European Society of Intensive Medicine Talks
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EES EvalEdge, is the European Evaluation Society (EES) podcast series that provides insights into the implications of new and emerging technologies in evaluation and vice versa. The Podcast explores frontier technologies such as big data, machine learning, open data, geospatial analysis, blockchain and Internet of Things (IoTs). The purpose is to identify the role of evaluators and the field of evaluation in shaping how these technologies can be adapted in international development and in la ...
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The European Journal of Anaesthesiology publishes original work of high scientific quality, including laboratory work of clinical relevance. Subscribe today!
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The EJA Podcast collection…Q&A with Esther Pogatzki-Zahn and Dalia Aljohani, the first author of Experiences and perspectives of adults on using opioids for pain management in the postoperative period ...
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Listen to the Q&A between Esther Pogatzki-Zahn and Dalia Aljohani as they discuss the scoping review “Experiences and perspectives of adults on using opioids for pain management in the postoperative period”, found in the July 2024 issue of the EJA.By EJA
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ARDS Phenotyping: from disease understanding to future bedside perspectives
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To date, no specific pharmacotherapy has proven effective against acute respiratory distress syndrome ARDS. Results on the research domain have been ineffective in human trials, a gap attributed in part to clinical and biological heterogeneity in human ARDS. Therefore, a precision medicine approach is intended to address explicitly how such underly…
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EvalEdge ep. 8: A conversation with Burt Perrin on How to - and how not to - Evaluation Innovation
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How can evaluation support innovation in uncertain environments? In this episode, hosts Tom Ling and Mariana Branco discuss insights on evaluating innovation with expert Burt Perrin. Burt shares tips for evaluators on recognizing outliers, unintended effects, and adapting to change when innovation involves uncertainty. This episode also explore how…
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Mechanical circulatory support for cardiogenic shock: a network meta-analysis of randomized controlled trials and propensity score-matched studies
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Cardiogenic shock accounts for up to 5% of acute heart failure presentations and around 14–16% of patients reported in cardiac intensive care datasets. It complicates up to 15% of all myocardial infarctions and is the leading cause of death post-infarction. Using pharmacological agents alone may increase left ventricular afterload and myocardial ox…
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The communication between families of critically ill patients who manifest prolonged disturbances in the consciousness such as patients under sedation, in a coma, or delirium, and the caregivers became very difficult during the stay of the patient in the ICU. On the other side, the memories of the patients are distressing and confusing and make the…
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The EJA Podcast collection…Q&A with Jean-Michel Constantin and Marcus Schultz, an author of Effects of closed loop ventilation on ventilator settings, patient outcomes and ICU staff workloads – a systematic ...
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Listen to the Q&A between Jean-Michel Constantin and Marcus Schultz as they discuss the systematic review “Effects of closed loop ventilation on ventilator settings, patient outcomes and ICU staff workloads – a systematic review”, found in the June 2024 issue of the EJA.By EJA
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Professional burnout has been described by WHO as a syndrome conceptualised as resulting from chronic workplace stress that has not been successfully managed. Intensive care unit (ICU) professionals are at high risk of experiencing burnout due to the presence of patients with life-threatening illnesses, the observed discrepancies in job demands, re…
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Inflammatory subphenotypes in patients at risk of ARDS: evidence from the LIPS-A trial
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Acute respiratory distress syndrome (ARDS) remains a life-threatening syndrome, resulting in high morbidity and mortality. In ARDS patients and mechanically ventilated critically ill patients, two distinct subphenotypes, presenting hyper- and non-hyperinflammatory characteristics, have been identified. Studies show that early identification of the …
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The EJA Podcast collection…Q&A with Marc Samama and Oliver Grottke, the first author of Clinical guideline on reversal of direct oral anticoagulants in patients with life threatening bleeding
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Listen to the Q&A between Marc Samama and Oliver Grottke as they discuss the guideline “Clinical guideline on reversal of direct oral anticoagulants in patients with life threatening bleeding”, found in the May 2024 issue of the EJA.By EJA
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Brain ultrasound for the general intensivist
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Cerebral ultrasound is a developing point-of-care tool for intensivists and emergency physicians, with an important role in diagnosing acute intracranial pathology. The use of transcranial Doppler has expanded over the last years, opening a new window to the assessment of cerebral anatomy not only in neurocritical patients but also in general ICU a…
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EvalEdge ep21: AI, Monitoring & Evaluation in Challenging Environments
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How can artificial intelligence enhance monitoring and evaluation work in challenging environments? In this episode, hosts Valentine Gandhi and Alena Lappo discuss the opportunities and ethical considerations of using AI tools like ChatGPT for qualitative data analysis with their guest Dr. Carolyn Fonseca. Dr. Fonseca shares her experiences pilotin…
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Phenotyping and endotyping patients to optimally set nutrition targets
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Nutrition plays a vital role in the management of critically ill patients, and a tailored approach based on patient assessment, nutritional requirements, and clinical status is essential for optimising outcomes and promoting recovery. The concept of patient phenotyping and endotyping will help clinicians to better target nutrition interventions for…
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Uncovering heterogeneity in sepsis: a comparative analysis of subphenotypes
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Sepsis is a life-threatening organ dysfunction caused by a dysregulated host response to an infection. Despite progress in the understanding of sepsis pathophysiology, no specific treatment has proven successful. The precision therapy, a greater understanding of the heterogeneity of sepsis is needed. Recent approaches to measuring sepsis heterogene…
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ECMO PAL: using deep neural networks for survival prediction in venoarterial extracorporeal membrane oxygenation
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VA-ECMO outcome scores have been previously developed and used extensively for risk adjustment, patient prognostication, and quality control across time and centres. The limitation of such scores is the derivation by using traditional statistical methods which are not capable of covering the complexity of ECMO outcomes. The Extracorporeal Life Supp…
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The EJA Podcast collection…Q&A with Patrice Forget and Esther Pogatzki-Zahn, the last author of Perioperative pain management models in four European countries: A narrative review of differences, similarities ...
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Listen to the Q&A between Patrice Forget and Esther Pogatzki-Zahn as they discuss the article “Perioperative pain management models in four European countries: A narrative review of differences, similarities and future directions”, found in the March 2024 issue of the EJA.By EJA
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The EJA Podcast collection…Q&A with Claudia Spies and Finn Radtke, authors of Update of the European Society of Anaesthesiology and Intensive Care Medicine evidence-based and consensus-based guideline ...
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Listen to the Q&A with Claudia Spies and Finn Radtke as they discuss the guideline, “Update of the European Society of Anaesthesiology and Intensive Care Medicine evidence-based and consensus-based guideline on postoperative delirium in adult patients”, found in the February 2024 issue of the EJA.By EJA
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The EJA Podcast collection…Q&A with Mariachiara Ippolito and Andrea Cortegiani, authors of Peri-operative night-time work of anaesthesiologists: A qualitative study of critical issues and proposals
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Listen to the Q&A with Mariachiara Ippolito and Andrea Cortegiani as they discuss the qualitative study, “Peri-operative night-time work of anaesthesiologists: A qualitative study of critical issues and proposals”, found in the January 2024 issue of the EJA.By EJA
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The EJA Podcast collection…Q&A with Bernard Walder, Giovanna Lurati Buse and Michelle Chew, author of the ESAIC focused guideline for the use of cardiac biomarkers in perioperative risk evaluation
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Listen to the Q&A between Bernard Walder, Giovanna Lurati Buse and Michelle Chew as they discuss the guideline “ESAIC focused guideline for the use of cardiac biomarkers in perioperative risk evaluation”, found in the December 2023 issue of the EJA.By EJA
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Towards model-informed precision dosing of piperacillin: multicenter systematic external evaluation of pharmacokinetic models in critically ill adults with a focus on Bayesian forecasting
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Numerous Population Pharmacokinetic (PopPK) models have been developed for Piperacillin (PIP), most of which are based on small monocentric studies and may not be generalizable to other populations. A recent evaluation of six PIP models in 30 ICU patients receiving CI demonstrated large inter-model variability regarding predictability. The transfer…
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Green ICU - Environmental Sustainability in intensive care
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The concept of a "green ICU" is increasingly important in today's world, as sustainability and environmental considerations become integral to healthcare practices. Hospitals, including ICUs, can have a substantial environmental footprint due to energy consumption, waste generation, and resource use. Implementing green practices reduces this impact…
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EvalEdge ep20 - Digitalising for Impact: Lessons from Naples' Archeology Museum
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How to evaluate the social impact of a digitization policy of a Museum? In this EvalEdge episode, hosts Marco Lorenzoni and Alena Lappo interview Dr. Erica Melloni and Dr. Ludovico Solima about their evaluation of this aspect of Naples' National Archaeology Museum, conducted in 2020. Faced with challenges defining wellbeing and limitations from COV…
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Diving into ARDS with Prof. Gattinoni. From the new guidelines to bedside applied physiology.
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Acute respiratory distress syndrome (ARDS) is the term applied to a spectrum of conditions with different etiologies that share common clinical-pathological characteristics including: increased permeability of the alveolo-capillary membrane, resulting in inflammatory edema; increased non-aerated lung tissue resulting in higher lung elastance (lower…
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The EJA Podcast collection…Q&A with Sander Kempenaers, author of Remimazolam and serious adverse events: A scoping review
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Listen to the Q&A with Sander Kempenaers as they discuss the guideline “Remimazolam and serious adverse events: A scoping review”, found in the November 2023 issue of the EJA.By EJA
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The EJA Podcast collection…Q&A with Jochen Hinkelbein, Cardiac arrest in the perioperative period: a consensus guideline for identification, treatment, and prevention...
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Listen to the Q&A with Jochen Hinkelbein as they discuss the guideline “Cardiac arrest in the perioperative period: a consensus guideline for identification, treatment, and prevention from the European Society of Anaesthesiology and Intensive Care and the European Society for Trauma and Emergency Surgery”, found in the October 2023 issue of the EJA…
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The EJA Podcast collection…Q&A with Esther Pogatzki-Zahn and Eric Albrecht, author of The postoperative analgesic efficacy of liposomal bupivacaine versus long-acting local anaesthetics for peripheral ...
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Listen to the Q&A between Esther Pogatzki-Zahn and Eric Albrecht as they discuss the article “The postoperative analgesic efficacy of liposomal bupivacaine versus long-acting local anaesthetics for peripheral nerve and field blocks: A systematic review and meta-analysis, with trial sequential analysis”, found in the September 2023 issue of the EJA.…
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The EJA Podcast collection…Q&A with Patricia Lavand'homme and Patrice Forget, author of Opioid-free anaesthesia: should we all adopt it? An overview of current evidence
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Listen to the Q&A between Patricia Lavand'homme and Patrice Forget as they discuss the article “Opioid-free anaesthesia: should we all adopt it? An overview of current evidence”, found in the August 2023 issue of the EJA.By EJA
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The EJA Podcast collection…Q&A with Tino Münster and Marcelo Gama de Abreu, author of Variable ventilation versus stepwise lung recruitment manoeuvres for lung recruitment: A comparative study in an experimental ...
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Listen to the Q&A between Tino Münster and Marcelo Gama de Abreu as they discuss the article “Variable ventilation versus stepwise lung recruitment manoeuvres for lung recruitment: A comparative study in an experimental model of atelectasis”, found in the July 2023 issue of the EJA.By EJA
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Sepsis-associated acute kidney injury in the intensive care unit. A multicenter observational study
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Sepsis‐associated acute kidney injury (SA‐AKI) is a common, increasingly prevalent problem in the intensive care unit (ICU). The association between sepsis and AKI has been studied previously. However, the lack of a reproducible and standardized consensus definition has limited the interpretability of available knowledge. In order to assess SA-AKI …
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Patient Transportation in Critical Care: introduction to our ACE course
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Transportation of critically ill patients is inevitable in most health systems. Prehospital transportation (PHT) may be necessary after a major injury or as a result of a life-threatening illness – for example, myocardial infarction, intracranial haemorrhage, or metabolic coma. On our ESICM Academy, we offer a course series on Patient Transportatio…
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Intensive care units (ICU) are the most peculiar units in hospitals where the quality and safety of health care delivery should be at the highest level. The most critical patients are treated in this unit, posing all healthcare professionals working there with continuous physical and emotional challenges. ICU teams are composed of different profile…
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Artesunate treatment in severely injured patients with traumatic haemorrhage
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Multiple organ dysfunction syndrome (MODS) is common after major trauma, affecting up to two-thirds of patients with critical injuries. Post-trauma MODS is associated with a mortality of over 20% and poor long-term outcomes in those who survive. Current management is supportive, and there are no specific pharmacological agents that prevent organ dy…
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Life after sepsis in adult and paediatric patients
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Sepsis is a life-threatening acute organ dysfunction secondary to infection and affects more than 19 million people annually. In 2017, it was estimated that almost 49 million people were infected by sepsis, and half of those cases occurred in children under 5. In-hospital mortality has declined over the years, resulting in a large number of sepsis …
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Severe meningoencephalitis in the ICU: results from the EURECA study
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Central nervous system (CNS) infections significantly burden ICU physicians' daily clinical work. Diagnosis can be challenging, and timely management is of the utmost importance. Meningoencephalitis is one of the CNS infections for which the epidemiological studies conducted in adult patients suggest that approximately one in two will require care …
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