Dr. Jeff Williams' Discussion forum for biotechnology, pacemakers, defibrillators, and electrophysiology studies including ablation.
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Each week, renowned editor-in-chief of the Journal of the American College of Cardiology (JACC), Valentin Fuster, MD, PhD, MACC, records free podcasts highlighting journal findings. To keep clinicians updated on the most important science emerging in clinical and translational cardiology, Dr. Fuster provides an overview of the weekly edition, as well as a short summary of each manuscript. Encompassing JACC and nine cardiovascular specialty journals, the JACC family of journals rank among the ...
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Deep Learning-Based Electrocardiogram Analysis Predicts Biventricular Dysfunction and Dilation in Congenital Heart Disease
11:27
11:27
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Dr. Valentin Fuster evaluates a deep learning model designed to predict left and right ventricular dysfunction and dilation in congenital heart disease patients using ECG and CMR data. The research demonstrated that AI ECG can reliably identify significant cardiovascular issues, though future work should focus on refining thresholds and validating …
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Treatment of Transcatheter Aortic Valve Thrombosis: JACC Review Topic of the Week
9:07
9:07
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Dr. Valentin Fuster discusses the treatment and diagnosis of transcatheter aortic valve thrombosis, focusing on its manifestations, diagnostic techniques using multi-slice computed tomography, and a proposed treatment algorithm. It highlights the difference between subclinical and clinical thrombosis and provides a detailed approach to managing bot…
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Low-Dose Rivaroxaban Plus Aspirin in Fragile Patients After Lower Extremity Revascularization
9:13
9:13
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Dr. Valentin Fuster discusses a study on the effects of low-dose rivaroxaban combined with aspirin in fragile patients after lower extremity revascularization, focusing on the balance between efficacy and safety. It highlights that while frailty increases the risk of adverse outcomes, rivaroxaban reduces ischemic events but also raises bleeding ris…
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Efficacy of Semaglutide by Sex in Obesity-Related Heart Failure With Preserved Ejection Fraction: STEP-HFpEF Trials
10:16
10:16
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Dr. Valentin Fuster discusses a study on the efficacy of semaglutide for treating obesity-related heart failure with preserved ejection fraction, highlighting that the drug significantly reduced body weight and improved heart failure symptoms in both men and women. Notably, women experienced greater weight loss than men, but this did not translate …
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In this episode, Dr. Valentin Fuster covers four original papers focusing on cardiovascular disease. Highlights include the effectiveness of semaglutide in reducing weight and improving heart failure symptoms, long-lasting effects of OPASAN on lipoprotein(a) levels, the impact of low-dose rivaroxaban plus aspirin on fragile patients post-revascular…
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The Off-Treatment Effects of Olpasiran on Lipoprotein(a) Lowering: OCEAN(a)-DOSE Extension Period Results
11:12
11:12
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In this episode, Dr. Valentin Fuster explores findings from the Phase 2 OCEAN-LDO trial assessing the off-treatment effects of the RNA-based drug alpcisiran on lipoprotein(a) [Lp(a)] levels. The study found that high doses of alpcisiran reduced Lp(a) levels by up to 95% during treatment, with a sustained reduction of 27-76% persisting up to 96 week…
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Structural Cardiac Interventions in Patients with Heart Failure: JACC Scientific Statement
40:38
40:38
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In this episode, Dr. Valentin Fuster provides an overview of a scientific statement on structural cardiac interventions in heart failure. It details advances in percutaneous therapies for ventricular reshaping, valvular heart disease interventions, and tricuspid valve issues, while also highlighting gaps in current treatments and areas for future r…
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Clinical and Analytical Performance of a Novel Point-of-Care High-Sensitivity Cardiac Troponin I Assay
12:26
12:26
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Audio Commentary by Dr. Valentin Fuster, Emeritus Editor in Chief
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Prescription Patterns for Sodium Glucose Cotransporter-2 Inhibitors in US Health Systems
9:04
9:04
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Audio Commentary by Dr. Valentin Fuster, Emeritus Editor in Chief
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Kidney and Cardiovascular Effectiveness of SGLT2 Inhibitors Versus GLP-1 Receptor Agonists in Type 2 Diabetes
9:42
9:42
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Audio Commentary by Dr. Valentin Fuster, Emeritus Editor in Chief
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Optimizing Management of Stable Angina: A Patient-Centered Approach Integrating Revascularization, Medical Therapy, and Lifestyle Interventions
37:17
37:17
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Audio Commentary by Dr. Valentin Fuster, Emeritus Editor in Chief
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Clinical Significance of Diffusion-Weighted Brain MRI Lesions After TAVR: Results of a Patient-Level Pooled Analysis
10:56
10:56
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Audio Commentary by Dr. Valentin Fuster, Emeritus Editor in Chief
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Audio Summary of the August 20 issue of JACC, by Dr. Valentin Fuster, Emeritus Editor in Chief
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Myocardial Strain Measured by Magnetic Resonance Imaging Predicts Cardiovascular Morbidity and Death
10:56
10:56
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Audio Commentary by Dr. Valentin Fuster, Emeritus Editor in Chief
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Comparison of Pressure vs Volume Overload Ventricular Wall Stress in Patients with Valvular Heart Disease
11:10
11:10
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Audio Commentary by Dr. Valentin Fuster, Emeritus Editor in Chief
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Contemporary Pediatric Heart Transplant Waitlist Mortality
8:41
8:41
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Audio Commentary by Dr. Valentin Fuster, Emeritus Editor in Chief
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Real-world 1-Year Results of Tricuspid Edge-to-Edge Repair from the bRIGHT Study
10:16
10:16
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Audio Commentary by Dr. Valentin Fuster, Emeritus Editor in Chief
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Ending trans fat-the first-ever global elimination program for a noncommunicable disease risk factor: JACC International
12:28
12:28
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Audio Commentary by Dr. Valentin Fuster, Emeritus Editor in Chief
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Audio Summary of the August 13 issue of JACC, by Dr. Valentin Fuster, Emeritus Editor in Chief
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Audio Summary of the August 6 issue of JACC, by Dr. Valentin Fuster, Emeritus Editor in Chief
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A Patch Wearable Cardioverter Defibrillator for Patients at Risk of Sudden Cardiac Arrest
10:03
10:03
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Audio Commentary by Dr. Valentin Fuster, Emeritus Editor in Chief
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Pericardial Diseases and Best Practices for Pericardiectomy: JACC State-of-the-Art Review
42:56
42:56
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Audio Commentary by Dr. Valentin Fuster, Emeritus Editor in Chief
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The influence of epicardial resistance on microvascular resistance reserve
8:46
8:46
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Audio Commentary by Dr. Valentin Fuster, Emeritus Editor in Chief
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Effect of Time-Varying Exposure to School-Based Health Promotion on Adiposity in Childhood
12:04
12:04
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Audio Commentary by Dr. Valentin Fuster, Emeritus Editor in Chief
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Liraglutide Improves Myocardial Perfusion and Energetics and Exercise Tolerance in Patients with Type 2 Diabetes
9:58
9:58
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Audio Commentary by Dr. Valentin Fuster, Emeritus Editor in Chief
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