How can we, humans, look at our relationship to nature differently? In season three of Going Wild, on top of stories about animals, we invite you to journey through the entire ecological web — from the tiniest of life forms to apex predators — alongside the scientists, activists and adventurers who study it. Wildlife biologist and host Dr. Rae Wynn-Grant has been studying wild animals in their natural habitats all over the world for years. Our award-winning podcast takes you inside the hidde ...
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EP 111: Combining human and machine intelligence in protein engineering with Dr. James Field, CEO of LabGenius
MP3•Episode home
Manage episode 382876612 series 2631947
Content provided by Sano Genetics. All podcast content including episodes, graphics, and podcast descriptions are uploaded and provided directly by Sano Genetics or their podcast platform partner. If you believe someone is using your copyrighted work without your permission, you can follow the process outlined here https://player.fm/legal.
In this episode of The Genetics Podcast, we welcome Dr. James Field, founder and CEO of LabGenius. Join us as we delve into LabGenius' cutting-edge approach that utilises machine learning, artificial intelligence, and sophisticated robotics to advance antibody discovery and drug development. As a bonus, learn about James’ path from scientist to CEO, and how he created LabGenius.
Timestamps:
00:00 Introduction
01:04 The genesis of LabGenius: protein engineering
04:06 Progressing from human intuition and rules-of-thumb to a mathematically-driven approach to protein synthesis
05:24 Redefining the relationship between human and machine
08:38 Multi-dimensional optimisation: an iterative machine learning approach to design and test various molecules
11:20 The LabGenius Process to developing antibodies: sequencing, testing mammalian expression, and functional cell-based assays
12:50 The relative scalability of functional cell-based assays
14:30 How LabGenius is tackling the bottlenecks in finding antibodies to cure cancer
15:52 Applying protein engineering beyond antibodies to enzymes and other biological molecules
18:12 The challenges in scaling clinical trials and the choice to engage with partners
19:24 James’ shift from scientist to CEO: Overcoming the challenges of fundraising and finding smart investors who share your vision
24:40 James’ entrepreneurial spirit: wanting to build something that is worth the tough journey
26:10 The biggest challenges to creating LabGenius and lessons learned from starting a company
29:00 Navigating the complexities of partnering with large pharma and biotech companies
30:42 Novel technologies on the horizon that redefine what it means to be healthy
32:48 Future Frontiers: The potential for in-silico models in advancing drug discovery
34:58 Closing Remarks
167 episodes
MP3•Episode home
Manage episode 382876612 series 2631947
Content provided by Sano Genetics. All podcast content including episodes, graphics, and podcast descriptions are uploaded and provided directly by Sano Genetics or their podcast platform partner. If you believe someone is using your copyrighted work without your permission, you can follow the process outlined here https://player.fm/legal.
In this episode of The Genetics Podcast, we welcome Dr. James Field, founder and CEO of LabGenius. Join us as we delve into LabGenius' cutting-edge approach that utilises machine learning, artificial intelligence, and sophisticated robotics to advance antibody discovery and drug development. As a bonus, learn about James’ path from scientist to CEO, and how he created LabGenius.
Timestamps:
00:00 Introduction
01:04 The genesis of LabGenius: protein engineering
04:06 Progressing from human intuition and rules-of-thumb to a mathematically-driven approach to protein synthesis
05:24 Redefining the relationship between human and machine
08:38 Multi-dimensional optimisation: an iterative machine learning approach to design and test various molecules
11:20 The LabGenius Process to developing antibodies: sequencing, testing mammalian expression, and functional cell-based assays
12:50 The relative scalability of functional cell-based assays
14:30 How LabGenius is tackling the bottlenecks in finding antibodies to cure cancer
15:52 Applying protein engineering beyond antibodies to enzymes and other biological molecules
18:12 The challenges in scaling clinical trials and the choice to engage with partners
19:24 James’ shift from scientist to CEO: Overcoming the challenges of fundraising and finding smart investors who share your vision
24:40 James’ entrepreneurial spirit: wanting to build something that is worth the tough journey
26:10 The biggest challenges to creating LabGenius and lessons learned from starting a company
29:00 Navigating the complexities of partnering with large pharma and biotech companies
30:42 Novel technologies on the horizon that redefine what it means to be healthy
32:48 Future Frontiers: The potential for in-silico models in advancing drug discovery
34:58 Closing Remarks
167 episodes
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