The Big Thinking Podcast is the podcast of the Federation for the Humanities and Social Sciences, featuring some of the most interesting and innovative people in the humanities and social sciences in conversation about their research on important issues of our time.
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Congrès en Conversation - Partie III avec Aliyah Datoo
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Bienvenue au Congrès en Conversation, une série spéciale présentée par le balado Voir Grand et la Conversation Canada, dans laquelle nous invitons les chercheur.euse.s qui participent au Congrès à partager leurs recherches et leurs expériences dans le contexte de notre reponsabilité commune envers notre société, nos systèmes et notre planète. Pour …
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Congress in Conversation - Part II with Kshamta Hunter
25:21
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Welcome to Congress in Conversation, a special series presented by the Big Thinking Podcast in partnership with The Conversation Canada where we convene researchers presenting at Congress 2024 to share their research and experiences within the context of shared responsibility to our society, systems, and planet. For our second episode, our host Neh…
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Congress in Conversation - Part I with Christopher Dietzel
26:37
26:37
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Welcome to Congress in Conversation, a special series presented by the Big Thinking Podcast in partnership with The Conversation Canada where we convene researchers presenting at Congress 2024 to share their research and experiences within the context of shared responsibility to our society, systems, and planet. For this first episode, our host Neh…
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Episode 62: Josh Mandel-Brehm - CEO, CAMP4 Therapeutics
20:10
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Explore the untapped potential of RNA amplifying therapeutics with the CEO of CAMP4 Therapeutics, Josh Mandel-Brehm. We uncover the power of antisense oligonucleotides in rewriting the narrative for genetic diseases characterized by protein deficiency. Josh takes us behind the scenes of their innovative RNA Actuating Platform (RAP), a map charting …
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Episode 61: William Korinek - CEO and Co-Founder, Astrocyte Pharmaceuticals
24:20
24:20
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Embark on a journey through the neurons and synapses of brain science with William Korinek, the CEO of Astrocyte Pharmaceuticals. In a conversation that fuses the molecular intricacies of neuroprotection with the humanistic pursuit of medical advancement, Bill reveals his unique path from molecular biologist to biotech innovator. Together, we unrav…
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Episode 60: Rachel Haines - VP of Clinical Development & Operations, Rinri Therapeutics
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18:30
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By Vial
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Episode 59: Bas van der Baan - President & CEO, Lixte Biotechnology
17:32
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Join as we dive deep into the world of oncology drug development with Bas van der Baan of Lixte. Discover the inspiration behind Lixte's focus on PP2A inhibitors and how this innovative approach is poised to revolutionize cancer treatment by enhancing chemotherapy and immunotherapy responses. Bas shares insights into ongoing clinical trials, regula…
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Episode 58: Samarendra Mohanty - President & CSO, Nanoscope Therapeutics
16:36
16:36
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Dr. Samar Mohanty, president and CSO of Nanoscope Therapeutics joins us to shed light on the revolutionary gene therapy that's giving hope to individuals with retinal degenerative diseases by pioneering a treatment that can re-sensitize the retina to detect low light levels. We open the curtains on their groundbreaking multi-characteristic opsins (…
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Episode 57: Rob Etherington- CEO and President at Clene Nanomedicine
20:06
20:06
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Imagine unlocking the secrets to revitalizing the brain's energy centers and turning the tide on neurodegenerative diseases. In this episode, Rob introduces us to CNM-Au8, an oral nanotherapeutic with the potential to recharge failing mitochondria. Our discussion traverses the innovative path Clene has charted, from the drug's conception to the exc…
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Episode 56: Jason Bock- Founder and CEO at CTMC
22:28
22:28
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Step into the future as Dr. Jason Bock, founder and CEO of CTMC discusses the company's unique approach to accelerating cell therapies from development to testing, and the power of collaboration in reshaping the future of cancer treatment. Listen in as we discuss how CTMC's partnership with MD Anderson is not just technical but deeply human in natu…
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Episode 55: Alex Federation- Co-Founder at Talus Bio
15:27
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Embark on a quest to unravel the 'undruggable' genome with Alex Federation, Co-founder of Talus Bio. Explore challenges in targeting transcription factors in cancer with Talus's innovative Marmot platform. Discover potential breakthroughs in rare diseases and pediatric cancers, and glimpse into the future of studying transcription factors within li…
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Episode 54: Ahmed Hamdy- CEO at Vincerx Pharma
16:52
16:52
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Join Dr. Ahmed Hamdy, CEO of Vincerx Pharma, on a compelling journey through oncology. From co-founding Acerta Pharma to pioneering patient-centric innovations, Dr. Hamdy shares his impactful career. Explore the groundbreaking VersAptx bioconjugation platform, designed to elevate cancer therapies and uncover the delicate balance between clinical ex…
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Episode 53: Sam Clark- CEO & Founder at Terran Biosciences
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18:10
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Have you ever considered the untapped potential of abandoned drugs? Join Dr. Sam Clark to discuss how his personal drive to combat mental illness is leading to breakthroughs in treatments for neurological and psychiatric diseases. Witness how Terran is not only resurrecting discarded medications for new purposes, but also pioneering the next genera…
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Episode 52: Mark McDonough- President & CEO of ChromaCode
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Ever wondered how technology could drastically improve early detection in healthcare? Let us take you on a journey with Mark McDonough, President and CEO of ChromaCode, as we unfold the world of molecular diagnostics with a special focus on HDPCR technology. Mark, with his diverse background in the military and healthcare, brings a fresh perspectiv…
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Episode 51: Bogdan Knezevic - Co-founder & CEO at Kaleidoscope.bio
21:16
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Embark on a journey through the intricate world of biotech with Bogdan Kezevic, co-founder and CEO of Kaleidoscope Bio, and uncover the revolutionary software shaping the future of scientific research. Bogdan's leap from scientist to entrepreneur has led to groundbreaking solutions for the challenges plaguing biotech. In our chat, he shares how dat…
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Episode 50: Steven Reed - Co-Founder & CEO at HDT Bio
12:19
12:19
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What does it take to revolutionize the world of vaccines and touch lives across the globe? Join us on a riveting journey with Steven Reed, CEO and co-founder of HDT-Bio, as we explore the creation of the first refined tuberculosis vaccine and dive into the remarkable strides in RNA technology. This episode lifts the veil on the science that could r…
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Episode 49: Jeffrey Bacha - Chairman, Rakovina Therapeutics
21:45
21:45
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Join Jeffrey Bacha, a pioneer in the fight against cancer and the creative force behind Rakovina Therapeutics. For 25 years, Jeffrey has been reshaping the industry landscape, and today, he gives us a peek into his world of innovation. We venture into Rakovina's research and development of oncology drugs. exploring their groundbreaking technique co…
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Redefining the Canadian housing paradigm - Part II
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The intersection of climate change and housing crisis in Canada forms a pressing challenge, as extreme weather events become more frequent. Recent wildfires and events like the Saint-John River flood not only jeopardize housing structures but also contribute to displacement and homelessness. For this Big Thinking Podcast episode, Gabriel Miller is …
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Episode 48: Jonathan Thon - Founder & CEO at STRM.BIO
21:52
21:52
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Embark on a fascinating exploration of biotech entrepreneurship, guided by an expert who's been in the trenches: Jonathan Thon, CEO and founder of STRM.BIO. We'll give you an insider's view of his journey from academia to the cutting edge of biotech, unveiling his trailblazing work on platelet production and the transformative potential of extracel…
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Redefining the Canadian housing paradigm - Part I
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32:53
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The Canadian housing crisis is more than a financial challenge; it's a societal concern with deep-seated roots. The crisis has far-reaching consequences: escalating homes prices, limited affordable housing, and the impact of the pandemic have intensified the struggle and exacerbated social inequalities. For this Big Thinking Podcast episode, Gabrie…
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Episode 47: Oscar Segurado- CMO at ASC Therapeutics
22:00
22:00
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Ever wondered how far we've truly come in the realm of gene and cell therapies, and where we're headed next? This captivating conversation with Oscar Segurado, the CMO of ASC Therapeutics, will satisfy your curiosity. Oscar, a veteran in the biopharmaceutical industry, shares fascinating insights on ASC Therapeutics' groundbreaking innovation in pe…
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Droit de l'intelligence artificielle : l'importance d'une régulation juste
27:24
27:24
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Est-ce que ChatGPT, DALL-E et Midjourney vous dit quelque chose? Ces plates-formes sont quelques exemples parmi de nombreux nouveaux logiciels d'intelligence artificielle qui voient le jour actuellement. Durant ces dernières années, l'IA a été au centre de nombreux débats et discussions, notamment dans le monde académique. Alors que l'IA commence à…
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Episodes 46: Spiro Rombotis- CEO at Cyclacel
21:28
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We’re thrilled to share our enlightening exchange with Spiro Rombotis, the seasoned CEO of Cyclacel. He peels back the curtain on the breakthrough discovery of B53, a commonly mutated gene in cancer patients, and the inspiring success of FADRA, their lead drug in clinical trials. Furthermore, Spiro delves into the highs and lows faced by Cyclacel, …
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She-cession: unveiling the pandemic's impact on women in the workforce
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Historically, most recessions have been described as being "he-cessions"; most jobs lost were male dominated industries, and the women led sectors shortly followed. When the Covid-19 pandemic started, women's employment was hit especially hard by the economic slow down that followed, causing some to call it a "she-cession." But what exactly does th…
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In 2015, the Truth and Reconciliation Commission released its First Report which documented the experiences of more than 6,000 witnesses who survived living in residential schools as students. Eight years later, it is important to assess what progress we've made and what work remains for us to do in our journey towards Reconciliation. For this Big …
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Episode 45: Frank Borriello- Founder and CEO at Alloplex Biotherapeutics
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17:56
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Ever wondered about the people who are leading the fight against cancer, developing groundbreaking treatments, and changing lives? Meet Frank Boriello, the mind behind SUPLEXA cell therapy, and the CEO and founder of Alloplex Biotherapeutics. In our conversation, Frank shares the personal backstory that sparked his quest to revolutionize cancer tre…
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Episode 44: Max Darnell- CEO & Co-Founder at Modulus Therapeutics
14:18
14:18
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Max Darnell, CEO and co-founder of Modulus Therapeutics, takes us through his thrilling journey from bioengineering and systems biology to launching a biotech startup. Max unveils how his team's curiosity and motivation, along with their high throughput discovery platform, are revolutionizing cell and cell therapy component designs. Hear how Modulu…
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Episode 43: Pepper Landson- Co-Founder & CEO of Praetego
19:03
19:03
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Join 30-year industry veteran Pepper Landson, Co-founder and CEO of Praetego as she shares her inspiring journey that led her to tackle Alzheimer's and dementia through the innovative use of amadorins. Pepper's intriguing narrative not only highlights her commitment to the public health crisis surrounding these neurodegenerative diseases, but also …
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Episode 42: Dr. Timothy Miller - Co-Founder, President, & CEO at Forge Biologics
12:34
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Ever wonder how the complexities of gene therapies are addressed from bench to bedside? The creative solutions lie within the innovative approaches of seasoned professionals like Dr. Timothy Miller, Co-Founder, President, & CEO at Forge Biologics. With a fascinating career that interlaces academia, biotech, and entrepreneurship, Dr. Miller brings a…
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Episode 41: David Esposito - President and CEO at ONL Therapeutics
19:35
19:35
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What if your vision could be saved by the precise application of innovative biotech? Join us as we talk to David Esposito, President & CEO of ONL Therapeutics, and delve deep into his take on leadership. He shares how his military background has been instrumental in the successful management of clinical trials, particularly when navigating the unpr…
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Episode 40: Alfredo Andere - Co-Founder & CEO at LatchBio
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24:41
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Does the convergence of tech and biology hold the key to reshaping biotech's data infrastructure? Our recent chat with Alfredo Andere, Co-Founder and CEO at LatchBio, certainly supports this notion. This episode offers a deep dive into Alfredo's journey from being part of the Google Brain team to co-founding Latch Bio - a company that is making wav…
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Episode 39: Lucas Siow - CEO & Co-Founder at ProteinQure
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Embark on a journey into the forefront of biotech with Lucas Siow, the visionary behind ProteinQure, as he unveils the impact of his computational platform on peptide therapeutics and delves into the art of team building. Explore the fusion of medicinal chemistry and high throughput screens, discover the essence of benchmarking in drug discovery, a…
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Episode 38: Stephen Doyle - Chief Business Officer at ASLAN Pharmaceuticals
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For episode 38, we sit down with Stephen Doyle, Chief Business Officer at ASLAN Pharmaceuticals. Find out more about the challenges involved in developing innovative treatments and how ASLAN is addressing those difficulties as they work to bring new therapies like their novel atopic dermatitis treatment to the market. First In Human is a biotech-fo…
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Episode 37: David Bearss, Ph.D. - President and CEO of Halia Therapeutics
20:23
20:23
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For episode 37, we connect with David Bearss, President and CEO of Halia Therapeutics. Learn more about the connection between chronic inflammation and disease, and how Halia is using their novel therapies to treat both inflammatory disorders and neurological diseases. First In Human is a biotech-focused podcast that interviews industry leaders and…
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Episode 36: Romain Micol - CEO & Co-Founder at Combined Therapeutics
11:29
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For Episode 36, we chat with Romain Micol, CEO & Co-Founder of Combined Therapeutics. Stay tuned to learn how Combined Therapeutics is developing unique mRNA-based treatments to better protect the world from infectious disease and cancer. First In Human is a biotech-focused podcast that interviews industry leaders and investors to learn about their…
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Episode 35: Simon Allen - CEO at Anebulo Pharmaceuticals
13:14
13:14
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For Episode 35, we sit down with Simon Allen, CEO of Anebulo Pharmaceuticals. Find out how Anebulo is addressing the unmet need for treatment of acute cannabinoid intoxication and other substance use disorders with their innovative novel therapeutics. First In Human is a biotech-focused podcast that interviews industry leaders and investors to lear…
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Episode 34: Bruno Gagnon - SVP, Global Clinical Operations at Opthea
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For episode 34, we sit down with Bruno Gagnon [gag-nan], SVP of Global Clinical Operations at Opthea. Learn about how Opthea is working to better the quality of life for those suffering impaired vison by improving visual acuity with their novel therapeutic agent. First In Human is a biotech-focused podcast that interviews industry leaders and inves…
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Episode 33: Aaron Morris - CEO & Co-Founder at PostEra
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For episode 33, we connect with Aaron Morris Co-Founder & CEO at PostEra. Find out what the difficult process of drug discovery may look like in the future, and how PostEra is looking to drastically speed it up through the application of AI. First In Human is a biotech-focused podcast that interviews industry leaders and investors to learn about th…
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Episode 32: Nicolas Tilmans - Founder & CEO at Anagenex
22:46
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For episode 32, we chat with Nicolas Tilmans, Founder & CEO at Anagenex. Stay tuned to learn how Anagenex is combining the power of machine learning and biochemistry to revolutionize the drug discovery process. First In Human is a biotech-focused podcast that interviews industry leaders and investors to learn about their journey to in-human clinica…
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Episode 31: Ganesh Padmanabhan - CEO at Autonomize AI
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For episode 31, we sit down with Ganesh Padmanabhan, CEO at Autonomize AI. Find out how Autonomize AI is working to better contextualize healthcare data by applying human-centric artificial intelligence to the problem. First In Human is a biotech-focused podcast that interviews industry leaders and investors to learn about their journey to in-human…
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L'avortement au Canada est-il un droit acquis?
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Bienvenue sur la page de notre balado Voir Grand, où l'on discute de quelques unes des questions les plus importantes de notre époque avec des chercheur.se.s de premier plan. Suite au renversement de l'arrêt Roe contre Wade par la Cour suprême des États-Unis l'an dernier et aux récentes interdictions de procédures d'avortement au sud de la frontièr…
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Episode 30: Craig Lipset - Co-Chair at DTRA
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For episode 30, we sit down with Craig Lipset, co-chair at the Decentralized Trials & Research Alliance. Learn more about the future of decentralized trials and how the increasing prevalence of remote and hybrid research can lead to more accessible and equitable trial participation. First In Human is a biotech-focused podcast that interviews indust…
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Welcome to the Big Thinking Podcast, where we talk to leading researchers about their work on some of the most important and interesting questions of our time. Gabriel Miller, President and CEO of the Federation, is our host. Artificial Intelligence is on the rise, and ChatGPT is one of the most prominent examples of a new technology that is changi…
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Episode 29: Aneesh Chopra - President at CareJourney
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For episode 29, we chat with Aneesh Chopra , President at CareJourney. Stay tuned to hear from the United States first Chief Technology Officer about how the private and public sectors can intersect in the pursuit of solving meaningful world problems. First In Human is a biotech-focused podcast that interviews industry leaders and investors to lear…
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Welcome to the Big Thinking Podcast, where we talk to leading researchers about their work on some of the most important and interesting questions of our time. Gabriel Miller, President and CEO of the Federation, is our host. Digital technologies are reshaping every aspect of our society, and books are no exception. But as physical objects, books h…
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Episode 28: Trevor Martin - Co-Founder & CEO, Mammoth Bioscience
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For episode 28 we connect with Trevor Martin, Co-Founder & CEO of Mammoth Bioscience. Learn how Mammoth is utilizing CRISPR technology to develop innovative genetic treatments, and what challenges a platform biotech company like themselves faces as they grow and work towards their goals. First In Human is a biotech-focused podcast that interviews i…
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From the Jheri curl to TikTok: Canada and the global business of Black beauty
28:27
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Welcome to the Big Thinking Podcast, where we talk to leading researchers about their work on some of the most important and interesting questions of our time. Gabriel Miller, President and CEO of the Federation, is our host. Every day we are bombarded by words and images telling us what we should find beautiful, and what we should aspire to look l…
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Episode 27: Sean P. Bohen - CEO at Olema Oncology
17:12
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For episode 27, we sit down with Sean Bohen, CEO of Olema Oncology. Stay tuned to learn what the future of personalized cancer treatment holds, and learn how Olema is helping to address the disparity in available care for women. First In Human is a biotech-focused podcast that interviews industry leaders and investors to learn about their journey t…
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Episode 26: Margo Georgiadis - CEO & Co-Founder of Montai Health
19:57
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For episode 26, we chat with Margo Georgiadis, CEO & Co-Founder of Montai Health. Find out about Montai’s creative approach to tackling chronic disease by harnessing the power of nature to find safer, more effective treatment options. First In Human is a biotech-focused podcast that interviews industry leaders and investors to learn about their jou…
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Is sport a means for Indigenous self-determination in Canada?
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Welcome to the Big Thinking Podcast, where we talk to leading researchers about their work on some of the most important and interesting questions of our time. Gabriel Miller, President and CEO of the Federation, is our host. Sports aren’t just fun and games, they’re a deeper part of who we are and where we come from. Today’s conversation is about …
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