Episode 7: Anne Wyllie, COVID-19, The NBA And Spit Diagnostics Washed Down With A G&T! The Translational Mixer podcast

Episode 7: Anne Wyllie, COVID-19, the NBA and spit diagnostics washed down with a G&T!

4M ago 57:45

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Anne Wyllie, principal investigator at the Yale School of Public Health and pioneer of the Saliva Direct initiative, talks to JC and Andy about the potential of open and collaborative models to transform infectious disease diagnostics and pandemic preparedness.
1) The Gin & Tonic

1 cup ice cubes
2 Oz gin
~4 Oz Schweppes Tonic Water
1 slice Lime/lemon
DIRECTIONS:
Pour 2 Oz gin into your favorite glass, ideally a large goblet full of ice, as shown. Top with ~4 Oz tonic water, mix gently, and garnish with lime or lemon.

2) The Mediterranean Gin & Tonic

1 cup ice cubes
1.5 Oz Gin Mare (Spanish Gin)
0.5 Oz Dry Vermouth
0.5 Oz Sweet Vermouth
~4 Oz Fever Tree Tonic water
1 sprig Thyme
1 slice Lime/lemon

Fill your favorite glass with ice. Pour 1.5 Oz Gin Mare (Spanish gin), 0.5 Oz dry vermouth, 0.5 Oz sweet vermouth. Top with ~4 Oz Fever Tree Mediterranean Tonic and mix gently. Garnish with thyme and lime/lemon.
Sources mentioned in the podcast:
Paper comparing saliva test to nasal/nasopharyngeal test: Overmeire, Y et al. Equivalence of Saliva RT-qPCR Testing to Nasal-throat/Nasopharyngeal Swab Testing in the General Practitioner’s Setting to Detect SARS-CoV-2. J. Pediatr, Perinatol. Child Health 6, 042-053 (2022). doi: 10.26502/jppch.74050089
CDC COVID-19 testing guidelines (now including saliva)

The COVID-19 testing debacle Nat Biotechnol 38 653 (2020)

Saliva Direct and its test Emergency Use Authorization

BBC News story on kids adding soda to get false positives in COVID-19 tests

The Mixer music “Pour Me Another” courtesy of Smooth Moves!

Chapters

1. Episode 7: Anne Wyllie, COVID-19, the NBA and spit diagnostics washed down with a G&T! (00:00:00)

2. Beginnings (00:01:44)

3. The niche for saliva-based tests (00:07:40)

4. Sensitivity or selectivity? (00:10:55)

5. Location, location, location (00:13:47)

6. What kind of oversight does testing need? (00:17:27)

7. Diagnostics in low to middle income countries (00:27:20)

8. The COVID hangover (00:31:22)

9. Spit and the NBA (00:40:15)

10. Convening a community (00:44:22)

11. Anne’s alcoholic apertif (00:50:53)

9 episodes