. Building on research by the Cleveland Clinic, Dr. Kumar describes ongoing human clinical trials and their potential for women with BRCA muta…
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How Media Is Made Today: AI and a Modern CMS | Matt Monahan, President, Arc XP, The Washington Post
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Making media is hard. Distributing it to the right audience even more so. GenAI can help. Matt Monahan is the president of Arc XP at the Washington Post. On this episode, we're digging into the core technology of any media company: the content management system (CMS), why they’re so hard to build right and how new GenAI tools can reduce the toil re…
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Are Your Genes Failing You??? Dr. Noah Davidsohn, Co-Founder & CSO Rejuvenate Bio
16:50
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This week on Biotech Nation, Dr. Noah Davidsohn, Co-Founder and Chief Scientific Officer of Rejuvenate Bio. The discussion centers around the regulation of protein expression and its implications for aging and health. Dr. Davidsohn explains how aging disrupts the balance of protein production, leading to various diseases. Rejuvenate Bio's gene ther…
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My AI Teacher: Khan Academy and the Future of Education | Dr. Kristen Dicerbo (Chief Learning Officer)
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Dr. Kristen DiCerbo is Khan Academy’s Chief Learning Officer, where she sets the company's product, teaching, and learning strategy — with AI at the forefront. Khanmigo is amazing. It’s the GenAI-powered product from Khan Academy that helps students learn and teachers teach — and could revolutionize education. Khan Academy is used by 12 million stu…
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Living Longer??? Dr. Peter Diamandis, XPrize Founder and Author, "Longevity"
25:33
25:33
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This week of BioTech Nation, Dr. Peter Diamandis about his new book, "Longevity: Your Practical Playbook on Sleep, Diet, Exercise, Mindset, Medications, and Not Dying from Something Stupid". We explore his lifelong interest in extending human health span and discuss practical steps for a healthier, longer life, including sleep, diet, exercise, and …
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Great Software & Storytelling Is Emotional | Kelsey Hightower (Legendary Developer, Kubernetes Pioneer, Former Distinguished Engineer at Google)
51:28
51:28
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Kelsey Hightower is a legend. He regularly gives live software demos in front of tens of thousands of people, improvising them like it’s jazz. He’s a master storyteller and a master craftsman. He helped evangelize and establish Kubernetes and recently retired (at 42!) from Google where he was a distinguished engineer. Kelsey loves to level people u…
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Psychedelics... Prodrugs... What else? Dr. Sam Clark, CEO of Terran Biosciences
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This week on BioTech Nation, Dr. Sam Clark, CEO of Terran Biosciences, discusses prodrugs—modified drugs that improve absorption and efficacy. Also, Terran Biosciences is developing non-hallucinogenic psychedelics by blocking the serotonin 2A receptor and manufacturing psychedelics like LSD and psilocybin for research. Dr. Clark highlights Terran's…
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Driving Product-led Growth (PLG) With Customer.io Founder and CEO Colin Nederkroon
28:53
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Colin Nederkoorn is the founder and CEO of Customer.io, a top customer engagement platform that enables companies to send the right message to the right user at the right time on the right channel. The platform is used by Notion and lots of other top SaaS companies to personalize user onboarding and more. When Customer.io was founded in 2011, there…
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A Dual Approach to Combatting Hepatitis... Dr. Marianne De Backer, CEO at Vir Biotechnology
19:52
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This week on Biotech Nation, Dr. Marianne De Backer, CEO of Vir Biotechnology talks about their Phase 2 clinical trials targeting hepatitis B and D co-infections. Vir's approach uses two drugs: tobevibart (an antibody) and elebsiran (an siRNA). These drugs prevent the virus from entering liver cells and stop it from replicating. Preliminary results…
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Powering the World’s Hackathons | Brandon Kessler (Founder & CEO, DevPost)
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DevPost powers most of the world’s hackathons. And, according to founder and CEO Brandon Kessler, lately there is one overarching directive: “Executives from the top down are saying: `We need to do hackathons to uncover the value of ai.`” Nearly every one of the 1,200 hackathons DevPost powered last year was AI-centric. On this episode of CRAFTED.,…
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Solving Genetic Diseases??? Dr. Neil Kumar, Founder & CEO, BridgeBio Pharma
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This week on Biotech Nation, Dr. Neil Kumar, founder and CEO of BridgeBio Pharma. Dr. Kumar emphasizes that genetic diseases, particularly Mendelian diseases caused by single gene mutations, are solvable due to advancements in genetic measurement and understanding. He discusses BridgeBio Pharma's innovative corporate structure, which consists of mu…
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Solving Dinner & Building Wonder | Rich Przekop (VP, Product at Wonder)
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Wonder aims to be a “super app for mealtime”, with people turning to it for everything from delivery to groceries to meal kits and more... It’s a very ambitious food-tech startup founded by Marc Lore, the legendary founder who previously built, scaled, and sold Diapers.com and Jet.com (to Amazon and Walmart, respectively). Wonder is rapidly opening…
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The Next Ozempic or Wegovy... But Without the Injection??? Dr. Steffen-Sebastian Bolz, CSO, Aphaia Pharma
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What’s next after Ozempic and Wegovy and the like? How about a drug in development which releases all the relevant hormones, and not just GLP-1. And doesn’t require injecting. Dr. Steffen-Sebastian Bolz from Aphaia (ah-phi-ah) Pharma explains their approach, currently in Phase 2.By Moira Gunn
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FDA Approval! A New Model for BioPharma... Dr. Sam Blackman, Founder & Head of Research and Development, One Day Biopharmaceuticals
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This week on BioTech Nation, Dr. Sam Blackman, Founder and Head of Research and Development from Day One Biopharmaceuticals, shares the story behind the FDA approval of a groundbreaking drug for the most common childhood brain cancer. He talks about their innovative approach to starting a biopharma company and how it led to a newly FDA approved dru…
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Listen to Developers! | Justin Cormack (CTO, Docker)
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When Docker restructured, the company went back to its roots: super-serving developers. CTO Justin Cormack says that’s why the company is developer-obsessed, not customer-obsessed: “We really wanted to focus on the fact that it's the developer who loves Docker. It's the developer who is going to be using Docker every day…” Over the past decade, Doc…
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Everybody Has a Thyroid... What Could Go Wrong??? Dr. Mark Sumeray, CMO of Amolyt Pharma
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This week we have a best of rerun with Dr. Mark Sumeray from Amolyt Pharma. Dr. Sumeray talks about their innovative approach to treating hormonal conditions. We’ll talk about two – when your parathyroid has been injured or removed, often during thyroid surgery, and another – when the pituitary starts overproducing growth hormone.…
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New Frontiers of Health: AI, Psychedelics, the Gut-Brain Axis, and More! | Live from SXSW
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Software, hardware, and biotechnology are playing an increasingly transformative role in our mental health and wellness. On this episode of CRAFTED., recorded live on the “Next” stage at SXSW, we discuss what investors look for in these new companies and how they separate what’s real — and what’s near-term — from what’s hype. On stage with host Dan…
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Wearable Wonders! Dr. Daniel Kraft, Tech Nation Health Chief Correspondent
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13:38
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This week Dr. Daniel Kraft, Tech Nation Health Chief Correspondent, discusses advanced health tech. Dr. Kraft highlights his use of wearables like the Apple Watch, Oura ring, and non-invasive blood pressure monitors. He also introduces "otherables," which track health without being worn, using devices like cameras and modified WiFi. These technolog…
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How BetterUp Leverages AI + Human Coaches to Help People and Companies Flourish | Gabriella Rosen Kellerman (Chief Product and Innovation Officer)
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Dr. Gabriella Rosen Kellerman is the Chief Product and Innovation Officer at BetterUp, a multi-billion dollar startup that helps people and companies level up. Through a combination of human coaching and AI, BetterUp is able to offer the kind of executive coaching that used to be reserved for... executives. On this episode of CRAFTED. we dig into h…
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Making Music With AI – And Doing So Ethically | Diaa El All, Founder & CEO of Soundful
28:05
28:05
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28:05
Diaa El All is the founder and CEO of Soundful, which enables anyone to create brand new music in just a few seconds with AI. And on this episode of CRAFTED., we are literally making music. We’re also talking about the ethics of using AI to make music. Diaa has been very outspoken about what he sees as the misguided practices of other AI+music comp…
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Robo-Docs & VR Surgery??? Dr. Daniel Kraft, Tech Nation Health Chief Correspondent
13:56
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This week on BioTech Nation, Dr. Moira Gunn and Dr. Daniel Kraft discuss how robotics, AI, and virtual reality are transforming surgery. These technologies make procedures less invasive and improve training and outcomes worldwide. Future advancements may include tiny robots performing internal procedures. Security is crucial to prevent hacking of m…
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Asana’s Head of AI on the Profound Ways Work Is Changing | Paige Costello (Head of AI & Co-Head of Product Management at Asana)
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Paige Costello is the the head of AI and co-head of product at Asana and on this episode of CRAFTED. we're exploring what it means to ship products with AI, how AI will change the way work gets done, and how to organize your teams for success in this brave new world. We explore: How the future of work – and communicating about work – is changing Wh…
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No More Transfusions!!! Dr. John Scarlett, President and CEO of Geron Corporation
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Dr. John Scarlett, President and CEO of Geron Corporation talks about their drug Imetelstat for myelodysplastic syndrome (MDS). MDS patients often require frequent blood transfusions, impacting their quality of life. Imetelstat, a telomerase inhibitor, aims to reduce transfusion dependence by targeting cancer cells in the bone marrow. Phase three t…
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Closing the Innovation Gap!!! Dr. Daniel Kraft, Tech Nation Health Chief Correspondent
10:26
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Dr. Daniel Kraft, Tech Nation Health Chief Correspondent discusses the gap between medical innovation and its adoption into standard practice. He highlights that it typically takes 17 years for a medical discovery to become common practice, but big data and AI could accelerate this. He emphasizes the importance of sharing medical data and initiativ…
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The Virtual Cell??? Dr. Steve Quake, Head of Science at Chan Zuckerberg Initiative
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This week, Dr. Steve Quake from the Chan Zuckerberg Initiative about their goal to tackle all human diseases in the next century. We discuss CZI's innovative approach, including building Biohubs and funding collaborative research. Dr. Quake explains the importance of something called The Virtual Cell project, aiming to use AI to model every human c…
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How Can Sound Deliver Drugs??? Dr. Neal Kassell, Founder & Chair of Focused Ultrasound Foundation
16:48
16:48
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This week on Biotech Nation, I speak with Dr. Neal Kassell about focused ultrasound technology. We discuss its noninvasive approach, its diverse applications in treating various medical conditions, and its potential to revolutionize treatments for diseases like Alzheimer's, Parkinson's, and cancer. Dr. Kassell also shares insights into ongoing clin…
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70% of Breast Cancers and a Link to Prostate Cancer... Dr. Sean Bohen, President & CEO, Olema Oncology
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This week on BioTech Nation, we explore new efforts in treating cancer with Dr. Sean Bohen, President and CEO of Olema Oncology. We discuss progress in treating breast cancer, particularly ER+/HER2- breast cancer, which accounts for 70% of diagnoses this year. They examine the biology behind these cancers and how Olema's lead compound, palazestrant…
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Tiny RNAs, Big Cures!!! Dr. Sanjay Shukla, President and CEO, ATyr (ah-tire) Pharma
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This week - Dr. Sanjay Shukla, CEO of Atyr Pharma, discusses the revolutionary potential of mRNA technology in creating new medicines. They explore Atyr's pioneering approach to leveraging tRNA fragments for treating pulmonary sarcoidosis and other organ-specific conditions, aiming to improve patient outcomes while minimizing reliance on convention…
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How to Grow Your Startup. Featuring “Growth Levers and How to Find Them” Author and Startup Advisor Matt Lerner (Founder & CEO, SYSTM)
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“So if you take any great startup and look backwards, you'll see that 90 percent of their growth came from like 10 percent of the stuff that they tried. So how do you find that 10 percent as quickly as possible?” Matt Lerner has advised hundreds of startups on how to grow. Now, the CEO of SYSTM has written a book called Growth Levers and How to Fin…
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Visionary Women in VC – what the past tells us about the future!
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Amadeus Capital Partners CEO Anne Glover sits down with Catherine La Torre, Independent NED and former CEO of British Patient Capital, to delve into the dynamics of the UK venture capital industry. Catherine shares invaluable insights gleaned from her illustrious career journey, highlighting the remarkable achievements of British Patient Capital in…
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How Can a Treatment Become a Vaccine??? Dr. Peter DeMuth, Chief Scientific Officer at Elicio Therapeutics
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Dr. Peter DeMuth, Chief Scientific Officer of Elicio Therapeutics, discusses the revolutionary approach of detecting cancer at its earliest stages through circulating tumor DNA (ctDNA) tests. Highlighting their innovative treatment method, which aims to train the body's immune cells to recognize and destroy cancer cells, the episode explores the po…
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Cancer Vaccines??? Dr. Chris Pirie, Co-Founder & COO of HDT Bio
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In this week's episode, Dr. Moira Gunn interviews Dr. Chris Pirie from HDT Bio about their novel approach to cancer prevention through vaccines. They discuss leveraging mRNA technology to target specific tumor mutations and prime the immune system to recognize and eliminate cancer cells. Dr. Pirie highlights ongoing efforts to develop vaccines for …
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The April Fool’s Gag That Presaged the Future of Product Management | Janna Bastow (Founder & CEO of ProdPad & Founder, Mind The Product)
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On April 1st, 2013, ProdPad promised something revolutionary: “We now take your backlog of ideas, and with highly advanced big data crunching algorithm technology, automagically render a complete and accurate product roadmap. [...] The Auto-Roadmap Tool not only builds itself, but also covers for the hardest part of the Product Manager’s job: Getti…
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Live from SXSW! The Impromptu Rooftop Episode
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Enjoy this bonus, happy hour edition of CRAFTED., recorded live during SXSW. It’s a very unCRAFTED. CRAFTED. Featuring four innovators on a rooftop in Austin talking about what struck them at this year’s SXSW. Kick back and unwind with Christie Nicholson (Founder of the Studio for Communicating Complexity), Kwaku Aning (Director, Center for Innovat…
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Redefining Acute Myeloid Leukemia (AML) Treatment!!! Dr. Robert Ang, President & CEO of Vor Biopharma
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15:20
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This week I speak with Dr. Robert Ang from Vor Biopharma about their innovative approach to treating acute myeloid leukemia (AML). AML is a type of blood cancer that affects the bone marrow, leading to the overgrowth of cancerous cells. Dr. Ang explains that traditional treatments, such as chemotherapy and stem cell transplants, have limitations an…
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Fighting Inflammation, and Alzheimer's??? Dr. David Bearss, President & CEO Halia Therapeutics
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In this week's episode of BioTech Nation, Dr. David Bearss, President and CEO of Halia Therapeutics, discusses inflammation and its reduction over a lifetime and in response to various incidents. He unveils the inflammasome, a recently discovered protein complex critical in regulating inflammatory responses and its potential in treating chronic dis…
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Photonic’s Quantum Leap: an interview with Stef Simmons and Hermann Hauser
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Manjari Chandran-Ramesh, Partner on our Early Stage investing team embarks on an insightful journey into the cutting-edge realm of quantum computing with industry pioneers Professor Stephanie Simmons from Photonic Inc and Hermann Hauser, co-founder of Amadeus and Board Director of Photonic. The conversation delves into the challenges and opportunit…
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How to Navigate the Whitewater World of Work | Dr. Gabriella Rosen Kellerman (Chief Product & Innovation Officer at BetterUp and Author of Tomorrowmind)
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Career trajectories used to be like steamships: full steam ahead. And then they became more like sailboats: lots of tacking. But now… we’re swirling in whitewater. And, as the Chief Product and Innovation Officer at BetterUp, Dr. Gabriella Rosen Kellerman helps people build the skill they need to flourish: “When you're kayaking in the whitewater. I…
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Food as Medicine, A Personalized Prescription... Dr. Daniel Kraft, Tech Nation Health Chief Correspondent
10:21
10:21
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Tech Nation Health, Chief Correspondent Dr. Daniel Kraft discusses the concept of "food as medicine." Dr. Kraft emphasizes the evolving understanding of nutrition and its profound impact on health, advocating for a shift towards personalized nutrition using cutting-edge technologies. From continuous glucose monitors to AI-powered apps and sensor to…
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Repairing Minds, Naturally??? Mark Litton, President & CEO, Athira Pharma
22:38
22:38
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Alzheimer’s, Parkinson’s dementia, and other neurodegenerative diseases continue to be challenging, but now new science has led to a better understanding of the natural repair mechanisms in the brain. This, in turn, has generated new options for innovative treatments, and one such approach has entered late-stage human clinical trials. Dr. Mark Litt…
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“You Have to Invest Into Change.” Startup Lessons from Fintech OG and VC Daniel Kimerling, Founder of Deciens Capital and Standard Treasury
29:17
29:17
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“You have to invest into change. You cannot invest into stasis. Daniel Kimerling has a keen eye for the trends, technologies, and cultural shifts that are going to be big. A decade ago, he took an insight – that developers needed powerful tool so they could embed banking services into their apps – and launched Standard Treasury, the very first bank…
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Combatting Blood Clots!!! Dr. Daniel Bloomfield, Chief Medical Officer, Anthos Therapeutics
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This week, Dr. Daniel Bloomfield from Anthos Therapeutics discusses the prevalence and dangers of blood clots, particularly in patients with cancer. Dr. Bloomfield explains the difference between normal and abnormal blood clotting, the risks associated with blood clots in arteries and veins, and the challenges in balancing clot prevention with the …
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Heartburn, GERD, Cancer??? Dr. Lishan Aklog, CEO of Lucid Diagnostics
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Dr. Lishan Aklog from Lucid Diagnostics tells us about the path from GERD to, unfortunately, esophageal cancer, and about Lucid’s two-minute diagnostic test which can detect precancerous cells.By Moira Gunn
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Crafted Highlights from 2023 (Our New Trailer)
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A highlight reel that will will help you find great episodes in the Crafted show archive, featuring some of the incredible founders and product builders we featured in 2023. You'll hear voices belonging to the founders of Gusto, Lattice, Monte Carlo, Moov, Wevr, PS, as well as from senior leaders at AWS, Redesign Health, Betterment, Flatiron Health…
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From Tummy Tucks to Drug Trials??? Dr. Eric Merle, Chief Business Innovation Officer, GenoSkin
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Dr. Eric Merle from GenoSkin talks about how they are transforming drug discovery using discarded human skin from surgeries like tummy tucks, revolutionizing the process and accelerating drug development timelines.By Moira Gunn
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Innovating tomorrow: Deep tech insights from the Amadeus Early Stage team
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Discover the world of deep tech investing with the Amadeus Team in our latest podcast episode. In this episode, we introduce you to our Early Stage investing team and explore their diverse backgrounds and interests within the deep tech sector. The conversation investigates why deep tech stands out as an investment opportunity. From revolutionary ad…
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