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Weekly updates on new data and best practices in patient care for a variety of infectious diseases including COVID-19, HIV, and viral hepatitis, from Clinical Care Options. Gain practical strategies and earn CME/CE credit for selected episodes.
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The Dispensary

Lisa Binkley, Tina Ross

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This podcast will address the public health strategy of Harm Reduction, which is designed to reduce the adverse consequences of drug and alcohol use. The Dispensary will address cutting-edge approaches to substance abuse problems, information on Syringe Exchange Programs (SSPs), HIV/HCV education, and harm reduction methods to prevent overdoses and save lives. Harm Reduction experts and peer guests will educate the public about drugs while dispelling popular myths, misinformation, and stigma.
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The Hep-cast

World Hepatitis Alliance and Gilead Sciences Europe Limited

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Join us as we go beyond the statistics to explore the human impact of one of the greatest health crises of our time. Over 350 million people are living with viral hepatitis worldwide. The Hep-cast is about the people whose lives have been changed by viral hepatitis and those fighting to eliminate it as a public health threat by 2030. Guests include people living with viral hepatitis, healthcare professionals, policymakers, and activists. They will expose the human cost of this cruel virus an ...
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Vision To Prevent and Cure Liver Disease Mission To advance and disseminate the science and practice of hepatology, and to promote liver health and quality patient care AASLD is the leading organization of scientists and healthcare professionals committed to preventing and curing liver disease. AASLD was founded in 1950 by a small group of leading liver specialists (including Hans Popper, Leon Schiff, Fred Hoffbauer, Cecil Watson, Jesse Bollman, and Sheila Sherlock, to name a few) to bring t ...
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show series
 
In this episode, Stuart C. Gordon, MD, FACP, FACG, AGAF, FAASLD; Marlyn J. Mayo, MD; and Brenda Remo discuss strategies for optimizing PBC pruritus care in the clinic setting. Listen to their conversation on how important it is to ask patients about their pruritus, validate their symptoms and feelings, and offer treatment options framed with realis…
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In this episode, Stuart C. Gordon, MD, FACP, FACG, AGAF, FAASLD; Marlyn J. Mayo, MD; and Brenda Remo discuss the patient experience with cholestatic pruritus in PBC. Listen to their conversation on how people describe the experience of cholestatic pruritus, the extent to which pruritus negatively affects quality of life, and the importance of educa…
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In this episode, Bradley N. Gaynes, MD, MPH, and Glenn J. Treisman, MD, PhD, discuss the importance of screening, diagnosing, and treating depression in people living with HIV. They illustrate their discussion through a patient case and provide strategies for accomplishing this, including creation of a virtual network and employment of measurement-…
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In this episode, Cristina Mussini, MD,and William R. Short, MD, MPH, FIDSA,discuss the potential role of ART in weight change among people living with HIV. Listen to their conversation on whether ART switch can lead to weight loss after weight gain and how to counsel people living with HIV on weight loss options, including lifestyle modifications a…
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In this episode, Linda-Gail Bekker, MBChB, DTM&H, DCH, FCP(SA), PhD, uses a case study to illustrate why patients living with HIV may disengage with their care and how best to reengage them once they present at the clinic, including discussion of: The valid reasons patients have for disengaging with their HIV care Why the return to care should be c…
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In this second podcast of our series, hear expert faculty explore the CDC recommendations for mpox protection and discuss how vaccination can lead to immunologic equity. Topics include: Should we consider mpox an STI? What strategies can be used to improve mpox vaccination and overcome the challenges of vaccine implementation? Can mpox vaccine be c…
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Hear expert faculty answer common questions about the risk, impact, and recommendations for protection against mpox, including: Why is mpox relevant to clinical practice? Who is at highest risk for mpox? How is mpox transmitted, and what are the clinical manifestations and complications of mpox infections? What are current ACIP recommendations for …
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In this episode, Roger Bedimo, MD, MS, FACP, examines patient and regimen-based PrEP barriers and discusses practical interventions to support PrEP adherence in key populations. Topics covered include: Individual and community perspectives on PrEP barriers Key barriers by principal populations Strategies to support PrEP delivery PrEP options for ke…
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In this episode, Roger Bedimo, MD, MS, FACP, discusses strategies to overcome health disparities to improve PrEP uptake, including: Targeting key populations that would benefit from PrEP but have low rates of uptake, such as transgender women and people who inject drugs Addressing intersectionality Overcoming implicit bias Addressing PrEP inequity …
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In this episode, Roger Bedimo, MD, MS, FACP, examines provider-based and structural PrEP barriers and discusses practical methods for healthcare professionals to overcome these challenges. Topics covered include: Potential provider barriers to prescribing PrEP Strategies to facilitate conversations about PrEP Addressing the gap in PrEP provider tra…
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In this episode, Tristan J. Barber, MA, MD, FRCP, and Roger Bedimo, MD, MS, FACP, help you decide whether and how to modify ART in virologically suppressed individuals by critically appraising whether using newer agents may improve their treatment satisfaction. Listen to their conversation about their own approaches to evaluating whether each perso…
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In this episode, Jonathan Appelbaum, MD, FACP, AAHIVS, discusses the updated CDC guidance on how to monitor for HIV in people receiving PrEP, including: Rationale for why HIV monitoring differs for people receiving LA vs daily PrEP Description of LEVI syndrome How to transition a person from LA PrEP to HIV ART if they test positive for HIV Presente…
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In this episode, Jonathan Appelbaum, MD, FACP, AAHIVS, discusses the newest data supporting LA ART use in people with adherence challenges or viremia, including: The LATITUDE study, an open-label phase III study of LA CAB + RPV in people with a suboptimal response or nonadherence to oral ART Updates to the Ward 86 cohort, which showed 81% of patien…
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In this episode, Angela Branche, MD, FIDSA, and Jewel Mullen, MD, MPH, MPA, FACP, address commonly asked questions about the RSV vaccine, including: Considerations for vaccine eligibility Recommendations for pregnant persons Vaccine administration based on RSV seasonality Use of the vaccine in persons receiving immunosuppressive medications Safety …
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In this episode, Jewel Mullen, MD, MPH, MPA, FACP, discusses strategies for implementing RSV vaccines into practice, with an emphasis on: Understanding the reasoning for Advisory Committee on Immunization Practices RSV vaccine recommendations Factors that influence vaccine uptake and patient decision-making Considerations for patient and healthcare…
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In this episode, Angela Branche, MD, FIDSA, explores the burden of RSV disease in older adults, including: RSV seasonality and disease burden Symptoms and complications of RSV infection Older age as a key risk factor for severe RSV disease and complications (eg, pneumonia, hospitalization) Comorbidities associated with increased risk of RSV hospita…
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Using common case scenarios, Robert H. Hopkins, Jr., MD, MACP, and Laura P. Hurley, MD, MPH, discuss strategies for optimizing shingles vaccine uptake, including: The pathophysiology of shingles to better understand risk and burden CDC guidelines and ACIP shingles vaccine recommendations, including considerations for those who are immunocompromised…
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In this episode, Samantha Strong, PharmD, BCACP, AAHIVP, CDCES, and Nimish Patel, PharmD, PhD, AAHIVP, cover the most impactful clinical studies presented at CROI 2024, including: New data on long-acting ART, including: The CARES study of LA CAB + RPV in a sub-Saharan African population using a public health approach The IMPAACT 2017 MOCHA study ev…
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In this episode, learn how early and sustained HBV care can be enhanced by expanding the role of primary care providers in HBV management. Learn how to: Engage key stakeholders in the provision of HBV care​ Provide HBV management resources to support PCPs who are doing screening​ Consider specialty and primary care collaborations that empower PCPs …
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In this episode, Gregory Huhn, MD, MPHTM, uses a case study to explore the reasons healthcare professionals and people living with HIV may want to further optimize ART in the setting of viral suppression. To determine the best outcome for this case study, Dr Huhn discusses the reasons individuals may not be satisfied with daily oral ART and examine…
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In this episode, Maria Buti, MD, and her patient discuss opportunities to optimize care for people living with hepatitis B virus (HBV), including: Barriers to HBV screening, including patient- and provider-specific barriers (eg, lack of education, failure to disclose or discuss risk factors, perceived low risk, stigma) Applying CDC recommendations …
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In this episode, Joseph J. Eron, Jr., MD, and Monica Gandhi, MD, MPH, discuss the key HIV studies from CROI 2024 that are influencing their clinical practice, including: New data surrounding long-acting ART, including: The CARES study of LA CAB + RPV in a Sub-Saharan African population using a public health approach The IMPAACT 2017 MOCHA study eva…
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In this episode, Mark S. Sulkowski, MD, FIDSA, FAASLD; Tatyana Kushner, MD, MSCE; Paul Y. Kwo, MD; and patient advocate Jacki Chen, PhD, consider barriers and solutions for more expansive HBV treatment in the United States. Topics include: Patient subgroups to consider for treatment outside guideline criteria Adverse event and cost-effectiveness co…
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In this episode, Robert Wong, MD, MS, and a patient discuss opportunities to optimize care for people living with hepatitis B virus (HBV), including: Opportunities to improve patient education, including education for expectant mothers with HBV Potential cultural considerations that may result in delayed HBV diagnosis and care Stigma reduction with…
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Listen to Roger Bedimo, MD, MS, FACP, discuss considerations for older people living with HIV, including: Polypharmacy and deprescribing The risk of cardiovascular events with various ART regimens Approaches for managing weight gain Presenter: Roger Bedimo, MD, MS, FACP Professor of Medicine Interim Director, Office of Global Health UT Southwestern…
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In this episode, Dr. Bedimo discusses best practices for individualized care in transgender women living with HIV, including: Providing services in a gender-affirmative care model Proactive counseling on drug-drug interactions with gender-affirming hormone therapy Strategies to reduce adverse events Presenter: Roger Bedimo, MD, MS, FACP Professor o…
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In this episode, Renslow Sherer, MD, and Trinh P. Vu, PharmD, BCIDP, discuss how to optimize the use of COVID-19 antivirals and how to navigate drug-drug interactions between COVID-19 treatments and a patient’s home medications. Their discussion includes: Current COVID-19 landscape COVID-19 testing and vaccination recommendations Treatment guidelin…
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In this episode, Nancy Reau, MD, discusses new data on hepatitis B virus presented at AASLD 2023, including: Current therapies Studies 108 and 110: Factors Linked With Lack of Virologic Suppression After 8 Yr of TAF or TDF Kaiser Permanente Northern California: HCC or Death With TDF vs ETV for Chronic Hepatitis B Early vs Late Postpartum Cessation …
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In this episode, LaRon E. Nelson, PhD, RN, FNP, FNAP, FNYAM, FAAN, discusses the role that healthcare professionals (HCPs) may be playing in their patients’ pre-exposure prophylaxis (PrEP) persistence and strategies to modify their approach to encourage persistence, from Clinical Care Options (CCO), including: Racial disparities in the PrEP care co…
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In this episode, Nancy Reau, MD, and her patient discuss opportunities to optimize care for people living with hepatitis B virus and hepatitis delta virus, including: The importance of patient education along the care continuum Ensuring smooth transitions of care and communication between medical teams Screening hepatitis delta in persons with chro…
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In this episode, David Saunders discusses the value of nonstigmatizing discussions between people using HIV pre-exposure prophylaxis (PrEP) and healthcare professionals, including: Encouraging accountability to individualize adherence strategies and improve persistence to PrEP Reducing stigma, discrimination, and prejudice in healthcare settings to…
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In this episode, Sarah M. Wood, MD, MS, discusses data and recommendations for long-acting pre-exposure prophylaxis (PrEP) as a strategy to support PrEP persistence and engagement for adolescents, including: The PrEP care continuum for adolescents System barriers to PrEP coverage and privacy concerns for adolescents The benefits and challenges of s…
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In this episode, Angela Branche, MD, discusses RSV vaccines in older adults, including: Current Advisory Committee on Immunization Practices recommendations Risk factors associated with severe RSV disease, including RSV-related hospitalizations Approach to stratifying risk factors (eg, age, comorbidities) in determining which adults may benefit fro…
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In this episode, Douglas Dieterich, MD, leads a panel discussion with Camilla S. Graham, MD, MPH, and Robert Wong, MD, MS, to consider advantages and barriers to universal screening for chronic HBV infection and universal HDV screening in adults with HBV in the United States. Topics include: Updated CDC recommendations for one-time universal screen…
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In this episode, Tavell L. Kindall, PhD, DNP, ARNP, FNP-BC, AACRN, AAHIVS, FAANP, and Anne Teitelman, PhD, FNP-BC, FANNP, FAAN, discuss key PrEP considerations for advanced practice providers in primary care settings, including: The importance of having PrEP navigators to help with logistics and be a point of contact for patients Where to find educ…
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In this podcast episode, Mark Brennan-Ing, PhD, and Nina I. Martinez discuss mental health challenges in people living with HIV and much-needed strategies to overcome these challenges to optimize engagement in HIV care, including: The increased rates of mental health disorders and substance use among people living with HIV How mental health disorde…
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In this podcast episode, Isolde Butler, MD, MPH, a healthcare professional caring for people living with HIV, and Marissa Gonzalez, an individual living with HIV, discuss strategies to improve healthcare professionals’ competencies in delivering optimal HIV care from the start to better support patients in overcoming barriers to sustained care enga…
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In this podcast episode, Babafemi Taiwo, MBBS, and Vincent Crisostomo discuss the evolving treatment landscape for aging people living with HIV, encompassing the clinical and external resources necessary to support physical and psychosocial health. The topics discussed include: • Mindful prescribing and understanding the impact an HIV diagnosis can…
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In this episode, Kevin Astle, PharmD, BCPS, BCACP, AAHIVP, CDCES, discusses data and recommendations for providing HIV prevention options as a strategy to support PrEP persistence and engagement, including: Postexposure prophylaxis (PEP) recommendations and the data for PEP-in-Pocket Offering PrEP to everyone who receives PEP Currently recommended …
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During the 2023 American Association for the Study of Liver Diseases conference, exciting and important results from many primary biliary cholangitis (PBC) clinical trials were reported, including 3 late-breaking studies on the PPAR-δ agonist seladelpar, the dual PPAR agonist elafibranor, and the combination of the FXR agonist obeticholic acid and …
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In this episode, Dr Tavell Kindall and Jona Tanguay discuss actionable strategies for advanced practice providers to increase the frequency at which PrEP is offered and initiated in primary care settings. Topics covered include: Available training resources on how to offer PrEP in primary care Affordable, accessible PrEP options, including patient …
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In this third of 3 episodes, global HIV experts and advocates discuss the current status of HIV cure research, including key concepts to understand and communicate when counselling patients, colleagues, and the broader community on HIV cure: Latest understanding of the viral reservoir New insights and questions on the best timing for cure intervent…
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In this podcast, Julie Ann Justo, PharmD, MS, FIDSA, BCPS, discusses treatment of carbapenem-resistant Enterobacterales (CRE) infections, including: Burden of CRE infections in the United States Mechanisms of resistance Changing epidemiology Use of rapid diagnostic tests IDSA guidance recommendations, including supporting data Approach to designing…
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During the 2023 American Association of the Study of Liver Diseases (AASLD) conference, exciting and important results from many primary biliary cholangitis (PBC) clinical trials were reported, including 3 late-breaking studies on the PPAR-delta agonist seladelpar, the dual PPAR agonist elafibranor, and the combination of the FXR agonist obeticholi…
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In this episode, Errol L. Fields, MD, PhD, MPH, and Armonté Butler, MPH, a pre-exposure prophylaxis (PrEP) advocate, discuss strategies for overcoming barriers to uptake of PrEP for HIV in adolescents and young adults, based on the unique needs of this patient population. Topics covered include: Methods for building trust between patients and provi…
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During the 2023 American Association of the Study of Liver Diseases (AASLD) conference, exciting and important results from many primary biliary cholangitis (PBC) clinical trials were reported, including 3 late-breaking studies on the PPAR-delta agonist seladelpar, the dual PPAR agonist elafibranor, and the combination of the FXR agonist obeticholi…
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In this episode, Martin Rios discusses how pre-exposure prophylaxis (PrEP) persistence depends on healthcare professional knowledge, including: Their own experiences with the various PrEP providers they have seen The relief that has come with seeing PrEP providers who are supportive and knowledgeable about the different PrEP options The challenges …
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In this episode, Meredith Clement, MD, and Whitney C. Irie, MSW, PhD, discuss key considerations for pre-exposure prophylaxis (PrEP) uptake in cisgender women, including: How to incorporate conversations on PrEP during a short clinic visit Helpful resources about PrEP to share with patients Leveraging clinic staff to improve PrEP uptake and persist…
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In this episode, Helen Y. Chu, MD, MPH, shares updates on RSV seasonality, including: Surveillance limitations due to the testing availability in adults Current 2023/2024 season trends, including predictions for other respiratory viruses (eg, influenza, SARS-CoV-2) Considerations for RSV administration RSV vaccine coadministration with influenza an…
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In this episode, Rick Zimmerman, MD, MPH, FAAFP, discusses RSV vaccines in older adults, including: Breakthroughs in RSV vaccine development RSV vaccine snapshot in older adults FDA-approved RSV vaccines for older adults CDC evidence to recommendations framework for vaccines RSV burden in older populations Benefits and harms of RSV vaccination RSV …
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