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Notable Nobels is a podcast about the Nobel Prize in Physiology or Medicine. The Nobel Prize in Physiology or Medicine is awarded to scientists who have made notable discoveries in the fields of Life Science and Medicine, and these discoveries have a history of profoundly influencing society and civilization. Each episode covers the prize awarded for a particular year, and with over 100 years of prizes, there’s a lot to talk about!
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Episode 23: Pharmacognosy - Drugs from Natural Sources 2015a
27:38
27:38
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This episode covers one half of the 2015 Nobel Prize in Physiology or Medicine, which was awarded to Tu Youyou. The Nobel Assembly at the Karolinska Institute chose to give Tu the award “for her discoveries concerning a novel therapy against malaria”. Topics include Tu’s discovery of the anti-malarial drug artemisinin from an ancient Chinese text, …
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This episode covers the 2023 Nobel Prize in Physiology or Medicine, which was awarded to Katalin Karikó and Drew Weissman. The Nobel Assembly at the Karolinska Institute chose to give Karikó and Weissman the award “for their discoveries concerning nucleoside base modifications that enabled the development of effective mRNA vaccines against COVID-19…
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This episode covers the 2020 Nobel Prize in Physiology or Medicine, which was awarded to Harvey J. Alter, Michael Houghton, and Charles M. Rice. The Nobel Assembly at the Karolinska Institute chose to give Alter, Houghton, and Rice the award “for the discovery of Hepatitis C virus”. Topics include the recognition that another hepatitis virus existe…
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This episode covers one half of the 1976 Nobel Prize in Physiology or Medicine, which was awarded to Baruch S. Blumberg. The Nobel Assembly at the Karolinska Institute chose to give Blumberg the award “for [his] discoveries concerning new mechanisms for the origin and dissemination of infectious diseases”. Topics include the unusual research route …
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Episode 19: Cervical Cancer and HPV 2008b
27:26
27:26
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This episode covers one half of the 2008 Nobel Prize in Physiology or Medicine, which was awarded to Harald zur Hausen. The Nobel Assembly at the Karolinska Institute chose to give zur Hausen the award “for his discovery of human papilloma viruses causing cervical cancer”. Topics include the use of Pap smears to screen for cervical cancer, zur Haus…
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This episode covers one half of the 2008 Nobel Prize in Physiology or Medicine, which was awarded to Luc Montagnier and Françoise Barré-Sinoussi. The Nobel Assembly at the Karolinska Institute chose to give Montagnier and Barré-Sinoussi the award “for their discovery of human immunodeficiency virus”. Topics include how the AIDS pandemic unfolded at…
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Episode 17: Retroviruses and Reverse Transcriptase 1975
25:53
25:53
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This episode covers the 1975 Nobel Prize in Physiology or Medicine, which was awarded to David Baltimore, Renato Dulbecco, and Howard Temin. The Nobel Assembly at the Karolinska Institute chose to give Baltimore, Dulbecco, and Temin the award “for their discoveries concerning the interaction between tumor viruses and the genetic material of the cel…
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Episode 16: Src and the Essence of Cancer 1989
28:49
28:49
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This episode covers the 1989 Nobel Prize in Physiology or Medicine, which was awarded to J. Michael Bishop and Harold Varmus. The Nobel Assembly at the Karolinska Institute chose to give Bishop and Varmus the award “for their discovery of the cellular origin of retroviral oncogenes”. Topics include Bishop and Varmus’ discovery of the first cellular…
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This episode covers one half of the 1966 Nobel Prize in Physiology or Medicine, which was awarded to Peyton Rous. The Nobel Assembly at the Karolinska Institute chose to give Rous the award “for his discovery of tumor-inducing viruses”. Topics include Rous’ discovery of a virus that caused cancer in chickens, how that sparked a search for cancer-ca…
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This episode covers the 1954 Nobel Prize in Physiology or Medicine, which was awarded to John Enders, Thomas Weller, and Frederick Robbins. The Nobel Assembly at the Karolinska Institute chose to give Enders, Weller, and Robbins the award “for their discovery of the ability of poliomyelitis viruses to grow in cultures of various types of tissue”. T…
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This episode covers the 1951 Nobel Prize in Physiology or Medicine, which was awarded to Max Theiler. The Nobel Assembly at the Karolinska Institute chose to give Theiler the award “for his discoveries concerning yellow fever and how to combat it”. Topics include the discovery that yellow fever is spread by mosquitos, the discovery that yellow feve…
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Episode 12: DDT - A Double Edged Sword 1948
23:14
23:14
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This episode covers the 1948 Nobel Prize in Physiology or Medicine, which was awarded to Paul Hermann Müller. The Nobel Assembly at the Karolinska Institute chose to give Müller the award “for his discovery of the high efficiency of DDT as a contact poison against several arthropods”. Topics include the use of DDT to control the spread of insect-bo…
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Episode 11: Antibiotics Part III - Streptomycin 1952
26:36
26:36
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This episode covers the 1952 Nobel Prize in Physiology or Medicine, which was awarded to Selman Waksman. The Nobel Assembly at the Karolinska Institute chose to give Waksman the award “for his discovery of streptomycin, the first antibiotic effective against tuberculosis”. Topics include the isolation of streptomycin, how antibiotics work molecular…
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Episode 10: Antibiotics Part II – Penicillin 1945
23:16
23:16
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This episode covers the 1945 Nobel Prize in Physiology or Medicine, which was awarded to Alexander Fleming, Ernst Chain, and Howard Florey. The Nobel Assembly at the Karolinska Institute chose to give Fleming, Chain, and Florey the award “for the discovery of penicillin and its curative effect in various infectious diseases”. Topics include Fleming…
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Episode 9: Antibiotics Part I – Sulfa Drugs 1939
26:43
26:43
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This episode covers the 1939 Nobel Prize in Physiology or Medicine, which was awarded to Gerhard Domagk. The Nobel Assembly at the Karolinska Institute chose to give Domagk the award “for the discovery of the antibacterial effects of prontosil.” Topics include the process Domagk used to discover prontosil, the fashion industry’s largest dye company…
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This episode covers the 1903 Nobel Prize in Physiology or Medicine, which was awarded to Niels Ryberg Finsen. The Nobel Assembly at the Karolinska Institute chose to give Finsen the award “in recognition of his contribution to the treatment of diseases, especially lupus vulgaris, with concentrated light radiation, whereby he has opened a new avenue…
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This episode covers the 1928 Nobel Prize in Physiology or Medicine, which was awarded to Charles Jules Henri Nicolle. The Nobel Assembly at the Karolinska Institute chose to give Nicolle the award “for his work on typhus”. Topics include some history of typhus epidemics, the work Nicolle did to show lice transmit typhus, and the unusual biology of …
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This episode covers the 1926 Nobel Prize in Physiology or Medicine, which was awarded to Johannes Fibiger. The Nobel Assembly at the Karolinska Institute chose to give Fibiger the award “for his discovery of the Spiroptera carcinoma”. This Nobel Prize has been called one of the biggest blunders made by the Karolinska Institute. Topics include Fibig…
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This episode covers the 2005 Nobel Prize in Physiology or Medicine, which was awarded to Barry J. Marshall and J. Robin Warren. The Nobel Assembly at the Karolinska Institute chose to give Marshall and Warren the prize “for their discovery of the bacterium Helicobacter pylori and its role in gastritis and peptic ulcer disease”. Topics include the s…
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This episode covers the 1905 Nobel Prize in Physiology or Medicine, which was awarded to Robert Koch. The Nobel Assembly chose to give Koch the award “for his investigations and discoveries in relation to tuberculosis”. Koch's key contribution was the development of a set of criteria for experimentally proving that a particular microorganism causes…
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This episode covers the 1907 Nobel Prize in Physiology or Medicine, which was awarded to Charles Louis Alphonse Laveran. The Nobel Assembly chose to give Laveran the award “in recognition of his work on the role played by protozoa in causing diseases". The protozoa that Laveran is most known for is the malaria parasite. Topics include Laveran’s ide…
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This episode covers the second Nobel Prize in Physiology or Medicine, which was awarded to Sir Ronald Ross in 1902. The Nobel Assembly chose to give Ross the award “for his work on malaria, by which he has shown how it enters the organism and thereby has laid the foundation for successful research on this disease and methods of combating it.” Topic…
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Welcome! This first episode covers the very first Nobel Prize in Physiology or Medicine, which was awarded to Emil von Behring in 1901. The Nobel Assembly chose to give Behring the first award "for his work on serum therapy, especially its application against diphtheria”. Topics include how Behring used serum therapy to treat diphtheria, how serum …
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