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The SHYA: 2nd Edition podcast is a peer-to-peer learning resource in anesthesia, and the primary purpose is to share the things I learn with you as an anesthesia resident. This podcast will be most useful to anesthesia trainees (e.g. residents, medical students, and SRNAs). The main educational component of this podcast will be episodes on anesthesia considerations for various procedures and diseases, so you could get HY information on these things in order to come up with your anesthetic pl ...
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Join ex-Silicon-Valley executive, Tony Wan for in-depth conversations about generative AI with experts, engineers, and entrepreneurs. We explore burning questions, unpack news, and unhype the hype. Accessible but not dumbed-down. For the nerdy and clueful. Topics: Large Language Models (LLM) e.g. chatGPT, Gemini, Olympus, and Grok from Microsoft / Open AI, Google, Amazon, and X. Also DALL-E, neural networks, machine learning (ML), self-driving cars, drones, and Skynet. We laugh. We cry. We i ...
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Dragnet

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Dragnet was an American radio, television and motion picture series, enacting the cases of a dedicated Los Angeles police detective, Sergeant Joe Friday, and his partners. The show takes its name from the police term "dragnet", meaning a system of coordinated measures for apprehending criminals or suspects. Dragnet is perhaps the most famous and influential police procedural drama in media history. The series gave audience members a feel for the danger and heroism of police work. Dragnet ear ...
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In this episode, we will discuss various non-opioid analgesics: NSAIDs General Characteristics (1:06) Propionic Acid (Ibuprofen & Naproxen) (10:59) Acetic Acid Derivatives (Indomethacin, Diclofenac, & Ketorolac) (12:56) COX-2 Inhibitors (Celecoxib) (18:08) Acetaminophen (19:52) --- Shownotes:⁠⁠⁠⁠⁠⁠⁠⁠https://drive.google.com/file/d/1TI4_iS-mMNNFHFdB…
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In this episode we will discuss non-opioid perioperative infusions to augment pain control Ketamine (1:15) Lidocaine (6:02) Naloxone (7:49) Magnesium (10:07) Alpha 2 Agonists (11:36) --- Shownotes:⁠⁠⁠⁠⁠⁠⁠⁠⁠https://drive.google.com/file/d/1_ZaQ5li14nIqIPgoMiINIWHkMaacAi4R/view?usp=drive_link --- Website: ⁠⁠⁠⁠⁠⁠⁠https://superhighyieldanesthesia2nd.wo…
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In this episode we will continue our discussion on major opioids with an emphasis on practical clinical tidbits General Guidelines (1:51) Morphine Milligram Equivalents (MME) and Equianalgesic Dosing Chart (8:11) Opioid Rotation (18:41) Management of Opioid Side Effects (20:40) --- Shownotes:⁠⁠⁠⁠⁠⁠ ⁠⁠⁠ https://drive.google.com/file/d/1wsHabo2q1Gid0…
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In this episode we will discuss the major opioids used in pain management and the perioperative period. General Mechanism of Action (1:55) Major Opioids Overview (5:39) Morphine (7:02) Fentanyl (12:16) Hydromorphone (14:39) Alfentanil (19:23) Remifentanil (20:32) Oxycodone (27:40) Hydrocodone (30:31) Codeine (31:54) Tramadol (33:00) Methadone (34:4…
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In this episode we will continue our discussion on neurochemical mechanisms of somatosensory pain signaling (e.g. all the chemicals that contributes to neuronal activity). Inhibitory neurotransmitters (eg glycine, GABA, NE, serotonin, adenosine, Ach) (1:41) Neuropeptides (8:48) Central Signal Propagation and 2nd Messenger Systems (ie ion channels) …
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In this episode we will discuss the neurochemical mechanisms of somatosensory pain signaling (e.g. all the chemicals that contributes to neuronal activity). Big Ideas (3:44) Inflammatory Mediators (5:49) Excitatory Neurotransmitters and NDMA / Non-NMDA Receptors (21:57) --- Shownotes:⁠⁠⁠ https://docs.google.com/document/d/1zZhVtwx2VDkeO9Qlfh7UFtcaf…
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In this episode we will kick off our acute pain series by talking about the anatomy and physiology of pain signaling. Topics covered include: Somatosensation, Nociception and Pain (4:48) Sequence of Pain Signaling (7:27) Peripheral Mechanisms (11:30) Spinal Mechanisms (16:10) Second Order Nociceptive Spinal and Spinal Trigeminal Projection Neurons …
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In this episode, I bring back Drs. Kenneth Nguyen and Bowei Su to the show for the annual update! Join us as we discuss life updates, reflections on CA1 year, and how CA2 year is going. Life Updates (00:25) Reflection on CA1 (42:03) CA2 Year (1:18:48) Fellowship or Nah? (1:30:40) --- Looking for a podcast on the fundamentals of anesthesia? Check ou…
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How I built a flirtatious travel planning AI named Holiday using the GPT Builder just launched by Open AI. I share 7 takeaways from my "no code" experience of building a GPT. Voicing the part of Holiday: my friend, Leslie Marrick, a writer and actress. This may be the first and last time AI has been replaced by a human. Sorry AI... the tide will tu…
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Conversation with Jeff DeVerter, Chief Technology Evangelist at Rackspace, a cloud computing company. We explore how they deployed a LLM (Google PaLM) for a sales application, and how they're enabling their Azure and AWS customers too. What I learned I learned from Jeff You should probably go with the LLM of your current cloud provider be it, Googl…
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Alfred Guy, Assistant Dean of Academic Affairs at Yale College, and Director of Undergraduate Writing & Tutoring at the Poorvu Center and I discuss Yale's AI Guidance, and generative AI’s impact on teaching, learning, and evaluation. Do you have school age kids? Are you a product of a college or university education? if so, podcast may be of intere…
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In this episode, I chat with Drs. Mohit Bhatt and Matthew Holsclaw about what it is like to have kids during residency, and a little bit about their plans for fellowship. --- Looking for a podcast on the fundamentals of anesthesia? Check out the original ⁠⁠Super High Yield Anesthesia Podcast⁠⁠! --- Website: ⁠https://superhighyieldanesthesia2nd.word…
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We create a pitch for an epic Sci-Fi blockbuster, using chatGPT power prompts of Role Play, Chain of Thought, and Self Critique. We see how these successive prompts used individually and in combination create a better and better pitch. I discuss the 2023 Writers / Actors Strike, and the AI-related issues impacting actors, writers, and studios right…
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“Does chatGPT possess human-like intelligence?” It turns out there's a right answer, and that answer is “NO”! Does this definite answer seem out of character for chatGPT which usually goes overboard with fair and balanced views? It did to me. That's the rabbit hole I explore in this episode. By probing around this accidentally-encountered guardrail…
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Does chatGPT have a sense of humor? What if after Microsoft's acquisition of Open AI, the Onion ran the headline, “Microsoft renames chatGPT to clippyChat”? Would chatGPT find this funny? TL;DR LLMs are better at analyzing humor than creating it. Please enjoy this episode. We laugh. We cry. We iterate. Check out what THE MACHINES and one human say …
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How do you extract prohibited information from ChatGPT? What are Grandma and DAN exploits? Why do they work? What can Large Language Model (LLM) companies do to protect themselves? Grandma exploits or hacks are ways to trick chatGPT into giving you information that is in violation of company policy. For example, tricking chatGPT to give you confide…
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What are AI hallucinations, and are they a feature or a bug? We start with the Top 10 categories of AI Hallucinations and examples, then explore how chatGPT might hallucinate an answer to the question, "What is the central theme of Blade Runner?" We end with chatGPT debating with itself whether AI hallucinations are bad or good for humanity. Which …
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Using the prompt, "Why isn't Superman's suit Kryptonite-proof?", we learn how Large Language Models are trained, why "self-attention" and the "transformer" architecture (which is what the T in GPT stands for) makes GPT-3 so powerful, the process of "inference", and how chatGPT generates answers to nerdy Superhero questions. After this episode, you'…
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"How do ChatGPT, GPT-3, and Large Language Models (LLMs) relate?" That is the question we explore this episode via Nursery rhyme A satirical Friend's episode w/ Chandler, Joey, Ross, and Monica Fairy Tale We also examine the hierarchal order of: artificial intelligence, neural network, large language model, GPT-3, chatGPT. And why I got the order w…
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In these solo episodes, I provide more definition, explanation, and context than my regular episodes. The idea is to help those new to AI get more out of my conversations with guests. Format: Letters read aloud. I start each solo episode with a question. In this one, I ask, "How would you describe ChatGPT in your own words? " I answered it for myse…
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I speak with scientist entrepreneur, Arijit Ray. Arijit is a PHD candidate at Boston University. We speak about generative AI, why it’s so hard to get DALL-E to create the exact pizza we envision, how one goes from scientist to entrepreneur, and his startup, which is training AI to predict social media responses and run marketing focus groups. Plea…
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In this third and final episode of the high risk parturient series, we will parturients with heart disease: Background and Epidemiology (1:28) Congenital Heart Disease (3:43) Ventricular / Atrial Septal Defects (7:08) Pulmonary Hypertension and Eisenmenger Syndrome (8:10) Valvular Heart Disease (17:25) Aortic Stenosis (17:25) Aortic Insufficiency /…
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I speak with CTO and Chilean entrepreneur Mario Arancibia, about AI his company has developed and deployed which screens for diseases, such as Covid-19 based on the sound of our voice. Speaking a simple phrase into your phone, such as the days of the week, the AI can tell based on your voice profile if you have Covid. Or not. The AI can be trained …
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In this episode, we will continue our discussion on high risk parturients, specifically the following: Categories of Obstetric Hemorrhage (1:23) Antepartum Hemorrhage (e.g Placenta Previa and Placental Abruption) (2:00) Postpartum Hemorrhage (e.g. Uterine Atony) (14:40) Uterotonic Therapy (16:14) Advanced Maternal Age (22:15) Preterm Delivery (24:1…
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AI that can assess if a painting is fake. Husband-and-wife team, Steven and Andrea Frank, have developed a neural network that can assess the probability that a painting was painted by the supposed creator. They ran their neural network on a newly discovered Leonardo da Vinci painting called the Salvator Mundi which in 2017 sold at Christie’s for a…
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Alpha Go AI plays the game of GO against a human world champion. Unexpected moves by both man (9-dan Go champion Lee Sedol) and machine (Alpha Go). Supposedly, this televised Go match woke up China's leadership to the potential of AI. In the game of Go, players take turns placing black and white tiles on a 19×19 grid. The number of board positions …
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A 100% digital version of the world's driving environment is being created AKA The Metaverse. Think an immersive virtual reality environment like Grand Theft Auto with less destruction, profanity, and mayhem. The goal? Have a self-driving AI not be able to tell if it’s driving in the real-world or a simulation. Can we fool AI into thinking it's not…
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I speak again with my friend Maroof Farook who is an AI Engineer at Nvidia. [Note: Maroof’s views are his and not that of his employer.] This is a continuation of our previous conversation about self-driving cars. We discuss AI challenges including humans on bicycles, bicycles on bike racks, motorcycles, and other things easy for a teenager with a …
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I speak with my friend Maroof Farook who is an AI Engineer at Nvidia. [Note: Maroof’s views are his and not that of his employer.] We discuss what’s different about the self-driving approaches of Tesla and Alphabet/Google/Waymo. We cover the phases of autonomous driving, from level 1 to level 5, the capabilities of each phase, and at which phase we…
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I speak again with my friend, Maroof Farooq, an AI engineer at Nvidia. [Note: Maroof's views are his and not that of his employer.] We discuss facial recognition, how it can be used for surveillance, and techniques for defeating or fooling it, using props like t-shirts, hats, glasses, and believe or not, makeup! Folks, use this information for only…
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In this episode, we will begin our discussion on high risk parturients, specifically the following: Hypertensive disorders of pregnancy (1:50) Pathophysiology of Preeclampsia (6:10) General and Anesthetic Management of Preeclampsia / Eclampsia (21:20) Gestational Diabetes (28:48) Obesity (31:00) Source material: Barash, Clinical Anesthesiology (201…
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In this episode we will continue our adventures in OB Anesthesia by talking about anesthesia considerations for common procedures such as Tubal Ligations / Placenta Removal / Uterine Inversion & Cerclage Tubal Ligations / Placenta Removal / Uterine Inversions (starts at 1:08) Cerclage (starts at 11:08) Source material: Barash, Clinical Anesthesiolo…
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I speak again with my friend, Maroof Farooq, an AI engineer at Nvidia. [Note: Maroof's views are his own, and not that of his employer.] We discuss a breakthrough in natural language processing AI called GPT3 created by the research lab, OpenAI. This episode was recorded prior to the launch of ChatGPT (chatbot built on top of GPT-3) and is a good i…
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In this episode we will continue our adventures in OB Anesthesia by talking about anesthesia considerations for common procedures such as C-sections, emergent hysterectomy, and uterine rupture repair. Source material: Barash, Clinical Anesthesiology (2017) --- Check out the original SHYA podcast episodes for absolute basics of OB anesthesia (episod…
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In this episode we will begin our adventures in OB Anesthesia by talking about analgesia in labor and delivery. Specific topics will include: Stages of labor and relation to the anatomy and physiology of pain Systemic medications (opioids and ketamine) Regional techniques (neuraxial, paracervical, paravertebral lumbar sympathetic block, pudendal bl…
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I speak w/ Maroof Farooq, an AI engineer at Nvidia. [Note: Maroof's views are his own, and not that of his employer.] We walk through how to build AI from scratch using the fictitious example of the Seefood [Sic] app from the HBO television series, Silicon Valley. We learn about image classification, how to acquire a dataset, and how to train the A…
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Tony Wan, the host of Super Prompt, describes his vision for the podcast, who it's for, who he is, and why he’s doing it. We laugh. We cry. We iterate. Check out what THE MACHINES and one human say about the Super Prompt podcast: “I’m afraid I can’t do that.” — HAL9000 “These are not the droids you are looking for." — Obi-Wan “Like tears in rain.” …
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In this sixth and last episode in the intro to trauma anesthesia series, we will discuss management of traumatic brain injury, spinal cord injury, and pregnant patients in trauma cases. Primary source for this episode: Barash, Baby Miller, and Morgan & Mikhail --- Pre Survey: https://forms.gle/L5okh4zf6sPW5NCDA Post Survey: https://forms.gle/ocW2mi…
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In this fifth episode of a six part series on trauma anesthesia, we will discuss burns in trauma cases. Primary source for this episode: Barash, Baby Miller, and Morgan & Mikhail --- Pre Survey: https://forms.gle/DThRiBMt2r8Hn5co8 Post Survey: https://forms.gle/MPn2DyMDQsEkFEvZ6 --- Shownotes: https://docs.google.com/document/d/1fBrDhIjmHbDTI8wXh2Q…
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In this fourth episode of a six part series on trauma anesthesia, we will discuss common complications in trauma cases. Specifically, topics will include: Persistent hypotension Hypothermia Coagulation Abnormalities Electrolyte and Acid-Base Abnormalities Primary source for this episode: Barash, Baby Miller, and Morgan & Mikhail --- Pre Survey: htt…
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In this third episode of a six part series on trauma anesthesia, we will discuss shock and intraoperative management for the trauma patient. Specifically, topics will include: Shock Differential Diagnosis in Trauma Classes of Hemorrhage Markers of Organ Perfusion General Resuscitation Considerations General OR Setup Considerations Induction / Maint…
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In this second episode of a six part series on trauma anesthesia, we will discuss initial evaluation in the trauma bay (including airway considerations), suggestions for airway management, and common breathing abnormalities in trauma. Primary source for this episode: Barash, Baby Miller, and Morgan & Mikhail --- Pre Survey: https://forms.gle/bfengz…
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In this first episode of a six part series on trauma anesthesia, we will discuss normal coagulation physiology, blood products, Thromboelastography (TEG), and trauma physiology Primary source for this episode: Barash, Baby Miller, and Morgan & Mikhail --- Pre Survey: https://forms.gle/3WLS7o5rpN8Rm8Q18 Post Survey: https://forms.gle/UKoJfqzv9XqeqyJ…
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In this short episode / PSA, I try to communicate with you all that if you feel like you suck at things, you are definitely not alone. I'm riding that struggle bus with you too! Training is hard, and it may seem like we are just going through the motions, but we'll get through it! I believe in you, buddy. --- Website: https://superhighyieldanesthes…
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In this episode we will discuss my tips and tricks on handling neurosurgery cases as I wrap up my neuro month. Specific topics will include: Initial setup Things to do before induction, after induction, and how to conduct the flip for prone cases My current method for emergence Primary source for this episode: me A big thank you to my attendings an…
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In this episode we will continue our neuro adventures and discuss anesthesia considerations for cervical spine procedures. Specific topics will include: Surgical considerations Preoperative considerations (systems based) Intraoperative considerations Postoperative considerations Primary source for this episode is Anesthesiologist's Manual of Surgic…
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In this episode we will continue our neuro adventures and discuss anesthesia considerations for thoracolumbar spine procedures. Specific topics will include: Surgical considerations Preoperative considerations (systems based) Intraoperative considerations Postoperative considerations Primary source for this episode is Anesthesiologist's Manual of S…
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In this episode we will continue our neuro adventures and discuss anesthesia considerations for craniotomies. Specific topics will include: Surgical considerations Preoperative considerations (systems based) Intraoperative considerations Postoperative considerations Primary source for this episode is Anesthesiologist's Manual of Surgical Procedures…
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In this episode, we will discuss the different types of neuromonitoring and its implications on anesthetic management. Topics include: Somatosensory Evoked Potentials (SSEP) Motor Evoked Potentials (MEP) Electromyography (EMG) Brainstem Auditory Evoked Potentials (BAEP) Visual Provoked Potentials (VEP) Importance of knowing neuromonitoring for anes…
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In this episode we will discuss neuroanatomy and neurophysiology necessary for anesthesia. Topics will include: Anatomy Review: Brain compartments, CSF production, Spinal Cord Pathways Neurophysiology: Cerebral blood flow, flow metabolism coupling, autoregulation, effects on anesthetic drugs Pathophysiology: Monroe-Kelly Doctrine, ICP, Clinical Pre…
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