How can we, humans, look at our relationship to nature differently? In season three of Going Wild, on top of stories about animals, we invite you to journey through the entire ecological web — from the tiniest of life forms to apex predators — alongside the scientists, activists and adventurers who study it. Wildlife biologist and host Dr. Rae Wynn-Grant has been studying wild animals in their natural habitats all over the world for years. Our award-winning podcast takes you inside the hidde ...
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EP 143: Harnessing human data in drug development with Jakob Steinfeldt, Co-Founder and Chief Scientific Officer at Pheiron
MP3•Episode home
Manage episode 429413366 series 2631947
Content provided by Sano Genetics. All podcast content including episodes, graphics, and podcast descriptions are uploaded and provided directly by Sano Genetics or their podcast platform partner. If you believe someone is using your copyrighted work without your permission, you can follow the process outlined here https://player.fm/legal.
0:00 Intro to The Genetics Podcast
01:00 Welcome to Jakob and background on Pheiron
02:14 What made Jakob decide to start Pheiron, what the company does, and how his scientific background inspired him to found a start-up
5:24 Jakob’s excitement and inspiration around the power and potential of machine learning
07:07 Cardiology and heart failure as an example of the gap between where research needs to be compared to where it is today
10:52 Why creating the GPS for identifying patients at increased risk of disease is a challenge on multiple fronts
12:42 How Pheiron’s approach and specificity is opening up the possibility of identifying highly-relevant patients and running clinical trials at greater pace
17.35 How testing potential treatments in a highly-specific population affects the design of Phase 3 clinical trials
21:19 The types of data required to build Pheiron’s GPS - from population scale insights to deep analysis within subgroups
23:48 Whether there is a shortage of healthcare systems with robust research arms looking to participate in such collaborations
27:30 Working with patients to build a collaborative commitment to data sharing
28:22 Making the decision to start Pheiron rather than continue working in medicine or research
30:38 Core learnings from building a company from the ground up
31:35 What Jakob is currently most focused on and what he hopes to achieve with Phieron in the immediate future
34:40 Closing remarks
Please consider rating and reviewing us on your chosen podcast listening platform!
Find out more:
Find Jakob on Twitter (X)
176 episodes
MP3•Episode home
Manage episode 429413366 series 2631947
Content provided by Sano Genetics. All podcast content including episodes, graphics, and podcast descriptions are uploaded and provided directly by Sano Genetics or their podcast platform partner. If you believe someone is using your copyrighted work without your permission, you can follow the process outlined here https://player.fm/legal.
0:00 Intro to The Genetics Podcast
01:00 Welcome to Jakob and background on Pheiron
02:14 What made Jakob decide to start Pheiron, what the company does, and how his scientific background inspired him to found a start-up
5:24 Jakob’s excitement and inspiration around the power and potential of machine learning
07:07 Cardiology and heart failure as an example of the gap between where research needs to be compared to where it is today
10:52 Why creating the GPS for identifying patients at increased risk of disease is a challenge on multiple fronts
12:42 How Pheiron’s approach and specificity is opening up the possibility of identifying highly-relevant patients and running clinical trials at greater pace
17.35 How testing potential treatments in a highly-specific population affects the design of Phase 3 clinical trials
21:19 The types of data required to build Pheiron’s GPS - from population scale insights to deep analysis within subgroups
23:48 Whether there is a shortage of healthcare systems with robust research arms looking to participate in such collaborations
27:30 Working with patients to build a collaborative commitment to data sharing
28:22 Making the decision to start Pheiron rather than continue working in medicine or research
30:38 Core learnings from building a company from the ground up
31:35 What Jakob is currently most focused on and what he hopes to achieve with Phieron in the immediate future
34:40 Closing remarks
Please consider rating and reviewing us on your chosen podcast listening platform!
Find out more:
Find Jakob on Twitter (X)
176 episodes
All episodes
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