Best IMD Podcasts (2024)

1
Shortcast: Pediatric palliative care for IMD: 20-year survey of outpatients at a Brazilian hospital 4:30

1h ago4:30

4:30

Dr Gustavo Spolador discusses the paucity of data around palliative care in Inherited Metabolic Disease and some of his own observations in a Brazilian quaternary hospital.Pediatric palliative care for metabolic diseases: 20-year epidemiological survey of outpatients at a Brazilian quaternary hospitalGustavo Marquezani Spolador, et alhttps://doi.or…

1
Why does artificial intelligence need regulating? 19:50

18h ago19:50

19:50

Mike and Amit discuss the ins and outs of upcoming regulations in AI. ********* Michael Wade is a Professor of Innovation and Strategy and Director of the IMD Global Center for Digital Business Transformation. He also holds the Cisco Chair in Digital Business Transformation. An expert in digital transformation, he has published 10 books and more th…

1
S8 Episode 3 - In Vienna with Ian Palmer of Inchdairnie Distillery and Roland Grain of Ardgowan Distillery with whisky chat from the 2 Gordons 52:54

9d ago52:54

52:54

The 2 Gordons welcome Ian Palmer of Inchdairnie, referenced in the last podcast. Ian talks about the wording on Scotch whisky labels and talks about his own journey in establishing this wonderful Fife distillery. Roland Grain is the man behind Ardgowan distillery in Inverkip who also hosted the Potstill Masterclass Festival in Vienna where Gordon D…

1
Pregnancy in Urea Cycle Disorders 17:08

7d ago17:08

17:08

This episode brings together two popular podcast topics, pregnancy and urea cycle disorders. Dr Margreet Wagenmakers and Dr Karolina Stepien share recent insights from a literature review and international survey exploring the experiences of mothers with urea cycle disorders. The management and clinical outcomes of pregnancies in women with urea cy…

1
Pt.2 Chris Douvos of Ahoy Capital on the evolution of the emerging managers segment 18:23

9d ago18:23

18:23

Part 2 of our conversation with Chris Douvos, on how the Emerging Managers segment in Venture Capital has evolved since 2010. Chris Douvos founded Ahoy Capital in 2018, focusing on backing emerging venture capital fund managers. With nearly two decades in venture capital, he's a pioneer in the micro-VC movement. At Ahoy Capital, the focus is on int…

1
Shortcast: Clinical experience with glycerol phenylbutyrate in 20 patients with UCDs 9:15

14d ago9:15

9:15

Mel McSweeney and Dr Mildrid Yeo briefly outline the approach to urea cycle disorder management and the Gt Ormond Street experience using glycerol phenylbutyrate as a nitrogen scavenger. Clinical experience with glycerol phenylbutyrate in 20 patients with urea cycle disorders at a UK paediatric centreMildrid Yeo, et alhttps://doi.org/10.1002/jmd2.1…

1
How AI is taking the Biotech industry by storm 16:09

21d ago16:09

16:09

Mike & Amit talk about the future of Biotech, and how Artificial Intelligence may speed up healthcare and drug development. ********* Michael Wade is a Professor of Innovation and Strategy and Director of the IMD Global Center for Digital Business Transformation. He also holds the Cisco Chair in Digital Business Transformation. An expert in digital…

1
Liver directed gene therapy 33:50

22d ago33:50

33:50

The podcast returns to the subject of gene therapy, with Julien Baruteau, Nicola Brunetti-Pierri, and Paul Gissen discussing the potential of liver directed therapies with an emphasis on Wilson disease, Crigler-Najjar syndrome and PKU.Liver-directed gene therapy for inherited metabolic diseasesJulien Baruteau, Nicola Brunetti-Pierri, Paul Gissenhtt…

1
TV Narendran, CEO & Managing Director of Tata Steel 42:39

29d ago42:39

42:39

Anticipating rising raw material costs, Tata Steel’s CEO & Managing Director TV Narendran tells IMD President Jean-François Manzoni how he introduced a change management process to instill a culture of future readiness at the 100-year-old industrial company.By IMD

1
The Interview: Chris Tung, President of Strategic Development at Alibaba Group 34:24

25d ago34:24

34:24

Chris Tung is President of Strategic Development at Alibaba Group, a Chinese multinational specializing in e-commerce, retail, and technology. He tells IMD's Amit Joshi how the company is integrating AI to optimize... -- Read our magazine, I by IMD, here. Discover IMD's leadership programmes here.By IMD

1
Henrik Andersen, CEO of sustainable energy leader Vestas 54:16

25d ago54:16

54:16

Henrik Andersen discusses with IMD President Jean-François Manzoni the challenges of navigating supply chain disruptions and soaring raw material costs over the past three years, and why he changed the wind farm developer’s culture to encourage openness and trust.By IMD

1
The Interview: Morra Aarons-Mele 38:30

28d ago38:30

38:30

Morra Aarons-Mele, author and host of the Anxious Achiever podcast, discusses the strategies to help turn anxiety into a leadership superpower. -- Read our new magazine, I by IMD, here. Discover IMD's leadership programmes here.By IMD

1
Shortcast: Psychosocial issues and coping strategies in families affected by long-chain FAOD 6:41

28d ago6:41

6:41

Dr Maren Thiel, Chair of the German speaking self-help group for fatty oxidation disorders, presents work completed with the Freiburg metabolic team looking at psychosocial issues and coping strategies in families affected by LC-FAOD.Psychosocial issues and coping strategies in families affected by long-chain fatty acid oxidation disordersMaren Thi…

1
Chris Douvos of Ahoy Capital, discusses the evolution of the emerging managers segment Pt.1 14:46

1M ago14:46

14:46

In this new episode of Capital Conversations, we explore “How the Emerging Managers segment in Venture Capital has evolved since 2010” with Chris Douvos. Chris Douvos founded Ahoy Capital in 2018, focusing on backing emerging venture capital fund managers. With nearly two decades in venture capital, he's a pioneer in the micro-VC movement. At Ahoy …

1
Erik Fyrwald, CEO of leading agriculture firm Syngenta Group 47:27

1M ago47:27

47:27

Regenerative agriculture techniques are vital to improve the resilience of crops and help farmers achieve humanity’s dual objective of growing more food using less land, the CEO of the Swiss agriculture group tells IMD President Jean-François Manzoni, as he advocates for carbon labelling on produce.By IMD

1
Sora and Gemini: Innovations in AI 18:03

1M ago18:03

18:03

The 21st century has been dominated by video. At its start, camcorders allowed amateurs to make their own home movies, and by 2023, the likes of TikTok had become ubiquitous. Phones and social media platforms made shooting and editing child play. But 2024 is seeing another change, one that may shake the very foundation of video itself. Sora, from O…

1
Dilhan Pillay, CEO of Singapore’s global investment giant Temasek 53:14

1M ago53:14

53:14

Dilhan Pillay, CEO of Singapore’s global investment giant Temasek, discusses with Jean-François Manzoni the importance of a carbon tax and how his company is working to ensure ‘every generation prospers’ without sacrificing profits.By IMD

1
BH4 in tyrosine hydroxylase deficiency 16:25

1M ago16:25

16:25

Listener feedback link: https://form.jotform.com/240459204544050Kunwar Jung-KC and Alba Tristán-Noguero discuss tyrosine hydroxylase deficiency and explain how the tyrosine hyodroxylase cofactor, BH4, has shown early therapeutic potential in human neurons and a knock-in mouse model. Tetrahydrobiopterin (BH4) treatment stabilizes tyrosine hydroxylas…

1
S8 Episode 2 – Juliette Buchan of Glenallachie, Emma Anderson, Editor-in-Chief at Allt om Whisky + Whisky Labels and all the usual whisky chat and fun.! 1:05:03

1M ago1:05:03

1:05:03

This episode is released on International Women’s Day 2024 and the 2 Gordon’s celebrate with interviews with Juliette Buchan of Glenallachie and Emma Anderson, Editor-in-Chief at Allt om Whisky, Sweden’s premier whisky magazine. The Gordons look at whether it is within the rules to put a geographical region on a Scotch whisky label that is not one …

1
Shortcast: Lysinuric protein intolerance exhibiting RTA/Fanconi syndrome in a Japanese woman 4:02

1M ago4:02

4:02

Dr Hiroki Hanafusa presents the unusual case of a woman who was initially diagnosed with Fanconi Syndrome and later found to have Lysinuric Protein Intolerance.Lysinuric protein intolerance exhibiting renal tubular acidosis/Fanconi syndrome in a Japanese womanHiroaki Hanafusa, et alhttps://doi.org/10.1002/jmd2.12392…

1
How to proceed after a "negative" exome 23:07

2M ago23:07

23:07

A superlative trio, Dr Machteld Oud, Dr Clara van Karnebeek and Dr Saskia Wortmann join the podcast to explain the importance of diagnostics, why all exomes aren't equal and just how should you proceed after a 'negative' exome.How to proceed after “negative” exome: A review on genetic diagnostics, limitations, challenges, and emerging new multiomic…

1
Shortcast: Neuropsychological stability in classical galactosemia: A pilot study in 10 adults 3:13

2M ago3:13

3:13

Merel Hermans describes her work reviewing neuropsychological stability in adults with classical galactosemia.Neuropsychological stability in classical galactosemia: A pilot study in 10 adult patientsMerel E. Hermans, et alhttps://doi.org/10.1002/jmd2.12410By Journal of Inherited Metabolic Disease

1
Turning failure into success, with Zhike Lei 18:13

2M ago18:13

18:13

Zhike Lei is Professor of Leadership and Organizational Behavior at IMD. She is an award-winning organizational scholar and an expert on psychological safety, team dynamics, organizational learning, error management, and patient safety. Lei studies how organizations, teams, and employees adapt and learn in complex, time-pressured, consequence-laden…

1
Pt.2 Challenging Dogmatic Narratives in Venture Capital, with Fergal Mullen, Co-Founder & Partner at Highland Europe. 17:57

2M ago17:57

17:57

In the second part of Fergal Mullen's interview, the co-founder and Partner of Highland Europe provides a pragmatic take on venture capital practices, addressing key industry dogmas. Mullen questions the bias against first-time entrepreneurs and talks about the importance of getting feedback from founders. He delves into the significance of geograp…

1
Food or medicine? Nutritional therapies in IMD 16:58

2M ago16:58

16:58

Returning guests, Nina Stolwijk and Dr Carla Hollak, and their colleague Dr Annet Bosch, try to untangle the tricky subject of regulation in nutritional products used as therapies in IMD. They also present a framework for when a food should be considered a medicine. Food or medicine? A European regulatory perspective on nutritional therapy products…

1
Metabolic mysteries: Three children with neurological symptoms and coagulopathy 5:41

2M ago5:41

5:41

Shelby Mills on behalf of the UTH Medical Genetics Team, invites you to consider three mystery cases serving to hi-light some common, and some less common, presenting features for a treatable inherited metabolic disease.Arginase deficiency masked by cerebral palsy and coagulopathy—Three varied presentations of Latin American originShelby L. Mills, …

1
Adapting, Innovating and Learning from Failure, with Zhike Lei 21:44

2M ago21:44

21:44

When disaster strikes, or when goals are simply missed, blame often lands on the bosses. From CEOs to team leaders the buck has to stop somewhere, and when it does, action needs to be taken. But how should leaders approach failure? Zhike Lei says leaders in both civil society and corporations tend to try and tackle problems alone. But this is not t…

1
Movement disorders and mRNA therapy in Arginosuccinic aciduria 24:44

3M ago24:44

24:44

Dr Sonam Gurung and Dr Julien Baruteau discuss movement disorders in Arginosuccinic aciduria and explain how recent work with mRNA therapy shows potential as a treatment in this condition.The incidence of movement disorder increases with age and contrasts with subtle and limited neuroimaging abnormalities in argininosuccinic aciduriaGurung et alhtt…

1
Challenging Dogmatic Narratives in Venture Capital, with Fergal Mullen, Co-Founder & Partner at Highland Europe. 19:01

3M ago19:01

19:01

Fergal Mullen is a co-founder and Partner of Highland Europe focused on enterprise SaaS and consumer internet companies. He represents Highland Europe on the boards of GetYourGuide.com, AMCS, Nexthink, Bitmovin, Meditopia, Unibuddy, and Podimo. Highland Europe is currently investing from its 5th Fund which is just over €1B. In total, the firm manag…

1
Metabolic mysteries: Recurrent miscarriage and congenital anomalies 3:05

3M ago3:05

3:05

Dr Malak Alghamdi unravels the mystery of a 32-year-old woman with a history of recurrent miscarriage and early neonatal death with congenital anomalies. Classical phenylketonuria presenting as maternal PKU syndrome in the offspring of an intellectually normal womanMalak Ali Alghamdi, et al https://doi.org/10.1002/jmd2.12384…

1
How to manage emotions when facing defeat, with Zhike Lei 23:10

3M ago23:10

23:10

Experimentation can bring many benefits in the workplace. New products, cost-saving efficiencies, and profits are often the result of new and progressive ways of thinking. But having the confidence to try new methods comes with risks. Often we must fail on our way to success, and that failure can give rise to fear. Many fear admitting mistakes, say…

1
Hepatic presentations in mitochondrial depletion syndromes 10:52

3M ago10:52

10:52

In this podcast, Dr Roshni Vara discusses the experience of a single paediatric liver centre with children whose liver failure arose due to a mitochondrial DNA depletion syndrome.Hepatic presentations of mitochondrial DNA depletion syndrome in children: A single tertiary liver centre experienceR. Vara, et alhttps://doi.org/10.1002/jimd.12633…

1
S8 Ep1 – Not the Christmas Special ft Lochlea’s Patrick, Glenturret’s Jamie, Penderyn’s Richard, Berry Bros and Rudd’s Joe, Barra Distillery’s Debbie, Patrick Lutz and Susan Morrison of the SWE 44:32

3M ago44:32

44:32

The 2 Gordons start a New Year with a new series bringing interviews from a very snowy Baden in Switzerland which would have made a wonderful Christmas Special – all will be explained. Then it’s off to the capital of Scotland to visit Edinburgh’s newest whisky visitor attraction at the Scottish Whisky Experience and hear from the Chief Executive Su…

1
Shortcast: Lysosomal storage disorders identified in adult population from India 7:20

3M ago7:20

7:20

Professor Jayesh Sheth shares 20 years of insights on diagnosing adult onset lysosomal storage disorders at a tertiary genetic centre in India.Lysosomal storage disorders identified in adult population from India: Experience of a tertiary genetic centre and review of literatureJayesh Sheth, et alhttps://doi.org/10.1002/jmd2.12407…

1
Understanding failure, with Zhike Lei 17:49

3M ago17:49

17:49

World-beating organizations are always striving for success, but sometimes even the most dedicated teams fall short. Companies miss their sales goals, lose out on funding rounds, and have PR disasters. Failure, in short, is a natural part of life, and how firms cope with it is of vital importance. Zhike Lei says this may seem obvious, but in practi…

1
Genomic newborn screening: are we entering a new era of screening? 57:44

3M ago57:44

57:44

Dr David Bick, Dr Jim Bonham MBE and Henrietta Hopkins re-create a panel from the SSIEM Annual Meeting in 2022 to discuss the use of whole genome sequencing in NBS, asking "are we entering a new era of screening?"Genomic newborn screening: Are we entering a new era of screening?Ute Spiekerkoetter, et alhttps://doi.org/10.1002/jimd.12650…

1
Shortcast: A case of hyperlysinemia identified by urine newborn screening 4:57

4M ago4:57

4:57

Dr Sander Houten discusses a child with hyperlysinemia diagnosed via newborn screening and whether this reflects a disease or just a metabolic perturbation. This distinction is relevant as inducing this state may be a treatment option in GA1 or pyridoxine dependent epilepsy. A case of hyperlysinemia identified by urine newborn screeningMehdi Yegane…

1
JIMD Editor's Roundtable (2023) 39:29

4M ago39:29

39:29

The Journal of Inherited Metabolic Disease Editorial Committee come together to talk about the direction of metabolic medicine, the dangers and potential of AI, impact factors, reviewing papers and their publication hopes for 2024. There's also a little metabolic quiz, allowing you to pit your wits against the committee. Featuring: Shamima Rahman, …

1
Mike & Amit talk 2024: Our predictions for the new year 29:57

4M ago29:57

29:57

From deepfakes to AI assistants, the technology of tomorrow may help or hinder the world depending on whose hands it's in. In the final episode of 2023, Mike and Amit discuss what to expect in the coming year, and give their predictions over how to prepare. ********* Michael Wade is a Professor of Innovation and Strategy and Director of the IMD Glo…

1
Shortcast: Relationship between plasma & capillary blood Phe using volumetric collection devices 4:25

4M ago4:25

4:25

Blood spots are integral to disease monitoring in PKU, however, there are concerns regarding correlation between capillary and plasma levels and discrepancies arising based on sampling quality and storage. Dr Rachel Carling explains how a volumetric blood collection device presents a cost effective way to improve consistency and reduce rejected sam…

1
Capital Conversations: Olivier Laplace on the Technology Investment Market 17:06

5M ago17:06

17:06

In episode one of Capital Conversations, Olivier Laplace, Managing Partner at VI Partners, discusses the evolving landscape of the technology investment market. Olivier Laplace explores the nature of the current crisis, drawing parallels to previous downturns and highlighting the unique features of the current situation. His advice to founders cent…

1
Deciphering pathogenicity with CRISPR/Cas9 13:07

4M ago13:07

13:07

In our latest podcast, Antonia Ribes, Frederic Tort, and Gerard Muñoz-Pujol discuss CRISPR/Cas9 based technique for the validation of genetic variants requiring just the genetic data. CRISPR/Cas9-based functional genomics strategy to decipher the pathogenicity of genetic variants in inherited metabolic disordersGerard Muñoz-Pujol, et alhttps://doi.…

1
Generative AI: What comes next? 20:28

5M ago20:28

20:28

The world has become familiar with artificial intelligence that can answer questions, often in a convincingly human manner. But so far, the technology has been limited by some key constraints. The first is that humans are still required to come up with the initial inputs, or 'prompts', to start conversations or processes. A second is that the relat…

1
S7 Episode 8 – The Peat Special with Mike Billett author of Peat And Whisky – The Unbreakable Bond 1:00:37

5M ago1:00:37

1:00:37

The 2 Gordon’s welcome scientist turned author, Mike Billet who has spent more than 20 years working and researching as a peatland scientist. He gives a fascinating insight into his highly acclaimed new book which Charles Maclean is quoted on the front cover as saying, “I believe this to be amongst the most important books about whisky ever written…

1
Introducing... Capital Conversations: Insights into the world of venture capital 2:40

5M ago2:40

2:40

Capital Conversations: Insights into the world of venture capital is the latest series podcast from IMD and its Venture Asset Management Initiative. Exploring the dynamic realm of venture capital, where innovation meets investment and ideas transform into thriving enterprises. Spotify | Apple | Google Podcasts To subscribe click on the links above,…

1
Shortcast: Grip strength in patients with galactosemia and in a GALT-null rat model 12:00

5M ago12:00

12:00

In the latest Shortcast, Jared J. Druss and Professors Nancy Potter and Judy Fridovich-Keil discuss grip strength in galactosemia (and how competitive boys can bias study results).Grip strength in patients with galactosemia and in a galactose-1-phosphate uridylyltransferase (GALT)-null rat modelJared J. Druss, et alhttps://doi.org/10.1002/jimd.1268…

1
The Interview: Repsol Foundation Chair António Calçada 49:04

5M ago49:04

49:04

Sophie Bacq speaks to António Calçada, Executive Managing Director of the Repsol Foundation, on how the model of corporate philanthropy is shifting from charitable giving towards investing in entrepreneurial ventures that can create positive social and environmental impact. -- Read our new magazine, I by IMD, here. Discover IMD's leadership program…

1
Gene therapy in Glycogen Storage Disorders 13:20

5M ago13:20

13:20

Dr Dwight Koeberl joins the podcast to provide some background to gene therapies in Glycogen Storage Disorders, hi-light some ongoing studies and explain why we owe at least some of our knowledge to a menagerie of animal models. Gene therapy for glycogen storage diseasesDwight D. Koeberl, et alhttps://doi.org/10.1002/jimd.12654…

1
AI ethics and the future of big data 20:14

5M ago20:14

20:14

Since generative AI exploded into public consciousness, people and companies have been worrying about its ethics. But, says Amit Joshi, before considering rogue programs or the replacement of human thought, one must first consider the ABCs of AI ethics. Accuracy is the first big issue. How can one trust or disseminate the work of generative AI when…

1
Shortcast: Screening data for 19 patients with late-onset Pompe disease for a phase I clinical trial 4:29

5M ago4:29

4:29

Dr Will Heath describes insights form screening data derived from 19 patients enrolled in a phase 1 study in late-onset Pompe disease.Screening data from 19 patients with late-onset Pompe disease for a phase I clinical trial of AAV8 vector-mediated gene therapyWilliam B. Hannah, et alhttps://doi.org/10.1002/jmd2.12391…

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