Dr Elina Berglund is the CEO/Co-founder of Natural Cycles, which she has grown to 2M users. When every other app seemed to be free — she made a brave decision: She charged her users a monthly fee. And it worked... 0:57 - The Birth of Natural Cycles2:57 - The Decision to Charge from the Start3:47 - Building Trust Through Pricing4:23 - From Personal …

Konstantin started Kaia Health after paying $50,000 to cure his back pain at an elite pain rehab centre. It worked. But it seemed stupid. Why did this need to cost $50,000? Kaia Health has since raised $125M and helped 625,000 users. 0:00 The 90 second story 1:22 How did he grow 20% every week? 2:15 Market timing is everything 7:43 We never put pre…

Jon Ronson is one of the most interesting people alive today — period.He’s the author of the Men Who Stare at Goats, So You’ve Been Publicly Shamed and The Psychopath Test — which spent 10 weeks on the New York Times bestseller list.His two Ted talks have been watched 20 million times, his books have been brought to life by George Clooney on the bi…

Max Parmentier is the CEO of Birdie, a Series B AgeTech startup who have raised $52M from the likes of Sofina, Omers Ventures and Index Ventures — and captured 10% of the UK market whilst currently scaling into Europe. 0:00 Intro 2:37 Shopify vs Amazon model in AgeTech 7:26 Product pivots: D2C never wins 11:56 Predictive AI AgeTech 13:58 I pitch an…

Tom Wicher is CEO of DrDoctor — who have served over 20M patients and just raised £10M in their recent Series A round. But he spent the first 7 years bootstrapping, and diverged from his colleagues: Opting for the slow and steady gentle disruption path. Why? 0:00 Gentle disruption beats move fast and break things 3:36 Picking a problem in healthcar…

Drug discovery is becoming more expensive and producing less results than ever before (Eroom's Law)—why?One of the ballooning costs are clinical trials. Pharma/biotech often outsource their trials to CROs (contract research organisations).But many CROs are incentivised to make trials as bloated and inefficient as possible. That means more money and…

Rewind.ai just raised their Series A at a valuation of $350M. Investors include Andreesen Horowitz, Reddit’s Alexis Ohanian and OpenAI’s Sam Altman.Rewind sits on your computer and phone, and watches everything you do. Then you can ask it questions like: What was that really great Mediterranean recipe I looked at last month? Or I’ve got a call with…

People are wearing Apple Watches to their wedding days. Has this whole 'quantified self' movement gone bananas? Is any of this data actually useful?I spoke to Maitham Dib about this. He's building Vital (YC21); a startup which makes all wearable/lab data available to other startups/companies.0:00 Wearable data is mostly useless3:22 The case for wea…

Dr Jared Dashevsky writes Healthcare Huddle (acquired by Workweek). He's scaled to over 30,000 subscribers. And it was pretty simple. Here are 12 frameworks that work for healthcare content creation (and mistakes to avoid). 0:00 Intro 1:14 Consistency is king; systematise it 7:40 McKinsey reverse pyramid principle for writing 9:10 You need to have …

Despite $billions of investment into the sector — there are still no AI discovered drugs on the market. Why?Recursion Pharmaceuticals (NASDAQ: RXRX) is one of the hottest AI drug discovery companies on the market. Especially after NVIDIA's $50M investment into them.Dr Imran Haque (SVP of AI and Digital Sciences) explains why AI drug discovery is so…

0:00 NVIDIA's $50M investment into Recursion Pharmaceuticals2:28 NVIDIA is becoming a seed investor3:45 Bull case for Recursion Pharmaceuticals9:20 Recursion's two big acquisitions13:05 How are Recursion going to make money?14:15 Recursion is overhyped19:45 Recursion is unprofitable22:21 Kim Kardashian's full body MRI scan 26:03 Longevity doctor's …

Ever waited months for a scan? Scan.com is making getting a scan as easy as booking an Uber. Behind the scenes of the disruptor changing medical imaging forever.0:00 Race to the bottom?1:34 AirBnB 11 star framework9:57 Scan.com looks really easy to build — what's hard about it?12:19 Lessons from working at Deliveroo15:14 How do you make a lot of mo…

0:00 David Sinclair's controversial claim 1:39 Bull v bear case6:23 David Sinclair's history of exaggerating and profiteering8:34 Adam Neuman's involvement11:40 Raising from unsophisticated investors16:30 Why aren't big pharma interested in longevity?22:45 Cynics are right, optimists get rich25:26 Will a longevity drug be the most valuable therapeu…

0:00 Why not let the builders build? Move fast and break things? 1:56 Why don't you ban people from googling their symptoms? 3:28 Is a disclaimer enough? 5:27 Why are LLMs difficult to regulate? 10:13 Move fast and kill patients — principal agent problem 12:23 People aren't idiots (they are) 14:20 Dr ChatGPT will never work 17:35 Spotting bubbles i…

Daniel Ek (Spotify Founder) has raised $65M for his new longevity startup: Neko Health.0:00 What is Neko Health2:18 They're doing nothing new5:33 The bull case; why it's going to be huge7:47 How are they possibly going to make money!?18:30 Why aren't they doing full body MRI?20:26 The bear case; why this will fail25:13 Smells a bit hypey29:15 The r…

0:00 Leaked secret Apple health report 5:06 What Apple are up to in healthcare 9:21 Decentralised clinical trials 11:35 Apple healthcare leaked documents controversy 15:38 Apple is going to become a health insurer 23:07 Imran's advice to Tim Cook 26:11 Being a healthcare provider is unprofitable 28:12 Apple will make a longevity/subscription health…

Huma is about to reach a 1 billion dollar valuation, and is thriving while other digital health companies are dying. But what’s their secret sauce? Dan Vahdat is the Johns Hopkins dropout — who meticulously studied the successful business practices of big pharma, and using these, has created the 'soonicorn' digital health company that’s about to ta…

0:00 Intro1:04 The genius business model of GetHarley5:26 How important is marketing? 50% of revenue14:57 Why aren't they doing cooler more innovative stuff?22:38 What verticals would we expand GetHarley's biz model to24:37 Vitamin vs painkiller27:49 Why have investors put so much money into GetHarley?31:00 Feedback and outroLinks mentionedGetHarle…

0:00 Intro 0:20 DEA comes after DTC health startups 3:18 How DTC health startups hacked customer retention 10:30 Will this kill the economics of D2C health startups? 12:57 How would we solve the problem 15:30 New LLM Paper in Nature 28:18 Audience feedback and outro Links Mentioned Cerebral Pushed ADHD Prescriptions And Failed To Report Data Breach…

Numan have raised $70M+ and are set to become the biggest men's digital health startup, ever. Here's how. From their eccentric Founder.0:00 Intro0:42 Valuation1:46 Lessons from Calm.com4:49 Raising aggressively 7:35 Successful entrepreneurs are not hyper intelligent10:38 When to quit14:43 The Social R Number18:14 Being nice gets you nowhere22:24 Nu…

0:00 Intro 0:18 Ali Parsa's Immigrant Story 1:57 Picking a Problem That Was Too Big 4:15 The Supply Induced Demand Problem 5:55 The Unit Economics Problem 7:37 The Misaligned Incentives Problem 10:11 The Friction Problem 12:06 The First Mover Disadvantage 13:30 Raising Too Much Money 14:55 The SPAC Problem 17:40 The Pig With Lipstick Problem 22:07 …

0:00 Intro 0:38 VC Dirty Money (LP Sources) 8:30 Power Dynamics Founder vs VC 12:56 Trillion $ Alzheimer's Opportunity 14:26 Eli Lily's New Alzheimer's Blockbuster (?) Donanemab 19:01 More Issues with Donanemab Phase III Results 21:48 Will Anyone Pay for Donanemab? 24:13 Donanemab Side Effects 27:15 Startup Opportunities in Alzheimer's 31:34 Outro …

Papers Mentioned— ChatGPT better + more empathetic than human doctors (JAMA Int Med Paper): https://jamanetwork.com/journals/jamainternalmedicine/fullarticle/2804309 Detecting eye disease using AI (Nature Biomedical Engineering): https://www.nature.com/articles/s41551-022-00867-5 Predicting dementia using LLMs (PLOS Digital Health): https://pubmed.…

0:00 Intro 0:32 Why are VCs so unhappy? 2:18 What’s hard about being a VC? 3:56 Hustle culture, FOMO, always-on culture in VC 9:54 Is it ever easy to become rich? 12:22 It’s time to build in healthcare 15:31 Why is healthcare so hard for big tech? 17:31 Reasons why healthcare is easier than you think 21:04 Imposter syndrome for tech people entering…

Martin Shkreli is an American Investor, Pharmaceutical Executive and Hedge Fund Manager who became the most hated man in America in 2015 when he obtained the drug Daraprim and increased its price from $13.50 a pill, to $750 overnight. 0:00 Intro 1:56 The Big Short 8:04 How to price a drug 20:01 Should we price drugs like iPhones 25:36 Pharma's dirt…

Dr Ben Maruthappu is the the Co-founder and CEO of Cera Care; a digitally-enabled social care company which has raised over $400M dollars. He was made a Member of the Order of the British Empire in 2020. 0:00 Intro 0:47 Ben's story 6:10 How to have good ideas, at the right time 12:14 Good decisions Ben made with Cera to scale 21:07 Is the US greene…

Dr Ala Alenazi is a TechBio Investor at Ascension and holds a PhD in Molecular Genetics from Cambridge University — she describes herself as a recovering scientist with extreme FOMO. 0:00 Intro 0:47 Being bombastic 3:32 Do PhDs make good VC investors? 10:38 How much of VC is luck? 12:47 Network building in VC 19:16 Getting deal flow 22:15 How to as…

0:00 Intro 0:54 Is AI Too Powerful? 17:59 Outlive, Peter Attia's New Longevity Bible 45:16 Why Are Americans Dying So Young? Joined by: Dr Adam Bataineh: Longevity doctor and Co-founder Span Health (acquired by EightSleep). Dr Imran Mahmud: Investor, Oxford-trained doctor, ex-Mckinsey and Co-founder of NYE Health. Dr Mustafa Sultan: Creator of Big …

Dr John Whyte is the Chief Medical Officer of WebMD, he’s also worked at Director level at the FDA and was also Chief Medical Expert at the Discovery Channel. 0:00 Intro 0:54 Anxiety as a content creator 2:33 Why should executives think like physicians? 7:23 Decision-making with limited information 10:47 Bayesian reasoning 12:57 Risk, acuity and st…

0:00 Intro 1:00 AI drug development 7:04 Big picture impact of AI drug development 9:14 Counterintuitive facts about drug development 11:06 Why can't we just make novel drugs with AI? Biology is hard 19:06 Microsoft's GPT-4 healthcare play 26:48 The hardest thing about health startups 31:49 Outro Joined by: Dr Adam Bataineh: Longevity doctor and Co…

Dr Shivdev Rao is a Cardiologist and CEO/Co-founder of Abridge, who have raised over $22M. Think of Abridge like an Alexa or Siri (or other voice assistant) that sits there whilst the physician and patient talk. Instead of the physician writing notes during the consult, or staying late and charting — Abridge listens to the conversation and writes u…

0:00 Intro 1:27 Semaglutide (Wegovy) lowdown, use in longevity clinics 6:38 Is a 'pill for everything' a bad thing? 10:39 What's going to happen to all the DTC weight loss startups? 13:37 Is Semaglutide a TikTok conspiracy by big pharma? 14:55 The new alcohol-free alcohol, GABA 21:07 Where are all the big UK healthtech exits? 24:16 US investors/ent…

0:00 Intro 1:09 David Sinclair's New Startup 11:25 ChatGPT for Drug Development 28:32 Transhumanist Gene Editing to Sleep Less 37:38 Banter/Audience Feedback Dr Adam Bataineh: Longevity doctor and Co-founder Span Health (acquired by EightSleep). Dr Imran Mahmud: Investor, Oxford-trained doctor, ex-Mckinsey and Co-founder of NYE Health. Dr Mustafa S…

Dr Ignacio Medrano is the Founder of Savana (raised $44M dollars with over 100 employees). They use AI to unlock all the value out of clinical records and produce real world evidence. 0:00 Intro 0:34 Ignacio's story 1:30 Learnings from Neurology -> Entrepreneurship 3:27 How to build good health products/services 5:03 Downsides of being a doctor in …

Dr Stephanie Eltz is a Trauma Surgeon and CEO and Co-founder of Doctify, which is basically Yelp/Trustpilot for Doctors. They’ve raised >£22M dollar in funding to date. 0:00 Intro 0:41 Story 2:34 Motivations 3:47 Building Doctify 8:25 Why do you have grit? Early childhood 9:21 Are patient reviews good measures of a doctor? 13:53 There is no growth …

Jason Foster is the CEO of Ori Biotech; a cell and gene therapy company who have raised $139M in funding. He also sits on the boards of companies like GripAble, Credentially, and Auxita — and is an active angel investor. 0:00 Intro 0:34 Jason's story 5:31 What was your goal? 6:39 When did you make it? 8:31 Taking calculated risks in life 10:48 Crea…

Dr Adam Bataineh is a Longevity Doctor and Founder of Span Health (acquired by EightSleep). 0:00 Intro 0:15 Bryan Johnson's Blueprint Program 12:32 Spotify's Daniel Ek Enters Healthcare 22:27 VitaDAO Raises $4.1 (from Pfizer, Balaji Srinivasan...)

Morgan Cheatham is Vice President at Bessemer Ventures and an MD Student at Brown. He was Forbes30u30 for Venture Capital. Morgan is a super smart guy who has lots of interesting theses and billion dollar ideas in health and life sciences, including ones in generative AI and biosecurity. We also spend lot of time talking about relationship-building…

Dr Adam Bataineh is a Longevity Doctor and Founder of Span Health (acquired by EightSleep). We discuss: 0:00 David Sinclair's New Ageing Paper — Legit? 15:52 Amazon RxPass — All Hype? 23:37 Metformin is San Francisco's New Birth Control 30:58 Decline in Disruptive Science — Why? Links David Sinclair's Paper: https://www.cell.com/cell/fulltext/S0092…

New series. We brainstorm billion $ health ideas. Dr Chris Lovejoy is a Cambridge-trained Medical Doctor, Startup Founder and Data Scientist specialising in medical AI and health informatics. He has an IQ of between 4000–5000. Find out what he's working on at www.chrislovejoy.me. 0:00 Intro 0:10 Generative AI 28:55 DTC Weight Loss Clinics 45:27 Cro…

Dr Anas Nader is the CEO and Co-founder of Patchwork Health; an end-to-end workforce solution which helps health systems tackle the staffing crisis. They have raised over $30M. 0:00 Intro 0:29 Why Anas has more employees than WhatsApp 9:24 How to get your product into healthcare providers 12:38 Business opportunities in health-tech 15:22 Habits tha…

Tess Cosad is the Co-founder and CEO of Béa Fertility; who have raised £2.2M in an effort to democratise access to safe and affordable fertility treatment. 0:00 Intro 1:15 Lessons from PR to healthtech 2:25 Storytelling 5:29 What do others get wrong? 6:54 Does PR add value to the world? 8:01 Béa Fertility origin story 10:16 Advice on relationship-b…

Guillermo Vela is the CEO and Co-Founder of NeuScience, a VC-backed TechBio company using AI to discover novel cancer biomarkers. 0:00 Intro 0:55 Eroom's Law 5:37 Contrarian View of Cancer 15:54 AI Will Not Make Drug Discovery Fast, Better or Cheaper 26:14 Failing is Not a Good Thing 26:38 TechBio Funding 34:07 Habits He went viral, in the techbio …

Dr Ivan Beckley is the Co-Founder of Suvera Health, a Google-backed virtual clinic which has raised over £6M in funding. 0:00 Intro 0:42 Ivan's Story 5:14 Making Cash? 7:07 Building Suvera 10:19 Clinician-Product Fit 11:58 Growing 14:11 Experience of Feedback 16:56 Lessons from Google 19:47 Being Black in Tech 23:20 Further Growth 25:36 How Can Som…

Dr Daniel Kraft is a Stanford and Harvard-trained physician-scientist and inventor. He serves as faculty chair for Medicine at Singularity University, is founder and chair of Exponential Medicine and has given four TED and two TEDMED talks. He’s also the inventor of the MarrowMiner, an FDA-approved device for the minimally invasive harvest of bone …

How do you spend £16 billion to improve the world’s health? That is the job of Sir Jeremy Farrar, the Director of the Wellcome Trust. In 1936, British pharmaceutical magnate Sir Henry Wellcome left his fortune to improve the world’s health. Now Sir Jeremy must work out what to do with £16 billion over the next decade — and where to most effectively…

Dr Imran Mahmud studied Medicine at Oxford, before studying Public Health at Harvard on a Fulbright Scholarship. He then ranked first in the country entering the Ophthalmology training programme — promptly leaving and joining McKinsey. In 2018 he co-founded NYE Health, raising over £4M. He is now a startup advisor, angel investor, digital health co…

After missing out on getting into Medical School, Ahmed studied Computer Science — later completing his PhD at Cambridge University. As a student, he launched his own health AI startup — which diagnosed rashes on intimate body parts. This didn’t work out and he pivoted and launched a data AI company called Catalyst AI. This company was later acquir…

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Dr Sandeep Bansal is the Founder and CEO of Medic Bleep; a pager replacement which raised over £3M. On top of that, he recently co-founded Carebyte Health — which offers personalised on-demand healthcare to Indians. He is also Faculty at Harvard Medical School and Barts. This is a super interesting conversation in which Sandeep explains how he has …