How can we, humans, look at our relationship to nature differently? In season three of Going Wild, on top of stories about animals, we invite you to journey through the entire ecological web — from the tiniest of life forms to apex predators — alongside the scientists, activists and adventurers who study it. Wildlife biologist and host Dr. Rae Wynn-Grant has been studying wild animals in their natural habitats all over the world for years. Our award-winning podcast takes you inside the hidde ...
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EP 138: Personalised medicine using microbiome models with Dr. Almut Heinken
MP3•Episode home
Manage episode 422155723 series 2631947
Content provided by Sano Genetics. All podcast content including episodes, graphics, and podcast descriptions are uploaded and provided directly by Sano Genetics or their podcast platform partner. If you believe someone is using your copyrighted work without your permission, you can follow the process outlined here https://player.fm/legal.
0:00 Introduction
1:45 Almut’s research experience, including two recent publications on genome-scale metabolic reconstruction human microorganisms
- Genome-scale metabolic reconstruction of 7,302 human microorganisms for personalized medicine
- APOLLO: A genome-scale metabolic reconstruction resource of 247,092 diverse human microbes spanning multiple continents, age groups, and body sites
8:00 Implications for personalised medicine and drug discovery using microorganisms in colorectal cancer, inflammatory bowel disease, ulcerative colitis, and more
14:30 Using metabolite and microbiome models to predict the effectiveness of medications
18:00 Differences in microbial communities between various ethnicities, nationalities, and races
24:00 Understanding microbiome community models with the goal of informing drug discovery
26:30 The interplay between diet, the microbiome, and nervous system
28:00 How to use predictive models to understand the diet-microbiome relationship
36:00 Upcoming projects studying the gut microbiome and epigenetics
38:30 Comparing a vaginal birth to a caesarean section on the child’s microbial immunity
40:00 Explaining the cause of heterogeneous differences in monogenic diseases
45:00 Closing remarks
Please consider rating and reviewing us on your chosen podcast listening platform!
167 episodes
MP3•Episode home
Manage episode 422155723 series 2631947
Content provided by Sano Genetics. All podcast content including episodes, graphics, and podcast descriptions are uploaded and provided directly by Sano Genetics or their podcast platform partner. If you believe someone is using your copyrighted work without your permission, you can follow the process outlined here https://player.fm/legal.
0:00 Introduction
1:45 Almut’s research experience, including two recent publications on genome-scale metabolic reconstruction human microorganisms
- Genome-scale metabolic reconstruction of 7,302 human microorganisms for personalized medicine
- APOLLO: A genome-scale metabolic reconstruction resource of 247,092 diverse human microbes spanning multiple continents, age groups, and body sites
8:00 Implications for personalised medicine and drug discovery using microorganisms in colorectal cancer, inflammatory bowel disease, ulcerative colitis, and more
14:30 Using metabolite and microbiome models to predict the effectiveness of medications
18:00 Differences in microbial communities between various ethnicities, nationalities, and races
24:00 Understanding microbiome community models with the goal of informing drug discovery
26:30 The interplay between diet, the microbiome, and nervous system
28:00 How to use predictive models to understand the diet-microbiome relationship
36:00 Upcoming projects studying the gut microbiome and epigenetics
38:30 Comparing a vaginal birth to a caesarean section on the child’s microbial immunity
40:00 Explaining the cause of heterogeneous differences in monogenic diseases
45:00 Closing remarks
Please consider rating and reviewing us on your chosen podcast listening platform!
167 episodes
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