A podcast on medicine, oncology, & health policy. Host: Vinay Prasad, MD MPH from University of California San Francisco. Tweet your feedback to @Plenary_Session or e-mail plenarysessionpodcast@gmail.com
Expert insight on health, performance, longevity, critical thinking, and pursuing excellence. Dr. Peter Attia (Stanford/Hopkins/NIH-trained MD) talks with leaders in their fields.
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3.47 COVID-19 Vaccine Results, Messaging on a Patient Level, & Schools with Dr. Monica Gandhi
56:40
56:40
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Today we interview Dr. Monica Gandhi, Associate Division Chief of the Division of HIV, Infectious Diseases, and Global Medicine at UCSF/ San Francisco General Hospital, and medical director of the HIV Clinic at SFGH, on COVID-19 interventions. We talk about results from the vaccine studies and how vaccination is perceived by the public. We talk abo…
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The Peter Attia Drive


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#151 - Alex Hutchinson, Ph.D.: Translating the science of endurance and extreme human performance
2:13:44
2:13:44
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Alex Hutchinson is a sports science journalist, author of the book Endure—which explores the science of endurance and the real limits of human performance—and former competitive runner for the Canadian national team. In this episode, Alex tells the story of his “aha moment” during a meaningless track meet that catapulted his running career and seed…
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3.46 COVID-19 Risk, Cases, and Transmission in K-12 Schools with Dr. Tracy Høeg
46:34
46:34
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Today we interview Dr. Tracy Høeg on her new paper and her ongoing research into COVID-19 transmission in K-12 schools in Wisconsin, USA. Dr. Høeg is an epidemiologist and an interventional sports and medicine spine specialist at Northern California Orthopaedic Associates. Her paper is titled "COVID-19 Cases and Transmission in 17 K-12 Schools - Wo…
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3.45 USMLE Steps, Residency Match, & M.D. vs D.O. with Dr. Bryan Carmody
1:28:17
1:28:17
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1:28:17
On today's episode we interview Dr. Bryan Carmody, commonly known as the Sheriff of Sodium. He's a pediatric nephrologist at Children's Hospital of the King's Daughters in Virginia. We talk with him about the USMLE Steps (Step 1, Step 2, and Step 2 CS), their usefulness, their origins, and how to reform them. We also break down and discuss the inne…
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The Peter Attia Drive


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#150 - Senator Bill Frist, M.D.: A modern Renaissance man's journey through science, politics, and business
2:23:38
2:23:38
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2:23:38
Bill Frist is a nationally acclaimed heart and lung transplant surgeon, former U.S. Senate Majority Leader, and is actively engaged in health policy and education reform. In this episode, Bill takes us through his long and varied career in medicine, politics, and business, which includes establishing the organ transplantation program at Vanderbilt …
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3.44 The Role of Philosophy, COVID-19 Policy, and COVID-19 Exceptionalism with Dr. Alex John London
1:17:59
1:17:59
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1:17:59
Today we sit down with Dr. Alex John London, the Clara L. West Professor of Ethics and Philosophy and Director of the Center for Ethics and Policy at Carnegie Mellon University, to discuss the role of philosophy, COVID-19 exceptionalism, and various aspects of COVID-19 health policy including masking, vaccination, and schools.Back us on Patreon! ww…
On today’s episode we review the findings of the Beat AML study as published in Nature Medicine in an article titled “Precision medicine treatment in acute myeloid leukemia using prospective genomic profiling: feasibility and preliminary efficacy of the Beat AML Master Trial”. Beat AML: doi.org/10.1038/s41591-020-1089-8Back us on Patreon! www.patre…
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The Peter Attia Drive


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#149 - AMA #20: Simplifying the complexities of insulin resistance: how it's measured, how it manifests in the muscle and liver, and what we can do about it
23:07
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In this “Ask Me Anything” (AMA) episode, Peter and Bob discuss all things related to insulin resistance by revisiting the important points made in the fascinating, yet quite technical, episode of The Drive with Gerald Shulman. They devote the entire discussion to understanding the condition known as insulin resistance, how it’s measured, how it man…
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3.42 Overdiagnosis and Cutaneous Melanoma Diagnoses with Dr. Adewole Adamson and Dr. Benjamin Mazer
1:06:13
1:06:13
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For today's episode, we sit down with Drs. Ade Adamson of the University of Texas at Austin Dell Medical School and Ben Mazer of Johns Hopkins Hospital to discuss their new paper out now in the New England Journal of Medicine titled "The Rapid Rise in Cutaneous Melanoma Diagnoses". It's one of the best papers you'll read all year.Melanoma Diagnoses…
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The Peter Attia Drive


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#148 - Richard Miller, M.D., Ph.D.: The gold standard for testing longevity drugs: the Interventions Testing Program
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2:14:14
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Richard Miller is a professor of pathology and the Director of the Center for Aging Research at the University of Michigan. He is one of the architects of the NIA-funded Interventions Testing Programs (ITPs) animal study test protocol. In this episode, Rich goes through the results of the long list of molecules tested by the ITP—including rapamycin…
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3.41 Building a Meta-Research Career and Constructing COVID-19 Health Policy with Dr. John Ioannidis
1:59:06
1:59:06
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1:59:06
For today's special episode, we sat down with Dr. John Ioannidis of Stanford University for an outdoor in-person interview. We take a deep dive into his work from 2000 all the way up to present day: his career from 2000 to 2010, his move to Stanford, and his work on COVID-19. We take a deep dive into his work on COVID-19: IFR, shielding ratio, the …
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3.40 COVID-19 Vaccines, Origin of SARS-CoV-2, and Pandemic Mitigation with Prof Francois Balloux
56:59
56:59
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56:59
On today's episode we're joined by geneticist Dr. Francois Balloux, the Director of the University College London Genetics Institute and professor of computational systems biology, on pandemic mitigation, SARS-CoV-2 variants, how news and social media amplify fear over fact, opening schools, lethality and risk, the origin of SARS-CoV-2, COVID-19 va…
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3.39 Public Health Messaging on COVID-19 with Drs. Julia Marcus and Stefan Baral
1:08:32
1:08:32
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1:08:32
On today's episode we feature an in-depth interview with Dr. Julia Marcus (Associate Professor at Harvard Medical School) and Dr. Stefan Baral (Associate Professor at Johns Hopkins Bloomberg School of Public Health), two infectious disease epidemiologists, on public health messaging around COVID-19 -- what we're getting right and where we're going …
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The Peter Attia Drive


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#147 - Hussein Yassine, M.D.: Deep dive into the “Alzheimer’s gene” (APOE), brain health, and omega-3s
2:06:19
2:06:19
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Hussein Yassine is a physician and researcher who studies brain lipid utilization in the context of finding preventative measures for cognitive impairment, specifically Alzheimer’s disease (AD). In my conversation with Hussein, we begin with a fundamental coursework in brain biology—including its architecture and energy systems. We go on to discuss…
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3.38 Oncology During COVID-19 & RCTs from Low- vs High-Income Countries with Dr. Christopher Booth
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56:03
On today's episode we sit down with Dr. Chris Booth of Queen's University in Kingston, Ontario, Canada to discuss his new paper out now in JAMA Oncology titled "An Analysis of Contemporary Oncology Randomized Clinical Trials From Low/Middle-Income vs High-Income Countries". We also talk about how COVID-19 has affected oncology research. We touch, t…
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3.37 Skepticism, COVID-19, and Debating Science in the Era of Trade-Offs with Jacob Hale Russell
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1:33:03
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1:33:03
On today's episode we are joined by Jacob Hale Russell, an Associate Professor of Law at Rutgers Law School. We discuss his forthcoming book on skepticism, elites, and expertise, as well as his article out now on StatNews about the myth of COVID-19 denial. We talk about anti-intellectualism and how science ought to be debated in the era of trade-of…
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The Peter Attia Drive


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#146 - Guy Winch, Ph.D.: Emotional first aid and how to treat psychological injuries
1:57:29
1:57:29
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Guy Winch is a psychologist, author, and co-host of the Dear Therapist podcast. In this episode, Guy speaks to the commonality of the human condition with relatable stories from his decades of therapy sessions as well as his own experience with incessant rumination in the early days of his private practice. He shares insights on what he sees as an …
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3.36 Sustainable Ex-Vivo Seafood with Dr. Arye Elfenbein
46:52
46:52
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On today's episode we sit down with Dr. Arye Elfenbein, a cardiologist and "doctorpreneur " to interview him on the bio-tech company he recently co-founded: Wildtype. Wildtype manufactures ex-vivo fish meat for human consumption in fulfillment of their mission to create the cleanest, most sustainable seafood.Back us on Patreon! www.patreon.com/plen…
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3.35 The Secrets of Vermont in Taming the COVID-19 Pandemic with Anne Sosin
36:02
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Today we interview Anne Sosin of Dartmouth College on public health policy in Vermont and how the state has uniquely tamed the COVID-19 pandemic.Back us on Patreon! www.patreon.com/plenarysessionCheck out our YouTube channel: www.youtube.com/channel/UCUibd0E2kdF9N9e-EmIbUewBy Plenary Session
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#145 - AMA #19: Deep dive on Zone 2 training, magnesium supplementation, and how to engage with your doctor
17:33
17:33
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In this “Ask Me Anything” (AMA) episode, Peter and Bob take a deep dive into zone 2 training. They begin with a detailed definition of zone 2 and continue by discussing the importance of adding it to your exercise regimen. They talk about how to program zone 2 training, including intensity, frequency, and duration, and metrics for tracking improvem…
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3.34 COVID-19 From a Philosopher's Point of View with Dr. Matthew Smith
1:07:56
1:07:56
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Today we sit down with Dr. Matthew Smith, an associate professor in the Northeastern University Department of Philosophy and Religion, for a far-ranging discussion on COVID-19 from a philosopher's point of view.Back us on Patreon! www.patreon.com/plenarysessionCheck out our YouTube channel: www.youtube.com/channel/UCUibd0E2kdF9N9e-EmIbUew…
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3.33 Hematologic Malignancies and Transplantation with Dr. Aaron Goodman
47:47
47:47
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Today we are joined by Dr. Aaron Goodman, an Assistant Clinical Professor at the University of California San Diego, who talks with us about hematologic malignancies, transplantation, and our new paper out now in Blood titled "Persistent Challenges with Treating Multiple Myeloma Early".Persistent Challenges: doi.org/10.1182/blood.2020009752Back us …
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The Peter Attia Drive


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#144 - Phil Maffetone: Optimizing health and performance through maximal aerobic function
1:22:12
1:22:12
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1:22:12
Phil Maffetone is an author, health practitioner, and coach with decades of experience helping everyone from amateurs to world-class athletes optimize their health and performance. In this episode, Phil explains the importance of developing the aerobic system, defines maximum aerobic function (MAF), and explains how to determine your MAF heart rate…
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3.32 Publishing Original Thought in Medical Journals with Dr. Stephen Bradley
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52:09
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52:09
Today we talk with Dr. Stephen Bradley, a General Practitioner and Clinical Research Fellow at the University of Leeds, on publishing in medical journals -- peer review, editorial practices, anti-intellectualism, and more!Notes on Nationalism: www.orwellfoundation.com/the-orwell-foundation/orwell/essays-and-other-works/notes-on-nationalism/Back us …
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3.31 Random Thoughts on Visiting Hospital Patients During COVID-19 and Norman Wang's Lawsuit
40:44
40:44
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Today we have for you an episode of random thoughts. We talk over the ramifications of the strict COVID-19 policy that prevents people from visiting their dying loved ones in the hospital. We also talk more about Norman Wang and his surrounding controversy given the recent lawsuit the Center for Individual Rights has filed against the University of…
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3.30 Benefit and Risk of SpaceOAR with Dr. William Hall
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41:17
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On today's episode we interview Dr. Bill Hall, Associate Professor of Radiation Oncology and Surgery at Medical College of Wisconsin, on our new paper out now in The Lancet Oncology titled "Considering benefit and risk before routinely recommending SpaceOAR".SpaceOAR: doi.org/10.1016/S1470-2045(20)30639-2Back us on Patreon! www.patreon.com/plenarys…
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The Peter Attia Drive


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#143 - John Ioannidis, M.D., D.Sc.: Why most biomedical research is flawed, and how to improve it
1:52:01
1:52:01
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John Ioannidis is a physician, scientist, writer, and a Stanford University professor who studies scientific research itself, a process known as meta-research. In this episode, John discusses his staggering finding that the majority of published research is actually incorrect. Using nutritional epidemiology as the poster child for irreproducible fi…
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3.29 Censorship in Medicine with Jonathan Darrow
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1:01:30
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On today's episode we discuss censorship in medicine in all its forms with legal expert Jonathan Darrow, an Assistant Professor at Harvard Medical School.Back us on Patreon! www.patreon.com/plenarysessionCheck out our YouTube channel: www.youtube.com/channel/UCUibd0E2kdF9N9e-EmIbUewBy Plenary Session
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3.28 Exploring the History of Medicine with Dr. Adam Rodman, host of Bedside Rounds
1:13:36
1:13:36
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On today's episode we talk podcasting and the history of medicine with Dr. Adam Rodman, the creator and host of the wildly popular podcast Bedside Rounds, and a hospitalist at the Beth Israel Deaconess Medical Center.Back us on Patreon! www.patreon.com/plenarysessionCheck out our YouTube channel: www.youtube.com/channel/UCUibd0E2kdF9N9e-EmIbUew…
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#142 - Robert Abbott: The Bobby Knight story—a cautionary tale of unchecked anger, ego, and winning at all costs
2:14:25
2:14:25
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Robert Abbott is a six-time Emmy award winner and the director of “The Last Days of Knight,” the behind-the-scenes documentary of legendary coach Bobby Knight, and the events that led to his termination from Indiana University. In this episode, Robert takes us through his investigative journey, which revealed cautionary tales of a winning at all co…