Dr Matthew Panarella public
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Clinical Signs

Dr. Matthew Panarella

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This podcast is my take on topics in veterinary medicine relating primarily to dogs and cats. My mission is to educate and inform, for the general public, veterinarians and veterinary nurses. All are welcome. If you are interested in science, animals and veterinary medicine please give this podcast a try! Contact me with questions/comments at: askdrmatt@proton.me
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In this episode I discuss 4 topics: Muscle origin and insertion Strain vs. Sprain Water intoxication Pyometra I enjoy these potpourri episodes ideas arise from my own experiences and what I see in the news. Thankfully there are no links today. I am of the belief if you really are interested you will do your own research. When it comes to hardcore m…
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Canine parainfluenza virus (CPIV) as a sole disease agent is typically occurs as a mild, self limiting upper respiratory infection of dogs. Dogs are especially susceptible to CPIV in a crowded environment such as a kennel or animal shelter. CPIV is also one of the infectious agents that can be a component of Canine Infectious Tracheobronchitis (CIT…
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In this episode I discuss Infectious Canine hepatitis (ICH), a viral disease of dogs caused by Canine Adenovirus 1. ICH is one of the recommended core vaccines of dogs, per the AAHA guideline. This disease today would mostly effect young dogs, up to one year of age, especially the unvaccinated. The disease may cause many clinical signs such as mild…
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This episode covers canine distemper, caused by the canine distemper virus (CDV). CDV may have originated from the human measles virus over 1000 years ago in South America. CDV can be a devastating disease in dogs and other carnivores such as lions and other mammals such as sea lions. The virus is worldwide and can affect all dogs. There are many c…
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In this episode I discuss electrolytes (also called ions) such as sodium (Na) and potassium (K). These are elements from the periodic table that are essential for life. These electrolytes in an animals body exist in the blood, in the cell and between cells (called the interstitial space). The body maintains homeostasis through a variety of mechanis…
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In this episode, part 2 of corticosteroids, I review the side effects, precautions, drug interactions, testing recommendations and therapeutic uses. Also, I present my first 5 minute rant (5MR). I hope to occasionally give you a 5 minute or less rant on various topics, some veterinary some not. For those of you wanting to skip the rant, here are th…
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In this first of two episodes I discuss steroids, specifically corticosteroids. There are two types of corticosteroids, mineralocorticoids and glucocorticoids. Mineralocorticoids such as aldosterone primarily function to maintain the electrolyte balance in the body. One of the chief ways cells function is through the flow of electrolytes into and o…
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In this episode I review NSAIDS (nonsteroidal antiinflammatory drugs). NSAIDS are used to reduce fever (antipyretic), for pain relief (analgesia) and reduce swelling (antiinflammatory). For humans, there are numerous OTC (over the counter) NSAIDS available. There are also FDA approved veterinary NSAIDS as well as generic versions available for the …
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This episode discusses heart worm disease, caused by the internal parasite Dirofilaria immitis. The disease can affect all dogs, cats and ferrets. This is a vector born disease, transmitted by a mosquito bite. The heartworm life cycle is partially completed in the mosquito and finished in the animal that is bitten. Heartworms live in a symbiotic re…
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In this episode I discuss both thrombosis and embolisms. A thrombosis is a blood clot, an embolism can be a blood clot, but not always. Other types of emboli include fat and air. Clinical signs of a clotting issue may be in cats loss of use (paralysis) of the hind legs or tail. In dogs clinical signs may be dyspnea (bad breathing) where the animal …
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In this episode I follow up from episode 21 on the corn cob incident. Here I explain the possible ramifications from an animal swallowing a corn cob or other "foreign body". The damage caused by a foreign body can lead to various clinical signs such as vomiting, diarrhea, inappetance (not eating), to straining to defecate and anorexia. If not treat…
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In this episode I discuss my dogs misadventure with a piece of corn on the cob and how I remedied the situation. I only had access to over the counter 3% hydrogen peroxide, which I administered to my dog. This successfully caused her to regurgitate her dinner along with many chunks of chewed up corn cob. Thankfully there were no long term consequen…
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In this episode I discuss fleas, particularly the cat flea (Ctenocephalides felis), which is the most likely culprit in an infestation of both cats and dogs. The flea life cycle can be completed from egg to adult in as little as 3 weeks or as long as a year. The completion of the life cycle depends on 3 things, these are food, warmth and moisture. …
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In this episode I discuss fentanyl, a synthetic opioid used in veterinary medicine. There is an overdose epidemic in the USA concerning fentanyl and many media stories about this. Recently I came across a story about a person overdosing and possibly giving their dog fentanyl. Thankfully the dog survived. I have a link to this story and several othe…
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In this episode I discuss the book titled "How Doctors Think" by Jerome Groopman MD. I have found this book to be beneficial by helping me think more clearly, critically and to always perform a full physical exam on my patients. Although the book was written for physicians and their patients, I think it is just as valuable for veterinarians and our…
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In this episode I recount the recent history of an issue with my dog involving one of her toes. So far her outcome has been great. My dog's story segues in to a discussion about squamous cell carcinoma cancer in dogs and cats. Squamous cell carcinoma is cancer of the epithelial cells, which are found in the skin, the linings of the body and the hai…
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Welcome. This episode covers the pulse oximeter from how it functions, to what the readings mean and some troubleshooting tips. Without understanding ventilation, hypoxemia and hypoxia the data acquired by the pulse ox will not be useful to you. I recommend that you listen to episode 15 on this topic. In animals the pulse ox is typically placed on …
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In this episode I covered 2 miscellaneous topics, with the bulk of the podcast reserved for discussing ventilation, hypoxemia and hypoxia. This information provides the necessary understanding for the next episode which will cover the use of a pulse oximeter. Introduction 00:00-00:20 Pulmonary atelectasis, ramblings 00:20-04:19 Dog hair 04:20-05:21…
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In this the 14th episode, I discuss 3 topics. The first are the S1 and S2 heart sounds, S1 is the "lub" sound and the S2 is the "dup" sound. S1 sounds refer to the closing of the AV valves ( located between the atria and ventricle, these are the mitral valve on the left side and the tricuspid valve on the right) and the S2 refers to the closure of …
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Have you ever wondered why in a movie or TV show that a character holding a syringe will "flick" the syringe with a finger? Well, I have the answer. It is just being dramatic. In real life, a veterinarian/veterinary nurses will do this to remove air bubbles trapped in the syringe, although we do it as we draw the drug out of the vial. This step is …
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In episode 12 I have 3 topics of discussion. First is a deeper dive on my goals for the podcast, providing you with information. The second part of my goal is education. This is your responsibility to use the information I provide and put it to good use for the betterment of you, your pest and the world. My second topic concerns dog behavior and co…
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Episode 11 covers the rabies virus and it's effect on both animals and people. Rabies is a fatal, zoonotic disease of animals and humans. Most people are exposed by bats or cats, especially stray cats. Animals that are infected with the rabies virus will express bizzare behavioral signs, sometimes being aggressive and biting/attacking people and ot…
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In this, the tenth episode of the Clinical Signs podcast I cover the pro's and con's of gonadectomy on our dogs and cats. There are potential acute, short term consequences from the anesthesia and the surgical procedure itself. I am focused here on the long term benefits and consequences of removing the ovaries or testes. Long term benefits (The Go…
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Episode 9 is a grab bag of different topics. I start off discussing other podcasts that I enjoy, following up with more information about making a diagnosis, then I discuss symptomatic treatment, next is a discussion about population medicine vs. individual medicine, then I follow up with two research papers on feline parvo virus DNA recovered from…
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This episode dives in to Feline Parvo Virus (FPV). Known by other names such as feline distemper, feline plague and feline infectious enteritis, I prefer FPV. This is a serious contagious and infectious disease of cats primarily infecting kittens and unvaccinated or partially vaccinted cats. It is ubiquitous and worldwide. Cats are less likely to s…
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In this episode, I discuss the what the pulse is, how it originates, where to locate it , how to feel it and pulse quality. Of course taking an accurate pulse and feeling the difference in pulse quality is based on you practicing the technique. An easy way to do this is on yourself or if you have a cooperative dog or cat. I have also posted the ref…
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In this, the sixth episode I cover the sometimes devastating disease of dogs called Canine Parvo Virus (CPV). Also known as "parvo" this is a worldwide viral disease of young dogs. While there is no specific treatment, most dogs will recover from a parvo infection. There are vaccines available that all puppies should receive as a series from about …
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In this episode I give my opinion on a recent magazine article concerning the development of a pill to increase longevity in people and dogs. Apparently cats are too difficult to figure out how to accomplish this which translate in to it costs too much for the expected economic return. Welcome to the world of 2022, medical science fiction . As I co…
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In episode 4, I cover how a veterinarian goes about making a diagnosis. There are many formal steps to this process. The steps are: 1-the chief complaint (the problem or problems briefly summed up), 2-the history of the problem(s) and the animal, 3-a physical exam, 4-a list of possible diseases is generated, called differential diagnosises, 5-diagn…
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Hello and welcome back to the Clinical Signs Podcast. What does the term clinical signs mean? Is it the same as a symptom??? Clinical signs is term in veterinary medicine that is used to objectively describe what can be seen, felt, heard or smelled about an issue with an animal or pet. Some examples include the pet is lethargic or "lazy", vomiting …
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In this episode I discuss the tragedy of the mauling and death of two children in Tennessee by two dogs in their home. I review some available data from PubMed with links below regarding dog bites in the US and death by mauling from dogs in the US. Dog breed matters when discussing death caused by dogs. I discuss risk and some things to consider wh…
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Hello listeners! This is the introduction of my podcast 'Clinical Signs'. I am a veterinarian with over 30 year's experience and with this platform I hope to bridge the gap beteween veterinary medicine and the public. Also I will present medical and scientific topoics of interest to veterinarians and veterinary nurses, Finally, I will give my take …
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