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Talking Flutes

Jean-Paul Wright & Clare Southworth

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Welcome to the dynamic and captivating world of Talking Flutes, the ultimate Flute Podcast Channel that combines simplicity with sensational content. Join us as we unlock the secrets to flute mastery and dive into intriguing conversations with leading flute players, all while sprinkling in mental health awareness, stunning music, laughter, and boundless fun. Picture this: two extraordinary individuals with a passion for the flute come together to create something extraordinary. Meet Clare So ...
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Exploring all things genetics. Dr Patrick Short, University of Cambridge alumnus and CEO of Sano Genetics, analyses the science, interviews the experts, and discusses the latest findings and breakthroughs in genetic research. To find out more about Sano Genetics and its mission to accelerate the future of precision medicine visit: www.sanogenetics.com
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show series
 
0:00 Intro to The Genetics Podcast 01:00 Welcome to Jakob and background on Pheiron 02:14 What made Jakob decide to start Pheiron, what the company does, and how his scientific background inspired him to found a start-up 5:24 Jakob’s excitement and inspiration around the power and potential of machine learning 07:07 Cardiology and heart failure as …
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In the world of music, innovation is the key to keeping the art form alive and evolving. This week, we revisit a transformative episode from 2020 featuring the incredibly talented electric flutist and author, Melissa Keeling. Join us on a journey that will forever change the way you perceive flute performance. Melissa Keeling, a New York-based flut…
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0:00 Introduction 1:40 Andrea’s background and how she got into the field of genetics, neuroimaging, and metabolic disorders 4:00 Insights into Andrea’s clinical practice, including the diverse families and patients she serves and her approach to clinical decision-making 6:30 How genetics and genomics have changed the diagnostic journey in the last…
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Are you passionate about your flute study and want to know more about what we can learn from sport to develop our skill? Then you won't want to miss the latest episode of 'Talking Flutes Revisited,' where host Clare interviews PGA golf professional Ryan Fenwick. In this episode, Ryan shares his journey from a touring professional PGA golfer to succ…
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0:00 Intro to The Genetics Podcast 01:00 Welcome to Lori Orlando 03:00 Lori’s career: From mathematical modelling to genetics and family history 05:11 The study that revealed 20% of the general population is at a higher risk of disease than average and needs preventative care 07:36 The first five diseases that Lori started analysing through informa…
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0:00 Intro to The Genetics Podcast 1:00 Welcome to Ben Goldacre 02:22 Ben’s open data projects at the Bennett Institute and the challenges they aim to tackle 04:03 Using Electronic Health Records (EHR) to help the National Health Service improve care 06:18 The importance of software development within healthcare data and how to manage salary scales…
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In the world of music, innovation is key to keeping the art form alive and engaging. One such innovator is Greg Pattillo, a name synonymous with the unique blend of beatboxing and flute playing. In a special 'Revisited' episode of "Talking Flutes," hosted by Jean Paul Wright, listeners are treated to an insightful conversation with Greg, who has ov…
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0:00 Intro to The Genetics Podcast. 01:00 Welcome to Michelle. 02:00 Sstop codon diseases and how are they characterised 03:45 Diseases caused by premature stop codons in haploinsufficient genes. 04:35 The role of transfer RNA technology in finding solutions for premature stop codon diseases. 06:16 How Alltrna is engineering tRNAs which can bind to…
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Have you ever been mesmerised by the lilting sound of a flute in an orchestra? On this week's Talking Flutes 'Revisited' podcast episode, Clare had the pleasure over a dodgy Zoom line with Gareth Davis, the principal flautist of the London Symphony Orchestra. His candid conversation takes us on a journey through the high notes and low notes of a pr…
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0:00 Introduction 1:45 Almut’s research experience, including two recent publications on genome-scale metabolic reconstruction human microorganisms Genome-scale metabolic reconstruction of 7,302 human microorganisms for personalized medicine APOLLO: A genome-scale metabolic reconstruction resource of 247,092 diverse human microbes spanning multiple…
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In the realm of music, the flute holds a special place, weaving melodies that can be both hauntingly beautiful and strikingly powerful. In the latest episode of Talking Flutes, we revisit a gem from our archives featuring none other than the renowned flute player Paul Edmund-Davies. His insights into the world of flute playing are as refreshing as …
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0:00 Intro 1:30 Mavis’ career arc, from starting as a midwife to researching medical innovation and technology with an emphasis on advocacy and equity 7:00 Systemic issues that are easily overlooked in medical research and advancements Webinar: Participant Diversity: Increasing the Impact of Biomedical Research Webinar 10:00 Addressing Eurocentrici…
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Are you a musician looking to carve out your unique space in the industry? Do you ever wonder how you can stand out in a sea of talented performers, teachers, and writers? If you're nodding your head, then the latest episode of Talking Flutes is a must-listen for you! In this insightful 'Revisited' conversation, Clare Southworth and Jean-Paul Wrigh…
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0:00 Introduction 2:00 Allison’s personal journey to researching epilepsy and ring chromosome 20 syndrome 4:00 Biggest challenges families face with ring chromosome 20 syndrome 11:00 Incidence and prevalence of r(20) syndrome, and how we can improve data reliability 21:00 Applying next generation sequencing to r(20) syndrome gene research 29:00 Eng…
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0:00 Introduction 1:30 Ingrid’s initial interests in genetics, paediatrics, and newborn screening 2:45 How the original BabySeq project, a pioneering newborn sequencing program got started, how it’s going, and the launch of BabySeq2 8:45 Lessons from BabySeq1 and goals for BabySeq2 10:30 Potential societal and long-term considerations for those inv…
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Are you ready to discover the 'F word' in music? No, it's not what you think. It's something much more exhilarating – it's FUN! In a delightful episode of Talking Flutes revisited, hosts Jean Paul Wright takes us on a musical journey with the exceptional talents of Jose Valentino (flute) and Gualo (guitar). The podcast revisits a gem from March 201…
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0:00 Introduction 1:00 The backstory of how Kira first started DNA Today in 2012, when she was still in high school! 3:30 Some of Kira’s favourite topics she has discussed on DNA Today, including the legacy of Henrietta Lacks, and the story of a Glee actress with down syndrome 10:00 Kira’s best practices for podcasting, from over 10 years of experi…
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If the sound of a flute has ever captivated you, our latest podcast episode is one you cannot afford to miss. in October 2020 we had the immense pleasure of welcoming Sir James and Lady Jeanne Galway, a couple who have not only mastered the art of flute playing but have also dedicated their lives to the education and continuation of this enchanting…
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0:00 Introduction 2:00 The value of an English Literature degree in designing and analysing research studies in medicine 3:45 Emma’s entrance to pharmacogenomics and her transition from practising physician to genetics research 6:00 How the East London Genes and Health program is increasing representation of diverse populations, namely South Asians…
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In this week’s enlightening episode of Talking Flutes Extra, host Jean Paul welcomes back Dr. Beth Wright, forensic psychologist and his daughter, to tackle a question that hits home for many musicians – dealing with impostor syndrome and self-doubt. With her expert insight, Dr. Beth Wright demystifies the concept of impostor syndrome, describing i…
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0:00 Introduction 1:00 George’s upcoming big projects, including developing full recycling, renewing energy, creating bioweather maps, and harnessing citizen science 6:45 Progress in engineering viral resistance in humans, including thoughts from pre- and post- pandemic 11:00 A swapped genetic code that prevents viral infections and gene transfer b…
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Stress vs Anxiety in our musical performance! As musicians, the stage is not only a platform for showcasing our art but also a battleground for our inner demons of stress and anxiety. In the latest episode of our podcast, we delve deep into this subject with forensic psychologist Dr. Beth Wright, who offers a compelling analysis of the psychologica…
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0:00 Intro 0:40 Jake’s experiences as a serial entrepreneur starting five companies with a basis in genomic science 5:30 Opportunities for research and drug development in the realm of somatic science 9:20 Somatic evolution and how it provides valuable insights into disease mechanisms 12:30 Advantages and disadvantages of studying germline genome-w…
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The Complex Dance of Judgment and Opinion in Musical Performance In this captivating episode of Talking Flutes Extra, host Jean Paul Wright is once again joined by his daughter, forensic psychologist Dr. Beth Wright to delve into the intricate relationship between judgment and the mental and performance outcomes for musicians. The discussion kicks …
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Show Notes: 0:00 Introduction 1:20 How polydactyl mutations can inform research on non-coding variant mechanisms The importance of low-affinity binding between transcription factors and targets How these lessons can help us improve our understanding of drug and target discovery See Veera’s January round-up for more information: https://www.gwasstor…
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Navigating Procrastination with Dr. Beth Wright In this enlightening episode of Talking Flutes, host Jean Paul Wright is joined by Dr. Beth Wright, a flute player and forensic psychologist, to unravel the complexities of procrastination, especially as it relates to musicians. As the first in a short series focused on musician mental health and awar…
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0:00 Introduction 0:45 Jean’s personal experiences with family members with genetic ALS 10:00 Jean’s thoughts on the barriers and facilitators to providing treatment for those with genetic ALS 13:20 Insights into C9orf72, a common genetic determinant of ALS, and how it can also be associated with FTD 16:10 Jean’s experiences as an active advocate f…
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The Flute Pad Revolution: A Symphony of Sustainability Are you a flute enthusiast always on the lookout for the next big thing in instrument care and maintenance? Well, prepare to be blown away by a recent innovation that's been the talk of the flute world, albeit in hushed tones until now. Welcome to the world of Poriflola, a groundbreaking paddin…
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0:00 Introduction 1:05 Insights into the PD GENEration’s (a programme from the Parkinson's Foundation) milestones and progress points for the upcoming year 3:30 The shifting attitudes and perspectives of neurologists and healthcare workers at the PD GENEration 5:50 Insights into Nacho’s work with the genetics of Parkinson’s disease 10:20 Barriers a…
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"People don't respond to what you do, they respond to why you do it." This is a brilliant sax player perspective for every instrumentalist!Unleashing Creativity: The Musician's Perspective! Episode 306 In this captivating episode of the 'Talking Flutes' Podcast this week, Jean-Paul Wright ventures outside the realm of flutes to sit down with the mu…
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0:00 Intro 0:25 Mazen’s lifelong commitment to furthering the field of precision medicine in liver disease research, fueled by a personal connection of his grandmother developing MASH cirrhosis 2:30 Breakthroughs in the field of metabolic dysfunction-associated steatotic liver disease (MASLD) since the beginning of Mazen’s career 5:30 The potential…
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As musicians, we often find ourselves caught up in a whirlwind of rehearsals, performances, and the pursuit of perfection. But have you ever stopped to consider where your sense of self-worth lies amidst this relentless chase? This is the heart of our latest podcast episode. In a candid conversation, Jean Paul Wright guides us through the often-ove…
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0:00 Introduction 0:25 Julia’s personal experience with ultra-rare diseases within her family 10:25 The importance of increasing accessibility to genetic testing across populations to learn more about ultra-rare diseases 14:00 The origin story of Rare Trait Hope Fund 23:50 Current research and next steps in developing potential gene therapies for a…
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Spicing up your relationship with the flute! Extended techniques expand the palette of flute learning and playing. "The benefits of using extended techniques to improve your flute playing This week on 'Talking Flutes' Jean-Paul speaks with Dr Mary Matthews and Nicole Chamberlain about their latest publication 'Into The Beyond', a method book for fl…
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0:00 Introduction 1:25 How Lord O’Shaughnessy became involved in scientific policy making and his path to writing the UK Commercial Clinical Trials Review. 04:05 How Lord O’Shaughnessy pivoted from education to a focus on life sciences 06:38 The biggest challenges Lord O’Shaughnessy faced during his time as Parliamentary Under Secretary for Health …
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How to break free from the shackles of comparison! In the intricate tapestry of musical expression, the quest to be true to oneself often encounters a formidable obstacle—comparison. The impulse to measure one's musical journey against others can hinder creativity, stifle growth, and erode the joy of making music. In this short podcast recorded on …
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0:00 Introduction 01:10 How growing up in Malawi planted the seeds for John’s career in medicine and transition to therapeutic development 04:35 Why John focuses on rare diseases and conditions such as asthma 06:01 What has changed over the last decade in terms of treating and understanding asthma and the progress that genetics has enabled 07:31 Wh…
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Transformative Notes from Death Row! In Talking Flutes Extra podcast this week Jean-Paul has a fascinating discussion with musician, composer, flute player and activist Elsa Nilsson. We start with the power of improvisation. The podcast then moves on to a composition using the voice of 'Maya Angelou' with 'The Band of Pulses' and we end with the st…
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0:00 Introduction 0:50 Holly’s background and career so far 03:30 Complex decision-making and multiple risk factors: Family history, genetics, phenotypes and beyond 07:05 Changes within the last decade to help people make complex, sometimes subjective, healthcare decisions 09:20 Impact on people: The RTI’s mission and the Early Check Study 13:45 Ne…
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Gosh we made it! Join us as we celebrate our 300th episode of Talking Flutes! In this special podcast, we'll reveal the secrets behind our success and share some behind-the-scenes stories from our journey as flutists and podcasters. Whether you're a flute player, a musician, or just a fan of podcasts, you won't want to miss this episode! When we be…
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Summary: 0:00 Introduction 01:01 How Leslie got into the field of synthetic biology and engineering, and her career journey so far 02:45 What Leslie accomplished during her postdoc and recent transformations in the field of genomics 05:57 The impacts of non-coding regions of the genome and the outcome of deletions 08:20 How long it takes to make ch…
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Taming the Musical Control Freak: Unleashing Creativity and Achieving Musical Excellence! As we all know, music, a universal language that transcends boundaries and stirs the soul, has the power to evoke emotions, inspire creativity, and connect us on a deep level. For many musicians, even if you don’t do if professionally, it becomes a lifelong pa…
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Summary: 0:00 Introduction 0:50 Reflections from the 34th International Symposium on ALS/MND in Basel 1:50 Michael’s professional journey, initial challenges he encountered, and how the field of neurology has evolved over the years 3:10 An introduction to the ALS landscape, including its presentation, the genes involved, and potential treatment opt…
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To make the contrabass sound when you want you sometimes have to hit the notes two measures away 😂 This week at a very noisy NAMM Show, the worlds biggest musical instrument and technology show in Anaheim, California, Jean-Paul speaks with flute player, educator, repairer, maker and self confessed flute nerd Dr Keith Hanlon about 'The Flute Examine…
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0:00 Introduction to Dr. Nicole Paulk, a pioneer in AAV research and the founder of Siren Biotechnology 0:50 The moments that shaped Nicole’s career path and her passion for gene therapy and AAV research 9:20 Nicole’s academic research career and her transition from academia to the biotech industry 23:00 The story behind the founding of Siren Biote…
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"Failure is feedback - feedback is knowledge - knowledge is power!" This week Clare is talking about the role of teachers, hobbies and mentorship. Listen to the complete 8 minute podcast and you'll hear Clare (retired Flute Professor at the prestigious Royal Academy of Music in London) making you a wonderful offer!! 'Talking Flutes', Talking Flutes…
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0:00 Introduction 01:00 Chris’ background and career to date 02:10 What is the Enigma Project? 04:48 How is genetics being applied to drug discovery today and how does proteomics fit in? 09:23 When the UKBiobank Pharma Proteomics Project began and how long it took to set up 10:57 54k UK Biobank participants tested - discussion of findings 14:33 The…
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Welcome to an exploration into the profound world of mindfulness. This practice, celebrated as a remedy for the strains of our modern lives, has gained significant popularity. But, as musicians, it's crucial to scrutinise the claims surrounding mindfulness and discern how it seamlessly intertwines with our musical journeys. In this Talking Flutes '…
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Summary: 0:00 Introduction 5:45 Lessons learned from 15 years at GSK: How has genetics and drug discovery evolved over time? 8:10 Matt’s seminal 2015 paper: Quantifying the impact of human genetic evidence on the probability of success in drug development 11:40 Which types of genetic evidence are the best drivers of success in clinical trials? 13:3…
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"Tension and release draws the audience in and unlocks the narrative of the piece you're playing..." This week on 'Talking Flutes Extra' Jean-Paul speaks with the fabulous musician, flute player, composer and educator Hadar Noiberg. During this nearly hr long podcast they cover so many areas of performance and practice from 'Finding your authentic …
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