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CBD and the CB1 Receptor: A Look at Allosteric Modulation with Rob Laprairie, PhD + Liz Thompson, MS | #102

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Content provided by Isn't Life Curious?. All podcast content including episodes, graphics, and podcast descriptions are uploaded and provided directly by Isn't Life Curious? or their podcast platform partner. If you believe someone is using your copyrighted work without your permission, you can follow the process outlined here https://player.fm/legal.

How does CBD affect the CB1 receptor, really?

Rob Laprairie is a cannabinoid researcher out of the University of Saskatchewan who was involved in the discovery of CBD’s allosteric binding activity on the CB1 receptor – leading to a host of speculative theories about how CBD influences the activity of THC. In this conversation, continuing our Train with Mary Jane series, we sit down with Rob and discuss his work studying the CB1 receptor to better understand how CBD and “minor” cannabinoids from Cannabis affect the body. Rob helps break down common misunderstandings about CBD’s effects, explains how our understanding of chemical receptors is evolving, and what the future of cannabinoid research may look like.

“Allosteric and orthosteric pharmacology of cannabidiol and cannabidiol-dimethylheptyl at the type 1 and type 2 cannabinoid receptors”: https://bpspubs.onlinelibrary.wiley.com/doi/full/10.1111/bph.14440

  continue reading

127 episodes

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iconShare
 
Manage episode 424462836 series 2651926
Content provided by Isn't Life Curious?. All podcast content including episodes, graphics, and podcast descriptions are uploaded and provided directly by Isn't Life Curious? or their podcast platform partner. If you believe someone is using your copyrighted work without your permission, you can follow the process outlined here https://player.fm/legal.

How does CBD affect the CB1 receptor, really?

Rob Laprairie is a cannabinoid researcher out of the University of Saskatchewan who was involved in the discovery of CBD’s allosteric binding activity on the CB1 receptor – leading to a host of speculative theories about how CBD influences the activity of THC. In this conversation, continuing our Train with Mary Jane series, we sit down with Rob and discuss his work studying the CB1 receptor to better understand how CBD and “minor” cannabinoids from Cannabis affect the body. Rob helps break down common misunderstandings about CBD’s effects, explains how our understanding of chemical receptors is evolving, and what the future of cannabinoid research may look like.

“Allosteric and orthosteric pharmacology of cannabidiol and cannabidiol-dimethylheptyl at the type 1 and type 2 cannabinoid receptors”: https://bpspubs.onlinelibrary.wiley.com/doi/full/10.1111/bph.14440

  continue reading

127 episodes

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