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Careers in Discovery is your window into the world of Pharma & Biotech. Featuring interviews each week with leaders in Drug Discovery and R&D, you’ll learn about the careers of these influential figures, the work they are doing, how they got to where they are and what advice they’d give their younger selves. Brought to you by Singular: Building Brilliant Biotechs. Connect with us at: LinkedIn: https://www.linkedin.com/company/singular-biotech/ www.singular-biotech.com
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Biotech, TechBio and Life Science investors can seem a mysterious crew to those who encounter them - come behind the curtain and learn about the view from their side of the negotiating table. Tom Froggatt, CEO of Singular, shares his conversations with angel investors, VCs and others who are active in the human health sector, as they discuss the fundraising market, how they assess investments, the mistakes they see and their advice for those heading out to raise money to save the lives of pa ...
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I’m on a mission to meet as many of the world’s best CEOs as I can. I want to understand what makes them tick, what great leadership looks like from their perspective, and how they learned to be great at what they do. This started out as a solo quest, but quickly I realised I should share these conversations with the world. If you’re a CEO right now who wants to be more effective in your work, or if you have aspirations to take the top job, then CEO Sessions is the right place to be. Come an ...
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This week I’m joined by Hazel Jones, CEO of Enhanc3d Genomics. Hazel shares her journey from her early days in Biotech to leading a company at the cutting edge of 3D genomics. We explored Hazel's career path, her transition into a CEO role and her insights on leadership, the significance of networking, and balancing professional and personal life.…
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This week on Careers in Discovery, we are joined by Peter Pack, an influential figure in the biotechnology industry with a career spanning over two decades. Peter's journey has taken him from Germany to the dynamic biotech landscape of the UK, where he now operates as a strategic partner and advisor to private equity firms and startups. In our conv…
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On this episode, I chat with Jason Mellad, CEO of Start Codon, about the Biotech investment market and startup success. Jason talked about the importance of strong, adaptable teams in early-stage companies and offers plenty of practical advice on understanding the market, recognising weaknesses, and trying to continuously improve. He shared the mos…
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"Science and technology have always fascinated me, and I've always been one to challenge the status quo." This week on Careers in Discovery, we welcome Jose Munoz-Olaya, Chief Scientific Officer of Valink Therapeutics. Jose shares his journey from an eager intern to a leader in biotechnology, emphasizing the importance of mentorship and the power o…
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We first interviewed Ben Cross five years ago, when he was the Head of Functional Genomics at Horizon Discovery, and we're delighted to welcome him back to the podcast as CTO of PhoreMost, an innovative target discovery company focused on drugging the undruggable. Ben caught us up on what he's learned over the last five years, including why failing…
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Shane Hegarty is the Chief Scientific Officer of Axonis Therapeutics, a Boston-based Biotech targeting KCC2 to revive neurons and treat people suffering from neurological disorders. Shane shared with us the story of his transition from academic to Biotech entrepreneur, why communication, persistence, collaboration and focus are critical skills for …
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Maude Tessier is the Chief Business Officer at Seismic Therapeutic, the machine learning immunology company building a discovery platform centred on parallel drug development. Maude joined us on Careers in Discovery to talk about the impact of machine learning on drug development, taking control of her career by literally knocking on doors, balanci…
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Pam Garside is an experienced angel investor and Chair of Cambridge Angels, one of the UK's leading investor networks. On this epsiode of The Other Side of The Table, we sat down with Pam to discuss the importance of smart money, why tenacity, boldness and perserverance are critical traits for founders, and her top tips on your investment deck. Enj…
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Bill Eldridge is an experienced scientific and commercial leader, one of the founding team members of the VHH antibody company Isogenica, and now their CEO. Bill joined us to talk about his career, the huge potential that still exists within antibody discovery and the magic of seeing a 96 well ELISA plate turn blue after months of failure! Enjoy...…
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We're back on The Other Side of the Table with Lee Lindley, Investment Manager at Mercia Ventures. Lee and I got into a range of topics in this podcast, including the importance of engaging early with investors, thinking beyond your next round and why it's so critical for CEOs to get their team involved in fundraising conversations. Join us for all…
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Hanadi Jabado is the Managing Partner at Sana Capital, a fund with a brilliant mission - to heal the world. Hanadi talked to us on The Other Side of The Table about the investment philosophy behind that mission, why algorithms aren't really what matters, the key role that trust plays in effective founder-investor relationships and why the market ma…
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Now a Non-Executive at a range of leading Biotech companies including Spirea, PharmEnable, Macomics, NanoSyrinx and Elasmogen, Jane Dancer has built a highly successful career in Business Development in the sector. Jane joined us to discuss that career, how she created a portfolio of NED positions, the real value of an MBA and whether you really ne…
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Come join me and the ever-insightful Darrin Disley, founding CEO of Horizon Discovery, current Chief Exec of Mogrify and investor in more than 40 Life Sciences and Social Enterprise businesses. In this episode, we got into why angel investors have different motivations, the importance of vision, why getting your cap structure right is absolutely cr…
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I'm back on The Other Side of The Table with Sean Kendall, Partner at ARCH Venture Partners. We're talking his view on the market (including my favourite quote of the series so far - "it's hard to fall out of the basement window"), why everything starts with high quality science, and how to tell if a market is "big enough" for investors.…
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This time around I'm with Mark Wyatt, Investment Director at Northern Gritstone, a group focused on realising the potential of innovation from universities across the North of England. In this episode, you'll hear about the importance of purpose to investors, what the due diligence process is really about and why you shouldn't be afraid to show the…
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This time around on The Other Side of The Table, come with me to meet Uzma Choudry, Biotech/TechBio investment lead at Octopus Ventures. Uzma built Octopus' TechBio desk and is an active investor and board member at several Biotech and TechBio companies - if you've spent any time on the UK Bio networking scene, you may well have come across her. Th…
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Next up on The Other Side of The Table, I'm joined by Gian Seehra. Gian founded two successful Biotech companies, raising c. $16m along the way, before heading into the world of VC. During his time at QVentures and Octopus Ventures, he invested into Healthtech and Life Sciences companies, and now runs a business helping Seed to Series B founders se…
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On this first episode of The Other Side of the Table, I'm with Jason Foster. Jason is a seasoned entrepreneur, investor and Biotech CEO with an amazing track record on both sides of the funding table, including a very impressive $100m Series B with his current company, Ori Biotech. His insight into the drivers of the current fundraising climate and…
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"I see all the other element of my current role - the leadership, management and mentoring - as enabling the science." Samantha Bailey-Bucktrout is the Senior Vice President of Research at Akamis Bio, a company harnessing the power of tumour gene therapy in the fight against cancer. Samantha talked to us about her career in cancer immunotherapy, wh…
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"You can learn corporate finance. You can do Excel modelling. You can read books on negotiation. But I strongly believe that Business Development is an art, and it's something that you can only really learn by doing." Beverley Carr is the Chief Business & Operating Officer of Amphista Therapeutics, a company re-engineering TPD therapies to tackle c…
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"I realised that drug development was much more than just research. There's a huge amount of work beyond coming up with a molecule, but research scientists just don't get exposed to it." Janette Thomas has built a career from Researcher to Project Manager, Operations Director and now CEO of Five Alarm Bio, a company focused on novel approaches to a…
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"If you've got into science because science itself motivates you, try and stay with it. Do other things too, learn what you need to, but be careful not to leave that science behind." Dan Williams is the CEO of SynaptixBio, a company dedicated to developing lifesaving therapies for severe leukodystrophies. Dan joined us to talk about the challenges …
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"Taking a vaccine from concept and early stage data through to a licensed product that you're putting into millions of people takes 10-15 years on average, but it was done in 10 months. So how did we manage to acheive that? Nobody wanted to be stuck in lockdown forever and so everyone really focused on coming together - a combination of industry, g…
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"Whatever opportunity arises, it may not be on the path that you think you should be on, but it will bring value. You have to do your best to identify what that value is. So keep an open mind about opportunities - there's sometimes value in applying for something that you only have 30% of the requirements for." Orla Cunningham is the Chief Scientif…
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"LinkedIn is like the professional Instagram. It looks like people's careers were so easy, mapped out and planned. It doesn't tell of the difficult decisions, the failures, the challenges, the dead ends and having to start again." Rebecca Godfrey is the Chief Operating Officer of ExpressionEdits and the author of "The Leadership Vaccine". Rebecca t…
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"Cancer drugs only started working once we realised that we actually had to measure what was going on in the tumour and match them appropriately [to patients]...we're just on the cusp of that approach being accepted in neuroscience." Jenny Barnett is the CEO of Monument Therapeutics, a Biotech company using precision medicine approaches to develop …
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"The most important thing is to enjoy what you're doing. If you're in the lab and enjoying your research, that's great. Keep enjoying it and you'll probably delivery well. If you want to keep focusing on research, you can, and if you want to experience different things, you'll have created the opportunity to do so." Paul Thompson is the Chief Scien…
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"Look at oncology 50 years ago. With huge amounts of investment we now think that most form of cancer are treatable. With investment, understanding, time and research that's possible in neurodegeneration - that you can not just slow or even stop but reverse and repair it." Andy Whiting is the CEO of Nevrargenics, a Biotech company spun out of his r…
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"[As a CEO] you have to force yourself to think about what's happening in your business - and that doesn't mean doing 8 hours of Zoom calls a day. Just as it's the gaps between the notes that make music, it's the gaps between the timetable acitvities that enable strategic thinking." Ross Breckenridge is the CEO of Arjuna Therapeutics, a Biotech com…
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"Drug discovery is one of the biggest miracles we can accomplish. You're taking something that didn't exist before, then putting it into the most complex system we know of, hoping that it does one specific thing and not a bunch of other bad things. The fact that it ever works is a miracle." Jonathan Steckbeck is the CEO of Peptilogics, a Biotech co…
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"Get experience, talk to people who are doing it, go to networking sessions and interact with business owners - we've all got a story to tell and most are happy to share advice." Steve Trim is the founder and Chief Scientific Officer of Venomtech, a truly unique company that helps Biotech researchers to work with venom-based assays. Steve talked to…
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"Embrace being uncomfortable. It's easy to say, I know, but go out there and don't be afraid. It will be challenging, it will make you anxious but if you don't try, [what you want] won't happen." Tomas Dias is the Chief Technology Officer at Mursla, a Biotech company using extracellular vesicles to develop next-generation liquid biopsy tests in ser…
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"As a PhD, you're very focused on the question and the process of how you get things done. Our focus [as a Biotech company] is on what impact we want to have, where we're going and the key questions that our partners are trying to answer." Samantha Dale Strasser is the Chief Scientific Officer of Pepper Bio, the world's first transomic analysis com…
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"It comes down to [the question], 'Why are you here?'. We looked at this project and thought, if we do this and it works, then we have a therapy that could prevent people from progressing down the inevitable slide into insulin dependence, with all the long term impacts that implies. And that would be a really worthwhile course to take." Nara Dauben…
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"Don't think that just because you've done a Biology or Chemistry degree, this is your path forever....I didn't become an entrepreneur until the age of 42. Your [career] path isn't fixed." Richard Weaver is a consultant to Biotech companies on their drug development programmes, specialising in DMPK. Before becoming a consultant, Rich was the founde…
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"Anybody can be a pair of hands, follow a protocol and do what they're told. If you want more than that, if you want to be a pair of hands with a brain, then you have to think differently." Nuno Madeira do Ó is the CEO of Reflection Therapeutics, a Biotech company harnessing the potential of Tregs to treat inflammatory diseases. Nuno shared the sto…
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"We are in such an exciting time in Life Sciences...if you have an idea, go for it, because there's a lot of VC money out there...and the appetite to invest early has improved, so it's the right time to speak to investors about potential ideas." Leigh Brody is an entrepreneur, executive and now venture investor at AlbionVC, where she oversees the U…
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"Join a young company. If you're employee number 10, you're 10% of the business as opposed to 1% in a 100 person company. You will learn way more just by osmosis....if you're curious and ask questions." Samuel Woodhouse is the VP of Operations at CoSyne Therapeutics, a technology-driven drug discovery company on a mission to reinvent Pharma from th…
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"In the first few years [of your career], what's really important is to establish yourself. You learn a certain skillset in academia...the next thing is to really apply that in the context of a drug discovery project....if you develop a proven track record as a good scientist, good things will happen." Roland Burli is the Vice President of Drug Dis…
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"[If you receive negative feedback] analyse it in a constructive way, then take away the good points that will help you to move forward. Outside of that, just move on." Sree Vadlamudi is the Vice President of Business Development for the EU and Rest of World at Iktos, a company using AI to expedite drug discovery. We talked to Sree about his career…
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"Scientists work on things they can't see and that probably will never work - but they keep going. Resilience is so important in this career." Valentino Parravicini is the Chief Scientific Officer of Oxford Cannabinoid Technologies, a company harnessing the power of the endocannabinoid system to treat severe, chronic pain. Valentino joined us to ta…
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"Academic freedom is a little like french fries - they're not really French, and it's not really freedom." Yaniv Erlich is the CEO of Eleven Therapeutics, a global Biotech startup turning RNA drug development into a programmable process. Yaniv talked to us about his journey from academia to the military and into Biotech, meeting Bill Gates and the …
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"I think of raising money as making a sale...instead of selling a house, I'm selling you my dream. First, you have to target the people you will sell to, then you create awareness and establish rapport, without selling....it's an ongoing process that can take years." Marcelo Bravo is the CEO of OxVax, a Biotech company building a next generation de…
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"Not everything is driven by innovation. It's actually timing that proves to be more important than anything else." Farid Khan is the CEO and founder of PharmaKure, a Biotech company taking a novel approach to treating complex neurological diseases. Farid talked us through his fascinating entrepreneurial career, along with the opportunity presented…
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"I've always learned the most when things were the most difficult, and I try to remind myself of that when I'm in the middle of something that feels really challenging. They're the most satisfying situations when you solve them." Clare Jones is the Chief Scientific Officer of Talisman Therapeutics, a Biotech company committed to revolutionising the…
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