show episodes
 
This Week in Microbiology is a podcast about unseen life on Earth hosted by Vincent Racaniello and friends. Following in the path of his successful shows 'This Week in Virology' (TWiV) and 'This Week in Parasitism' (TWiP), Racaniello and guests produce an informal yet informative conversation about microbes which is accessible to everyone, no matter what their science background.
 
A video podcast by the American Society for Microbiology that highlights the latest in microbiology, life science and biotechnology news. ASM is composed of over 42,000 scientists and health professionals with the mission to advance the microbial sciences as a vehicle for understanding life processes and to apply and communicate this knowledge for the improvement of health and environmental and economic well-being worldwide. For information about ASM and MicrobeWorld, visit us online at www. ...
 
A video podcast by the American Society for Microbiology that highlights the latest in microbiology, life science and biotechnology news. ASM is composed of over 42,000 scientists and health professionals with the mission to advance the microbial sciences as a vehicle for understanding life processes and to apply and communicate this knowledge for the improvement of health and environmental and economic well-being worldwide. For information about ASM and MicrobeWorld, visit us online at www. ...
 
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show series
 
The TWiM team explores how delivery of an enzyme into competitor cells leads to synthesis of (p)ppApp, depletion of ATP, deregulation of metabolic pathways, and cell death, and a refinement of our typical view of bacterial lag phase as a period of nonreplication. Become a patron of TWiM. Links for this episode: Killing competitors by synthesis of (…
 
The TWiM team reveals the genetic mysteries of the Dead Sea Scrolls from sequencing of DNA, and 100 million year old living bacteria recovered from marine sediments. Hosts: Vincent Racaniello, Elio Schaechter, Michele Swanson and Michael Schmidt Become a patron of TWiM. Links for this episode: Elio’s Memoirs Genetic mysteries of Dead Sea Scrolls (C…
 
The TWiMmers explore detection of SARS-CoV-2 on surfaces in an ophthalmology examination room, the ability of stressed populations of Yersinia bacteria to survive antimicrobial treatment within host tissues, and how volatile organic chemicals produced by soil microbes attract arthropods which in turn disperse bacterial spores. Subscribe to TWiM (fr…
 
Mark Martin joins TWiM to describe nano-sized parasitic bacteria that inhabit humans, and the construction of whole-cell biosensors for detecting arsenic in drinking water. Hosts: Vincent Racaniello, Elio Schaechter, and Michael Schmidt Guest: Mark O. Martin Subscribe to TWiM (free) on Apple Podcasts, Google Podcasts, Android, RSS, or by email. Bec…
 
TWiM reveals a potential mucus-busting weapon for patients with cystic fibrosis, and bacteria in the intestinal tract that can oxidize cholesterol, leading to lower levels of the lipid in blood. Subscribe to TWiM (free) on Apple Podcasts, Google Podcasts, Android, RSS, or by email. Become a patron of TWiM. Links for this episode Biofilm eradication…
 
TWiM reveals that methane-producing bacteria might survive beneath the surface of Mars, and identification of a cytopathogenic toxin in a bacterium associated with preterm birth. Hosts: Vincent Racaniello, Elio Schaechter, Michele Swanson and Michael Schmidt Become a patron of TWiM. Links for this episode: Archaea could make methane on Mars (Sci Re…
 
The TWiM discusses eradicating racism in academia and STEM, and a peptide from commensal bacteria that protects skin from damage caused by MRSA Become a patron of TWiM Links for this episode: Responsibility in academic research Improving equity in faculty hiring (MBoC) #ShutDownSTEM Peptide protects skin from microbial damage (AAC) Agr phase varian…
 
The TWiM team explains how breathing can transmit SARS-CoV-2, and how lack of breathing leads to loss of mitochondria in a multicellular parasitic animal. Become a patron of TWiM. Links for this episode: Reducing transmission of SARS-CoV-2 (Science) Why social distancing is important (NY Times) Parasite without mitochondria (PNAS) Letters read on T…
 
The TWiM team explains an experimental vaccine to prevent E. coli urinary tract infections, and the remarkable three-way symbiosis of narnaviruses, bacteria, and fungi. Subscribe to TWiM (free) on Apple Podcasts, Google Podcasts, Android, RSS, or by email. Become a patron of TWiM. Links for this episode Developing a vaccine for UTI (mBio) Narnaviru…
 
The TWiM team discuses saliva as more sensitive for SARS-CoV-2 detection in COVID-19 patients than nasopharyngeal swab and how Mycobacterium tuberculosis sulfolipid-1 activates nociceptive neurons and induces cough. Links for this episode: Preventing the next pandemic (NY Times) COVID-19 treatment guidelines (NIH) Saliva sensitive for SARS-CoV-2 de…
 
A ferret model for infection by SARS-CoV-2, and how Neolithization lead to emergence of a human bacterial pathogen. Hosts: Vincent Racaniello, Elio Schaechter, Michele Swanson and Michael Schmidt Links for this episode: Infection and transmission of SARS-CoV-2 in ferrets (Cell Host Micr) Neolithization led to emergence of Salmonella enterica (Nat E…
 
Vincent, Elio and Michael reveal the ASM COVID-19 summit, and how Salmonella injects a protein into the cell to drive suppression of the immune response. ASM COVID-19 Summit Value of SARS-CoV-2 diagnostic testing (mBio) How SARS-CoV-2 is changing (nextstrain) Contribute to COVID-19 data Salmonella effector suppresses inflammation (Cell Host Micr) S…
 
Vincent, Elio and Michael discuss the stability of human coronaviruses on surfaces and in aerosols, and peptidoglycan production by a mosaic consisting of a bacterium within a bacterium within an insect. Links for this episode: Human coronavirus 229E infectivity on common surfaces (mBio) Aerosol and surface stability of SARS-CoV-2 (medRxiv) Peptido…
 
The most common analogy for CRISPR systems is that of molecular scissors. Joe Bondy-Denomy offers an alternative analogy from the bacteriophage perspective, all based on scientific data. 👍 Subscribe to ASM's YouTube channel 🔬 Learn more about the American Society for Microbiology at asm.org ✅ Become a member today at asmscience.org/join 📱 Join us o…
 
The TWiM team reviews the coronavirus outbreak that began in Wuhan, China, and the finding that an IRF deficiency underlies Whipple’s disease. 2019-nCoV case tracking (JHU) Clinical features of infection with 2019-nCoV (Lancet) Early transmission dynamics of 2019-nCoV (NEJM) Isolation of 2019-nCoV (NEJM) TLR4 defect in Whipple’s disease (eLife) Bec…
 
We may not see microplastics, but they are all around us. These microplastics play a role in shaping the microbial environment, and this talk will explain how. 👍 Subscribe to ASM's YouTube channel at https://goo.gl/mOVHlK 🔬 Learn more about the American Society for Microbiology at http://www.asm.org ✅ Become a member today at http://www.asmscience.…
 
The Fellowship of the TWiM reveal that colorectal cancer-associated microbiota are associated with higher numbers of methylated genes in colonic mucosa, and identification of metabolites needed by the fire blight disease bacterium for virulence in apples. Become a patron of TWiM. Links for this episode: Colorectal cancer and the gut microbiome (PNA…
 
The Microbial Comrades present the oldest osteosynthesis in history, and how a small molecule produced by stressed bacteria is a warning signal that repels healthy populations to promote their survival. Hosts: Vincent Racaniello, Elio Schaechter, Michele Swanson and Michael Schmidt Subscribe to TWiM (free) on Apple Podcasts, Google Podcasts, Androi…
 
The TWiM team reveals how ribosome modification resuscitates bacterial persister cells, and explain how a phage tail fiber protein exploits rotation of flagella to move towards the cell membrane. Become a patron of TWiM. Links for this episode: Ribosome modification resuscitates persister cells (Environ Micro) Flagellotrophic phage targets host wit…
 
Hosts: Vincent Racaniello, Michele Swanson and Michael Schmidt Guests: Deanna Beatty, Mark Hay, Gina Lewin, Frank Stewart, and Marvin Whiteley At Georgia Tech, members and trainees of the Center for Microbial Dynamics and Infection discuss the identification of pathogen essential genes during coinfections, and how coral management can improve coral…
 
From ASM Microbe 2019 in San Francisco, Vincent speaks with Victoria McGovern, Carl Nathan, and Dan Portnoy about advancing human health through innovative collaborations. Host: Vincent Racaniello Guests: Victoria McGovern, Carl Nathan, and Dan Portnoy Links for this episode: Getting grants (Virulence) Nitric oxide synthase protects against tubercu…
 
The TWiM holobionts pay tribute to Stuart Levy, and reveal the remarkably diverse array of cyclic nucleotides synthesized by bacteria that likely mediate interactions with animal and plant hosts. Become a patron of TWiM. Links for this episode: Stuart Levy, Antibiotic Resistance Researcher, Dies Resistance fighter (The Scientist) Stuart Levy on TWi…
 
The tetracoccal TWiM team visits Tardigrades on the Moon, and the twelve year quest to isolate an archaeon that provides insights into the emergence of the first eukaryotic cell. Links for this episode: Tardigrades on the moon (Mashable) Meet the Tardigrade (WaPo) Archaeon at prokaryote-eukaryote interface (bioRxiv) Subscribe to TWiM (free) on iTun…
 
Host: Vincent Racaniello Guests: Nicholas Arpaia and Tal Danino Vincent meets up with Nick and Tal to explain how they engineered E. coli to lyse within tumors and deliver an antibody that causes tumor regression in mice. Links for this episode: Programmable bacteria induce tumor immunity (Nat Med) Synchronized cycles of bacterial lysis (Nature) TW…
 
The TWiM team reveals thousands of small novel genes in the human microbiome, and a mutualistic symbiosis between marine protists covered with magnetosome-containing bacteria. Hosts: Vincent Racaniello, Elio Schaechter, Michele Swanson and Michael Schmidt Links for this episode Thousands of small novel genesin human microbiome (Cell) A magnetotacti…
 
Hosts: Vincent Racaniello, Elio Schaechter, Michele Swanson and Michael Schmidt Guest: Julie Wolf Julie joins the TWiM team to reveal how microbiome and gut anatomy of a wood-feeding beetle promotes lignocellulose deconstruction, and bacteria that degrade PET plastic. How wood-feeding beetles deconstruct lignocellulose (PNAS) Meet the Microbiologis…
 
Mark Martin joins Vincent and Michael to present compelling papers suitable for teaching microbiology to undergraduate students. Become a patron of TWiM. Links for this episode: Paradigm shifts, paradigm drifts (pdf) Introducing THOR (mBio) Engineering bacteriophages to treat mycobacterial infection (Nat Med) Biofilms by Colter (Int Microbiol) Life…
 
Vincent, Michele, and Michael travel to San Diego to reminisce with Elio about his career, his work in microbiology, and his love for microbes and mushrooms. VIDEO VERSION AVAILABLE: https://www.youtube.com/watch?v=Menlo1YvPko Subscribe to TWiM (free) on Apple Podcasts, Google Podcasts, Android, RSS, or by email.Get the entire ASM Podcast Network v…
 
From ASM Microbe 2019, the Microbials meet up with Susanna L. Harris and Alex Politis to talk about mental health in graduate school and NIH peer review. Hosts: Vincent Racaniello, Michele Swansonand Michael Schmidt Guests: Susanna L. Harrisand Alex Politis Subscribe to TWiM (free) on Apple Podcasts, Google Podcasts, Android, RSS, or by email. Get …
 
The TWiM team presents an extracellular bacterium associated with Paramecium, and induction of antiviral immunity by a bacteriophage that prevents bacterial clearance. Subscribe to TWiM (free) on iTunes, Google Podcasts, Stitcher, Android, RSS, or by email. You can also listen on your mobile device with the Microbeworld app. Become a Patron of TWiM…
 
The Microbials reveal how a chemosynthetic symbiont stores energy for its marine flatworm host, and extraction of nutrients from host cells by E. coli injectisome components. Become a patron of TWiM. Links for this episode: Take the TWiM listener survey Bacteria store energy for gutless worms (PNAS) Paracatenula on TWiM #21 E. coli extracts nutrien…
 
The Microbials discuss how ambrosia beetles utilize ethanol to farm fungi, and how cleaved cochlin protein sequesters bacteria in the inner ear to preserve hearing function. Links for this episode: Ambrosia beetles, ethanol, and farmed fungi (PNAS) Cleaved cochlin protects the inner ear (Cell Host Microbe) Importance of flossing (ADA) Subscribe to …
 
Michael and Vincent discuss the finding of immunity to Cas9 protein in humans, and a potential role for an oral bacterium in Alzheimer’s disease. Subscribe to TWiM (free) on Apple Podcasts, Google Podcasts, Android, RSS, or by email.Get the entire ASM Podcast Network via our Microbeworld app. Become a patron of TWiM. Links for this episode Immunity…
 
Vincent Racaniello, Michael Schmidt, Michele Swanson and Elio Schaechter How a bacterium helps dengue virus replicate in the mosquito gut, and minicells as a damage disposal mechanism in E. coli. Become a patron of TWiM. Links: Please take the TWiM listener survey Bacteria help dengue virus in mosquito gut (Cell Host Micr) Fungus helps dengue virus…
 
The TWiM team explore how Lactobacillus reuteri can rescue social deficits in three mouse models of autism spectrum disorder, and the role of Salmonella persisters in undermining host defenses during antibiotic treatment. Subscribe to TWiM (free) on iTunes, Google Podcasts, Stitcher, Android, RSS, or by email. Become a Patron of TWiM! Please take t…
 
The TWiM team reveals an extremely low rate of mutation in a 2500 year old, 185 acre fungus in Michigan, and how a host-produced quorum sensing autoinducer controls the phage switch between lysis and lysogeny. Please take the TWiM listener survey Vote for NJ State Microbe Huge fungus is 2500 years old (Proc Roy Soc B) Humongous fungus (Wikipedia) H…
 
The TWiM team reveals the oldest human plague from 4,900 years ago in Sweden, and engineering E. coli to become an endosymbiont in yeast, modeling the evolution of mitochondria. Hosts: Vincent Racaniello, Elio Schaechter, Michael Schmidt, and Michele Swanson Subscribe to TWiM (free) on Apple Podcasts, Google Podcasts, Android, RSS, or by email. Get…
 
The TWiM-opods consider two stories about exosomes, vesicles that are shed from cells: those that eliminate airway pathogens, and those from the plants we eat that shape our gut microbiome. Hosts: Vincent Racaniello, Michael Schmidt, and Michele Swanson. Subscribe to TWiM (free) on Apple Podcasts, Google Podcasts, Android, RSS, or by email. Get the…
 
The TWiM team considers the state of the world’s fungi as revealed by a report from the Kew Royal Botanical Gardens, and how Salmonella loses motility to evade host defenses. Hosts: Vincent Racaniello, Michael Schmidt, Elio Schaechter, and Michele Swanson Take our listener survey. Thanks! asm.org/twimpoll Subscribe to TWiM (free) on iTunes, Google …
 
The TWiM rock stars show how to modify gram-positive antibiotics so they can kill gram-negative cells, and bacteria that have both DNA and RNA in their genome. Hosts: Vincent Racaniello and Michael Schmidt Links for this episode Antibiotics for gram-positives that kill gram-negatives (J Med Chem) Sideromycin commentary (Am Council Sci Health) Bacte…
 
The TWiM people reveal that phages must cooperate to overcome CRISPR-Cas defenses, and the effect of the herbicide glyphosate on the gut microbiome of honey bees. Hosts: Vincent Racaniello, Elio Schaechter, Michael Schmidt, and Michele Swanson Subscribe to TWiM (free) on iTunes, Google Podcasts, Stitcher, Android, RSS, or by email. You can also lis…
 
The TWiM team describe the involvement of a microbiome in snail metamorphosis, and using Listeria to kill tumors. Hosts: Vincent Racaniello, Michael Schmidt, and Michele Swanson. Subscribe to TWiM (free) on Apple Podcasts, Google Podcasts, Android, RSS, or by email. Get the entire ASM Podcast Network via our Microbeworld app. Become a Patron of TWi…
 
The TWiM team considers the increasing tolerance of Enterococcus to handwash alcohols, and how the study of DNA in ancient dung reveals the diet and parasite burden of extinct New Zealand birds. Subscribe to TWiM (free) on iTunes, Google Podcasts, Stitcher, Android, RSS, or by email. You can also listen on your mobile device with the Microbeworld a…
 
Sam Sternberg discusses his work on exploring and exploiting CRISPR-Cas immune systems, beginning as a graduate student with Jennifer Doudna, at a biotech start-up, and in his laboratory at Columbia University. Host: Vincent Racaniello Guest: Sam Sternberg Become a Patron of TWiM! Links for this episode Sternberg Laboratory at Columbia Mechanism of…
 
The TWiMpeeps discuss two symbioses: a parasitoid bacterium of a heterotrophic protist, and fungal parasites in cicadas. Become a patron of TWiM. Links for this episode: Parasitoid bacterium of protist (bioRxiv) Fungal symbiont recruitment in cicadas (PNAS) Fly by virus (TWiEVO 33) The Atlantic “How to Tame a Zombie Fungus” by Ed Yong Image credit …
 
The TWiM hosts reveal how to test antimicrobial susceptibility in less than 30 minutes, and a carbonate-sensitive phytotransferrin in diatoms that controls iron uptake. Become a Patron of TWiM! Links for this episode: Legionnaire’s Disease with Michele Swanson Antibiotic susceptibility in less than 30 min (PNAS) S. saprophyticus growing in microflu…
 
Science communication experts discuss creative ways (like variations of escape-the-room, the Up-Goer Five Challenge, or edible learning aids) to get people to interact with science. Jennifer Gardy, Kathryn (KT) Elliott, and Dave Westenberg discuss the inspiration for their creative approaches and tips for other who want to improve their scicomm ski…
 
Vincent speaks with John Warhol about state microbes, the Periodic Table of the Microbes, and why microbiology is cooler than astrophysics, but they have better TV shows. Host: Vincent Racaniello Guest: John Warhol Subscribe to TWiM (free) on Apple Podcasts, Google Podcasts, Android, RSS, or by email. Get the entire ASM Podcast Network via our Micr…
 
CDC Principal Deputy Director Anne Schuchat has extensive experience in global health and science advocacy. Jennifer Gardy interviews Schuchat about emerging disease threats and what advice for early-career scientists Schuchat can offer. Schuchat talks about translating disease detective work into policies that decrease infection rates, citing the …
 
Vincent speaks with Mark O. Martin about microbial centricity, teaching undergraduates microbiology, lux art, painting with glowing bacteria, tardigrades and much more at ASM Microbe 2018. Host: Vincent Racaniello Guest: Mark O. Martin Subscribe to TWiM (free) on Apple Podcasts, Google Podcasts, Android, RSS, or by email. Get the entire ASM Podcast…
 
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